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Immuno-Electron Microscopic Studies on the Localization of Serotonin and Somatostatin in the Optic Lobes of Cephalopods (Todarodes pacificus and Octopus minor) Inhabiting the Korean Waters (한국 연근해산 두족류 (Todarodes pacificus and Octopus minor) 시엽 (Optic lobe)내 Serotonin 및 Somatostatin의 분포에 관한 면역전자현미경적 연구)

  • Chang, Nam-Sub;Han, Jong-Min;Kim, Sang-Won;Lee, Kwang-Ju;Hwang, Sun-Jong;Lee, Jung-Chan
    • Applied Microscopy
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    • v.32 no.3
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    • pp.247-255
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    • 2002
  • In this study, we carried out immunostaining and immunogold labeling with antibodies to serotonin and somatostatin to examine the characteristics and functions of the neurons that secrete neurotransmitters in optic lobes of Todarodes pacificus and Octopus minor. As a result of immunostaining with anti-somatostatin, the nerve cells of Todarodes pacificus reacted as similar to the anti-serotonin, but in Octopus minor, only large cells in the outer granule cell layer reacted positively. In the immunogold labeling with anti-serotonin, the nerve cells in the inner grande cell layer and medulla of Todarodes pacificus reacted strongly, 30 gold particles being labeled per $0.5{\mu}m^2$ of the cytoplasm. However, in Octopus minor, only 17 gold particles were labeled, which stated a weak reaction. On the other hand, in the anti-somatostatin case, the nerve cells in the outer and inner granule cell layers and medulla of Todarodes pacificus showed strong reaction, 30 gold particles being labeled per $0.5{\mu}m^2$ of the cytoplasm while the nerve cells in the outer granule cell layer of Octopus minor reacted weakly, about 3 gold particles being labeled per the equivalent area. As a result of immunostaining and immunogold labeling with two types of antibodies to each part of the optic lobes, we found that the reactive nerve cells were distributed differently in the two species. In particular, the degree of reactivity to the immunostaining and immunogold labeling appeared stronger in Todarodes pacificus than in Octopus minor.

On the Summability of Infinite Series and Hüseyin Bor (무한급수의 총합 가능성과 후세인 보르에 관하여)

  • Lee, Jung Oh
    • Journal for History of Mathematics
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    • v.30 no.6
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    • pp.353-365
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    • 2017
  • In general, there is summability among the mathematical tools that are the criterion for the convergence of infinite series. Many authors have studied on the summability of infinite series, the summability of Fourier series and the summability factors. Especially, $H{\ddot{u}}seyin$ Bor had published his important results on these topics from the beginning of 1980 to the end of 1990. In this paper, we investigate the minor academic genealogy of teachers and pupils from Fourier to $H{\ddot{u}}seyin$ Bor in section 2. We introduce the $H{\ddot{u}}seyin$ Bor's major results of the summability for infinite series from 1983 to 1997 in section 3. In conclusion, we summarize his research characteristics and significance on the summability of infinite series. Also, we present the diagrams of $H{\ddot{u}}seyin$ Bor's minor academic genealogy from Fourier to $H{\ddot{u}}seyin$ Bor and minor research lineage on the summability of infinite series.

Flow Field Measurement in Catalytic Converter-Comparison with Computational Fluid Dynamics Analyses (촉매 변환기의 내부 유동장 측정-CFD 해석과 비교)

  • Yoo, Seoung-Chool;Jang, Sung-Kuk
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.38 no.3
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    • pp.197-202
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    • 2014
  • The efficiency of a catalytic converter depends on the flow distribution across a system's chemically active substrate. If irregularities or non-uniform flow patterns exist, the system's conversion efficiency decreases, whereas the manufacturing cost increases. Therefore, it is important to analyze the internal flow of a catalytic converter. In this study, flow pattern measurements along the minor axis were recorded at the mid and exit planes of a ceramic honeycomb catalytic converter at flow rates of 37.8 l/s and 94.4 l/s. Flow distributions of the measurement plans were compared with an automotive company's computed velocity profiles. Measurements along the minor axis showed uneven velocity profiles. The ${\upsilon}$-velocity components between the honeycomb bricks were small but somewhat erratic opposite the intake side of the converter, however, they became flatter in measurements recorded near the intake entrance. For almost all velocity values, the computer model suggested velocities greater than the measured values.

Electrophoresis Techniques for Identification of Callus Induced from Pinella ternata (Thunb.) Breit 1. Analysis of protein and Enzymes of Callus Induced from Pinella ternata (Thunb.) Breit (기내 배양된 반하의 전기영동에 의한 생약학적 연구 1. 전기영동법에 의한 반하 Callus의 단백질 및 효소분석)

  • Choi, Jung-Sik;Ryu, Jeom-Ho;Park, Hak-Bong;Kim, Hyung-Moo
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.33 no.2
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    • pp.122-125
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    • 1988
  • A comparative electrophoretic study on protein and several important enzymes of calli induced from stem, intercostal area and minor vein area were conducted in Pinella ternata (Thunb.) Breit. Soluble protein band patterns of calli induced from stem, intercostal area and minor vein area were distinctly different from those of the corresponding plant parts. Esterase isozyme patterns of calli induced from stem, intercostal area and minor vein area were different from those of the corresponding plant parts. Glutamate oxalo-acetate transaminase isozyme patterns of calli grown for 4 weeks induced from 3 plant parts were similar to those of the corresponding plant parts. But a high molecular weight isozyme band appeared in the calli grown for 8 weeks. Alow molecular weight isozyme band disappeared on the peroxidase isozyme patterns of calli grown for 4 weeks appeared on those of the corresponding plant parts.

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Research for the Legal Protection System of Minor Actors and Actresses -Focused on the Analysis of Popular Culture Art Industrial Development Act- (우리나라 청소년 연기자 보호 제도에 관한 고찰 -2014년 시행 '대중문화예술산업발전법' 분석을 중심으로-)

  • Kim, Jeong-Seob
    • The Journal of the Korea Contents Association
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    • v.15 no.1
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    • pp.86-94
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    • 2015
  • This study is carried out to critically explore the direction of the improvement of the protection clauses of minor artists which is the core of Popular Culture Art Industrial Development Act enforced from July 29, 2014. The analysis shows that the law accepted the social issues such as the prevention of procuring minor prostitution, slave contracts(unfair long-term contracts), and third party's profit-extortion. However, the law missing or not specifically stated about age-based differential enforcement of work hours, dangerous acting scenes shouldn't be forced to minors, right to sleep, health, and study, as well as the penalty regulations in violation of each clause. Consequently, the Act's revision and supplementation is necessary to fully meet above insufficiencies referring to foreign practices.

The Effects of Volume Ratio and Shape on the Formation of Adiabatic Shear Band in WHA (텅스텐 중합금의 부피분율, 입자형상에 따른 단열전단밴드 형성 연구)

  • 이승우;송흥섭;문갑태
    • Transactions of Materials Processing
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    • v.11 no.8
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    • pp.682-690
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    • 2002
  • The formation of adiabatic shearband in tungsten heavy alloys(WHA) was studied in this investigation. Five prismatic specimens were loaded by high velocity impacts and treated as plane strain problems. To find out the effect of particle's volume ratio, specimens containing 81%, 93% and 97% volume percents of tungsten particles were used. Also the effects of particle's geometry and size on the formation of shearband were studied for 81% volume percent alloys by small size particle model, large size particle model and undulated particle models, and the results were discussed.be used to diagnose the causes of necking and fracture in industrial practice and to investigate whether these defects were caused by material property variation, changes in lubrication, or incorrect press settings. In non-axisymmetric deep drawing, three modes of forming regimes are found: draw, stretch, plane strain. The stretch mode for non-axisymmetric deep drawing could be defined when the major and minor strains are positive. The draw mode could be defined when the major strain is positive and minor strain is negative, and plane strain mode could be defined when the major strain is positive and minor strain is zero. Through experiments the draw mode was shown on the wall and flange are one of a drawn cup, while the plane strain and the stretch mode were on the punch head and the punch corner area respectively, We observed that the punch load of elliptical deep drawing was decreased according to increase of die corner radius and the thickness deformation of minor side was more large than major side.

Fermentative transformation of ginsenosides by a combination of probiotic Lactobacillus helveticus and Pediococcus pentosaceus (프로바이틱스 Lactobacillus helveticus와 Pediococcus pentosaceus의 조합에 의한 진세노사이드의 발효적 형질전환)

  • Palaniyandi, Sasikumar Arunachalam;Le, Bao;Kim, Jin-Man;Yang, Seung Hwan
    • Korean Journal of Microbiology
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    • v.54 no.4
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    • pp.436-441
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    • 2018
  • Ginseng are native traditional herbs, which exhibit excellent pharmacological activities. Probiotic Lactobacillus helveticus KII13 and Pediococcus pentosaceus strain KID7 were used for ginsenoside transformation by fermenting crude ginseng extract to enhance minor gisenoside content. Thin-layer chromatography (TLC) analysis of fermented ginseng extract showed that the minor ginsenosides Rg3, Rh1, and Rh2 were main products after 5 days of fermentation. HPLC analysis was performed to quantify the major and minor ginsenosides. The Rg3 peak appeared on the 3rd day while the appearance of Rh2 peak and Rh1 peak were observed on the 5th day. The co-culture of L. helveticus KII13 and P. pentosaceus KID7 converted major ginsenosides (Rb1 and Rg1) into minor ginsenosides (Rg3, Rh2, and Rh1).

Minor alleles in the FTO SNPs contributed to the increased risk of obesity among Korean adults: meta-analysis from nationwide big data-based studies

  • Oh Yoen Kim;Jihyun Park;Jounghee Lee;Cheongmin Sohn;Mi Ock Yoon;Myoungsook Lee
    • Nutrition Research and Practice
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    • v.17 no.1
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    • pp.62-72
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    • 2023
  • BACKGROUND/OBJECTIVES: Many studies have revealed an association between fat mass and the obesity-related gene (FTO) and obesity. On the other hand, no meta-analysis was conducted with data from only Koreans. Therefore, this study performed a meta-analysis using Korean data to provide evidence for the association between FTO single nucleotide polymorphisms (SNPs) and the risk of obesity among Korean adults. SUBJECT/METHODS: Meta-analysis was finally conducted with data extracted from seven datasets of four studies performed on Korean adults after the screening passed. Five kinds of FTO SNPs (rs9939609, rs7193144, rs9940128, rs8050136, and rs9926289) were included, and the relationship between FTO SNPs and body mass index (BMI) was investigated using linear regression with an additive model adjusted for covariants, such as age, sex, and area. RESULTS: The minor alleles of FTO SNPs were associated with increased BMI (odds ratio [OR], 1.31; 95% confidence interval [CI], 1.21-1.42). In sub-group analysis, FTO rs9939609 T>A was significantly associated with BMI (OR, 1.23; 95% CI, 1.06-1.42). The other FTO SNPs together were significantly associated with BMI (OR, 1.37; 95% CI, 1.25-1.49). The publication bias was not observed based on Egger's test. CONCLUSIONS: This meta-analysis showed that minor alleles in the FTO SNPs were significantly associated with an increased BMI among Korean adults. This meta-analysis is the first to demonstrate that minor alleles in the FTO SNPs contribute significantly to the increased risk of obesity among Korean adults using data from a Korean population.

Correction of Minor-Form and Microform Cleft Lip Using Modified Muscle Overlapping with a Minimal Skin Incision

  • Kim, Min Chul;Choi, Dong Hun;Bae, Sung Gun;Cho, Byung Chae
    • Archives of Plastic Surgery
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    • v.44 no.3
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    • pp.210-216
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    • 2017
  • Background In treating minor-form or microform cleft lip, obtaining an optimal result is a challenge because of the visible scarring caused by traditional surgery. We present a refined method using muscle overlapping with a minimal skin incision in patients younger than 3 years, a group characterized by thin muscle. Methods The surgical technique involves restoration of the notched vermillion using Z-plasty, formation of the philtral column using overlapping of an orbicularis oris muscle flap through an intraoral incision, and correction of the cleft lip nasal deformity using a reverse-U incision and V-Y plasty. A single radiologist evaluated ultrasonographic images of the upper lip. Results Sixty patients were treated between September 2008 and June 2014. The age at the time of operation ranged from 6 to 36 months (mean, 26 months). The follow-up period ranged from 8 to 38 months (mean, 20 months) in minor-form cases and from 14 to 64 months (mean, 37 months) in microform cases. A notched cupid's bow was corrected in 10 minor-form cases and 50 microform cases. Ultrasonographic images were obtained from 3 patients with minor-form cleft lip and 9 patients with microform cleft lip 12 months after surgery. The average muscle thickness was 4.5 mm on the affected side and 4.1 mm on the unaffected side. Conclusions The advantages of the proposed procedure include the creation of an anatomically natural philtrum with minimal scarring. This method also preserves the continuity and function of the muscle and provides sufficient augmentation of the philtral column and nostril sill.

Ultimate Strength Analysis of Stiffened Plate with Minor Collision Damage (작은 충돌손상을 가진 보강판의 최종강도 해석)

  • Lee, Tak-Kee;Rim, Chae-Whan
    • Journal of Ocean Engineering and Technology
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    • v.21 no.4
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    • pp.34-37
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    • 2007
  • The safety of ships is one of the most important concerns in terms of the environment and human life. A ship in bad condition is likely to be subject to accidents, such as collision and grounding. When a ship has minor collision damages in the form of circle or ellipse, its ultimate strength will be reduced. It is important to evaluate the reduction ratio of a ship's ultimate strength that results from damages. The strength reduction of a plate with a cutout in the form of hole has been treated by many researchers. A closed-form formula for the reduction of ultimate strength of a plate, considering the effect of several forms of cutout, has been suggested. However, the structure of ships is composed of plates and stiffeners so-called stiffened plates and it is likely that plates and stiffeners will be damaged together in collisions. This paper investigates the effect of minor collision damages on the ultimate strength of a stiffened plate by using numerical analysis. For this study, the deformed shape of minor collision damages on a stiffened plate was made by using a contact algorithm and was used as the initial shape for ultimate stress analysis. Then, a series of nonlinear FE analyses was conducted to investigate the reduction effects on the ultimate strength of the stiffened plate. The boundary conditions were simply supported at all boundaries, and the tripping of stiffener was neglected. The results are presented in the form of reduction ratio between the ultimate strength of an original, intact stiffened plate and that of a damaged stiffened plate.