• Title/Summary/Keyword: S1P

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A Study of the Expansion of E.R.P.S. Adoption (E.R.P 도입의 확대 방안)

  • Park, Lee-Bong
    • Management & Information Systems Review
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    • v.19
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    • pp.199-221
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    • 2006
  • The purpose of this study is to expand businesses' adoption of the Enterprise Resource Planning System (E.R.P.S.). In order to accomplish the objective, the following conditions need to be fulfilled. 1) Clearness of the goal and expected effect of E.R.P.S. adoption 2) Definiteness of the extent of E.R.P.S. construction 3) The management's will to E.R.P.S. adoption If the E.R.P.S is adopted, the following effects are expected. 1) Speedy quality decision-making is possible. 2) Time taken from the order of the product to its release can be curtailed (from 40days to 10days). 3) Time taken for the development of the product can be shortened (from 24 months to 10 months). 4) Cost reduction is possible by using necessary information in real time.

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Synthesis and Antimicrobial Screening of Some Fluorinated Azoles Containing (2-(6-Methyl-2-P-tolyl-lH-imidazo[1,2-a]pyridin-3-yl) Nucleus ((2-(6-Methyl-2-P-tolyl-lH-imidazo[1,2-a]pyridin-3-yl)핵종을 가지고 있는 불소화된 아조화합물의 합성과 항균활성의 스크리닝)

  • Shelke, Sharad;Salunkhe, Nilesh;Sangale, Sandeep;Bhalerao, Swapnil;Naik, Nilesh;Mhaske, Ganesh;Jadhav, Ranjana;Karale, Bhausaheb
    • Journal of the Korean Chemical Society
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    • v.54 no.1
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    • pp.59-64
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    • 2010
  • The synthesis of a series of fluorinated thiadiazoles 3, triazoles 4 and oxadiazoles 5 are synthesized from thiosemicarbazides 2 containing (2-(6-methyl-2-p-tolyl-lH-imidazo[1,2-a]pyridin-3-yl nucleus. These reactions were carried out by conventional method as well as ultra sound irradiation method. All products have been characterized by IR, 1H NMR, MS study and screened for their antimicrobial activity.

Hyperspaces and the S-equivariant Complete Invariance Property

  • Maury, Saurabh Chandra
    • Kyungpook Mathematical Journal
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    • v.55 no.1
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    • pp.219-224
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    • 2015
  • In this paper it is investigated as to when a nonempty invariant closed subset A of a $S^1$-space X containing the set of stationary points (S) can be the fixed point set of an equivariant continuous selfmap on X and such space X is said to possess the S-equivariant complete invariance property (S-ECIP). It is also shown that if X is a metric space and $S^1$ acts on $X{\times}S^1$ by the action $(x,p){\cdot}q=(x,p{\cdot}q)$, where p, $q{\in}S^1$ and $x{\in}X$, then the hyperspace $2^{X{\times}S^1}$ of all nonempty compact subsets of $X{\times}S^1$ has the S-ECIP.

Partial Purification of Factors for Differential Transcription of the rrnD Promoters for Ribosomal RNA Synthesis in Streptomyces coelicolor

  • Hahn, Mi-Young;Roe, Jung-Hye
    • Journal of Microbiology
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    • v.45 no.6
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    • pp.534-540
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    • 2007
  • The Streptomyces coelicolor A3(2) genome contains six operons (rrnA to F) for ribosomal RNA synthesis. Transcription from rrnD occurs from four promoters (p1 to p4). We found that transcripts from the p1 and p3 promoters were most abundant in vivo in the early exponential phase. However, at later phases of exponential and stationary growth, transcripts from the p1 promoter decreased drastically, with the p3 and p4 transcripts constituting the major forms. Partially purified RNA polymerase supported transcription from the p3 and p4 promoters, whereas pure reconstituted RNA polymerase with core enzyme (E) and the major vegetative sigma factor ${\sigma}^{HrdB}$ ($E{\cdot}{\sigma}^{HrdB}$) did not. In order to assess any potential requirement for additional factor(s) that allow transcription from the p3 and p4 promoters, we fractionated a partially purified RNA polymerase preparation by denaturing gel filtration chromatography. We found that transcription from the p3 and p4 promoters required factor(s) of about 30-35 kDa in addition to RNAP holoenzyme ($E{\cdot}{\sigma}^{HrdB}$). Therefore, transcription from the p3 and p4 promoters, which contain a consensus -10 region but no -35 for ${\sigma}^{HrdB}$ recognition, are likely to be regulated by transcription factor(s) that modulate RNA polymerase holoenzyme activity in S. coelicolor.

Fabrication and Characterization of InP JFET's for OEIC's (광전자집적회로를 위한 InP JFET의 제작 및 특성 분석)

  • 박철우;정창오;김성준
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.29A no.10
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    • pp.29-34
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    • 1992
  • JFET's with gate lengths ranging from 1$\mu$m to 8.3$\mu$m are successfully fabricated on InP substrate where the long haul (1.3$\mu$m~8.3$\mu$m) OEIC's(OptoElectronic Integrated Circuits) have been made. The pn junction of InP JFET's is made by co-implantation and RTA process. JFET's have etched-mesa-gate structure and the maximum gm larger than 90mS/mm was measured and this is the highest record in JFET's of such structure without S/D n$^{+}$ ion implantation. To maintain maximum g$_m$ should be well controlled the overetch of n-layer which inevitably occurs during etching off the unused p-layer. The I-V characteristic is checked during p-layer etch, for this purpose. A dc voltage gain of 11 is obtained from a preamplifier circuit thus fabricated.

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A Study on Successful Community of Practice Strategy and Implementation : Case Study of 'S' Corporation's Knowledge Management (성공적 지식경영을 위한 CoP 운영전략 : S사의 지식경영구축 사례를 중심으로)

  • Bang, Yoo-Sung;Lee, Myung-Sung
    • Knowledge Management Research
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    • v.1 no.1
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    • pp.127-137
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    • 2000
  • Effective knowledge sharing and creating requires human networking as well as system. Corporation 'S' organized 'community of practice(CoP),' which is a virtual group based on work process, skill, and interest. The purpose of this study is to suggest effective CoP establishment and implementation methods, based upon 'S' experience. The effective methods this study suggests are : setting up clear CoP objectives by each CoP; dual CoP system with career centered and subject centered; alignment with business strategy; guide by knowledge integrator, and professional competence development as CoP purpose. Key success factors to CoP activities also include effective communication, facilitators' competency, and managers' support.

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Pathological Changes in Rats Fed petasites japonicus Maxim II. Immunohistochemical Localization of Cytochrome P4502E1 and GST-P in Liver

  • Jee, Young-Heun;Lee, Cha-Soo;Jeong, Kyu-Shik
    • Korean Journal of Veterinary Pathology
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    • v.1 no.1
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    • pp.33-39
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    • 1997
  • We investigated metabolism and carcinogenesis in livers of Sprague-Dawley rats fed juices and pelleted diets containing Korean native plants petasites japonicus Maxim by evaluating cell localization and expression of cytochrome P450s and GST-P. Anti-cytochrome P450s application in liver sections revealed three to four times increased expression of cytochrome P450E1 immunoreactivity in degenerative hepatocytes when compared to histologically normal hepatocytes. Anti-GST-P in showed positive pren plastic foci as well as in individual hepatocytes randomly scattered throughout all liver sections examined. Additionally GST-P was evident in proliferative endothelial cells and biliary epithelial cells in exposed rat livers. These results suggested that the increased level of cytochrome P4502E1 in affected hepatocytes was a direct consequence of Petasites japonicus toxicity. Further immunoreactivity to anti-GST-P in hepatocytes endothelial cells and biliary epithelial cells indicated a possible preneoplastic effects of Petasites japonicus in Sprague-Dawley rat.

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Antimutagenic and Antibacterial Activities of Korean and American Propolis (한국산과 미국산 프로폴리스의 항돌연변이 및 항균효과)

  • Jang, Il-Woong;Park, Jeong-Seob;Kwon, Hyoung-Cheol;Jung, Mun-Yhung;Choi, Dong-Seong
    • Korean Journal of Food Science and Technology
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    • v.41 no.6
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    • pp.694-699
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    • 2009
  • The antimutagenic activities of ethanol extracts of Korean and American propolis were tested using Salmonella Typhimurium TA98 with two indirect mutagens of 3-amino-1,4-dimethyl-5H-pyrido [4,3-b]indole (Trp-P-1) and 2-aminoanthracene (2-AA) with S9 mix. Additionally, their antimicrobial activities against acne-related pathogenic strains of Propionibacterium acnes, Staphylococcus Epidermidis, Staphylococcus aureus and Pseudomonas aeruginosa were evaluated using both paper disk method and agar dilution method. Ethanol extracts of Korean and American propolis showed strong inhibitory effects, in a dose dependant manner, against the mutagenicities induced by Trp-P-1 and 2-AA. The antimutagenic effect of ethanol extracts of Korean propolis showed significantly higher protective activity than that of American propolis against the Trp-P-1 induced mutagenicity of S. Typhimurium TA98 at the lower concentration ($1-10\;{\mu}g$), but significantly lower protective activity at the higher concentration ($50-200\;{\mu}g$). The antimutagenic effect of ethanol extract of Korean propolis showed significantly higher protective activity than that of American propolis against the 2-AA induced mutagenicity at the concentration of $1\;{\mu}g$, but significantly lower protective activity than that of the American at the higher concentration ($50-200\;{\mu}g$). Both extracts showed strong antimicrobial activities against all the acne-related pathogens tested, with minimal inhibitory concentration (MIC) values in the range $1,500-5,000\;{\mu}g/mL$.

Relationship between Public Health Nurse's Decentralization, Participation of Decision-making and Organizational Commitment (보건소 간호사의 분권화, 의사결정 참여 및 조직몰입의 관계)

  • Cho, Mee-Kyung;Jeong, Hyun-Sook;Kim, Tae-Sook
    • Journal of Korean Academy of Nursing Administration
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    • v.5 no.1
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    • pp.99-111
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    • 1999
  • The purpose of this study was to investigate the relationship between public health nurse's decentralization, participation of decision-making and organizational commitment and to provide basic data for the improvement of public health nurse's organizational effectiveness. Data were collected from Aug. 1 to Aug. 30, 1998 (collection rate-96%) through questionnaires by 163 public health nurses working in Taejon and Chungnam. The instruments were used Van de Ven and Ferry's Job Authority scale, Hage and Aiken's Hierarchy of Authority scale. Participation of Decision-making scale. and Mowday's Organizational Commitment Questionnaires. Collected data were analyzed by SPSS PC+. The results were as follows 1. There were significant differences of age(P<.05), career, spending time for major study, and experience who called expert(P<.01) to decentralization. 2. There were significant differences of career (P<.05), educational level, and spending time for major study(P<'OOl) to participation of decision-making. 3. There were significant differences of career. spending time for D1ajor study, self-evaluation to specialty(P<.01) and experience who called expert (P<.001) to organizational commitment. 4. 1) A significant correlation was found between decentralization and self-evaluation to specialty (P<.05), age, career, spending time for major study, and experience who called expert (P<.01.). 2) A significant correlation was found between participation of decision-making and self-eval-uation to specialty(P<.05), age, career, spending time for major study, experience to call expert, and decentralization (P<.01). 3) A significant correlation was found between organizational commitment and age(P<.05). career. spending time for major study, self-eval-uation to specialty, experience who called expert. decentralization, and participation of decision-making (P<.01). 5. Decentralization w·as the best predictor of or ganizational commitment(17%), also experience who called expert, self-evaluation to specialty explained the organizational commitment.

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