• Journal of Ginseng Research
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• 제38권3호
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• pp.194-202
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• 2014

Background: Ginsenosides, the major ingredients of Panax ginseng, have been studied for many decades in Asian countries as a result of their wide range of pharmacological properties. The less polar ginsenosides, with one or two sugar residues, are not present in nature and are produced during manufacturing processes by methods such as heating, steaming, acid hydrolysis, and enzyme reactions. $^1H$-NMR and $^{13}C$-NMR spectroscopic data for the identification of the less polar ginsenosides are often unavailable or incomplete. Methods: We isolated 21 compounds, including 10 pairs of 20(S) and 20(R) less polar ginsenosides (1-20), and an oleanane-type triterpene (21) from a processed ginseng preparation and obtained complete $^1H$-NMR and $^{13}C$-NMR spectroscopic data for the following compounds, referred to as compounds 1-21 for rapid identification: 20(S)-ginsenosides Rh2 (1), 20(R)-Rh2 (2), 20(S)-Rg3 (3), 20(R)-Rg3 (4), 6'-O-acetyl-20(S)-Rh2 [20(S)-AcetylRh2] (5), 20(R)-AcetylRh2 (6), 25-hydroxy-20(S)-Rh2 (7), 25-hydroxy-20(S)-Rh2 (8), 20(S)-Rh1 (9), 20(R)-Rh1 (10), 20(S)-Rg2 (11), 20(R)-Rg2 (12), 25-hydroxy-20(S)-Rh1 (13), 25-hydroxy-20(R)-Rh1 (14), 20(S)-AcetylRg2 (15), 20(R)-AcetylRg2 (16), Rh4 (17), Rg5 (18), Rk1 (19), 25-hydroxy-Rh4 (20), and oleanolic acid 28-O-b-D-glucopyranoside (21).

• 약학회지
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• 제35권5호
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• pp.432-437
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• 1991

A mixture of 20(R)- and 20(S)-ginsenoside Rg$_{3}$ was obtained under mild acidic hydrolysis from protopanaxadiol saponins, ginsenosides Rb$_{1}$, Rb$_{2}$, Rc and Rd. The product was acetylated to give the peracetates, which were further converted into 20(R)-ginsenoside Rg$_{3}$, 20(S)-ginsenoside Rg$_{3}$, 20(R)-ginsenoside Rh$_{2}$ and 20(S)-ginsenoside Rh$_{2}$ by the direct alkaline treatment depending upon two kinds of temperature conditions respectively. The structure and physicochemical properties of a prosapogenin, 20(R)-ginsenoside Rh$_{2}$, were investigated.

• 한국생활과학회지
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• 제12권5호
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• pp.777-786
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• 2003

The purpose of this study was to compare the perception of men's lower body shape in the 60s with that in the 20s. On hundred and seven men in the 60s and 178 men in the 20s participated in the survey and measurements. The results were as follows : 1. It was perceived that men in the 60s had broader girth but lighter weight than men in the 20s. The research revealed that men in the 60s was more satisfied with their lower body shape than men in the 20s. 2. It was also found that the ideal size of men in the 60s was broader in the girth of their waist and hip, shorter in their height, and lighter in their weight compared to men in the 20s. 3. It showed a difference in the satisfaction with their body shape between men in the 60s and the 20s. The satisfaction with their lower body shape of men in the 60s was more affected by their perception than by their real measured size. On the other hand, the satisfaction of men in the 20s was affected by their perception as much as by their measured size. 4. If we look at the perception and satisfaction in relation with their body types, we found that there was a difference in the girth of their waist, abdomen, hip, and weight depending on their body types. And men in the 20s showed greater differences in their perception and satisfaction depending on their body types, compared to men in the 60s. 5. The measured size of men in the 20s had greater differences depending on their body types than that of men in the 60s. On the contrary, the ideal size of men in the 60s had greater differences than that of men in the 20s.

• Journal of Ginseng Research
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• 제15권3호
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• pp.188-191
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• 1991

The mild hydrolysis of ginsenosie Re with 50% acetic acid gave a prosapogenin mixture, 20(R)- and 20(S)-ginsenoside Rg2. The products were acetylated to give the peracetates, which were further converted into 20(R)- and 20(S)-ginsenoside Rh1 by the alcoholic alkaline treatment.

• 감성과학
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• 제13권3호
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• pp.485-492
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• 2010

이 논문에서는 20대와 60대를 얼굴의 측정치와 시각적 분석을 통해 얼굴의 비율과 불균형을 분석하였다. 얼굴폭과 얼굴길이의 비율이 20대는 1 : 1.34, 60대는 1 : 1.39로 나타나 60대 여성의 얼굴길이가 길며, 상안 부길이, 중안부길이, 하안부길이의 비율에서 20대는 0.85 : 1 : 1로 중안부길이와 하안부의 길이가 같은 반면, 60대는 0.84 : 1 : 1.06으로 하안부길이가 길고 상안부길이가 짧다. 얼굴의 균형감은 $2^{\circ}$이상의 심한 불균형인 경우 눈초리각도가 20대에서 8%, 60대에서 13%, 코각도가 20대에서 11%, 60대에서 29%, 구각각도에서 20대가11%, 60대에서 40%로 나타나, 60대의 불균형이 심각하게 나타났다. 이상과 같이 20대에 비해 60대의 얼굴이 전체적으로 길며, 그중에서도 하안부가 길게 나타난 것은 노화로 인해 얼굴이 변화됨을 알 수 있다. 또한 얼굴의 불균형이 20대에 비해 60대에서 많이 나타남을 알 수 있다.

• 한국재료학회지
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• 제4권6호
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• pp.704-709
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• 1994

Crystal Structure and Magnetic Properties of $(LaS)_xCrS_2(x \approx 1.20$)가 1273K에서 $La_S_3$ , Cr, S의 혼합물의 반응으로부터 합성되었다. $(LaS)_xCrS_2( x\approx 1.20$)의 XRD회절 pattern은 monoclinic의 LaS-부격자, triclinic의 $CrS_{2}$-부격자와 그들의 초격자로서 해석되었다. 부격자의 온도의존성을 저온에서 X-선 회절분석으로 조사하였다. 77K~실온의 온도역에서 $(LaS)_xCrS_2(x \approx 1.20$)의 자기자화율을 Faraday balance법으로 측정하였다. $(LaS)_xCrS_2(x \approx 1.20$)은 실온 $\sigma$ -H plot에서 paramagnetic한 거동을 나타내었다. 관측된 유효자기 moment($\mu_{eff}$)는 $Cr^{3+}$을 spin-only에 의한 것과 $La^{3+}$을 spin-only와 orbital에 의한 것으로 계산할 경우 잘 일치되었다.

• 정신신체의학
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• 제11권1호
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• pp.77-88
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• 2003

연구목적: 1985년 Taylor 등이 발표한 TAS는 감정표현불능증을 측정하는 도구로서 1992년 TAS-20으로 개정되어 여러 나라에서 신뢰도와 타당도가 검증되었다. 본 연구는 혼재되어 쓰이고 있는 세 가지 TAS 한국판 감정표현불능증 척도를 비교하여 가장 신뢰도와 타당도가 높은 척도를 통일하여 사용하고자 시도되었다. 첫 번째 척도는 1996년 이양현 등이 개발한 것{이후 TAS-20K(1996)}이다. 두 번째 척도는 위 연구에서 "어떤 문제를 묘사하기보다는 분석하는 편이다"라고 직역한 5번 항목의 결과가 예측치와 상반되어 '분석하다'라는 단어에 대한 우리나라와 서양의 문화적 견해 차이를 고려하여 5번 문항을 수정 제안한 것{이후 TAS-20K(2003)}으로서, 타당도와 신뢰도의 호전을 검증하지 않은 것이다. 세 번째 척도는 1997년 신현균과 원호택이 TAS-20을 번역한 것(이후 S-TAS)으로 20항목의 원래 항목 수를 23개로 수정 번역한 특성을 지니고 있다. 방 법: 의학과 학생 408명을 대상으로 세 가지 척도의 서로 다른 항목, 즉 TAS-20K(1996)의 20항목, TAS-20K(2003)의 수정 제안된 1항목, S-TAS의 23항목을 무작위로 배열하여 구성된 하나의 척도를 사용하여 검사를 시행하였다. 세 가지 척도의 신뢰도를 비교하기 위해 내적 일치도(Cronbach $\alpha$ coefficients)를 구하였고 타당도를 비교하기 위해 확증적 요인 분석(confirmatory factor analysis)을 실시하였다. 결 과: TAS-20K(2003)은 TAS-20K(1996)보다 내적 일치도가 호전되었다. TAS-20K(2003)과 S-TAS는 모두 원척도의 세 요인 구조를 재현하였고, 우수한 내적 일치도와 받아들일 만한 타당도를 보여 주었다. 그러나 S-TAS는 19번 항목이 요인 2와 상관성이 낮게 나타났고, 이전 연구에서와 같이 2번 항목과 요인 1간의 상관성이 재현되지 않아 본래 요인 2에 속한 19번 항목을 요인 1에도 포함시키는 것이 타당하지 않았다. 결 론: TAS-20K(2003)과 S-TAS는 모두 원본 TAS-20의 번역판으로서 우수한 타당도와 받아들일만한 신뢰도를 보였다. 그러나 TAS-20K(2003)은 원본과 동일한 항목 수와 구조, 동일한 점수 체계를 유지하고 있으며 TAS-20은 이미 15개 이상의 언어로 번역되어 있는 도구이나, S-TAS는 항목 수 및 점수 체계, 요인 구조를 원본 TAS-20과 다르게 변형시켜 국제적인 비교 연구를 위해서는 제한점이 있다고 하겠다. 따라서 향후 감정표현불능증의 국내 연구에서 TAS-20K(2003), 즉 TAS-20K를 사용하는 것이 더 적절할 것으로 제안한다.

• Journal of Ginseng Research
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• 제19권1호
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• pp.45-50
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• 1995

(20S)- and (20R)-protopanaxadiol were prepared from crude ginseng saponin by chemical treatment. The $^{1}H$- and $^{13}C$-NMR signals of these compounds were fully assigned by various NMR techniques such as DEPT, 1H-1H COSY, HMQC, HMBC and NOESY.

• 대한의생명과학회지
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• 제26권3호
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• pp.186-191
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• 2020

This study was designed to investigate the median nerve cross-sectional area of the upper extremity which is the main cause of CTS in the 20s and 30s. The median nerve cross-sectional area (MNC-area) of each part of the upper limb was measured in healthy 20s and 30s females and males without neurological diseases or other diseases. This MNC-area was compared with the hand, wrist, finger, and other body indexes. The research group was divided into 20s female and male groups, and the 30s were also divided into female and male groups. In the comparison between the ages, the hand, and wrist configurations in the 30s were significantly higher than those of the 20s. The mean median nerve cross-sectional area was significantly larger in the male group than in the female group in both 20s and 30s, and it was larger in both men and women than in the 20s. Hand and wrist configurations were also positively correlated with the median nerve cross-sectional area in both 20s and 30s. The median values of hand ratio and wrist ratio were 2.26 and 0.65, respectively. This median value of hand ratio was inversely correlated with the median nerve cross-sectional area. The median nerve cross-area of the 20s was 6.88~7.38 ㎟ in the male group and 5.69~6.99 ㎟ in the female group, respectively. The median nerve cross-area of the 30s was 6.32~8.89 ㎟ in the male group and 6.15~7.17 ㎟ in the female group, respectively. The mean median nerve cross-sectional area was positively correlated with body mass index in both groups. Most of the variables were higher in their 30s than in their 20s.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1993년도 학술대회지
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• pp.74-83
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• 1993

In an attempt toward the synthesis of the difficulty accessible ginseng saponins the four dammarane glycosides identical to the natural $ginsenosides-Rh_2,$ - F2, compound K and chikusetsusaponin - LT8 have been prepared from betulafolienetriol(=dammar-24-ene-$3{\alpha},12{\beta}\;20(S)-triol).\;3-O-{\beta}-D-Glucopyranoside$ of 20(S) - protopanaxadiol $(=ginsenoside-Rh_2)$ have been obtained by the regio - and stereoselective glycosylation of the $12-O-acetyldammar-24-ene-3{\beta},\;12{\beta},$ 20(S)-triol. The 12-ketoderivative of 20(S)-protopanaxadiol has been used as aglycon in synthesis of chikusetsusaponin - LT8. Attempted regio - and stereoselective glycosylation of the less reactive tertiary C - 20 - hydroxyl group in order to synthesize the $20-O-{\beta}-D-glucopyranoside$ of 20(S)-protopanaxadiol(=compound K) using 3, 12 - di - O - acetyldammar - 24 - ene - $3{\beta},12{\beta},20(S)$-trial as aglycon was unsuccessful. Glycosylation of 3, 12 - diketone of betulafolienetriol followed by $NaBH_4$ reduction yielded the $20-O-{\beta}-D-glucopyranoside\;of\;dammar-24-ene-3{\beta},12{\alpha},$ 20(S)-triol, the $12{\alpha}-epimer$ of 20(S) - protopanaxadiol. Moreover, a number of semisynthetic ocotillol - type glucosides, analogs of natural pseudoginsenosides, have been prepared.