• Title/Summary/Keyword: SBF:

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Inhibition of Osteoclast differentiation based on precipitation time of titanium surfaces immersed in modified simulated body fluid (Modified simulated body fluid에 침전한 티타늄 표면에서 침전 기간에 따라 나타나는 파골 세포의 분화억제 양상)

  • Chang, Hyun-min;Heo, Seong-Joo;Kim, Seong-Kyun;Koak, Jai-Young
    • The Journal of Korean Academy of Prosthodontics
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    • v.57 no.2
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    • pp.142-149
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    • 2019
  • Purpose: The purpose of this study is to investigate the changes of osteoclast differentiation inhibition according to the period of precipitation when titanium disks were immersed in Modified simulated body fluid (mSBF). Materials and methods: Titanium alloy (Ti grade III) disks with machined surfaces and anodized surfaces were immersed in distilled water and mSBF, respectively. The immersion periods were 7 days, 14 days, 21 days and 28 days, and the control group was immersed in distilled water for each period. RAW 264.7 cells capable of differentiating into osteoclasts were used to measure the number of adherent cells, the measurement of TRAP activity, and the expression pattern of NFATc1 by western blotting. Results: The degree of inhibition of osteoclast differentiation was found to be statistically significant when the disks were immersed in mSBF for more than 14 days on both machined surfaces and anodized surfaces. There was no correlation between immersion time and cell attachment. When the disks were immersed for more than 14 days, TRAP activity was decreased and NFATc1 expression was inhibited. Futhermore, the decrease in TRAP activity and the inhibition of NFATc1 expression remained unchanged. Conclusion: Immersion of titanium disks in mSBF for more than 14 days can prevent RAW 264.7 cells from differentiating into osteoclasts. Inhibition activity does not change even if the immersion period is for more than 14 days.

Conceptual Core Design of 1300MWe Reactor for Soluble Boron Free Operation Using a New Fuel Concept

  • Kim, Soon-Young;Kim, Jong-Kyung
    • Nuclear Engineering and Technology
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    • v.31 no.4
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    • pp.391-400
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    • 1999
  • A conceptual core design of the 1,300MWe KNGR (Korean Next Generation Reactor) without using soluble boron for reactivity control was developed to determine whether it is technically feasible to implement SBF (Soluble Boron Free) operation. Based on the borated KNGR core design, the fuel assembly and control rod configuration were modified for extensive use of burnable poison rods and control rods. A new fuel rod, in which Pu-238 had been substituted for a small amount of U-238 in fuel composition, was introduced to assist the reactivity control by burnable poison rods. Since Pu-238 has a considerably large thermal neutron capture cross section, the new fuel assembly showed good reactivity suppression capability throughout the entire cycle turnup, especially at BOC (Beginning of Cycle). Moreover, relatively uniform control of power distribution was possible since the new fuel assemblies were loaded throughout the core. In this study, core excess reactivity was limited to 2.0 %$\delta$$\rho$ for the minimal use of control rods. The analysis results of the SBF KNGR core showed that axial power distribution control can be achieved by using the simplest zoning scheme of the fuel assembly Furthermore, the sufficient shutdown margin and the stability against axial xenon oscillations were secured in this SBF core. It is, therefore, concluded that a SBF operation is technically feasible for a large sized LWR (Light Water Reactor).

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Sensitivity analysis of self-centering rocking steel braced frames to far-field and near-field earthquakes

  • Masoomeh Naraghi;S. Mohammad Mirhosseini;Hossein Rahami;Abdolreza S. Moghadam
    • Steel and Composite Structures
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    • v.53 no.2
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    • pp.155-167
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    • 2024
  • Identifying the location of earthquake-induced damage in buildings and mitigating its impact, especially in low-damage systems such as rocking frames, is a significant challenge for structural engineers. Therefore, it is crucial to investigate the sensitivity and type of damage of buildings exposed to severe earthquakes to concentrate damage in predefined locations that can be repaired easily. This paper explores the seismic responses of a Self-Centering Rocking Steel Braced Frame (SCR-SBF) under far-field and near-field ground motions. This earthquake-resistant system includes components such as post-tensioning cables to provide frame self-centering, eliminate residual drift in the system, and replaceable fuses to concentrate the earthquake-induced damage. While previous studies have examined far and near-field earthquakes, their comparative influence on the seismic behavior of structures with a rocking system remains unexplored. This paper presents a novel investigation into the sensitivity of SCR-SBF structures to far and near-field earthquakes. Considering the critical effects of shock and impulse loads on rocking systems, the study aims to assess the effects of near-field earthquakes and compare them to far-field earthquakes on these systems. For this purpose, different response parameters have been calculated under records of far- and near-field earthquakes at three specific ground acceleration levels by incremental nonlinear dynamic analysis. Additionally, the seismic behavior of the SCR-SBF and Steel-Braced Frame (SBF) are compared for near and far-field ground motions. The results show that SCR-SBF systems have better resilience and reduced local failures compared to SBF systems under far and near-field earthquakes, requiring tailored design strategies.

Improved Simple Boundary Following Algorithm (개선된 간단한 경계선 추적자 알고리즘)

  • Cheong, Cheol-Ho;Han, Tack-Don
    • Journal of KIISE:Software and Applications
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    • v.33 no.4
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    • pp.427-439
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    • 2006
  • The SBF (Simple Boundary Follower) is a boundary-following algorithm, and is used mainly for image recognition and presentation. The SBF is very popular because of its simplicity and efficiency in tracing the boundary of an object from an acquired binary image; however, it does have two drawbacks. First, the SBF cannot consistently process inner or inner-outer corners according to the follower's position and direction. Second, the SBF requires movement operations for the non-boundary pixels that are connected to boundary pixels. The MSBF (Modified Simple Boundary Follower) has a diagonal detour step for preventing inner-outer corner inconsistency, but is still inconsistent with inner-corners and still requires extra movement operations on non-boundary pixels. In this paper, we propose the ISBF (Improved Simple Boundary Follower), which solves the inconsistencies and reduces the extra operations. In addition, we have classified the tour maps by paths from a current boundary pixel to the next boundary pixel and have analyzed SBF, MSBF, and ISBF. We have determined that the ISBF has no inconsistency issues and reduces the overall number of operations.

Biomimetic Apatite Precipitated on the Surface of Titanium Powder (티타늄분말의 표면에 석출된 생체모방 아파타이트)

  • Kim, Jong-Hee;Sim, Young-Uk;Yang, Tae-Young;Yoon, Seog-Young;Park, Hong-Chae
    • Journal of the Korean Ceramic Society
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    • v.47 no.2
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    • pp.127-131
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    • 2010
  • Biomimetic whisker-like apatite was formed on thermally and NaOH-treated titanium powder in a simulated body fluid (SBF). In the early process of the SBF immersion, the surface structure of the titanium powder was loosened, possibly due to the dissolution of $Na^+$ ions on the surface of the titanium powder into SBF. When immersed for 7 days in SBF, fine precipitates appeared on the titanium surfaces; the coating layer (<200 nm in thickness) consisted of nanostructured, amorphous whisker-like and particulate phase, observed by TEM. With the extension of the immersion time to 16 days, the chrysanthemum flower type morphology of carbonated hydroxyapatite with a nanocrystallinity was developed on the surface of the titanium powder.

An advanced core design for a soluble-boron-free small modular reactor ATOM with centrally-shielded burnable absorber

  • Nguyen, Xuan Ha;Kim, ChiHyung;Kim, Yonghee
    • Nuclear Engineering and Technology
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    • v.51 no.2
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    • pp.369-376
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    • 2019
  • A complete solution for a soluble-boron-free (SBF) small modular reactor (SMR) is pursued with a new burnable absorber concept, namely centrally-shielded burnable absorber (CSBA). Neutronic flexibility of the CSBA design has been discussed with fuel assembly (FA) analyses. Major design parameters and goals of the SBF SMR are discussed in view of the reactor core design and three CSBA designs are introduced to achieve both a very low burnup reactivity swing (BRS) and minimal residual reactivity of the CSBA. It is demonstrated that the core achieves a long cycle length (~37 months) and high burnup (~30 GWd/tU), while the BRS is only about 1100 pcm and the radial power distribution is rather flat. This research also introduces a supplementary reactivity control mechanism using stainless steel as mechanical shim (MS) rod to obtain the criticality during normal operation. A further analysis is performed to investigate the local power peaking of the CSBA-loaded FA at MS-rodded condition. Moreover, a simple $B_4C$-based control rod arrangement is proposed to assure a sufficient shutdown margin even at the cold-zero-power condition. All calculations in this neutronic-thermal hydraulic coupled investigation of the 3D SBF SMR core are completed by a two-step Monte Carlo-diffusion hybrid methodology.

Zinc status and growth of Korean infants fed human milk, casein-based, or soy-based formula: three-year longitudinal study

  • Han, Young-Hee;Yon, Mi-Yong;Han, Heon-Seok;Johnston, Kelley E.;Tamura, Tsunenobu;Hyun, Tai-Sun
    • Nutrition Research and Practice
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    • v.5 no.1
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    • pp.46-51
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    • 2011
  • To evaluate the effect of feeding methods on growth and zinc nutritional status of infants early in life, we monitored from birth to 36 months in 51 infants who were exclusively fed human milk (HM, n=20), casein-based formula (CBF, n=12), or soy-based formula (SBF, n=19) during the first five months of life. Zinc status was assessed by analyzing serum zinc concentrations and zinc intakes. Zinc contents in HM and formulas were measured. Zinc intake was estimated by weighing infants before and after feeding in the HM group and by collecting formula-intake records in the CBF and SBF groups. After solid foods were introduced, all foods consumed were also included to estimate zinc intake. The growth of infants in all groups was similar to that established for normal Korean infants. Human milk zinc concentrations declined as lactation progressed. Zinc concentrations in all formulas tested in this study were higher than HM and were also higher than those claimed by the manufacturers. During the first twelve months, mean serum zinc concentrations of infants were similar in all groups, although infants in the HM group consistently had the lowest zinc intake among the groups, and the overall zinc intake in infants fed SBF was highest. This finding could be explained by the difference zinc bioavailability of HM and formulas. In conclusion, infants fed HM, CBF or SBF has normal growth up to three years of age, although HM contained the lowest zinc concentration followed by CBF, then SBF.

Degradation Behavior of Hydroxyapatite with Different Crystallinity in Simulated Body Fluid Solution (의사체액에서 수산화아파타이트의 결정성에 따른 분해거동)

  • Jin, Hyeong-Ho;Kim, Dong-Hyun;Kim, Tae-Wan;Park, Hong-Chae;Yoon, Seog-Young
    • Korean Journal of Materials Research
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    • v.21 no.6
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    • pp.347-351
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    • 2011
  • Hydroxyapatite (HAp) powders with different crystallinities were synthesized at various calcination temperatures through the co-precipitation of $Ca(OH)_2$ and $H_3PO_4$. The degradation behavior of these HAp powders with different crystallinities was assessed in a simulated body fluid solution (SBF) for 8 weeks. Below $800^{\circ}C$, the powders were nonstochiometric HAp, and the single HAp phase was successfully synthesized at $800^{\circ}C$. The degree of crystallinity of the HAp powders increased with an increasing calcination temperature and varied in a range from 39.6% to 92.5%. In the low crystallinity HAp powders, the Ca and P ion concentrations of the SBF solution increased with an increasing soaking time, which indicated that the low crystallinity HAp degraded in the SBF solution. The mass of the HAp powders linearly decreased with respect to the soaking time, and the mass loss was higher at lower crystallinities. The mass loss ranged from 0.8% to 13.2% after 8 weeks. The crystallinity of the HAp powders increased with an increasing soaking time up to 4 weeks and then decreased because of HAp degradation. The pH of the SBF solution did not change much throughout the course of these experiments. These results suggested that the crystallinity of HAp can be used to control the degradation.

WEYL TYPE-THEOREMS FOR DIRECT SUMS

  • Berkani, Mohammed;Zariouh, Hassan
    • Bulletin of the Korean Mathematical Society
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    • v.49 no.5
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    • pp.1027-1040
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    • 2012
  • The aim of this paper is to study the Weyl type-theorems for the orthogonal direct sum $S{\oplus}T$, where S and T are bounded linear operators acting on a Banach space X. Among other results, we prove that if both T and S possesses property ($gb$) and if ${\Pi}(T){\subset}{\sigma}_a(S)$, ${\PI}(S){\subset}{\sigma}_a(T)$, then $S{\oplus}T$ possesses property ($gb$) if and only if ${\sigma}_{SBF^-_+}(S{\oplus}T)={\sigma}_{SBF^-_+}(S){\cup}{\sigma}_{SBF^-_+}(T)$. Moreover, we prove that if T and S both satisfies generalized Browder's theorem, then $S{\oplus}T$ satis es generalized Browder's theorem if and only if ${\sigma}_{BW}(S{\oplus}T)={\sigma}_{BW}(S){\cup}{\sigma}_{BW}(T)$.