• Title/Summary/Keyword: S.M.R

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New Transition Metal Mediated Alkylation Reaction of arachno-$S_{2}B_{7}H_{8}$, Insertion Reaction of arachno-$S_{2}B_{7}H_{8}^{-}$ with $(CO)_{5}M$ {${C(R_{1})(R_{2})}$} $(M=Cr,\;W;\;R_{1}=CH_{3},\;C_{6}H_{5};\;R_{2}=OCH_{3},\;SC_{6}H{5})$: Synthesis and Characterization of arachno-$4-RCH_{2}-6,8-S_{2}B_{7}H_{8}\;(R=CH_{3},\;IIa;\;C_{6}H_{5},\;IIb)$

  • Hee-Joo Jeon;Jae-Jung Ko;Kang-bong Lee;Sang Ook Kang
    • Bulletin of the Korean Chemical Society
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    • v.14 no.1
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    • pp.113-117
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    • 1993
  • Good yield synthetic routes for the production of new B-alkyl-dithiaborane clusters are reported. The syntheses of the B-alkyl-dithiaboranes are based on the use of Fischer-type carbene reagents to activate the B-H bonds of dithiaborane for alkyl-addition reactions and are the first examples of transition-mediated reactions of dithiaborane to be reported. Thus, reactions employing arachno-$S_2B_7H_8$- and $(CO)_5M{C(R_1)R_2}$ (M = Cr, W; $R_1 = CH_3,\;C_6H_5;\; R_2 = OCH_3,\;SC_6H_5)$ were found to yield the intermidiate anions I, $[(CO)_5M{C(R_1)R_2S_2B_7H_8}]^-$, which upon protonation gave the corresponding neutral, air-sensitive cluster arachno-4-$RCH_2-6,8-S_2B_7H_8(R=CH_3,\;IIa;\;C_6H_5,\;IIb)$ range from 30 to 35% yield. Complexes IIa and IIb are isoelectronic with arachno-6,8-$S_2B_7H_9$ and, on the basis of the spectroscopic data, are proposed to adopt a similar arachno cage geometry in which an $RCH_2$ units are substituted to 4 position boron atom of the arachno-6,8-$S_2B_7H_9$.

Phytosociological Studies on the Beech(Fagus multinervis Nakai) Forest and the Pine (Pinus parviflora S. et Z.) Forest of Ulreung Island, Korea (한국 울릉도의 너도밤나무(Fagus multinervis Nakai)림 및 섬잣나무(Pinus parviflora S. et Z.)림의 식물사회학적 연구)

  • 김성덕
    • Journal of Plant Biology
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    • v.29 no.1
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    • pp.53-65
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    • 1986
  • The montane forests of Ulreung Island, Korea, were investigated by the ZM school method. By comparing the montane forests of this island with those of Korean Peninsula and of Japan, a new order, F a g e t a l i a m u l t i n e r v i s, a new alliance, F a l g i o n m u l t i n e r v i s, a new association, H e p a t i c o-F a g e t u m m u l t i n e r v i s and Rhododendron brachycarpum-Pinus parviflora community were recognized. The H e p a t i c o - F a g e t u m m u l t i n e r v i s was further subdivided into four subassociations; Subass. of Sasa kurilensis, Subass. of Rumohra standishii, Subass. of Rhododendron brachycarpum and Subass. of typicum. Each community was described in terms of floristic, structural and environmental features.

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Cytotoxicity of Compound K (IH-901) and Ginsenoside Rh2, Main Biotransformants of Ginseng Saponins by Bifidobacteria, against Some Tumor Cells

  • Shin, Ji-Eun;Park, Eun-Kyung;Kim, Eun-Jin;Hong, Yoon-Hee;Lee, Kyung-Tae;Kim, Dong-Hyun
    • Journal of Ginseng Research
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    • v.27 no.3
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    • pp.129-134
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    • 2003
  • When ginsenoside $R_{*}$b1/ and $R_{b2}$ were anaerobically incubated with human fecal microflora, these ginsenosides were metabolized to compound K (IH-901). When ginsenoside $R_{g3}$ was anaerobically incubated with human fecal microflora, the ginsenoside $R_{g3}$ was metabolized it to ginsenoside $R_{h2}$. Among ginsenosides, IH-901 and 20(S)-ginsenoside $R_{h2}$ exhibited the most potent cyotoxicity against tumor cells: 50% cytotoxic concentrations of IH-901 in the media with and without fetal bovine serum (FBS) were 27.1-31.6 $\mu$M and 0.1-0.61 $\mu$M, and those of 20(S)-ginsenoside $R_{h2}$ were 37.5->50 and 0.7-7.1 $\mu$M, respectively. The cytotoxic potency of ginsenosides was IH-901>20(S)-ginsenoside R $h_{h2}$》20(S)-ginsenoside $R_{g3}$>ginsenoside $R_{b1}$(equation omitted) $R_{b2}$.EX>$R_{b2}$./.

Overexpression of afsR and Optimization of Metal Chloride to Improve Lomofungin Production in Streptomyces lomondensis S015

  • Wang, Wei;Wang, Huasheng;Hu, Hongbo;Peng, Huasong;Zhang, Xuehong
    • Journal of Microbiology and Biotechnology
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    • v.25 no.5
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    • pp.672-680
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    • 2015
  • As a global regulatory gene in Streptomyces, afsR can activate the biosynthesis of many secondary metabolites. The effect of afsR on the biosynthesis of a phenazine metabolite, lomofungin, was studied in Streptomyces lomondensis S015. There was a 2.5-fold increase of lomofungin production in the afsR-overexpressing strain of S. lomondensis S015 N1 compared with the wild-type strain. Meanwhile, the transcription levels of afsR and two important genes involved in the biosynthesis of lomofungin (i.e., phzC and phzE) were significantly upregulated in S. lomondensis S015 N1. The optimization of metal chlorides was investigated to further increase the production of lomofungin in the afsR-overexpressing strain. The addition of different metal chlorides to S. lomondensis S015 N1 cultivations showed that CaCl2, FeCl2, and MnCl2 led to an increase in lomofungin biosynthesis. The optimum concentrations of these metal chlorides were obtained using response surface methodology. CaCl2 (0.04 mM), FeCl2 (0.33 mM), and MnCl2 (0.38 mM) gave a maximum lomofungin production titer of 318.0 ± 10.7 mg/l, which was a 4.1-fold increase compared with that of S. lomondensis S015 N1 without the addition of a metal chloride. This work demonstrates that the biosynthesis of phenazine metabolites can be induced by afsR. The results also indicate that metal chlorides addition might be a simple and useful strategy for improving the production of other phenazine metabolites in Streptomyces.

ALMOST PRINCIPALLY SMALL INJECTIVE RINGS

  • Xiang, Yueming
    • Journal of the Korean Mathematical Society
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    • v.48 no.6
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    • pp.1189-1201
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    • 2011
  • Let R be a ring and M a right R-module, S = $End_R$(M). The module M is called almost principally small injective (or APS-injective for short) if, for any a ${\in}$ J(R), there exists an S-submodule $X_a$ of M such that $l_Mr_R$(a) = Ma $Ma{\bigoplus}X_a$ as left S-modules. If $R_R$ is a APS-injective module, then we call R a right APS-injective ring. We develop, in this paper, APS-injective rings as a generalization of PS-injective rings and AP-injective rings. Many examples of APS-injective rings are listed. We also extend some results on PS-injective rings and AP-injective rings to APS-injective rings.

Cytogenetic Study of Maackia amurensis Rupr. & Maxim. and M. fauriei (Levl.) Takeda Using Karyotyping Analysis and the FISH Technique (핵형분석과 FISH 기술을 이용한 솔비나무와 다릅나무의 세포유전학적 연구)

  • Kim, Soo-Young;Kim, Chan-Soo
    • Korean Journal of Plant Taxonomy
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    • v.39 no.3
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    • pp.193-198
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    • 2009
  • Chromosome analysis using karyotyping and bicolor FISH were carried out for two Maackia species (M. fauriei and M. amurensis) found in Korea. The somatic metaphase chromosome number was 2n = 2x = 18 in both, and the size of these chromosomes ranged from 3.58 to $5.82{\mu}m$. The chromosome complements consisted of two pairs of metacentric (chromosomes 1 and 7), four pairs of submetacentrics (chromosomes 4, 6, 8 and 9) and three pairs of subtelocentrics (chromosomes 2, 3 and 5) in M. fauriei but, chromosomes 4 (subtelocentric) and 7 (submetacentric) of M. amurensis have different morphology. Using bicolor FISH, a pair of 45S rDNA loci were observed for both M. fauriei and M. amurensis, but the number and site of the 5S rDNA signal were different in the two species. M. fauriei has two pairs of 5S signals on chromosomes 7 and 8 but, M. amurensis has four paris on chromosomes 3, 4, 7 and 7. Hence, the 5S rDNA is a useful FISH for Maackia species.

MaxR(M) AND ZARISKI TOPOLOGY

  • ANSARI-TOROGHY, H.;KEIVANI, S.;OVLYAEE-SARMAZDEH, R.
    • Honam Mathematical Journal
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    • v.28 no.3
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    • pp.365-376
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    • 2006
  • Let R be a commutative ring and let M be an R-module. Let X = $Spec_R(M)$ be the prime spectrum of M with Zariski topology. In this paper, by using the topological properties of X, we will obtain some conditions under which $Max_R(M)=Spec_R(M)$.

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Clinical Analysis of 102 Cases of Open Heart Surgery (개심수술 102례 의 임상적 고찰)

  • 김형묵
    • Journal of Chest Surgery
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    • v.14 no.3
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    • pp.235-240
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    • 1981
  • A total of 102 patients who had an Open Heart Surgery from April 1976 to July 1981 were reviewed. 55 paeitnts were congenital heart disease and 47 patients were acquired heart disease. Among SS patients of congenital heart disease, 18 T 0 F, 18 V S D, 8 A S D, and each one case of l\ulcorner 0 R V, Truncus arteriosus, Ebstein anomaly, Single ventricle, P D A, P 5, A S D + P 5, E C D, V 5 D + P D A, A - P window, D C R V were noted respectively. In 47 patients of acquired heart disease and one Ebstein patient, 46 prosthetic values were implanted: 17 had M V R, 4 had A V R, 2 had M V R + A V R, and 4 had M V R + T V R and one T V R. The operative mortality was 8.S% in acquired heart disease and 17% in congenital heart disease. The follow up period was between 6 months and 6 years. There were 3 cases of late mortality in acquired heart disease and one case in congenital heart disease.

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A REMARK ON MULTIPLICATION MODULES

  • Choi, Chang-Woo;Kim, Eun-Sup
    • Bulletin of the Korean Mathematical Society
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    • v.31 no.2
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    • pp.163-165
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    • 1994
  • Modules which satisfy the converse of Schur's lemma have been studied by many authors. In [6], R. Ware proved that a projective module P over a semiprime ring R is irreducible if and only if En $d_{R}$(P) is a division ring. Also, Y. Hirano and J.K. Park proved that a torsionless module M over a semiprime ring R is irreducible if and only if En $d_{R}$(M) is a division ring. In case R is a commutative ring, we obtain the following: An R-module M is irreducible if and only if En $d_{R}$(M) is a division ring and M is a multiplication R-module. Throughout this paper, R is commutative ring with identity and all modules are unital left R-modules. Let R be a commutative ring with identity and let M be an R-module. Then M is called a multiplication module if for each submodule N of M, there exists and ideal I of R such that N=IM. Cyclic R-modules are multiplication modules. In particular, irreducible R-modules are multiplication modules.dules.

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