• The Bulletin of The Korean Astronomical Society
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• v.35 no.2
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• pp.38.1-38.1
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• 2010

We present the results of the survey for submillimeter galaxies in the MS0451 (04h 54m 10.8s, -03d 00m 57.0s) at z = 0.55 and PKS1138-262 (11h 40m 48.25s, -26d 29m 10.1s) at z = 2.16 with the 1.1mm bolometer array AzTEC at the James Clerk Maxwell Telescope. The samples were centered on a prominent large-scale structure overdensity. Submillimeter galaxies seem to be starburst galaxies at high redshift ($z\;\geq\;1$) with high starformation rates ($\sim1000M\odot\;yr^{-1}$) or active galactic nuclei (AGN). We have obtained AzTEC images using the AzTEC data reduction pipeline with the IDL language. Through a bayes' theorem, we determined the extragalaxy catalogue, containing the false-detection rate, completeness, flux deboosting correction, and the source positional uncertainty in this region. We compared the catalogue with HST, DSS, 2MASS observations.

• Proceedings of the Korean Vacuum Society Conference
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• 1998.02a
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• pp.133-133
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• 1998

In the thin film alloy formation of the transition metals ion-beam-mixing technique forms a metastable structure which cannot be found in the arc-melted metal alloys. Sppecifically it is well known that the studies about the electronic structure of ion-beam-mixed alloys pprovide the useful information in understanding the metastable structures in the metal alloy. We studied the electronic change in the ion-beam-mixed ppt-Ct alloys by XppS and XANES. These analysis tools pprovide us information about the charge transfer in the valence band of intermetallic bonding. The multi-layered films were depposited on the SiO2 substrate by the sequential electron beam evapporation at a ppressure of less than 5$\times$10-7 Torr. These compprise of 4 ppairs of ppt and Cu layers where thicknesses of each layer were varied in order to change the alloy compposition. Ion-beam-mixing pprocess was carried out with 80 keV Ae+ ions with a dose of $1.5\times$ 1016 Ar+/cm2 at room tempperature. The core and valence level energy shift in these system were investigated by x-ray pphotoelectron sppectroscoppy(XppS) pphotoelectrons were excited by monochromatized Al K ａ(1486.6 eV) The ppass energy of the hemisppherical analyzer was 23.5 eV. Core-level binding energies were calibrated with the Fermi level edge. ppt L3-edge and Cu K-edge XANES sppectra were measured with the flourescence mode detector at the 3C1 beam line of the ppLS (ppohang light source). By using the change of White line(WL) area of the each metal sites and the core level shift we can obtain the information about the electrons pparticippating in the intermetallic bonding of the ion-beam-mixed alloys.

• Health Policy and Management
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• v.25 no.2
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• pp.97-106
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• 2015

Background & Methods: The purpose of this research is to estimate the efficiency of the pharmaceutical firms and the determinants of their efficiency. Stochastic frontier analysis(SFA) and panel study are applied to the data of 60 domestic pharmaceutical firms from 2006 to 2012. Results & Conclusion: First, the result of the stochastic frontier analysis shows that overall efficiency of the pharmaceutical firms is increasing as time goes by. However, if firms are classified by the scale, the larger firms show more efficiency and if classified by the degree of innovativeness, the innovative firms show more efficiency compared to the non-innovative firms. This evidences show that the scale and R&D investment have significant relationships with the efficiency of the pharmaceutical firms. Therefore, it is necessary to increase the national level of investment for the fundamental researches to vitalize R&D of the new drugs. Second, the result of estimation of the determinants of efficiency shows that the firms with larger sales promotion expenses and entertainment expenses have less efficiency compared to the other firms. This can be explained by the structural characteristics of the small generic pharmaceutical firms. Therefore, the government had better make the pharmaceutical firms to reduce sales promotion and entertainment expenses and increase R&D expenses by introducing systems such as global budgeting system on medicine or reference pricing system.

• CELLMED
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• v.2 no.3
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• pp.28.1-28.4
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• 2012

There were no studies available measuring the ability to follow instructions for meditation. Hence, the present study was planned to assess the ability to follow instructions for the four mental states viz., cancalata (random thinking), ekagrata (non-meditative concentration), dharana (focused meditation) and dhyana (defocused meditation or effortless meditation) described in yoga texts. Sixty male volunteers with ages ranging from 18 to 31 years (group mean age ${\pm}$ S.D., $22.78{\pm}2.73$) participated in the study. They were assessed using a visual analog scale immediately after each of the four states on four different days. The results showed that following dharana, scores on the visual analog scale were significantly lower compared to those related to cancalata, ekagrata and dhyana. Hence, dharana is the most difficult of the four states.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.220-224
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• 2005

The technology trend of Flat Panel Display (FPD) equipments have been demanded that there are compact and multi-function. Therefore, nano/micro scale patterned on polymeric materials of Back Light Unit (BLU) in Liquid Crystal Display (LCD) that has been investigated. This paper describes a series of Horizontal Type Micro Tensile Tester that were carried out to investigate the load strain distance performance of typical polymeric material sheets. The polymeric materials film that micro size shaped specimens for tensile test are used by Cold-Isostatic-Press (CIP). Test equipment is Horizontal type Micro Tensile Tester that is presented to measure the micro scale mechanical property of thin film for FPD. This paper presents which easy testing tools measure for micro patterned on polyethylene (PET) specimens.

• Journal of ILASS-Korea
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• v.8 no.3
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• pp.27-32
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• 2003

It is important to improve the efficiency of the existing small scale burner which used in agricultural product dry system and gardening dry system. In order to economize fuel Consumption and decrease the exhaust emission especially $CO_2$, the better design for the small scale burner is needed. Spray characteristics are the essential element for the design. Macroscopic spray characteristics such as spray angle and breakup length were measured. SMD which is contained the Microscopic spray characteristics was measured too. SMD was measured at 8mm, I2mm, I6mm downstream of the nozzle tip for both Hago and Danfoss nozzles by the Malvern Particle Sizer.

• 한국전산유체공학회:학술대회논문집
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• 2010.05a
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• pp.501-504
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• 2010

In this study, fire behavior for subway coach fire in the 1/10 reduced scale model is analyzed using numerical analysis method (FDS). The size of the reduced model coach is 1.9 m long, 0.290 m high and 0.235 m. The simulation is carried out only one-sided four doors of the coach are opened. A fire source is the n-heptane pool fire with a mean heat release rate 2.33 kW. Smoke temperature, heat release rate and mass loss rate for the model are calculated.

• Steel and Composite Structures
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• v.46 no.2
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• pp.253-261
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• 2023

The goal of this paper is to investigate dynamic responses of simply-supported laminated micro beams under moving load. In the considered micro-scale problem, the modified coupled stress theory which includes the length scale parameter is used. The governing equations of problem are derived by using the Lagrange procedure. In the solution of the problem the Ritz method is used and algebraic polynomials are used with the trivial functions for the Ritz method. In the solution of the moving load problem, the Newmark average acceleration method is used in the time history. In the numerical examples, the effects of stacking sequence of laminas, fibre orientation angles and the length scale parameter on the dynamic responses of laminated micro beams are examined and discussed.

• Molecular & Cellular Toxicology
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• v.5 no.4
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• pp.346-353
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• 2009

Drug metabolism is a critical determinant of the therapeutic and adverse effects of many psychotropic drugs. The metabolism depends on the pharmacokinetics of a drug, which includes its absorption, distribution, and elimination. Psychotropic drugs are metabolized mainly by cytochrome P450 (CYP) enzymes; about 20 of these enzymes exist and they are often responsible for the rate-limiting step of drug metabolism. CYP2D6 is the best-characterized P450 enzyme that exhibits polymorphism in humans. This study determined the relationship between the CYP2D6*10 (P34S) polymorphism and the response to mirtazapine in 153 Koreans with major depressive disorder (MDD). The genotype frequencies were compared using logistic regression analysis, and between-genotype differences in the decrease in the 21-item Hamilton Depression (HAMD21) score over the 12-week treatment period were analyzed using a linear regression analysis. The proportion of remitters was lower in patients with MDD possessing the S allele than in P allele carriers after 2 weeks of mirtazapine treatment. Similarly, the reductions in the HAMD21 and Clinical Global Impression (CGI) scores in S allele carriers were smaller than those in patients with the P allele after 2 weeks of mirtazapine treatment. In the analysis of depression symptoms, the sleep and delusion scores had smaller reductions in S allele carriers. Based on the Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS), the psychic adverse effects of mirtazapine were associated with CYP2D6 P34S, while weight gain was not. These results suggest that CYP2D6 P34S affects the outcome of mirtazapine treatment in patients with MDD, and that this polymorphism may be a good genetic marker for predicting the clinical outcome of mirtazapine treatment.

• Nutrition Research and Practice
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• v.14 no.1
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• pp.12-19
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• 2020

BACKGROUND/OBJECTIVES: Vitamin D is a pleiotropic hormone that affects various body organ systems. We evaluated the prevalence of a vitamin D deficiency (VDD) and its potential role in the clinical condition of critically ill Korean children. SUBJECTS/METHODS: Patients under 18 years old with a 25(OH) vitamin D measurement on the first day of PICU admission were included from among the children admitted to the pediatric intensive care unit (PICU) of our tertiary children's hospital between October 2017 and January 2019. RESULTS: A total of 172 pediatric patients were enrolled. The mean 25(OH) vitamin D level was 17.5 ± 12.8 ng/mL. There was a 65.1% prevalence of VDD (25(OH) vitamin D level < 20 ng/mL). VDD was associated with age at PICU admission, gastrointestinal/hepatobiliary disorders, International Society of Thrombosis and Hemostasis disseminated intravascular coagulation (ISTH DIC) score, pediatric multiple organ dysfunction syndrome (pMODS) score and with several laboratory test findings including hemoglobin, platelet, C-reactive protein, serum albumin, total bilirubin, prothrombin time, and anti-thrombin III levels. Most of these parameters also showed significant linear correlations with the 25(OH) vitamin D level (P < 0.05). However, no statistically meaningful association was found between VDD and other clinical conditions such as the need for a mechanical ventilator, requirement for vasoactive drugs, duration of the PICU and hospital stays, or PICU mortality. CONCLUSION: There is a high prevalence of VDD in critically ill Korean children. There were significant associations between the 25(OH) vitamin D level and gastrointestinal/hepatobiliary disorders, the pMODS score and with coagulation related factors. Further large-scale studies with more specific subgroup analyses are required to more precisely assess the clinical implications of VDD in critically ill pediatric patients.