• Journal of Pharmacopuncture
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• v.24 no.4
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• pp.165-172
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• 2021

The COVID-19, the most infectious pandemic disease arising due to SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) has caused huge issues globally. In this review, we discuss the impact of COVID-19 on the immune system of the human body and the protective mechanisms of the host immune system opposing viral infections. Here, we summarize the effect of the pandemic of the novel coronavirus disease on the immune system such as sleep and Behavioral Immune System (BIS) together with consideration of researcher's observation points of view. We draw particular attention to recent up-to-date reports concerning COVID-19 drugs as well as information about the landscape document for COVID-19 vaccines released by WHO (World Health Organization), and some adverse events of COVID-19 vaccination. Additionally, can take part in the preventive appraise in opposition within this pandemic severe COVID-19 infections disease may affect some outcome in physical exercise, physical movement, healthy diets, and good nutrition are significant for supporting the immune systems and summarize AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) Indian medicinal systems guidelines for immunity boosting procedures during COVID-19 pandemic.

• Journal of the Microelectronics and Packaging Society
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• v.29 no.1
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• pp.67-70
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• 2022

In the present work, we have designed to optimize the optical filter structures of the 1-dimensional photonic quasicrystals (1D PQCs) characteristic for the COVID-19 UV sterilization. The simulator using MATLAB program and ourselves manufacturing calculation codes. After making the aperiodic (and complexed) multi-layer structure model, we establish the transfer matrix method (TMM) for model by the operator conversion. By the using the MATLAB, we derive a matrix for the designed complexed multi-layer structure by applying the equations to the model by obtaining the reflectance and transmittance from the matrix. We also prove the possibility of application in optical filter for UV sterilization.

• Journal of Ginseng Research
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• v.46 no.3
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• pp.321-330
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• 2022

Coronavirus has been spreading rapidly around the world since it broke out in China in 2019. Respiratory diseases caused by coronavirus infection cause various diseases ranging from asymptomatic subclinical infections to severe pneumonia and cardiovascular complications, leading to death. In this regard, natural products are being studied to prevent various diseases caused by COVID-19. In current review, we would like to present mechanisms related to the inhibition of heart disease in ginseng and ginsenoside against SARS-CoV-2. In many previous studies, ginseng and ginsenoside are known to have antioxidant, blood flow improvement, improvement of vascular and heart function, blood pressure control, suppression of myocardial infarction and heart failure, and antiarrhythmia. Therefore, ginseng and ginsenoside have a possibility to suppress cardiovascular complications caused by COVID-19. Many of research provide evidence for ginseng and ginsenoside as treatments for the risk of cardiovascular complications. However, in this review, more specific contents on the proposition of the efficacy of ginseng and ginsenoside for COVID-19 should be presented. Therefore, we hope that researches to reduce cardiovascular complications of ginseng and ginsenoside for COVID-19 should be presented to reduce mortality for COVID-19.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.33 no.1
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• pp.54-57
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• 2022

The coronavirus disease (COVID-19) by severe acute syndrome coronavirus-2 (SARS-CoV-2) occurs the unprecedented pandemic during recent two years and the WHO declared a global pandemic of COVID-19 in March 2020. The most common sampling sites in COVID-19 test are the oropharynx and nasopharynx. We recently encountered a total laryngectomee who had a positivity COVID-19 diagnostic test from the tracheostoma, on the other hand, false negativity from the nasal cavity. The meaning of this case is that accurate screening test could be achieved by performing a test through the tracheostoma as well as nasal cavity or oropharynx. We also would like to discuss the accurate testing methods of patients whose airflow has distorted due to surgery, the management method of these patients, and the need of further research in the COVID-19 pandemic period with relevant literature reviews.

• Journal of Information Technology Services
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• v.20 no.5
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• pp.73-87
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• 2021

The COVID-19 pandemic has brought about many changes in our daily lives and in industries as a whole. The most notable change was the spread of the untact culture to minimize face-to-face contact. The spread of the untact culture has changed the use of public transportation. Looking at the results of previous SARS and MERS studies, it was found that as the pandemic spreads, the use of public transportation decreased. Recently, the mobility sharing service is attracting attention as a personalized means of transportation instead of public transportation. Therefore, in this study, the factors affecting the intention to use the mobility sharing service were to be identified by the actual users. In this study, economic benefit, convenience, sustainability, and sense of belonging were set as independent variables based on previous studies. In addition, the relationship between the perceived usefulness and perceived pleasure of these factors of use on intention to use was empirically analyzed through PLS-SEM. As a result of the study, it was found that economic benefits, convenience, sustainability, and sense of belongingness had a significant effect on intention to use through perceived usefulness and enjoyment. This study was meaningful in that it was verified through the study that economic benefits, convenience, sustainability, and a sense of belongingness were significant variables affecting the intention to use through usefulness and pleasure.

• Molecules and Cells
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• v.44 no.12
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• pp.861-878
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• 2021

The human genome contains many retroviral elements called human endogenous retroviruses (HERVs), resulting from the integration of retroviruses throughout evolution. HERVs once were considered inactive junk because they are not replication-competent, primarily localized in the heterochromatin, and silenced by methylation. But HERVs are now clearly shown to actively regulate gene expression in various physiological and pathological conditions such as developmental processes, immune regulation, cancers, autoimmune diseases, and neurological disorders. Recent studies report that HERVs are activated in patients suffering from coronavirus disease 2019 (COVID-19), the current pandemic caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection. In this review, we describe internal and external factors that influence HERV activities. We also present evidence showing the gene regulatory activity of HERV LTRs (long terminal repeats) in model organisms such as mice, rats, zebrafish, and invertebrate models of worms and flies. Finally, we discuss several molecular and cellular pathways involving various transcription factors and receptors, through which HERVs affect downstream cellular and physiological events such as epigenetic modifications, calcium influx, protein phosphorylation, and cytokine release. Understanding how HERVs participate in various physiological and pathological processes will help develop a strategy to generate effective therapeutic approaches targeting HERVs.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.6
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• pp.2018-2043
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• 2022

Nowadays, COVID-19 infections are influencing our daily lives which have spread globally. The major symptoms' of COVID-19 are dry cough, sore throat, and fever which in turn to critical complications like multi organs failure, acute respiratory distress syndrome, etc. Therefore, to hinder the spread of COVID-19, a Computerized Doughty Predictor Framework (CDPF) is developed to yield benefits in monitoring the progression of disease from Chest CT images which will reduce the mortality rates significantly. The proposed framework CDPF employs Convolutional Neural Network (CNN) as a feature extractor to extract the features from CT images. Subsequently, the extracted features are fed into the Adaptive Dragonfly Algorithm (ADA) to extract the most significant features which will smoothly drive the diagnosing of the COVID and Non-COVID cases with the support of Doughty Learners (DL). This paper uses the publicly available SARS-CoV-2 and Github COVID CT dataset which contains 2482 and 812 CT images with two class labels COVID⁺ and COVI^-. The performance of CDPF is evaluated against existing state of art approaches, which shows the superiority of CDPF with the diagnosis accuracy of about 99.76%.

• Safety and Health at Work
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• v.13 no.1
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• pp.104-111
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• 2022

Background: The IMPPAC cohort (Implications of the COVID-19 pandemic on psychosocial aspects and work ability among Brazilian workers) seeks to understand the impact of the pandemic on Brazilian workers. This article describes the occupational profile, psychosocial aspects, and work ability determined during the baseline and follow-up measurements of the cohort. Methods: Workers were invited to participate through media advertisements, social networks, and emails. From June to September 2020, 1211 workers were included in the cohort. Follow-up measurements finished on October 2021 with 633 workers. Data were collected through standardized questionnaires using Google Forms. Psychosocial aspects were assessed using the COPSOQ II-Br. Work ability was assessed using the Work Ability Index (WAI). Results: At baseline and follow-up, high proportion of workers were in the risk zone with regard to work pace, emotional work demands, influence on work, work-family conflict, burnout, and stress. Approximately 75% of the workers reported good to excellent work ability at baseline and follow-up. Conclusion: The occupational profile, psychosocial aspects, and work ability of Brazilian workers from the IMPPAC cohort were described. Psychosocial aspects and WAI were similar at baseline and follow-up.

• Pediatric Infection and Vaccine
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• v.29 no.1
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• pp.16-27
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• 2022

In Korea, children aged 5 to 11 have been vaccinated against coronavirus disease 2019 (COVID-19) from March 2022. Due to this age group not being at a high risk of developing severe COVID-19 symptoms, each major country has different, circumstance dependent, immunization policies for children. In this review, the COVID-19 vaccination policies for 5-11 years old children in major countries were reviewed and considerations were presented for Korea, where children 5-11 years old are starting to get vaccinated against COVID-19.

• Health Policy and Management
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• v.32 no.1
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• pp.45-52
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• 2022

Background: There are regional variations in the incidence of coronavirus disease 2019 (COVID-19), which means that some regions are more exposed to the risk of COVID-19 than others. Therefore, this study aims to investigate regional variations in the incidence of COVID-19 in Korea and identify risk factors associated with the incidence of COVID-19 using community-level data. Methods: This study was conducted at the districts (si·gun·gu) level in Korea. Data of COVID-19 incidence by districts were collected from the official website of each province. Data was also obtained from the Korean Statistical Information Service and the Community Health Survey; socio-demographic factor, transmission pathway, healthcare resource, and factor in response to COVID-19. Community risk factors that drive the incidence of COVID-19 were selected using a least absolute shrinkage and selection operator regression. Results: As of June 2021, the incidence of COVID-19 differed by more than 80 times between districts. Among the candidate factors, sex ratio, population aged 20-29, local financial independence, population density, diabetes prevalence, and failure to comply with the quarantine rules were significantly associated with COVID-19 incidence. Conclusion: This study suggests setting COVID-19 quarantine policy and allocating resources, considering the community risk factors. Protecting vulnerable groups should be a high priority for these policies.