• Title/Summary/Keyword: SEB

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Comparative Measurement of Transverse Nuclear Magnetization of Polarized 129Xe and 131Xe by Spin-exchange Optical Pumping

  • Yu, Ye Jin;Min, Seong Ho;Moon, Han Seb
    • Current Optics and Photonics
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    • v.4 no.6
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    • pp.466-471
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    • 2020
  • We analyze the transverse nuclear magnetizations of 129Xe and 131Xe in a vapor cell containing natural Xe, 87Rb, and buffer gases. Th e Xe atoms are polarized th rough spin-exch ange optical pumping (SEOP) with Rb atoms under low-magnetic-field conditions. From the free-induction-decay (FID) signal, we measure the nuclear magnetization of the Xe atoms in the Xe-Rb vapor cell. Furthermore, we measure the dependence of the gyromagnetic ratio on the magnetization of 129Xe and 131Xe by examining the amplitude of the FID signal of each isotope, and we evaluate the relationship between the magnetic field gradient and transverse relaxation rate for both of the 129Xe and 131Xe isotopes.

Simulation of Leggett-Garg Inequalities Using a Heralded-single-photon Source (예고된 단일 광자 광원을 이용한 레겟-가르그 부등식 모사)

  • Kim, Su Hyun;Moon, Han Seb
    • Korean Journal of Optics and Photonics
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    • v.32 no.1
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    • pp.29-33
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    • 2021
  • We have experimentally simulated the violation of the Leggett-Garg inequality (LGI) using a heralded-single-photon source via spontaneous parametric down-conversion (SPDC) in a periodically poled potassium titanyl phosphate (PPKTP) crystal. We measured the polarization fringe as a function of the angle of the linear polarization of the photons, and analyzed the LGI according to n measurement. Simulation results for LGI based on the polarization of the heralded single photon were in good agreement with theoretical calculations.

Preliminary Optical and Opto-mechanical Design of Solar Telescope on Super Eye Bridge Program

  • Kim, Yunjong;Kim, Jihun;Moon, Il Kweon;Yoo, Jaegun;Jun, Youra;Choi, Seonghwan;Han, Jeong-Yeol;Jeong, Kwanghui
    • The Bulletin of The Korean Astronomical Society
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    • v.46 no.1
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    • pp.58.3-58.3
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    • 2021
  • 극한환경에서 작동 가능한 고분해능, 고정밀 대형 광학계 관측 플랫폼 시제품 (Super Eye Bridge) 인 태양 망원경 개발을 위한 광학 및 광기계 설계를 수행하였다. 차폐가 없으며 고속 팁-틸트 기능을 부여하여 이미지를 보정하고, 태양열로 인한 열적 성능저하를 방지하는 가능을 구현할 수 있도록 광학설계를 진행하였다. 광기계 설계는 극한 환경에 적용이 가능한 반사경의 경량화 및 지지 구조의 최적화를 진행하였으며 제작성을 고려한 SiC 신소재를 사용하고, 정렬을 위한 부반사경 조절부를 채용하였다. 본 연구에서는 SEB 태양망원경의 광학 및 광기계 설계 결과를 발표할 것이다.

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Analysis of Molecular Epidemiological Properties of Staphylococcus aureus Isolates from Domestic Animals and Human Patients by PCR (Polymerase Chain Reaction을 활용한 국내 동물과 사람환자에서 분리한 Staphylococcus aureus 분리주의 분자역학적 특성분석)

  • Woo Yong-Ku;Kim Shin
    • Korean Journal of Microbiology
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    • v.41 no.1
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    • pp.24-37
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    • 2005
  • This study was conducted to analyze the molecular epidemiological properties and to select the most efficient and reliable PCR method on 116 of Staphylococcus aureus (S. aureus) isolates from Korean cattle, black goat, pig, dog, chicken, mouse and also human clinical cases from hospital. The distribution patterns of SSG [species specific genes; coagulase (coa), protein A (spa), nuclease (nuc) and aroA (RsaI) gene] were analyzed by PCR method. Among the SSGs, the nuc-gene was found in all strains $(100\%)$ tested and followed by coa-gene $(87.9\%)$, spa-gene $(91.4\%)$ and aroA-gene $(26.7\%)$, in order. The genetic subtyping by RFLP method was performed on the coa [AluI] and aroA-gene [RsaI] PCR products. The mecA-gene PCR and PCR-RFLP techniques were chosen to detect and verify of MRSA strains. Only the human strains $(12.1\%)$ were detected the positive mecA-gene products (533 bp), which were divided into two specific bands [201 & 332 bp] by HhaI enzyme digestion. On coa-gene and spa-gene typing, coa-gene was typed with ten kinds of genotype and coa-3 type were determined as the most predominant genotype, while spa-gene was divided into eleven kinds of genotype and also spa-7 type were selected the most prevalent genotype based on their genetic variations. On the aroA and coa-gene subtyping by PCR-RFLP, aroA-gene products were discriminated with only seven types of genotype, while coa-gene products were further divided into an eleven genotype, respectively. In comparison of SID values of five PCR based typing methods, the coa-PCR-RFLP (SID0.894) was evaluated the most efficient and reliable tools and followed by coa-PCR (SID0.883) and aroA-PCR-RFLP (SID0.462), in order. In conclusion, we could determined that the coa-PCR-RFLP method was the most suitable genetic analysis tool for S. aureus and MRSA strains from domestic animals and humans.

Profiles of Enterotoxin Genes and Antimicrobial Resistance in Staphylococcus pseudintermedius Strains Isolated from Livestock and Companion Animals

  • Lee, Gi Yong;Lee, Haeng Ho;Um, Hong Sik;Yang, Soo-Jin
    • Journal of Food Hygiene and Safety
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    • v.34 no.6
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    • pp.576-582
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    • 2019
  • Staphylococcus pseudintermedius is an opportunistic pathogen in dogs and is recognized as a zoonotic pathogen causing public health concern. Although canine-associated S. pseudintermedius has mainly been recognized for its antimicrobial resistance and ability to cause skin infections in dogs, information on antimicrobial resistance profiles and enterotoxigenicity of S. pseudintermedius in livestock is very limited. In this study, we investigated the prevalence of 18 different staphylococcal enterotoxin (SE) genes and toxic shock syndrome toxin gene (tst-1) in S. pseudintermedius strains isolated from dogs, pigs, and beef cattle. Moreover, antimicrobial resistance profiles of the strains were determined along with the presence of mecA and SCCmec types. Except for one bovine isolate, all S. pseudintermedius isolates from dogs and pigs were resistant to multiple drugs (≥ 4 different drugs). Four out of six canine isolates were methicillin resistant and carried SCCmec type V. In addition, 11 different SE genes (seb, sec, see, seg, sei, sej, sel, seo, sep, seq, and seu) and tst-1 were identified in S. pseudintermedius isolates from dogs, pigs, and beef cattle. Most S. pseudintermedius isolates (83%) harbored multiple SE genes, and sel (42%) and sep (42%) were most frequently detected in the isolates. Our results suggested that S. pseudintermedius isolates from livestock and companion animals may serve as a reservoir for SE genes and antimicrobial resistance.

Screening of Staphylococcus aureus and Staphylococcal Enterotoxin a, b, c gene in Strains Isolated from Strawberry Farms in Western Gyeongnam (서부 경남지역 딸기 농장에서의 Staphylococcus aureus의 분리와 Staphylococcal enterotoxin a, b, c gene 검색)

  • Kim, Se-Ri;Shim, Won-Bo;Kim, Ji-Hun;Hwang, Seung-Jae;Park, Seon-Ja;Ha, Sang-Do;Kim, Keun-Sung;Lee, Kyu-Ho;Kim, Min-Gon;Kim, Kwang-Yup;Kim, Cheol-Ho;Chung, Duck-Hwa
    • Korean Journal of Food Science and Technology
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    • v.37 no.2
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    • pp.321-327
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    • 2005
  • Staphylococcus aureus is spread worldwide and can result in food poisoning outbreaks. Among samples collected from soil, water, protected houses, packing houses, employees, strawberries, and leaves, and analyzed for S. aureus contamination, 16% samples 'showed S. aureus contamination, particularly on employees' hands, scissors, and strawberries. Examination of enterotoxins A, B, and C genes of S. aureus by PCR revealed sea and seb in 92 and 38% of total strains, respectively, whereas sec was not detected. In conclusion, implementation of Good Agricultural Practice is necessary for preventing food-borne diseases of staphylococcal origin, thereby ensuring the safety of farm-to-table products.

Cannabidiol Inhibits Lipogenesis by Regulating Akt/AMPK-SREBP-1 Pathway in Sebocytes (피지세포에서 Akt/AMPK-SREBP-1 경로를 통한 CBD의 피지 합성 억제 효능)

  • Yoon Gyung Kwon;Ji Young Yoon;Hanon Lee;Dong Hyo Kim;Jun Hyo Lee;Diane M Thiboutot;Dae Hun Suh;Byoung Jun Park
    • Journal of Life Science
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    • v.33 no.4
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    • pp.343-348
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    • 2023
  • Acne is one of the most common skin diseases, mainly occurring in adolescence. The pathophysiology of acne involves not only hormonal, genetic and environmental factors, but also other factors including hyperseborrhea, inflammation, over-keratinization of follicular keratinocytes and overgrowth of Cutibacterium acnes (C. acnes). Cannabidiol (CBD) is known to relieve pain, stress and inflammation. Moreover, cannabis extracts containing CBD have been reported to be effective in treating acne. However, the therapeutic effect of CBD on acne remains unclear. Therefore, this study aimed to investigate the effect and mechanism of CBD on lipogenesis in SEB-1 sebocytes. We treated sebocytes with CBD and found that it not only inhibited lipid synthesis, but also inhibited cell proliferation by inducing apoptosis. We then demonstrated that sterol response element-binding protein-1 (SREBP-1) mediates the inhibitory effect of CBD on lipogenesis. Furthermore, Akt and adenosine monophosphate-activated protein kinase (AMPK), upstream regulators of SREBP-1, were regulated by CBD treatment. Taken together, our studies demonstrate that CBD inhibits adipogenesis by regulating the Akt/AMPK-SREBP-1 signaling pathway, providing potential for use as a therapeutic agent for acne. Further research is needed to confirm the effect of CBD on inflammation caused by hyperkeratosis, which will increase the possibility of using CBD for acne treatment.

A Feasibility Assessment of CMDS (Coal Mine Drainage Sludge) in the Stabilization of Mercury Contaminated Soil in Mine Area (광산지역 수은 오염토양 안정화를 위한 석탄광산배수슬러지의 적용성 평가)

  • Koh, Il-Ha;Kwon, Yo Seb;Moon, Deok Hyun;Ko, Ju In;Ji, Won Hyun
    • Journal of Soil and Groundwater Environment
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    • v.25 no.1
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    • pp.53-61
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    • 2020
  • This study assessed the feasibility of coal mine drainage sludge (CMDS) as a stabilizing agent for mercury contaminated soil through pot experiments and batch tests. In the pot experiments with 43 days of lettuce growth, the bioavailability of mercury in the amended soil and mercury content of the lettuce were decreased by 46% and 50%, respectively. These results were similar to those of the soil amended with the sulfide compound (FeS) generally used for mercury stabilization. Thus, CMDS could be an attractive mercury stabilizer in terms of industrial by-product recycling. Batch tests were conducted to examine mercury fractionation including reactions between the soil and acetic acid. The result showed that some elemental fraction changed to strongly bounded fraction rather than residual (HgS) fraction. This made it possible to conclude that mercury adsorption on oxides in CMDS was the major mechanism of stabilization.

A Case of Lung Cancer associated with von Recklinghausen's Disease (Von Recklinghausen 병에 동반된 폐암 1예)

  • Han, Yo-Seb;Kang, Hong-Mo;Han, Min-Soo;Yoo, Jee-Hong
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.3
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    • pp.604-608
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    • 1998
  • Von Recklinghausen's disease is an autosomal dominant hereditary disease associated with characteristic cafe-au-lait spots of skin and multiple neurofibromatosis. It is complicated by malignancies, which in most cases is neurofibrosarcoma. The development of lung cancer in von Recklinghausen's disease is rare. A 61-year-old male was admitted for cough and sputum for 20 days. He had multiple cafe-au-lait spots and subcutaneous neurofibromas in whole body area and Lisch nodules in both iris and he had been diagnosed von Recklinghausen's disease 35 years ago. Chest radiography showed emphysematous bullae in both upper lung field and mass in right upper lung field. Chest CT scan revealed subcarinal lymph node enlargement. Bronchoscopic biopsy was done in mass in superior segment of right lower lobe and the results showed squamous cell carcinoma. The presence of von Recklinghausen's disease and lung cancer are noteworthy.

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A Design of Over-driving Controller to Reduce Motion Blur (Motion Blur를 줄이기 위한 Over-driving Controller 설계)

  • Nam, Ki-Hun;Shin, Yong-Seb
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.47 no.4
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    • pp.1-6
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    • 2010
  • We can see the motion blur phenomenon on theedge of the moving picture when it moves in the LCDs. To reduce this phenomenon, we suggested a new over-deriving method, implemented on the board XUP Virtex-2 Pro Development System by using Virtex-2 Pro XUP XC2VP30 and improved the Motion Blur. In this method, we did not use additional parts except for a SDRAM. Hardware implementation for IP and data interface were handled in software. In this paper, we used the moving bar and the moving video image as a design model. We also showed that the afterimage was reduced and the vivid moving images was displayed. through this method.