• Title/Summary/Keyword: Response reduction

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Ruminal pH pattern, fermentation characteristics and related bacteria in response to dietary live yeast (Saccharomyces cerevisiae) supplementation in beef cattle

  • Zhang, Xiangfei;Dong, Xianwen;Wanapat, Metha;Shah, Ali Mujtaba;Luo, Xiaolin;Peng, Quanhui;Kang, Kun;Hu, Rui;Guan, Jiuqiang;Wang, Zhisheng
    • Animal Bioscience
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    • v.35 no.2
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    • pp.184-195
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    • 2022
  • Objective: In this study we aimed to evaluate the effect of dietary live yeast supplementation on ruminal pH pattern, fermentation characteristics and associated bacteria in beef cattle. Methods: This work comprised of in vitro and in vivo experiments. In vitro fermentation was conducted by incubating 0%, 0.05%, 0.075%, 0.1%, 0.125%, and 0.15% active dried yeast (Saccharomyces cerevisiae, ADY) with total mixed ration substrate to determine its dose effect. According to in vitro results, 0.1% ADY inclusion level was assigned in in vivo study for continuously monitoring ruminal fermentation characteristics and microbes. Six ruminally cannulated steers were randomly assigned to 2 treatments (Control and ADY supplementation) as two-period crossover design (30-day). Blood samples were harvested before-feeding and rumen fluid was sampled at 0, 3, 6, 9, and 12 h post-feeding on 30 d. Results: After 24 h in vitro fermentation, pH and gas production were increased at 0.1% ADY where ammonia nitrogen and microbial crude protein also displayed lowest and peak values, respectively. Acetate, butyrate and total volatile fatty acids concentrations heightened with increasing ADY doses and plateaued at high levels, while acetate to propionate ratio was decreased accordingly. In in vivo study, ruminal pH was increased with ADY supplementation that also elevated acetate and propionate. Conversely, ADY reduced lactate level by dampening Streptococcus bovis and inducing greater Selenomonas ruminantium and Megasphaera elsdenii populations involved in lactate utilization. The serum urea nitrogen decreased, whereas glucose, albumin and total protein concentrations were increased with ADY supplementation. Conclusion: The results demonstrated dietary ADY improved ruminal fermentation dose-dependently. The ruminal lactate reduction through modification of lactate metabolic bacteria could be an important reason for rumen pH stabilization induced by ADY. ADY supplementation offered a complementary probiotics strategy in improving gluconeogenesis and nitrogen metabolism of beef cattle, potentially resulted from optimized rumen pH and fermentation.

Ground Vibration Reduction Technology Using High Damping Polymer Concrete (고 감쇠 폴리머 콘크리트를 활용한 지반진동 저감기술에 대한 연구)

  • Kim, Jeong-Jin;Seok, Won-Gyun;We, Joon-Woo;Ahn, So-Hee
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.25 no.6
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    • pp.154-160
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    • 2021
  • Recently, there have been increasing construction works carried out in urban centers, which are inducing frequent artificial vibration in the vicinity of existing structures due to such construction works. moreover, in case of industrial estates, vibration is induced due to operation of machines in the surrounding areas, thereby causing problems. meanwhile, in case of ordinary concrete that compose structure has low level of damping capability for vibration. accordingly, there are difficulties in blocking a wide range of vibrations delivered to the structures from outside including not only vibrations generated in the structures themselves but also ground vibration. recently, numerous studies are being carried out actively on high-damping system that markedly enhanced the damping performances of structures by utilizing polymer concrete in order to block the vibrations delivered to the structures through ground. therefore, this study compared the performances of polymer concrete with those of ordinary concrete, polyurethane pad and foamed rubber pad in order to review its performances in reducing ground vibration. for this purpose, review of FRF and vibration acceleration as dynamic characteristics was made. after comparative verification on the dynamic characteristics is made when polymer concrete and other aforementioned materials are applied to underground structures, the possibility of application of polymer concrete to structures is reviewed.

Improving the 2022 Revised Science Curriculum: Elementary School "Earth and Universe" Units (2022 개정 과학과 교육과정 개선 방향 고찰 - 초등학교 '지구와 우주' 영역을 중심으로 -)

  • Yu, Eun-Jeong;Park, Jae Yong;Lee, Hyundong
    • Journal of Korean Elementary Science Education
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    • v.41 no.2
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    • pp.173-185
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    • 2022
  • The purpose of this study is to present a reflective review of the earth and universe units from the revised elementary curriculum of 2007-2015 and suggest changes in the 2022 revised curriculum. For this purpose, we conducted an FGI with earth science educators and elementary school teachers regarding the content elements and system, the achievement standards and inquiry activity composition, and the vertical and horizontal curriculum connectivity. Free response and weighted hierarchical analysis items were incorporated into the FGI to ensure logical consistency of the inductively derived improvement. This analysis revealed that the composition of units by grade group had been unevenly distributed among each of the "earth systems" until the 2015 revised curriculum was finalized. Furthermore, the basic concept was still insufficient. We suggest that achievement standards centered on the learning content and skills must state specific scientific core competencies, and inquiry activities should include rigorous critical thinking, student written responses, and student inquiry and analysis. In the hierarchical analysis items, FGI emphasized the inclusion of essential content elements rather than reduction of content elements, understanding-oriented concept learning rather than interest-centered phenomenon learning, basic concept division learning before integration between subjects, and expanding vertical-horizontal connectivity rather than repeating and advancing learning. There is a limit to the generalizing the suggestions proposed in this study to the common opinion of elementary earth science experts. However, since the main vision of the 2022 revised curriculum is to gather opinions through educational entities' participation in a variety of educational subjects, it is suggested that our results should be incorporated as one of the opinions proposed for the 2022 curriculum revision.

Ethylene Gas Indicator for Monitoring Climacteric Fruit Ripening (과일 숙성 에틸렌가스 지시계 기술개발 현황)

  • Shin, Dong Un;Lee, Seung Ju
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.28 no.1
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    • pp.47-53
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    • 2022
  • Recently, intelligent packaging of foods has been increasingly developed in response to the growing interest of consumers in checking food quality. Indicators, an important element in intelligent packaging, change color to detect specific substances or indicate food quality changes. Gas indicators can be built into food packaging to detect volatile substances that are released when food quality changes. Ethylene gas is produced as climacteric fruits ripen. Climacteric fruit ripening results from a rapid increase in ethylene production and respiration. In the case of packaged fruits, the ethylene gas concentration in the headspace is closely related to the ripeness of each fruit variety. If an ethylene gas indicator that can be used in fruit packaging is available, the consumer will be able to eat the fruit at the optimal time. In this paper, the characteristics and pros and cons of the ethylene gas indicators developed so far were analyzed by reviewing various types of indicators such as metal reduction-based indicator, fluorescence-based indicator, pH indicator-based indicator, and liposome-based indicator.

Development of Nanomodified Snow-Melting Concrete Using Low-Temperature Phase-Change Material Impregnated Lightweight Aggregate (저온 상변화 물질 함침 경량골재를 이용한 나노 개질 융설 콘크리트 개발)

  • Kyoung, Joo-Hyun;Kim, Sean-Mi;Hu, Jong-Wan
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.42 no.6
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    • pp.787-792
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    • 2022
  • In winter, the excessive use of deicing salt deteriorates concrete pavement durability. To reduce the amount of deicing salt used, phase-change materials (PCMs) potentially offer an alternative way to melt snow through their latent heat storage characteristics. In this research, thermal energy storage concrete was developed by using PCM-impregnated expanded clay as 50 % replacement to normal aggregate by volume. In addition, to improve the thermal efficiency of PCM lightweight aggregate (PCM-LWA)-incorporated concrete, multi-walled carbon nanotubes (MWCNTs) were incorporated in proportions of 0.10 %, 0.15 %, and 0.20 % by binder weight. Compressive strength testing and programmed thermal cycling were performed to evaluate the mechanical and thermal responses of the PCM-LWA concrete. Results showed a significant strength reduction of 54 % due to the PCM-LWA; however, the thermal performance of the PCM-LWA concrete was greatly improved with the addition of MWCNTs. Thermal test results showed that 0.10 % MWCNT-incorporated concrete had high thermal fatigue resistance as well as uniform heat flow, whereas specimens with 0.15 % and 0.20 % MWCNT content had a reduced thermal response due to supercooling when the ambient temperature was varied between -5℃ and 10℃.

Protective Effect of Tongyuhwalhyeol-tang on Liver Injury in Thioacetamide-induced Rat (Thioacetamide 유발 간손상모델에서 통규활혈탕의 간보호효과)

  • Kim, Kyeong Jo;Shin, Mi-Rae;Kim, Soo Hyun;Kim, Su Ji;Lee, Ah Reum;Kwon, Ojun;Roh, Seong-Soo
    • The Korea Journal of Herbology
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    • v.33 no.1
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    • pp.37-46
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    • 2018
  • Objectives : Liver disease is an inflammatory reaction caused by oxidative stress, viral, alcohol, and drug properties. Inflammatory reaction causes hepatitis and chronic hepatitis is persistent, it progresses to liver fibrogenesis and liver cancer. The aim of this study was to confirm the hepatoprotective effect of Tongyuhwalhyeol-tang(Tongqiaohuoxue Decoction) (TH) and Gamtongyuhawlhyeol-tang(GTH) in TAA-induced liver injury animal model. Methods : The antioxidant activities were evaluated through in vitro experiments, such as 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and 2, 2'-azinobis-3-ethyl-benzothiazoline-6-sulfonic acid (ABTS) radical scavenging assays, total polyphenol and total flavonoid content measurement. To confirm the liver protective effect, induced by Thioacetamide (TAA) for 3 days injection at 200 mg/kg rats. TH and GTH were treated 3 days at 200 mg/kg/day. The changes of reactive oxygen species (ROS), peroxynitrite ($ONOO^-$), alanine aminotransferanse (ALT) and aspartate aminotransferase (AST) in serum were analyzed after experiment. Also, expression of anti-inflammation, anti-oxidant related proteins were investigated by western blot analysis. Results : TH was inhibited the antioxidant activities. In the TAA-induced rat, TH decreased ROS, $ONOO^-$, ALT, AST level in serum. Inflammation related protein expressions increased in TAA-induced rat compared to normal rat. However, TH group inhibited the down expression of these proteins. Also, anti-oxidant related protein expressions increased in TH group compared TAA-induced rat. Conclusion : Therefor, these results suggested that TH provided hepatoprotective effects on the hepatic injury leading to the reduction of inflammatory response. In addition, the effect of TH was superior to that of GTH.

Muscle oxygenation, endocrine and metabolic regulation during low-intensity endurance exercise with blood flow restriction

  • Hwang, Hyejung;Mizuno, Sahiro;Kasai, Nobukazu;Kojima, Chihiro;Sumi, Daichi;Hayashi, Nanako;Goto, Kazushige
    • Korean Journal of Exercise Nutrition
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    • v.24 no.2
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    • pp.30-37
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    • 2020
  • [Purpose] The present study investigated the effect of endurance exercise with blood flow restriction (BFR) performed at either 25% maximal oxygen uptake (${\dot{V}}O_2$ max) or 40% ${\dot{V}}O_2$ max) on muscle oxygenation, energy metabolism, and endocrine responses. [Methods] Ten males were recruited in the present study. The subjects performed three trials: (1) endurance exercise at 40% ${\dot{V}}O_2$ max without BFR (NBFR40), (2) endurance exercise at 25% ${\dot{V}}O_2$ max with BFR (BFR25), and (3) endurance exercise at 40% ${\dot{V}}O_2$ max with BFR (BFR40). The exercises were performed for 15 min during which the pedaling frequency was set at 70 rpm. In BFR25 and BFR40, 2 min of pressure phase (equivalent to 160 mmHg) followed by 1 min of release phase were repeated five times (5 × 3 min) throughout 15 minutes of exercise. During exercise, muscle oxygenation and concentration of respiratory gases were measured. The blood samples were collected before exercise, immediately after 15 min of exercise, and at 15, 30, and 60 minutes after completion of exercise. [Results] Deoxygenated hemoglobin (deoxy-Hb) level during exercise was significantly higher with BFR25 and BFR40 than that with NBFR40. BFR40 showed significantly higher total-hemoglobin (total-Hb) than NBFR40 during 2 min of pressure phase. Moreover, exercise-induced lactate elevation and pH reduction were significantly augmented in BFR40, with concomitant increase in serum cortisol concentration after exercise. Carbohydrate (CHO) oxidation was significantly higher with BFR40 than that with NBFR40 and BFR25, whereas fat oxidation was lower with BFR40. [Conclusion] Deoxy-Hb and total Hb levels were significantly increased during 15 min of pedaling exercise in BFR25 and BFR40, indicating augmented local hypoxia and blood volume (blood perfusion) in the muscle. Moreover, low-and moderate-intensity exercise with BFR facilitated CHO oxidation.

A Study on the Effectiveness of the Hazardous Chemical Transport Vehicle Management System (유해화학물질 운반차량 관리제도 실효성 연구)

  • Kim, Sungbum;Lee, HyunSeung;Jeong, Seongkyeong
    • Journal of the Society of Disaster Information
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    • v.17 no.4
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    • pp.794-801
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    • 2021
  • Purpose: The effectiveness of the transport vehicle management system of the Chemical Substances Control Act will be studies and used as basic data for future system improvement plans. Method: After the enforcement of the Chemical Substances Control Act, the effectiveness for the transport vehicle management system was studies by comparing the transport plan, guidance and inspection status, safety training completion management, ect., and the reduction rate of chemical accidents. Results: The average number of chemical accidents in transport vehicles nationwide is 20 each year. And It is decreasing with the stabilization of the Chemical Substances Control Act('15.1.1). The first reason for the decrease in chemical accidents is the increase in submission of transport plans. Second, as the guidance and inspection rate increased every year, the shipper company's management of transport companies was naturally strengthened. Finally, it is judged that chemical accident caused by transport vehicles decrease through safety education. Conclusion: The current tranport vehicle management system of the Chemical Substances Control Act is effective. However, further research is needed to improve the practical and efficient transport vehicle management system.

Study on the Shape of Appendage for the Reduction of Motion of Floating Wind Turbine Platforms (부유식 풍력 하부구조물의 운동 저감을 위한 부가물 형상 연구)

  • Dae-Won Seo;Jaehyeon Ahn;Jungkeun Oh
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.28 no.7
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    • pp.1201-1208
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    • 2022
  • In general, to maximize the supply and efficiency of floating offshore wind power generation energy, the motion caused by wave attenuation of the substructure must be reduced. According to previous studies, the motion response was reduced due to the vortex viscosity generated by the damping plate installed in the lower structure among the waves. In this study, a 5 MW semi-submersible OC5 platform and two platforms with attenuation plates were designed, and free decay experiments and numerical calculations were performed to confirm the effect of reducing motion due to vortex viscosity. As a result of the model test, when the heave free decay tests were conducted at drop heights of 30 mm, 40 mm, and 50 mm, compared with the OC5 platform, the platform with two types of damping plates attached had relatively improved motion damping performance. In the model test and numerical calculation results, the damping plate models, KSNU Plate 1 and KSNU Plate 2, were 1.1 times and 1.3 times lower than OC5, respectively, and the KSNU Plate 2 platform showed about two times better damping performance than OC5. This study shows that the area of the damping plate and the vortex viscosity are closely related to the damping rate of the heave motion.

A Study on Calculation of Appropriate Size of Public Officials Using DEA (DEA를 활용한 공무원의 적정규모 산정에 관한 연구)

  • Kwon, Sun-Phil;Mun, Tae-Hyoung
    • Journal of Industrial Convergence
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    • v.20 no.11
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    • pp.135-140
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    • 2022
  • A study to estimate the appropriate size for the quota of civil servants during the period of change of government is required. Therefore, in this study, we would like to introduce a study that uses DEA to estimate the appropriate size of public officials. The department of a public institution is DMU, and the number of employees in each department is applied as an input variable, and the number of electronic approval production documents and the number of electronic approval expenditures are applied as output variables. MaxDEA 8 was used as an analysis program for this purpose. As a result of the analysis, when the efficiency level was 1.00 (100%), 3 out of 14 departments showed the optimal level by satisfying the efficiency, and 10 of the remaining departments scored 0.50 (50%) with a score of 0.50 (50%), confirmed to be relatively inefficient. In other words, it was confirmed that most departments had inefficient surplus staff. As an additional analysis, we calculated the number of possible staff reductions using the efficiency level. Using this, it is expected that the field of manpower reduction can be discovered in advance through an analysis of manpower efficiency by department, and based on this, it can be used to relocate manpower by department according to future response strategies.