• Title/Summary/Keyword: SM Model

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Study of the Effects of Samulhwalhyeol-tang in Hyperlipidemic Animal Model Induced with a High-Fat Diet (고지방 식이로 유발된 고지혈증 동물 모델에서 사물활혈탕(四物活血湯)의 효과 연구)

  • Kang, Seong-Sun;Shin, Yong-Jin;Jo, Jae-Joon;Jeon, Sang-Yun
    • The Journal of Internal Korean Medicine
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    • v.35 no.2
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    • pp.119-132
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    • 2014
  • Objectives : This study was undertaken to investigate the effects of Samulhwalhyeol-tang (SM) in a hyperlipidemic animal model induced by a high-fat diet using diverse biological methods. Methods : This study was to determine whether fractionated EtOH extracts of SM inhibit reactive oxygen species (ROS) and nitric oxide (NO) in RAW 264.7 cells. Hyperlipidemia was induced by a high-fat diet fed for 6 weeks. Total cholesterol, LDL cholesterol, HDL cholesterol, triglyceride, glucose, liver function, cholesterol gene revelation control efficiency, and histologic change of liver were measured after oral administration of SM. Results : 1. Compared to the control group, ROS production (%) and NO production (%) were decreased significantly by SM. 2. Total cholesterol, LDL cholesterol, triglyceride were decreased significantly by SM. 3. HDL cholesterol was increased significantly by SM. 4. Rats' body weight and glucose were decreased significantly by SM. 5. AST, ALP were decreased significantly by SM. 6. In histopathologic examination, fatty liver and fiver fibrosis were inhibited, almost eliminated as round of fat was observed in the liver. Conclusions : SM would appear that effective in the prevention and treatment of atherosclerosis, ischemic heart disease, other cardiovascular diseases, fatty liver and nephrotic syndrome caused by hyperlipidemia.

Design and Application of the u-SM Teaching and Learning Model for an Efficient Ubiquitous Learning (효율적인 유비쿼터스 학습을 위한 u-SM 교수학습모형 설계 및 적용)

  • Kim, Sang-Hong;Joo, Kil-Hong
    • Journal of The Korean Association of Information Education
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    • v.12 no.2
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    • pp.235-244
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    • 2008
  • According to develop the computer and communication technology, recently educational environment is growing to ubiquitous learning with direction which select the studying content, studying time and a studying order oneself. In order to raise effect of studying in the ubiquitous learning(u-Learning), the help or advice of the specialist is necessary earnestly. Accordingly, if it will combine the scaffolding and the mentoring in the u-Learning, a studying effect will be maximize. This paper design the u-SM(Scaffolding and Mentoring) teaching and learning model which applies the scaffolding and e-mentoring. In addition, it embodies and applies the designed u-SM model. Then it examines it affects in studying achievements and attitudes of students and verifies the application possibility of the u-SM teaching and learning.

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Characteristics of Hysteretic Behavior of Circular Steel Column using SM490 for Loading Rate (재하속도에 따른 SM490강재 원형강기둥의 이력거동 특성)

  • Jang, Gab Chul;Chang, Kyong Ho
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.6A
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    • pp.935-941
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    • 2006
  • The hysteretic behavior of steel structure under cyclic and dynami loading such as earthquake is different to that under static loading. Because structural steels on dynamic deformation is different to static deformation with respect with mechanical characteristics and stress-strain relationship. Therefore, to accurately predict the hysteretic behavior of steel structures such as circular steel columns under cyclic and dynamic loading, the difference of loading carrying capacity and deformation according to loading rate, assumed static and dynamic deformation state, must be investigated. In this study, numerical analyses of circular steel column using SM490 for change of loading rate and diameter-thickness ratio(D/t) were carried out by using three-dimensional elastic-plastic finite element analysis and dynamic cyclic plasticity model of SM490 developed by the authors. Characteristics of hysteretic behavior of circular steel column using SM490, load carrying capacity and energy dissipation ratio, were clarified by analysis results.

Antitumor Activity of Salvia miltiorrhiza Herbal Extract in Rat Tumor Model (흰쥐의 종양에 대한 단삼 추출물의 항종양 활성)

  • Park, Hyun-Jeong;Ahn, Sang-Gun;Kim, Jeong-Sang
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.4
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    • pp.400-404
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    • 2007
  • The present study was carried out to investigate the antitumor activity of Salvia miltiorrhiza (SM) herbal extract in rat tumor model. We used a new tumor animal model for the invasion and metastasis of cancer using genetically k-ras-induced rat kidney cells (RK3E-ras). We observed tumor as early as 7 days after the injection of RK3E-ras cells in subcutaneous of Sprague-Dawley rats. All of the rats developed tumor mass at the inoculated site. After 7 days, the experimental groups were divided into two: saline control and injected with SM (200 mg/kg) groups. We investigated tumor's weight, size and hepatic metastasis of each group. Injection of SM herbal extract every other day for 14 days significantly inhibited tumor growth. Histologically, the tumors were undifferentiated carcinoma showing multifactorial necrosis and hemorrhage; also, the tumor invaded into hepatoportal region. Treatment with SM herbal extract caused significant inhibition of tumor cell proliferation. Our data showed that SM herbal extract is effective in controlling the tendency of tumor cell proliferation and metastasis by injection of RK3E-ras cells. These findings provided the potential value of SM as a novel antitumor agent candidate.

Solvent Extraction Separation of Nd and Sm from Chloride Solution with PC88A and Saponified PC88A (鹽酸溶液에서 PC88A와 비누화 PC88A에 의한 Nd와 Sm의 分離推出)

  • Lee, Man-Seung;Lee, Gwang-Seop;Lee, Jin-Young;Kim, Sung-Don;Kim, Joon-Soo
    • Resources Recycling
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    • v.14 no.2
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    • pp.33-42
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    • 2005
  • Solvent extraction experiments have been performed to separate Nd and Sm from chloride solution with PC88A. The effect of the saponification of PC88A on the extraction and separation of the two metals were studied. In the experimental ranges conducted in this study, the distribution coefficients of Sm were higher than those of Nd and separation factor between them increased with the equilibrium pH of aqueous solution. Saponification of PC88A enhanced the distribution coefficients of Sm and Nd and the separation factor. A chemical model was developed to predict the distribution coefficients of metals and separation factor from the initial extraction conditions. The measured distribution coefficients of Nd and Sm with PC88A and saponified PC88A agreed well with those calculated in this study.

Large Eddy Simulation of Flow around a Bluff Body of Vehicle Shape

  • Jang, Dong-Sik;Lee, Yeon-Won;Doh, Deug-Hee;Toshio Kobayashi;Kang, Chang-Soo
    • Journal of Mechanical Science and Technology
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    • v.15 no.12
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    • pp.1835-1844
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    • 2001
  • The turbulent flow with wake, reattachment and recirculation is a very important problem that is related to vehicle dynamics and aerodynamics. The Smagorinsky Model (SM), the Dynamics Subgrid Scale Model (DSM), and the Lagrangian Dynamic Subgrid Scale Model (LDSM) are used to predict the three-dimensional flow field around a bluff body model. The Reynolds number used is 45,000 based on the bulk velocity and the height of the bluff body. The fully developed turbulent flow, which is generated by the driver part, is used for the inlet boundary condition. The Convective boundary condition is imposed on the outlet boundary condition, and the Spalding wall function is used for the wall boundary condition. We compare the results of each model with the results of the PIV measurement. First of all, the LES predicts flow behavior better than the k-$\xi$ turbulence model. When ew compare various LES models, the DSM and the LDSM agree with the PIV experimental data better than the SM in the complex flow, with the separation and the reattachment at the upper front part of th bluff body. But in the rear part of the bluff body, the SM agrees with the PIV experimental results better than them. In this case, the SM predicts overall flow behavior better than the DSM nd the LDSM.

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An NSIS based Resource Reservation Protocol for Hose model VPN Service (Hose 모델 VPN 서비스를 위한 NSIS 기반 자원 예약 프로토콜)

  • Byun, Hae-Sun;Lee, Mee-Jeong
    • The KIPS Transactions:PartC
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    • v.14C no.7
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    • pp.559-570
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    • 2007
  • In this paper, we define a Hose-NSIS-QoSM, which reserves and manages resources according to the hose based resource provisioning mechanisms for supporting the VPN QoS(Quality of Service) using the NSIS(Next Step in Signaling) signaling protocol. Specifically, we specify the NSIS message objects, the structures of QoS NSLP(NSIS Signaling Layer Protocol)/NTLP(NSIS Transport Layer Protocol)/RMF(Resource Management Function) state tables and the processing of the signaling messages in NSIS nodes. Also, we compare the Hose-NSIS-QoSM with the Hose-RSVP-TE-QoSM that supports the hose based VPN QoS in the MPLS networks using the extended RSVP-TE mechanism.

Penetration Strategies of SM Entertainment in Global Market (SM 엔터테인먼트의 글로벌 시장 진출 특성)

  • Lee, Moon Haeng
    • Journal of Information Technology Services
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    • v.13 no.3
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    • pp.77-92
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    • 2014
  • Korean entertainment companies like SM entertainment, YG and JYP contribute enormously to the recent K-pop fever. They expand their businesses aggressively to foreign markets which has been successful. This paper seeks to find out their precise strategies to succeed in the global market. Our study focus on SM entertainment which manages successively in the Asian market. As a result, one of their successful strategies on the global market is localization. They rearrange a group with in the members to suit into the local market : for instance, Super Junior, representative boy group, has rearranged and reformed to Super Junior M (mandarin), Super Junior happy (for Japan market), etc. Coopration with SNS (Social Network Service) is another successful strategies of SM Entertainment : page views of K-pop on Youtube achieved more than 0.8 billion in 2013. Furthermore, for marketing, many members play an advertizing model for global products.

Design of Multimachine Stabilizer using Full-Order Observer-based SM-MF Controller including CLF : Part 5 (폐-루우프 피이드백을 가진 전-차수 관측기에 기준한 SM-MF 제어기를 이용한 다기 안정기 설계 : Part5)

  • Lee, Sang-Seung;Park, Jong-Keun
    • Proceedings of the KIEE Conference
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    • 1997.07c
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    • pp.1174-1176
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    • 1997
  • In this paper, the power system stabilizer(PSS) using the sliding mode observer-model following(SMO-MF) including closed-loop feedback(CLF) for single machine system is extended to multimachine system.

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