• The Korean Journal of Physiology and Pharmacology
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• 제5권1호
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• pp.87-92
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• 2001

Carbon monoxide (CO) binds to soluble guanylate cyclase to lead its activation and elicits smooth muscle relaxation. The vascular tissues have a high capacity to produce CO, since heme oxygenase-2 (HO-2) is constitutively expressed in endothelial and smooth muscle cells, and HO-1 can be greatly up-regulated by oxidative stress. Moreover, the substrate of HO, heme, is readily available for catalysis in vascular tissue. Although the activation of heme oxygenase pathway under various stress conditions may provide a defence mechanism in compromised tissues, the specific role of HO-1-derived CO in the control of aortic contractility still remains to be elucidated. The present study was done to determine the effect of HO-1 induction on the aortic contractility. Thus, the effects of incubation of aortic tissue with S-nitroso-N-acetylpenicillamine (SNAP) for 1 hr on the aortic contractile response to phenylephrine were studied. The preincubation with SNAP resulted in depression of the vasoconstrictor response to phenylephrine. This effect was restored by HO inhibitor or methylene blue but not by NOS inhibitor. The attenuation of vascular reactivity by preincubation with SNAP was also revealed in endothelium-free rings. $AlF4^--evoked$ contraction in control did not differ from that in SNP-treated group. These results suggest that increased production of CO was responsible for the reduction of the contractile response to phenylephrine in aortic ring preincubated with SNAP and this effect of SNAP was independent on endothelium.

• The Korean Journal of Pain
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• 제34권1호
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• pp.124-131
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• 2021

Background: Sciatic nerve injury due to intramuscular injection (SNIII) is still a health problem. This study aimed to determine whether there is a correlation between neuropathic pain and electrodiagnostic findings in SNIII. Methods: Patients whose clinical and electrodiagnostic findings were compatible with SNIII participated in this retrospective cohort study. Compound muscle action potential (CMAP) and sensory nerve action potential (SNAP) amplitudes of the sural, superficial peroneal, peroneal, and tibial nerves were graded from 1 to 4. Leeds assessment of neuropathic symptoms and signs scale (LANSS) was applied to all patients. Results: Forty-eight patients were included in the study, 67% of whom had a LANSS score ≥ 12. Sural SNAP amplitude abnormalities were present in 8 (50%) out of 16 patients with a LANSS score < 12, and 28 (87.5%) out of 32 patients with a LANSS score ≥ 12, with significant differences between the groups (P = 0.011). There was a positive correlation between the LANSS score and the sural SNAP amplitude grading (P = 0.001, r = 0.476). A similar positive correlation was also found in the LANSS score and the tibial nerve CMAP amplitude grading (P = 0.004, r = 0.410). Conclusions: This study showed a positive correlation between the severity of tibial nerve CMAP/sural SNAP amplitude abnormality and LANSS score in SNIII. Neuropathic pain may be more common in SNIII patients with sural nerve SNAP amplitude abnormality.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2008년도 정기 학술대회
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• pp.282-287
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• 2008

Since glass-fiber reinforced composite decks have high-strength, light-weight and high durability, many researchs on the composite decks for bridges are currently performed and many composite decks are developed. In this paper, a composite deck with snap-fit connection for pedestrian bridge is developed and studied. A study on behavior of snap-fit connection of composite deck for pedestrian bridge during assembling or disassembling is performed by analysis and experiment.

• 대한치과의사협회지
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• 제56권10호
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• pp.538-547
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• 2018

ITK-SNAP (http://www.itksnap.org) and 3D Slicer (CMFreg extension module; www.slicer.org) are open-source softwares which can be used for superimposition of cone-beam CT images. For superimposition, segmentation of bone is done with ITK-SNAP, and then voxel based superimposition of CBCT images can be performed using 3D Slicer. 3D Slicer has various visualization modules which are not provided in common commercial programs. 'Models' module is used to visualize two overlapping three-dimensional images, and this allows various visualizations by changing view mode and color of the model. In addition, differences between two CBCT images can be represented in a color map using 'ShapePopulationViewer' module. This report introduces how to superimpose and visualize CBCT images using ITK-SNAP and 3D Slicer, and the usefulness and limitations of both softwares will be discussed in comparison with commercial softwares.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2005년도 춘계학술대회논문집
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• pp.662-667
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• 2005

Nonlinear dynamics of active piezolaminated plates are investigated with respect to the thermopiezoelastic behaviors. For largely deformed structures with small strain, the incremental total Lagrangian formulation is presented based on the virtual work principles. A multi field layer wise finite shell element is proposed for assuring high accuracy and non-linearity of displacement, electric and thermal fields. For dynamic consideration of thermopiezoelastic snap through phenomena, the implicit Newmark's scheme with the Newton-Raphson iteration is implemented for the transient response of various piezolaminated models with symmetric or eccentric active layers. The bifurcate thermal buckling of symmetric structural models is first investigated and the characteristics of piezoelectric active responses are studied for finding snap through piezoelectric potentials and the load path tracking map. The thermoelastic stable and unstable postbuckling, thermopiezoelastic snap through phenomena with several attractors are proved using the nonlinear time responses for various initial conditions and damping loss factors. Present results show that thermopiezoelastic snap through phenomena can result in the difficulty of buckling and postbuckling control of intelligent structures.

• Transactions on Electrical and Electronic Materials
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• 제4권2호
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• pp.15-19
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• 2003

In this paper, the new dual trench gate Emitter Switched Thyristor (DTG-EST) is proposed for improving snap-back effect which leads to a lot of serious problems of device applications. Also the parasitic thyristor that is inherent in the conventional EST is completely eliminated in this structure, allowing higher maximum controllable current densities for ESTs. The conventional EST exhibits snap-back with the anode voltage and current density 2.73V and 35A/$\textrm{cm}^2$, respectively. But the proposed DTG-EST exhibits snap-back with the anode voltage and current density 0.96V and 100A/$\textrm{cm}^2$, respectively.

• 한국공작기계학회논문집
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• 제15권6호
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• pp.121-126
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• 2006

Snap-fit is being used in manufacture of plastic products. Integral features using snap-fit are classified as locks, locators and enhancements. Locking features complete the process of attachment by providing physical interference to prevent separation. Looking feature pairs consist of two components, i.e., a flexible latch and a rigid catch and require particular care and attention for their selection. We can make several locking feature pairs by selecting latch and catch, but some parts restrict freedom of selection. Therefore, part designers must know the characteristic properties of generic locking feature forms as considering a specific design problem. In this paper, it has been presented about problem of small size products using locking feature and then introduced new locking feature applicable to small parts.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2003년도 춘계학술대회 논문집 기술교육전문연구회
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• pp.27-30
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• 2003

In this paper, the new dual trench gate Emitter Switched Thyristor (DTG-EST) is proposed for improving snap-back effect which leads to a lot of serious problems of device applications. And the parasitic thyristor that is inherent in the conventional EST is completely eliminated in this structure, allowing higher maximum controllable current densities for ESTs. The conventional EST exhibits snap-back with the anode voltage and current density 2.73V and $35A/cm^2$, respectively. But the proposed DTG-EST exhibits snap-back with the anode voltage and current density 0.96V and $100A/cm^2$, respectively.

• 전산구조공학
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• 제9권3호
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• pp.107-114
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• 1996

비선형 알고리즘으로 "Arc legnth method"를 사용하여 변형률 요소 기법에 의해 구성된 전단 효과를 고려한 곡선보 요소를 이용하여 아치보(arch beam)의 스냅좌굴(snap buckling)현상을 해석함으로써 접선 강성행렬의 선택에 따른 알고리즘의 수렴 특성을 검토하였다. 또한 아치보의 스냅 좌굴현상에서 아치보의 길이와 높이의 비에 따른 스냅 좌굴 진전 특성을 검토하였다.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2010년도 정기 학술대회
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• pp.158-161
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• 2010

고중량, 부식 등의 문제를 안고 있는 목재/강재 리그매트를 대체할 수 있는 고강도 경량 고내구성 특성을 갖는 복합소재 리그매트를 전통 목재 연결방식의 결구시스템을 응용한 새로운 개념의 스냅핏 방식으로 개발하였다. 본 논문에서는 기존에 개발한 리그매트와 이를 개선한 개선형 리그매트의 스냅핏(snap-fit) 연결부의 안전성을 검증하기 위해 연결부 착탈 거동에 대한 해석 및 구조성능 시험을 실시하였고, 그 결과를 비교 분석하여 스냅핏 연결부의 긍정적인 효과를 입증하였다.