• Title/Summary/Keyword: S1P

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Clinical Analysis Of Ventricular Septal Defect (심실중격결손증의 외과적 고찰)

  • Seong, Suk-Hwan;Suh, Kyung-Pill
    • Journal of Chest Surgery
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    • v.15 no.1
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    • pp.90-97
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    • 1982
  • Two hundred one patients of ventricular septal defect, which were operated at Seoul National University Hospital, were analysed on clinical background during the period from January, 1975 to December, 1980. The results were as follows: 1. Of the 201 patients, 118 patients were male [58.7%] and 83 patients were female [41.3%]. Their age ranged from 15 months to 40 years, and the mean age was 8.7 years. 40% of the patients were between 4 and 8 years. 2. The most common symptoms showed frequent U RI and exertional dyspnea. 3. On Kirklin`s anatomical classification, type I constituted 26.9%, type II 58.2%, type III 12.4%, and type IV 1.0%. We showed marked increased incidence of type I VSD as compared to Caucasians* 4. 46 cases were associated with other congenital cardiac diseases. They were PDA [13 cases], AI[11 ], ASD[6], PS[10], MI[4], and Double aortic arch [1]. 5. In 128 patients, who had complete hemodynamic data and were not associated with other congenital cardiac diseases, an attempt was made to correlate the EKG findings with the hemodynamic data, and defect size with the hemodynamic data. The children had variable distribution of PA syst. pr. and Rp/Rs. But most of adults had $R_P$/$R_S$of 0.15 or less. As $P_P$/$P_S$increased, the rate of operative complication increased also. 6. When a normal EKG pattern was present, $Q_P$/$Q_S$and $R_P$/$R_S$and $P_P$/$P_S$were relatively low. When EKG findings were LVH pattern, there was diastolic volume overload to left ventricle. As RVH, there was systolic pressure overload to right ventricle. And as BVH, there was mixed pattern of diastolic volume overload to left ventricle and systolic pressure overload to right ventricle. 7. Among patients in defect was less than 1 $cm^2$ per $M^2$ of BSA, $Q_P$/$Q_S$was less than 2:1, and $R_P$/$R_S$less than 0.25, and PAsyst. pr. less than 50 mmHg, and $P_P$/$P_S$was less than 0.5. But patients with the defect greater than 1 $cm^2$ per $M^2$ of BSA had no correlationship between $Q_P$/$Q_S$, $R_P$/$R_S$, PAsyst. pr. and defect size in each other. Most of patients with the defect greater than 2 $cm^2$/$M^2$ BSA, $R_P$/$R_S$was greater than 0.5. 8. Operative mortality rate was 9.5% [19 cases] among 201 patients. And complication rate including mortality rate was 22.9% [46 cases].

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REPEATED-ROOT CONSTACYCLIC CODES OF LENGTH 2ps OVER GALOIS RINGS

  • Klin-eam, Chakkrid;Sriwirach, Wateekorn
    • Bulletin of the Korean Mathematical Society
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    • v.56 no.1
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    • pp.131-150
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    • 2019
  • In this paper, we consider the structure of ${\gamma}$-constacyclic codes of length $2p^s$ over the Galois ring $GR(p^a,m)$ for any unit ${\gamma}$ of the form ${\xi}_0+p{\xi}_1+p^2z$, where $z{\in}GR(p^a,m)$ and ${\xi}_0$, ${\xi}_1$ are nonzero elements of the set ${\mathcal{T}}(p,m)$. Here ${\mathcal{T}}(p,m)$ denotes a complete set of representatives of the cosets ${\frac{GR(p^a,m)}{pGR(p^a,m)}}={\mathbb{F}}p^m$ in $GR(p^a,m)$. When ${\gamma}$ is not a square, the rings ${\mathcal{R}}_p(a,m,{\gamma})=\frac{GR(p^a,m)[x]}{{\langle}x^2p^s-{\gamma}{\rangle}}$ is a chain ring with maximal ideal ${\langle}x^2-{\delta}{\rangle}$, where ${\delta}p^s={\xi}_0$, and the number of codewords of ${\gamma}$-constacyclic code are provided. Furthermore, the self-orthogonal and self-dual ${\gamma}$-constacyclic codes of length $2p^s$ over $GR(p^a,m)$ are also established. Finally, we determine the Rosenbloom-Tsfasman (RT) distances and weight distributions of all such codes.

Anilinolysis of Diphenyl Thiophosphinic Chloride and Theoretical Studies on Various R1R2P(O or S)Cl

  • Dey, Nilay Kumar;Han, In-Suk;Lee, Hai-Whang
    • Bulletin of the Korean Chemical Society
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    • v.28 no.11
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    • pp.2003-2008
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    • 2007
  • The aminolysis of diphenyl thiophosphinic chloride (2) with substituted anilines in acetonitrile at 55.0 oC is investigated kinetically. Kinetic results yield large Hammett ρX (ρnuc = ?3.97) and Bronsted βX (βnuc = 1.40) values. A concerted mechanism involving a partial frontside nucleophilic attack through a hydrogen-bonded, four-center type transition state is proposed on the basis of the primary normal kinetic isotope effects (kH/kD = 1.0-1.1) with deuterated aniline (XC6H4ND2) nucleophiles. The natural bond order charges on P and the degrees of distortion of 42 compounds: chlorophosphates [(R1O)(R2O)P(=O)Cl], chlorothiophosphates [(R1O)(R2O)P(=S)Cl], phosphonochloridates [(R1O)R2P(=O)Cl], phosphonochlorothioates [(R1O)R2P(=S)Cl], chlorophosphinates [R1R2P(=O)Cl], and chlorothiophosphinates [R1R2P(=S)Cl] are calculated at the B3LYP/ 6-311+G(d,p) level in the gas phase.

Performance of Crossbred Sahiwal Cattle at the Pabna Milkshed Area in Bangladesh

  • Islam, S.S.;Bhuiyan, A.K.F.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.10 no.6
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    • pp.581-586
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    • 1997
  • The present study analysed the various productive and reproductive characteristics of 1/2 Pabna Milking Cows (PMC)-1/2 Sahiwal (S) and 1/4 PMC-3/4 S collected from the Pabna milkshed area at Baghabarighat, Sirajgonj, Bangladesh. The studied traits were birth weight (BWT), age at puberty (AP), number of services per conception (NSC), post partum heat period (PPHP), gestation period (GP), daily milk yield (DMY), lactational production (LP), lactation length (LL), fat percentage and solids-not-fat percentage (SNFP). Five individual Sahiwal sires were used for the upgrading of Pabna Milking Cows. The used data covered from 1987 to 1994. Least-squares analysis of variance showed that genetic group had a significant effect on BWT (P < 0.05), AP (p < 0.01), DMY (p < 0.01), LP (p < 0.001), LL (p < 0.05), FP (p < 0.05) and SNFP (p < 0.01). Genetic group had non-significant effect on NSC, GP and PPHP. The effect of sire was significant on BWT (p < 0.01), NSC (p < 0.01), LP (p < 0.05) and LL (p < 0.05). The AP, NSC, DMY, LP, LL and SNFP were higher in 1/2 PMC-1/2S cows; BWT and PPHP were higher in 1/4 PMC-3/4S but GP and FP were almost same in both genetic groups. From this study it may be concluded that production and use of 1/2 PMC-1/2S would seem more profitable for commercial milk production in the Bangladesh Milk Producers' Cooperative Union Limited (BMPCUL) area and at the same time emphasis should be given on rigorous sire selection.

Diagnostic Utility of Pleural Fluid Soluble Triggering Receptor Expressed on Myeloid Cells 1 Protein in Patients with Exudative Pleural Effusion (삼출성흉수에서 Soluble Triggering Receptor Expressed on Myeloid Cells 1 Proteion의 진단적 유용성)

  • Sim, Yun Su;Lee, Jin Hwa;Cheun, En Mi;Chang, Jung Hyun
    • Tuberculosis and Respiratory Diseases
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    • v.62 no.6
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    • pp.499-505
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    • 2007
  • Background: Triggering receptor expressed on myeloid cells 1 protein (TREM-1) is a cell surface molecule expressed on neutrophils and monocytes, and it plays an important role in myeloid cell-activated inflammatory response. The aim of this study was to investigate the diagnostic efficiency of soluble (s) TREM-1 in the patients who had pleural effusion from various causes. Methods: Forty-five patients with exudative pleural effusion were included in this study. The level of sTREM-1 was measured in both the serum and pleural fluids by immunoblot assay with using human-sTREM-1 antibody. Results: The pleural fluid sTREM-1 was significantly different in the three groups of exudative pleural effusion (p=0.011). Particularly, the patients with parapneumonic effusion were found to have significantly higher pleural fluid levels of sTREM-1 than patients with tuberculous (p<0.05) and malignant effusion, respectively (p<0.05). However, the serum sTREM-1 did not show a significant difference in the three groups. In order to evaluate the diagnostic utility of pleural fluid sTREM-1, the receiver operating characteristic (ROC) curve was constructed and the area under the curve (AUC) was 0.818 (p=0.001). Using a cutoff value of 103.5 pg/mL for the pleural fluid sTREM-1, the sensitivity and specificity were 73% and 81%, respectively, for differentiating parapneumonic effusion from tuberculous or malignant effusions. Conclusion: Pleural fluid sTREM-1 can be an additional marker for making the differential diagnosis of pleural effusion.

Invariant Trace Fields of Chain Links

  • Ryou, Kazuhiro
    • Kyungpook Mathematical Journal
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    • v.56 no.1
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    • pp.257-271
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    • 2016
  • In this paper, we compute the trace field of C(2, s), the complement of two component chain link with s left half twists in ${\mathbb{S}}^3$, for every s. As a result, for every $n{\in}{\mathbb{N}}{\backslash}\{1\}$, we can find $s{\in}{\mathbb{Z}}$ such that the degree of the trace field of C(2, s) is n. We also prove that if for fixed p, the degree of the trace field of C(p, s) runs over ${\mathbb{N}}{\backslash}\{1\}$, then p is contained in {1, 2, 4, 8}.

The Changes of Chlorophylls in Blanched and Fermented Chinese Cabbage (배추의 가열과 산 발효에 따른 Chlorophylls의 변화)

  • 김예숙;이혜수
    • Korean journal of food and cookery science
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    • v.1 no.1
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    • pp.27-32
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    • 1985
  • The changes of chlorophylls and pH of cooked water were investigated in blanched and fermented cabbage. In blanched cabbage, pheophytins were increased markedly with heating time. This was related to the changes of pH and the effects of heat. One minute blanching accelerated the formation of chlorophyllides by the activation of chlorophyllase. In fermented cabbage, pH and chlorophylls were decreased rapidly at the beginning of fermentation. At the final of fermentation, all chlorophylls and chlorophyllides were converted to pheophytins ana pheophorbides, and the content of pheophytins was higher than the content of pheophorbides. The content of pheophorbides in fermented cabbage was higher than that in blanched cabbage.

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Effect of Sphingosine-1-Phosphate on Intracellular Free Ca2+ in Cat Esophageal Smooth Muscle Cells

  • Lee, Dong Kyu;Min, Young Sil;Yoo, Seong Su;Shim, Hyun Sub;Park, Sun Young;Sohn, Uy Dong
    • Biomolecules & Therapeutics
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    • v.26 no.6
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    • pp.546-552
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    • 2018
  • A comprehensive collection of proteins senses local changes in intracellular $Ca^{2+}$ concentrations ($[Ca^{2+}]_i$) and transduces these signals into responses to agonists. In the present study, we examined the effect of sphingosine-1-phosphate (S1P) on modulation of intracellular $Ca^{2+}$ concentrations in cat esophageal smooth muscle cells. To measure $[Ca^{2+}]_i$ levels in cat esophageal smooth muscle cells, we used a fluorescence microscopy with the Fura-2 loading method. S1P produced a concentration-dependent increase in $[Ca^{2+}]_i$ in the cells. Pretreatment with EGTA, an extracellular $Ca^{2+}$ chelator, decreased the S1P-induced increase in $[Ca^{2+}]_i$, and an L-type $Ca^{2+}$-channel blocker, nimodipine, decreased the effect of S1P. This indicates that $Ca^{2+}$ influx may be required for muscle contraction by S1P. When stimulated with thapsigargin, an intracellular calcium chelator, or 2-Aminoethoxydiphenyl borate (2-APB), an $InsP_3$ receptor blocker, the S1P-evoked increase in $[Ca^{2+}]_i$ was significantly decreased. Treatment with pertussis toxin (PTX), an inhibitor of $G_i$-protein, suppressed the increase in $[Ca^{2+}]_i$ evoked by S1P. These results suggest that the S1P-induced increase in $[Ca^{2+}]_i$ in cat esophageal smooth muscle cells occurs upon the activation of phospholipase C and subsequent release of $Ca^{2+}$ from the $InsP_3$-sensitive $Ca^{2+}$ pool in the sarcoplasmic reticulum. These results suggest that S1P utilized extracellular $Ca^{2+}$ via the L type $Ca^{2+}$ channel, which was dependent on activation of the $S1P_4$ receptor coupled to PTX-sensitive $G_i$ protein, via phospholipase C-mediated $Ca^{2+}$ release from the $InsP_3$-sensitive $Ca^{2+}$ pool in cat esophageal smooth muscle cells.

Characteristics of Phosphorus Accumulation in Rotation System of Plastic Film House and Paddy Soils (시설재배지에서 윤답전환체계가 인산분포에 미치는 영향)

  • Lee, Yong-Bok;Lee, In-Bog;Hwang, Jun-Young;Lee, Kyung-Dong;Kim, Pil-Joo
    • Korean Journal of Soil Science and Fertilizer
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    • v.35 no.1
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    • pp.47-58
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    • 2002
  • Much of the plastic film house soils in the southern part of the Korean peninsula are managed using a upland-paddy rotation culture system (hereafter, RS) to prevent salt accumulation in soil. However, information on the effects of RS on soil properties and environmental conservation is limited. In order to determine the effects of RS on soil properties, 22 fields under RS and 20 fields under a non-rotation system (hereafter, NRS) in plastic film houses were selected in Chinju, in southern Korea, and the P distribution characteristics were investigated, including the chemical properties. The RS contributed to the removal of water-soluble salts in the surface layer and to the redistribution of organic matter evenly in the soil profile. In the AP horizon, available phosphorus levels were $1,611mg\;kg^{-1}$ in RS and $1,789mg\;kg^{-1}$ in NRS, which markedly exceeds the optimum range for plant cultivation. Total P was lower in RS (average $4,593mg\;kg^{-1}$) than in NRS (average $5,440mg\;kg^{-1}$) and this decrease was taken to be an effect of RS. Inorganic P was the predominant form of P in both systems, followed by organic P and residual P. A soil profile showed that total and inorganic P concentrations decreased with depth in both systems. However, organic P increased withdepth in RS, which was in contrast to that noted in NRS. The increase in organic P with depth in RS implied that organically rather than inorganically derived phosphate moved through the soil. The concentrations of water-soluble P, Ca-P and Al-P were higher in NRS than in RS soil profiles, but the Fe-P concentration was higher in RS than in NRS, which might be affected by the anaerobic conditions found in paddy soils. In both systems, the Al-P form of extractable P predominated in the surface layer, followed by Ca-P, Fe-P and water-soluble P. With increasing depth, the composition rate of Ca-P to extractable P decreased to less than 10% in the 60-70cm depth, as Fe-P dominated at this level. The content of water-soluble P, potentially the main source of eutrophication, was higher in NRS than in RS. These results indicated that the RS used in plastic film houses contributed to the removal of water-soluble salts but only slightly decreased the phosphate concentration.

COMPOSITION OPERATORS ON THE PRIVALOV SPACES OF THE UNIT BALL OF ℂn

  • UEKI SEI-ICHIRO
    • Journal of the Korean Mathematical Society
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    • v.42 no.1
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    • pp.111-127
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    • 2005
  • Let B and S be the unit ball and the unit sphere in $\mathbb{C}^n$, respectively. Let ${\sigma}$ be the normalized Lebesgue measure on S. Define the Privalov spaces $N^P(B)\;(1\;<\;p\;<\;{\infty})$ by $$N^P(B)\;=\;\{\;f\;{\in}\;H(B) : \sup_{0 where H(B) is the space of all holomorphic functions in B. Let ${\varphi}$ be a holomorphic self-map of B. Let ${\mu}$ denote the pull-back measure ${\sigma}o({\varphi}^{\ast})^{-1}$. In this paper, we prove that the composition operator $C_{\varphi}$ is metrically bounded on $N^P$(B) if and only if ${\mu}(S(\zeta,\delta)){\le}C{\delta}^n$ for some constant C and $C_{\varphi}$ is metrically compact on $N^P(B)$ if and only if ${\mu}(S(\zeta,\delta))=o({\delta}^n)$ as ${\delta}\;{\downarrow}\;0$ uniformly in ${\zeta}\;\in\;S. Our results are an analogous results for Mac Cluer's Carleson-measure criterion for the boundedness or compactness of $C_{\varphi}$ on the Hardy spaces $H^P(B)$.