• Journal of Acupuncture Research
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• v.22 no.3
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• pp.113-122
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• 2005

Objective : The present study was carried out to investigate the preventive effect of Several Herb - Combined Prescription (SHP) on streptozotocin (STZ) - induced diabetes mellitus. Methods : SHP was given to mice with the combination of oral administration and herbal-acupuncture stimulation. Experimental diabetes was induced by the injection of STZ(50mg/kg) to the rat via the peritoneum The effect of SHP on STZ-induced diabetes was observed by measuring the serum level of insulin, glucose, triglyceride, total cholesterol and lipid peroxides. Hepatic activities of catalase and reduced glutathione were examined. Results : SHP treatment protected them from the hyperglycemia. STZ induced increase of serum triglyceride lowered by SHP treatment. Conclusions : The SHP treatment showed protective effect on diabetic mouse model, and action mechanism of the effect was thought to be concerned with anti-oxidative stress.

• International Journal of Fluid Machinery and Systems
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• v.8 no.1
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• pp.55-62
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• 2015

This study aims to present a hydraulic transitory study as MOC applications for solving the Saint-Venant equations in two case studies: 1) in a penstock of a small hydropower system as a simple pipeline in the case of valve-closure in the downstream boundary with a reservoir in the upstream boundary; and 2) for discharge propagation into a channel by velocity and depth of the flow channel along space evaluation. The proposed methodology by Chaudry [5] concerning the development of hydrodynamic models was used. The obtained results for first and second case study has been confirmed that MOC numerical approach is useful for several engineering purposes, including cases of hydraulic transients and discharge propagation in hydraulic systems.

• Molecules and Cells
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• v.38 no.5
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• pp.441-451
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• 2015

Recognition of cytosolic DNA initiates a series of innate immune responses by inducing IFN-I production and subsequent triggering JAK1-STAT1 signaling which plays critical roles in the pathogenesis of infection, inflammation and autoimmune diseases through promoting B cell activation and antibody responses. The stimulator of interferon genes protein (STING) has been demonstrated to be a critical hub of type I IFN induction in cytosolic DNA-sensing pathways. However, it still remains unknown whether cytosolic DNA can directly activate the JAK1-STAT1 signaling or not. And the role of STING is also unclear in this response. In the present study, we found that dsDNA directly triggered the JAK1-STAT1 signaling by inducing phosphorylation of the Lyn kinase. Moreover, this response is not dependent on type I IFN receptors. Interestingly, STING could inhibit dsDNA-triggered activation of JAK1-STAT1 signaling by inducing SHP-1 and SHP-2 phosphorylation. In addition, compared with normal B cells, the expression of STING was significantly lower and the phosphorylation level of JAK1 was significantly higher in B cells from MRL/lpr lupus-prone mice, highlighting the close association between STING low-expression and JAK1-STAT1 signaling activation in B cells in autoimmune diseases. Our data provide a molecular insight into the novel role of STING in dsDNA-mediated inflammatory disorders.

• Journal of Practical Agriculture & Fisheries Research
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• v.25 no.3
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• pp.14-18
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• 2023

White leg shrimps cultured in an inland private aquaculture farm with low salinity waters showed abnormal swimming behavior and appetite reduction in July 2022. Then, gradual mortality was observed in the aquaculture farm. During the diagnosis, bacterial strain KNUAF-SHP3 was isolated from the hepatopancreas of the dead shrimps. Based on the sequence of 16S rRNA gene, KNUAF-SHP3 was proved to be Shewanella sp., clustering into a group with S. algae MARS 14 and S. chilikensis JC5T. According to the result of experimental infection test, all shrimps challenged with high concentrations, 2.1×108 CFU/ml and 2.1×109 CFU/ml showed apparent disease symptoms and the cumulative mortality rates reached 100% in 7 days post challenge. These results emphasized that Shewanella isolate in this study can be a potential pathogen of white leg shrimp cultured in low salinity water.

• Korean Journal of Animal Reproduction
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• v.15 no.3
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• pp.189-193
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• 1991

This study was carried out ot investigate effects of X-537A on hydrogen ion concentration insperm washed solution and sperm acrosome reaction. The results obtained were as follows. 1. When bovine sperm was twice washed with SHP solutions of pH 6.8 and 7.4 and again washed with SHP solution containing 4$\mu$M of X-537A, in case of pH 6.8 the sperm washed with 4$\mu$M of X-537A showed signifciantly(p<0.01) higher hydrogen ion concentration in sperm washed solution than the sperm washed without X-537A. 2. When the sperm was twice washed with SHP solution and then washed with SHP solution containing 4$\mu$M of X-537A, sperm acrosome rection rate was signifciantly(p<0.01) increased from 12min after incubation in the sperm washed without X-537A, but was signifciantly(p<0.01) increased from 8 min after incubation in the sperm washed with 4$\mu$M of X-537A. 3. When the sperm was twice washed with SHP solution and then washed with SHP solution containing 0, 4 and 40$\mu$M of X-537A, and then incubated in m-TALP for 120 min, sperm acrosome reaction rate was significantly(p<0.01) increased from 15 min after incubation in 0, 4 and 40$\mu$m OF X-537A. However at 60 min incubation 40$\mu$M of X-537A showed significantly(p<0.01) higher sperm acrosome reaction rate than 0 and 4$\mu$M and at 120 min incubation 4 and 40$\mu$M of X-537A showed signifciantly(p<0.01) higher acrosome reaction rate than 0$\mu$M of X-537A.

• Tuberculosis and Respiratory Diseases
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• v.43 no.2
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• pp.280-284
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• 1996

We report the first case of summer-type hypersensitivity pneumonitis(SHP) in Korea diagnosed by positive serum antibodies to Trichosporon cutaneum. Hypersensitivity pneumonitis(HP) has been commonly classified as an occupational respiratory diseases. However, evidence that sensitizing organisms can also contaminate and cause pulmonary diseases in home environment has been increasing. One such disease is SHP. In Japan, 75% of cases with HP are SHP. Even though there has been no known SHP case in Korea yet, there has been high possibility of SHPs in Korea because our country has areas which have hot and humid summer climate similar to Japan. This first case of SHP in Korea suggests that there may be another cases in Korea and nation-wide survey may be required. We report here the first confirmed case of SHP in Korea.

• Journal of muscle and joint health
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• v.9 no.1
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• pp.5-17
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• 2002

The purpose of this one group pre and post test study was to evaluate the effect of self-help programs(SHP) which has been conducted from 1997 to 2000. The SHP was held by Korean Rheumatology Health Professionals Society(KRHP) once a week for 6 weeks for chronic arthritis patients in Korea. Eight hundred fifty five subjects completed the program at 43 sites. The effect of SHP were evaluated by flexibility, pain, activities of daily living(ADL), fatigue, depression and self-efficacy. After SHP, followings were found: 1. Participants' characteristics of SHP were most common in living in Seoul, women, sixties, high school graduates, house wifes, osteoarthritis, completed in 1999. 2. The flexibility of arm, knee, ankle joint were significantly increased, but the flexibility of the shoulder was not changed. 3. Level of pain was decreased significantly from 5.21 to 3.99, and the number of painful joints were decreased from 4.96 to 4.18 significantly. 4. The score of ADL was increased from 53.74 to 54.97 significantly. 5. The score of depression and self-efficacy was not changed. In conclusion, SHP was clearly proved to be an effective nursing intervention to Increase the flexibility of arm, knee, ankle joint and enhanced ADL. Also SHP decreased pain and fatigue. More research is needed to determine the role of self-efficacy and depression in the SHP, use of a randomized design and longer follow up period to understand more about the effects of the program.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.3
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• pp.143-166
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• 2008

Purpose: The purpose of this study is to ascertain the awareness or incidence of SHP and postnatal care. Methods: We analyzed the results of Questionnaires for 104 women who have experienced childbirth within the last 10 years and examined June 2007 to December 2007. We divided to three groups according to age and investigated. Results: 1. Awareness of SHP and postnatal care. Responses about "How informed are you about the syndrome known in Korea as SHP?", Person's ration who know is 72.11%. Responses about "Are you aware of current traditional postnatal practices in Korea?", Person's ration who know is 80.77%. "Do you think that postnatal care as practised is Korea is necessary?", Person's ration who know is 84.62%. "Do you think that in general postnatal care is necessary?", Person's ration who know is 93.27%. "Do you believe, if you are unable to practice postnatal care, you will subsequently develop health problems?", Person's ration who know is 91.35%. 2. Relevant comments of postnatal care. Responses about lifestyle after childbirth are Prevent bodily hard work 35.37%, Prevent cold stimulus 27.21 %, Hold body warmly 17.69%, Psychologically comfortably 7.48%, Eat good food 7.48% Etc 10.88%. Foods after childbirth are Avoid cold foods 22.38%, Avoid hard foods 17.48%, avoid hot foods 16.78%, avoid salty foods 10.49%, avoid excitative foods 8.39%. Medication after childbirth are Oriental medicine and restorative medicine 21.24%, iron was 15.04%, pumpkin 15.04%, vitamin 9.73%, calcium and snakehead each 7.96%. 3. Postnatal care practices Correlation postnatal care practices with present health condition are 19 items of 31 items. Conculsion: We hope these results could be helpful to diagnosis and treatment of SHP.

• Journal of Microbiology
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• v.38 no.3
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• pp.183-186
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• 2000

Several types of bioluminescent reporter strains have been developed for the detection and monitoring of pollutant aromatics contaminating the environment. In this study, a bioluminescent reporter strain, E. coli SHP3, was constructed by fusing the luc gene of firefly luciferase with the promoter of pcbC responsible for the meta-cleavage of aromatic hydrocarbons. the bioluminescence expressed by the luc gene in the reporter was well triggered by the promoter when it was exposed to 2,3-dihydroxybiphenyI (2,3-DHBP) at 0.5 to 1 mM concentrations. The bioluminescent response was more extensive when the reporter strain was exposed to 5 mM catechol and 2 mM 4-chlorocatechol. These different types of bioluminescent responses by E. coli SHP3 appeared to be characterized by the nature of the aromatics to stress. Since E. coli SHP3 responded to 2,3-DHBP quite sensitively, this reporter strain could be applied for detecting some catecholic pollutants.

• Journal of Sericultural and Entomological Science
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• v.36 no.1
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• pp.37-43
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• 1994

The effects of some sodium phosphates as auxiliary agents were studied on the blockade of hardness for silk degumming. In this work, four kinds of sodium phosphates were tested and the results were obtained through masking effects of metallic ions, difference of pH value and boil-off ratio. The degumming of calcium ingredient was analyzed by means of atomic absorption spectrophotometer and degumming test of cocoon shell was performed in the presence of calcium ingredient and sodium phosphates added to soap solution. In the view of the effects of sodium phosphates on calcium hardness, tetrasodium pyrophosphate(TSPP) and sodium phosphate dibasic(SPD) masked calcium ions more than sodium phosphate monobasic(SPM) and sodium hexametaphosphate(SHP). SHP and TSPP have excellent abilities of masking ferrous ions. The pH values of TSPP solution is higher than others, but lower than soap solution. The pH values were differently measured one another among the sodium phosphates but the boil-off ratio was increased in case of sodium phosphate with high pH value.