• Title/Summary/Keyword: S1P

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A Study on the Relationship of [i] Sound Wave to Sasang Constitution - by Sasang Constitution Analysed with PSSC-2004 ([i]음성파형과 사상체질과의 상관성연구 - 사상체질음성분석기(四象體質音聲分析機)(PSSC-2004)를 이용하여)

  • Song, Hak-Soo;Jung, Woon-Ki;Choi, Min-Ki;Kim, Jong-Chae;Kim, Dal-Rae;Yoo, Jun-Sang
    • Journal of Sasang Constitutional Medicine
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    • v.18 no.2
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    • pp.68-82
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    • 2006
  • 1. Objectives and Methods The purpose of this study was to objectify the diagnosis of Sasang constitution. It was analyzed the adult men and women's [i] sound into 23 factors with PSSC-2004. The study was conducted by subjects inputting 2.5-3 sec of [i] of 586 adult men and women's voices to PSSC-2004. The statistical analysis are applied to three groups : total group, male group, female group. The group of total 586 was composed with 155 Soyangin, 230 Taeumin and 201 Soeumin. The male group was composed with 61 Soyangin, 127 Taeumin and 87 Soeumin. The female group was composed with 94 Soyangin, 103 Taeumin and 114 Soeumin. 2. Results (1) In total group, the Soyangin's code3 was significantly low compared with the others(P=0.011). In total group, the Taeumin's code2 and the Soyangin's code1 were significantly high compared with the others(p=0.007)(P=0.030). (2) In total group, the Soyangin's peak, 50 up in peak and under 3 in peak were significantly low compared with the others(P=0.003) (P=0.005)(P=0.023). (3) In total group, the Taeumin's rank7, rank8, rank9 and rank10 were significantly high compared with the others (P=0.013)(P=0.015) (P=0.016)(P=0.003). (4) In male group, the Soeumin's code3 was significantly high compared with the others(P=0.002). (5) In male group, the Soeumin's peak sum was significantly high compared with the others(P=0.009). It was significant for distinction between Soeumin and Soyangin at the result of post mortem. In male group, the Soeumin's 50 up in peak, 50 down in peak were significantly high compared with the others(P=0.049)(p=0.037). In male group, the Soeumin's under 3 in peak was significantly high compared with the others(P=0.016). It was significant for distinction between Soeumin and Soyangin at the result of post mortem. (6) In male group, the Soeumin's rank 2, rank 3 and rank 4 were significantly low compared with the others(P=0.011) (0.011)(0.024). (7) In female group, the Taeumin's code2 was significantly high compared with the others(P=0.023). In female group, the Soyangin's code1 was significantly low compared with the others (P=0.046). In female group, Soyangin's code-1 was significantly high compared with the others(P=0.024). It was significant for distinction between Taeumin and Soyangin at the result of post mortem. (8) In female group, the Taeumin's peak sum was significantly high compared with the others(P=0.024). It was significant for distinction between Taeumin and Soyangin at the result of post mortem. In female group, the Taeumin's 50 up in peak was significantly high compared with the others(P=0.012). (9) In female group, the Taeumin's rank 7, rank 8, rank 9 and rank 10 were significantly high compared with the others (P=0.009) (P=0.013)(P=0.016)(P=0.023). 3. Conclusion From above result, there is the possibility of efficiency standardguide for constitutional diagnosis by analyzation of the voices.

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Cyclic Phytosphingosine-1-Phosphate Primed Mesenchymal Stem Cells Ameliorate LPS-Induced Acute Lung Injury in Mice

  • Youngheon Park;Jimin Jang;Jooyeon Lee;Hyosin Baek;Jaehyun Park;Sang-Ryul Cha;Se Bi Lee;Sunghun Na;Jae-Woo Kwon;Seok-Ho Hong;Se-Ran Yang
    • International Journal of Stem Cells
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    • v.16 no.2
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    • pp.191-201
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    • 2023
  • Background and Objectives: O-cyclic phytosphingosine-1-phosphate (cP1P) is a synthetic chemical and has a structure like sphingosine-1-phosphate (S1P). S1P is known to promote cell migration, invasion, proliferation, and anti-apoptosis through hippocampal signals. However, S1P mediated cellular-, molecular mechanism is still remained in the lung. Acute lung injury (ALI) and its severe form acute respiratory distress syndrome (ARDS) are characterized by excessive immune response, increased vascular permeability, alveolar-peritoneal barrier collapse, and edema. In this study, we determined whether cP1P primed human dermal derived mesenchymal stem cells (hdMSCs) ameliorate lung injury and its therapeutic pathway in ALI mice. Methods and Results: cP1P treatment significantly stimulated MSC migration and invasion ability. In cytokine array, secretion of vascular-related factors was increased in cP1P primed hdMSCs (hdMSCcP1P), and cP1P treatment induced inhibition of Lats while increased phosphorylation of Yap. We next determined whether hdMSCcP1P reduce inflammatory response in LPS exposed mice. hdMSCcP1P further decreased infiltration of macrophage and neutrophil, and release of TNF-α, IL-1β, and IL-6 were reduced rather than naïve hdMSC treatment. In addition, phosphorylation of STAT1 and expression of iNOS were significantly decreased in the lungs of MSCcP1P treated mice. Conclusions: Taken together, these data suggest that cP1P treatment enhances hdMSC migration in regulation of Hippo signaling and MSCcP1P provide a therapeutic potential for ALI/ARDS treatment.

SOME EXTENSION RESULTS CONCERNING ANALYTIC AND MEROMORPHIC MULTIVALENT FUNCTIONS

  • Ebadian, Ali;Masih, Vali Soltani;Najafzadeh, Shahram
    • Bulletin of the Korean Mathematical Society
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    • v.56 no.4
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    • pp.911-927
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    • 2019
  • Let $\mathscr{B}^{{\eta},{\mu}}_{p,n}\;({\alpha});\;({\eta},{\mu}{\in}{\mathbb{R}},\;n,\;p{\in}{\mathbb{N}})$ denote all functions f class in the unit disk ${\mathbb{U}}$ as $f(z)=z^p+\sum_{k=n+p}^{\infty}a_kz^k$ which satisfy: $$\|\[{\frac{f^{\prime}(z)}{pz^{p-1}}}\]^{\eta}\;\[\frac{z^p}{f(z)}\]^{\mu}-1\| <1-{\frac{\alpha}{p}};\;(z{\in}{\mathbb{U}},\;0{\leq}{\alpha}<p)$$. And $\mathscr{M}^{{\eta},{\mu}}_{p,n}\;({\alpha})$ indicates all meromorphic functions h in the punctured unit disk $\mathbb{U}^*$ as $h(z)=z^{-p}+\sum_{k=n-p}^{\infty}b_kz^k$ which satisfy: $$\|\[{\frac{h^{\prime}(z)}{-pz^{-p-1}}}\]^{\eta}\;\[\frac{1}{z^ph(z)}\]^{\mu}-1\|<1-{\frac{\alpha}{p}};\;(z{\in}{\mathbb{U}},\;0{\leq}{\alpha}<p)$$. In this paper several sufficient conditions for some classes of functions are investigated. The authors apply Jack's Lemma, to obtain this conditions. Furthermore, sufficient conditions for strongly starlike and convex p-valent functions of order ${\gamma}$ and type ${\beta}$, are also considered.

Extreme spirallike products

  • Lee, Suk-Young;David Oates
    • Communications of the Korean Mathematical Society
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    • v.10 no.4
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    • pp.875-880
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    • 1995
  • Let $S_p(\alpha)$ denote the class of the Spirallike functions of order $\alpha, 0 < $\mid$\alpha$\mid$ < \frac{\pi}{2}$ Let $\Pi_N$ denote the subset of $S_p(\alpha)$ consisting of all products $z\Pi^N_{j=1}(1-u_j z)^{-mt_j}$ where $m = 1 + e^{-2i\alpha},$\mid$u_j$\mid$ = 1, t_j > 0$ for $j = 1, \cdots, N$ and $\sum^{N}_{j=1}{t_j = 1}$. In this paper we prove that extreme points of $S_p(\alpha)$ may be found which lie in $\Pi_N$ for some $N \geq 2$. We are let to conjecture that all exreme points of $S_p(\alpha)$ lie in $\Pi_N$ for somer $N \geq 1$ and that every such function is an extreme point.

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Studies on the synthesis of N,N'-disubstituted thiourea derivatives and their antibacterial, antitubercular and antitumor activities (N,N'-diusbstituted thiourea derivatives의 합성과 항균성, 항인결핵성및 항종양 시험에 관한 연구)

  • 조윤성;이명걸
    • YAKHAK HOEJI
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    • v.14 no.1_2
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    • pp.1-14
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    • 1970
  • Seventeen N,N/sup I/-disubstituted thiourea derivatives were synthesized by the Hugershof reaction and reported. Antitumor activities of the synthesized compounds against ascitic Ehrlich Carcinoma and ascitic sarcoma 180 were reported. It was found that 1,1/sup I/-(p-Phenylene)-3,3/sup I/-bis (2-carboxyphenyl)-2,2/sup I/-dithiourea was considerably active against ascitic Ehrlich Carcinoma and Sarcoma 180 respectively. 1-(2-Carboxyphenyl)-3-(p-ethoxyphenyl)-2 thiourea was active against ascitic Sarcoma 180. 1-Salicyloyl-3-(p-ethoxyphenyl)-2-thiourea and 1,1/sup I/-(p-Phenylene)-3,3/sup I/-bis(2-hydroxyethyl)-2,2/sup I/-dithiourea were active against ascitic Ehrlich Carcinoma. Antitubercular activities of the synthesized compounds against Mycobacterium tuberculosis H/sub 37/ R/sub v/ were also reported. It was found that 1-Isonicotinyl-4-cyclohexyl-3-thiosemicarbazide was considerably active at 100 .mu.g/ml. 1,1/sup I/-(p-Phenylene)-3,3/sup I/-bis(2-hydroxyethyl)-2,2/sup I/-dithiourea and 1-Salicyloyl-3-(p-ethoxyphenyl)-2-thiourea were active at 1000 .mu.g/ml respectively. Antibacterial activities of nine compounds of the synthesized compounds against S. aureus and E. Coli were reported. It was found that 1,1-(p-Phenylene)-4,4/sup I/-bis(isonicotinyl)-2,2/sup I/-dithiosemicarbazide and 1-Isonicotinyl-4-cyclohexyl-3-thiosemicarbazide were considerably active against S. aureus and E. Coli respectively. 1-(6-Methyl-2-benzothiazolyl)-3-(1-naphthyl)-2-thiourea was active against S. aureus. 1,1/sup I/-(p-Phenylene)-3,3/sup I/-bis (2-hydroxyethyl)-2,2/sup I/-dithiourea was active against E. Coli.

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Categorical Research On the Past Chiefs of Presidential Security Service (역대 대통령경호실장 유형분석)

  • Cho, Kwang-Rae
    • Korean Security Journal
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    • no.33
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    • pp.229-260
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    • 2012
  • The purpose of this study is to categorize the past Chiefs of Presidenteal Security Service so far based on their level of expertise and authority so that we can identify some specific reasons as to why some of them are recognized as successful while others are not, and that the categorization will be a guideline to future successful administration. In order to do so, a quantitative research has been implemented through meetings of a group security science expert who has been in security business for substantial amount of time. The result is as following: Authoritative/professional: 2nd Chief of P.S.S. Park, Jong-Gyu, 5th Chief of P.S.S. Jang, Se-Dong, 7th Chief of P.S.S. Lee, Hyeon-Wu, 8th Chief of P.S.S. Choi, Seok-Rip. Authoritative/Non-professional: 1st Chief of P.S.S. Hong, Jong-cheol, 3rd Chief of P.S.S. Cha, Ji-cheol, 6th Chief of P.S.S. Ahn, Hyeon-Tae, 14th Chief of P.S.S. Kim, In-Jong. Non-authoritative/professional: 4th Chief of P.S.S. Jeong, Dong-Ho, 9th Chief of P.S.S. Park, Sang-Beom, 13th Chief of P.S.S. Yom. Sang-Guk. Non-authoritative/Non-professional: 10th Chief of P.S.S. Kim, Gwang-Seok, 11th Chief of P.S.S. Ahn, Ju-Seop, 12th Chief of P.S.S. Kim, Se-Ok. This categorization research on the Chief of P.S.S. suggests that any president, to be a successful one, must choose the Chief of P.S.S. based on his/her expertise in order to secure national security.

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On the harris ergodicity of a class of markov processes

  • Lee, Chan-Ho
    • Journal of the Korean Mathematical Society
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    • v.32 no.1
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    • pp.85-92
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    • 1995
  • Supppose ${X_n}$ is a Markov process taking values in some arbitrary state space $(S, F)$ with temporarily homogeneous transition probabilities $p^n(x, A) = P(X_n \in $A\mid$X_0 = x), x \in S, A \in F$. Write $p(x, A) for p^1(x, A)$.

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Effect of Mixture Ratio of Biochar and Peatmoss on the Growth of Aster spathulifolius (바이오차와 피트모스의 혼합비율이 해국 묘 생육에 미치는 영향)

  • Kim, S.J.;Kim, S.J.;Han, S.K.;Kwon, Y.K.;Kwon, Y.H.
    • Journal of Practical Agriculture & Fisheries Research
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    • v.20 no.2
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    • pp.31-38
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    • 2018
  • This study was conducted to investigate the possibility of biochar as an alternative medium to peatmoss using for Aster spathulifolius. We cultivated A. spathulifolius in four potting media with different mixing rates (v/v) of peatmoss (P) and biochar (B) as follows: B0+P3, B1+P2, B2+P1, and B3+P0 with vermiculite 3 + perlite 3. Also, we analyzed the chemical properties of media and the plant growth characteristics. The results were as follows: In case of media's chemical condition, B0+P3 and B1+P2 treatments showed higher tendency (p < 0.05). Plant height on B0+P3 and B1+P2 treatments was much higher than that on other treatments (p < 0.05). Root length on B1+P2 treatment was higher than on B0+P3 treatment (p < 0.05). B0+P3 and B1+P2 treatments showed higher number of leaves and dry biomass than other treatments. Therefore, our results support that Biochar : Peatmoss : Vermiculite : Perlite (1/3 : 2/3 : 1 : 1, v/v) could be a more economical potting medium for A. spathulifolius than peatmoss : vermiculite : perlite (1 : 1 : 1, v/v).

Rice variety IPB3S and IPB prima production technology to support food self-sufficiency in Indonesia

  • Aswidinnoor, Hajrial;Guntoro, Dwi;Sugiyanta, Sugiyanta;Wiyono, Suryo;Widodo, Widodo;Wijaya, Hermanu;Nindita, Anggi;Furqoni, Hafith
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.362-362
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    • 2017
  • Dissemination of IPB3S rice variety combined with cultivation technology named IPB Prima was aimed to introduce IPB research product particularly for IPB rice variety with high-yield character that is IPB3S. The rice variety IPB3S and IPB Prima cultivation technology was expected to be one of solution to improve rice productivity and accelerate to food self-sufficiency in Indonesia. Research sctivity was consist of three main research unit i.e. (1) Dissemination of IPB3S rice variety and IPB Prima production technology; (2) The development of Information and management web-based system (IMS) for planning and monitoring IPB3S and IPB Prima application distribution; and (3) The development of High-capacity grain drying system in Fluidized-bed drying ang in-store drying system. The objective of main research i.e. to introduce IPB high-yield rice variety, to accelerate rice productivity to support self-sufficiency, to develop integrated system model through fluidized and in-store drying, and to develop web-based management-information system in result analyzing IPB3S and IPB Prima distribution and technology application. The dissemination activities was arranged in two location. The first location was in Banyuwangi, East Java with total area 10.87 ha, consist of 8.91 ha planting area for IPB3S and 1.96 ha planting area for Ciherang. The second location is in Tegal, Middle Java with total planting area in 5 ha. The experiment was arranged in different treatment of varieties and cultivation method. The experiment consist of (1) rice variety Ciherang with conventional cultivation technology (P0); (2) rice variety Ciherang with IPB Prima cultivation technology (P1); (3) rice variety IPB3S with conventional cultivation technology (P2); (4) rice variety IPB3S with IPB Prima cultivation technology (P3). Planting distance for twin rows system is $50cm{\times}25cm{\times}12.5cm$. Planting distance for single row system is $25cm{\times}25cm$. The research result elucidated that productivity result in two location has different grades in similar trend. Experiment in Tegal resulted P0 result is $6.18ton\;ha^{-1}$, P1 result is $6.30ton\;ha^{-1}$, P2 result is $6.82ton\;ha^{-1}$, P3 result is $7.31ton\;ha^{-1}$. Experiment in Banyuwangi resulted optimum production of IPB3S variety productivity number are $7.29ton\;ha^{-1}$, while Ciherang are $6.73ton\;ha^{-1}$.

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Rice variety IPB3S and IPB prima production technology to support food self-sufficiency in Indonesia

  • Aswidinnoor, Hajrial;Guntoro, Dwi;Sugiyanta, Sugiyanta;Wiyono, Suryo;Widodo, Suryo;Wijaya, Hermanu;Nindita, Anggi;Furqoni, Hafith
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.61-61
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    • 2017
  • Dissemination of IPB3S rice variety combined with cultivation technology named IPB Prima was aimed to introduce IPB research product particularly for IPB rice variety with high-yield character that is IPB3S. The rice variety IPB3S and IPB Prima cultivation technology was expected to be one of solution to improve rice productivity and accelerate to food self-sufficiency in Indonesia. Research sctivity was consist of three main research unit i.e. (1) Dissemination of IPB3S rice variety and IPB Prima production technology; (2) The development of Information and management web-based system (IMS) for planning and monitoring IPB3S and IPB Prima application distribution; and (3) The development of High-capacity grain drying system in Fluidized-bed drying ang in-store drying system. The objective of main research i.e. to introduce IPB high-yield rice variety, to accelerate rice productivity to support self-sufficiency, to develop integrated system model through fluidized and in-store drying, and to develop web-based management-information system in result analyzing IPB3S and IPB Prima distribution and technology application. The dissemination activities was arranged in two location. The first location was in Banyuwangi, East Java with total area 10.87 ha, consist of 8.91 ha planting area for IPB3S and 1.96 ha planting area for Ciherang. The second location is in Tegal, Middle Java with total planting area in 5 ha. The experiment was arranged in different treatment of varieties and cultivation method. The experiment consist of (1) rice variety Ciherang with conventional cultivation technology (P0); (2) rice variety Ciherang with IPB Prima cultivation technology (P1); (3) rice variety IPB3S with conventional cultivation technology (P2); (4) rice variety IPB3S with IPB Prima cultivation technology (P3). Planting distance for twin rows system is $50cm{\times}25cm{\times}12.5cm$. Planting distance for single row system is $25cm{\times}25{\times}cm$. The research result elucidated that productivity result in two location has different grades in similar trend. Experiment in Tegal resulted P0 result is $6.18ton\;ha^{-1}$, P1 result is $630ton\;ha^{-1}$, P2 result is $6.82ton\;ha^{-1}$, P3 result is $7.31ton\;ha^{-1}$. Experiment in Banyuwangi resulted optimum production of IPB3S variety productivity number are 7.29 ton ha-1, while Ciherang are $6.73ton\;ha^{-1}$.

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