• 컴퓨터교육학회논문지
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• 제14권6호
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• pp.19-30
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• 2011

본 연구에서는 $21^{st}$ Century Skills와 Computational thinking의 관점에서 컴퓨터 교육의 특성을 분석하고자 하였다. $21^{st}$ Century Skills는 현세계에서 성공적인 삶을 살아가기 위한 필수 능력으로 학습과 관련하여 비판적 사고, 문제 해결 능력, 통신 능력과 협동 능력이 포함되어 있다. Computational thinking은 오늘날 융합 시대에 요구되는 기초 능력이라 할 수 있으며, 컴퓨터과학 교육의 핵심 개념이라 할 수 있다. 본 연구에서는 먼저, $21^{st}$ Century Skills와 Computational thinking의 특징을 살펴보고, 이러한 것들이 현재 중 고등학교에서 컴퓨터교육을 위해 운영되고 있는 '정보' 과목의 교육과정과 어떻게 관련이 되는지를 분석하였다. 이를 통하여 초 중 고에서의 컴퓨터 교육에 대한 중요성 및 필요성을 도출해냈다.

• 한국동물위생학회지
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• 제25권3호
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• pp.299-308
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• 2002

The purposes of this study were to characterize the disposition of sulfathiazole(ST) and to investigate the effects of sodium bicarbonate on the disposition of ST in broiler chicks(2.5～3.0kg). Animals were given ST acutely(10～80mg/kg, PO), and plasma, kidney, muscle, heart, liver and spleen samples were collected and analyzed for ST by high performance liquid chromatography. The plasma and tissue data was consistent with a one-compartment pharmacokinetic model. The drug is rapidly but incompletely(2.5～3.87%) absorbed with peak plasma and tissue levels being achieved within one hour after dosing. The plasma and tissue levels depended on drug dosage, and the descending order in concentration of ST was kidney > plasma > heart > muscle $\geq$ spleen $\geq$ liver from animals sacrificed at one hour after dosing. Moreover, significant positive correlations(r>0.9) existed between plasma and tissue levels of ST. In addition, sodium bicarbonate pretreatment decreased plasma level, indicating that an alkalinization stimulate the excretion of ST. Results of this study suggest that oral application of ST was rapidly absorbed and eliminated, and confirmed that tissue residues of ST can be estimated from plasma drug concentration in broiler chicks.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7843-7846
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• 2015

Background: Some matrix metalloproteinases (MMPs) are involved in invasion and metastasis of head and neck squamous cell carcinoma (HNSCC). However, there are few studies on association between stromelysin-2 (ST-2) and invasive behavior of HNSCC. The purpose of this study was to investigate Stromelysin-2 expression by immunohistochemistry. Materials and Methods: This study was conducted on 81 specimens, including 61 HNSCC and 20 non neoplastic epithelium. Sections with 5 micron thickness were prepared and stained with immunohistochemistry technique. Then expression of ST-2 was evaluated according to percentage of stained cells and intensity of staining. Data were analyzed by SPSS (V.21) using Kruskal-Wallis and Tukey tests (P<0.05). Results: The 61 HNSCC specimens were grades I 36.1%, II 34.4% and III 29.5%. The level of ST-2 expressions were moderate (++) and intensive (+++) in 21.3% and 78.7% of tumors, respectively. The ST-2 expression level was only significant between the tumors with grade I and grade III (P=0.016). Tumors presented ST-2 expression with staining intensity of mild 6.6%, moderate 26.2% and strong 67.2%. Staining intensity of ST-2 in grade I tumors was significantly lower than grade II and grade III (P<0.05), and there was no significant difference between grades II and III (P=0.99). Conclusions: According to this study, the expression of ST-2 is associated with histopathological grade and tumor differentiation in HNSCCs.

• Asian Pacific Journal of Cancer Prevention
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• 제16권2호
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• pp.737-740
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• 2015

Purpose: The study aim was to assess factors that impact on the outcome of radioiodine therapy in patients diagnosed with differentiated thyroid carcinoma (DTC). Materials and Methods: We performed a retrospective cohort study on 256 patients with DTC who underwent thyroidectomy and received radioiodine therapy during December 2003 to January 2012. All patients were followed up for at least 1 year. They were considered diseasefree by the criteria of the revised American Thyroid Association Management Guideline for Patients with Thyroid nodules and DTC (ATA guideline 2009). Results: On Cox univariate analysis, factors associated with disease-free status were age<45, stage I tumor, low risk group by histopathology, unifocal tumor involvement, stimulated serum Tg level at 1st dose of radioiodine therapy and no distant metastasis from 1st post-treatment WBS (post RxWBS). On multivariate analysis, stage I tumor and stimulated serum Tg level at 1st dose of radioiodine therapy < 30 ng/mL were the significant prognostic factors that increased disease-free rate by 1.73 times and 2.60 times, respectively (P-value <0.05). Conclusions: Factors affecting the outcome of radioiodine therapy in our study were age, stage, risk of recurrence by histopathology, unifocal tumor involvement and 1st postRxWBS findings. From these factors, stage I tumor and stimulated serum Tg level at 1st dose of radioiodine therapy were independent prognostic factors that substantial increase the disease-free rate.

• 한국학교ㆍ지역보건교육학회지
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• 제23권1호
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• pp.17-27
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• 2022

Objectives: This longitudinal study was done to identify the relationship of school adjustment and sponsor support or future time perspective and the differences of these 3 variables between 1st and 2nd survey of children having Didimseed account in institutional care. Methods: Participants were 25 elementary fourth to sixth grade children who are living on one facility that located in G. metropolitan area at 1st survey and 2nd survey was done at five-year intervals. Data were collected from September 2012 to September 2017 and were analyzed using t-test, paired t-test, ANOVA, post-hoc test and Pearson's correlation coefficients. Results: The level of school adjustment knowledge was not different significantly according to grade, gender and admission period at 1st survey. At 2nd survey, the level of school adjustment was different significantly according to grade only. The level of school adjustment was associated with positive future time perspective(r=.74) and negative future time perspective(r=-.54) at 1st survey, and that was associated with negative future time perspective(r=-.49) and meeting frequency of sponsor(r=-.43) at 2nd survey. There were not significantly different school adjustment and future time perspective variables between both surveys. But meeting frequency of sponsor at 2nd survey was lower significantly than that at 1st survey. Conclusions: Based on the results of this study, it would be necessary to prepare the policies that could have their positive future time perspective to increase school adjustment of institutionalized children. Also the effective strategies to increase not only Didimseed account support but emotional support through qualified meeting with sponsors should be developed.

• Journal of Medicine and Life Science
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• 제21권2호
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• pp.31-39
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• 2024

This study was conducted to determine whether level-1 emergency medical technicians (EMTs) can adequately recognize ST-segment elevation myocardial infarction (STEMI) in the emergency department (ED) and whether their ability to do so differs from that of emergency medicine physicians (EMP). From December 2022 to November 2023, patients aged 20 years or older visiting the ED with chief complaints suggesting acute coronary syndrome (ACS) were enrolled. As soon as the patient arrived at the ED, a level-1 EMT conducted a 12-lead electrocardiogram (ECG) to assess STEMI; an EMP subsequently assessed whether to activate the percutaneous coronary intervention team. Demographic characteristics, test results, and final diagnoses were collected from the medical records. Among the 723 patients with case report forms, 720 were included in the analysis. These were categorized as follows: 117 (16.3%) with STEMI, 159 (22.1%) with non-ST-segment elevation ACS, and 444 (61.7%) with other conditions. STEMI was correctly recognized in 100 patients (91.7%) by level-1 EMTs and in 104 patients (95.4%) by EMPs (kappa=0.646). EMTs with less than 1 year of ED work experience correctly recognized 60 out of 67 STEMI patients (89.6%), which was comparable with the EMPs who recognized 65 out of 67 STEMI patients (97.0%, kappa=0.614). EMTs with more than 1 year of ED work correctly recognized 40 out of 42 STEMI patients (95.2%), and therefore performed better than EMPs, who recognized 39 out of 42 STEMI patients (92.9%, kappa=0.727). The level-1 EMTs adequately recognized STEMI using a 12-lead ECG and were in substantial agreement with the evaluations of the EMPs.

• 대한동의생리학회:학술대회논문집
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• 대한동의생리학회 2005년도 정기총회 및 동계학술대회
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• pp.26-26
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• 2005

• 한국군사과학기술학회지
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• 제13권4호
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• pp.586-593
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• 2010

In this paper, I have proposed that the 1st and 2nd AC-DC transformation methods using multi-level pulsating currents and selection switches. Through making the rectified voltage of the proposed AC-DC translation which is similar to reference voltage by selecting from multi-level pulsating currents, the proposed translation has dramatically reduced the ripple voltage. I have compared the performance of the DC voltage, the ripple voltage and the peak to peak voltage of the proposed method with the conventional method. The simulation results show that the proposed 2nd method has the better performance than the 1st method in the point of average DC voltage drop and peak to peak voltage increase.

• Asian-Australasian Journal of Animal Sciences
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• 제20권2호
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• pp.194-199
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• 2007

Effects of recombinant bovine somatotropin (bST) on plasma hormonal concentration, embryo quality, and pregnancy rate were examined during the superovulation and synchronization treatment in donor and recipient cows. Hanwoos (Korean native beef cattle) were treated with controlled internal drug release (CIDR) combined with bST (CIDR+bST) or without bST (CIDR) as donor cows. The embryos recovered from donors were transferred into Holstein recipient heifers treated with bST (CIDR+bST) or without bST (CIDR) for synchronization. The correlation between IGF-I and P4 showed a positive pattern in the CIDR+bST group (r=0.44, p<0.01), but a negative pattern was shown in the CIDR group (r = -0.59, p<0.02) at day 7 of estrous cycles. Although the number of recovered, transferable, and degenerated embryos was not different, quantities of grade 1 (excellent) embryos in CIDR+bST group were significantly higher than those of the CIDR group (p<0.01). The pregnancy rate was higher in the CIDR+bST recipient group compared to CIDR group (p<0.05), when the embryos were recovered from the donors treated with CIDR. However, the pregnancy was maintained highly in both recipient groups, when the embryos were produced by CIDR+bST treated donors. It can be concluded that bST administration combined with CIDR is an effective method for superovulation and synchronization treatment to stabilize plasma hormonal levels, to obtain excellent quality of embryos, and to get higher pregnancy rate.

• 임상간호연구
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• 제20권2호
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• pp.200-210
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• 2014

Purpose: The main purpose of this study was to effect oral care methods between essential oil gargling and purified water gargling for postoperative patients who had general surgery or orthopedic surgery. Methods: The postoperative patients were assigned to one of two groups. One group gargled with essential oil and the other with purified water. All group gargled three times interval 2 hours. Each patients thirst, oral condition and halitosis were assessed four times. Results: After oral care was provided once, there were significant differences in thirst level between two groups. when oral care was provided once and three times, there were significant differences in oral condition between two groups. but there were no significant differences in halitosis between two groups. Conclusion: The results show that essential oil gargling is a more effective intervention than purified water gargling for post operative patients oral care in reducing the thirst level and improving the condition of the oral cavity.