• Journal of Applied Biological Chemistry
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• 제49권2호
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• pp.51-56
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• 2006

Metanolic root extract of Glycine max (L.) Merr. was chromatographed, affording three triterpenoids 1-3. The compound 3 was isolated from microorganism called Fusarium sporotrichioides but never been isolated from any plant sources. Compounds 1-3 showed cytotoxic activity against HT-59 human cancer cell line with $IC_{50}$ values of 62.9, 20.0, and $44.2{\mu}M$, respectively. Compound 3 showed significant activities against Gram-positive bacterial such as Bacillus cereus, Bacillus subtilis, and Staphylococcs aureus.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1998년도 Advances in Ginseng Research - Proceedings of the 7th International Symposium on Ginseng -
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• pp.138-145
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• 1998

A validated and reproducible HPLC method was developed for the profiling and quantitative analysis of ginsenosides in commercial products available in North America. Analysis of 280 Panax ginseng and Panax quinquefolius products showed profiles indicative of the presence of ginsenosides in the majority of these products. However, the quantitative contents of the products vary greatly, not only in products of different formulations, but also of products within each of the fromulations examined.

• 전기학회논문지
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• 제62권6호
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• pp.881-885
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• 2013

In this paper, we present a deterioration judgment model of urban rail power equipment using driving history, the frequency and number of failures. In addition, we have developed a deterioration judgment program based on the derived failure rate. A deterioration judgment model of power equipments on metro system was designed to establish how much environmental factors, such as thermal cycling, humidity, overvoltage and partial discharge. The deterioration rate of the transformers followed the Arrhenius log life versus reciprocal Kelvin temperature (hotspot temperature) relation. The deterioration judgment program is linked to the online condition monitoring system of urban railway system. The deterioration judgment program is based on the user interface it is possible to apply immediately to the urban rail power equipment.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 제36회 하계학술대회 논문집 전기설비
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• pp.100-102
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• 2005

This paper is purpose to introduce the database management program of insulation tests for high voltage rotating machines. KEPRI has carried out insulation tests for high voltage equipment since 1998, the number of tests grow larger every year. It is difficult to manage the numerous test results, so we developed the insulation diagnostic database program. The features of this program are an easy-search test result and making a graph of AC, tan${\Delta}$ test. the most useful function is the trend management. Using the trend function, we can find the aging deterioration for high voltage machines easily.

• Journal of Positioning, Navigation, and Timing
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• 제10권2호
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• pp.139-144
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• 2021

In this paper, we described configuration and construction of infrastructure for the KASS Reference Station (KRS), subsystem of Korea Augmentation Satellite System (KASS). KASS system consists of three subsystems(KRS, Mission Control Center (MCC), KASS Uplink Station (KUS)). One of these subsystems, KRS receives GNSS data for generating range error and integrity verification and sends to MCC. It is needed to antenna facilities for mounting GNSS antenna and shelter for operating KRS and infra equipment(power and network system, lightning and grounding system, fire extinguish) for operating KRS. For this reason, we have established the requirements for KRS infrastructure and constructed infrastructure for KRS to meet the requirements of KRS infrastructure.

• International Journal of Human Ecology
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• 제11권1호
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• pp.65-74
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• 2010

Family professionals and family program staff need to consider the importance of program evaluation in Korea since an increasing number of Healthy Family Support Centers are providing diverse intervention and education programs. The purpose of this research paper is to (a) introduce a program evaluation model that includes the program life cycle; (b) help family professionals and family program staff understand the link between program implementation and evaluation processes; and (c) facilitate discussions in terms of program evaluation of Healthy Family Support Centers and evaluation roles of different levels of Healthy Family Support Centers including the headquarters, regional, and local centers. Understanding the program life cycle and relevant evaluation processes will help family professionals and family program staff be more strategic in answering critical questions about a program's effectiveness. The benefits of program evaluation and its implications are discussed.

• Molecules and Cells
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• 제27권5호
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• pp.563-570
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• 2009

We previously isolated the OsCBT gene, which encodes a calmodulin (CaM)-binding protein, from a rice expression library constructed from fungal elicitor-treated rice suspension cells. In order to understand the function of OsCBT in rice, we isolated and characterized a T-DNA insertion mutant allele named oscbt-1. The oscbt-1 mutant exhibits reduced levels of OsCBT transcripts and no significant morphological changes compared to wild-type plant although the growth of the mutant is stunted. However, oscbt-1 mutants showed significant resistance to two major rice pathogens. The growth of the rice blast fungus Magnaporthe grisea, as well as the bacterial pathogen Xanthomonas oryzae pv. oryzae was significantly suppressed in oscbt-1 plants. Histochemical analysis indicated that the hypersensitive-response was induced in the oscbt-1 mutant in response to compatible strains of fungal pathogens. OsCBT expression was induced upon challenge with fungal elicitor. We also observed significant increase in the level of pathogenesis-related genes in the oscbt-1 mutant even under pathogen-free condition. Taken together, the results support an idea that OsCBT might act as a negative regulator on plant defense.

• Bulletin of the Korean Chemical Society
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• 제31권1호
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• pp.52-58
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• 2010

Human histamine H1 receptor (HHR1) is a G protein-coupled receptor and a primary target for antiallergic therapy. Here, the ligand-based three-dimensional pharmacophore models were built from a set of known HHR1 inverse agonists using HypoGen module of CATALYST software. All ten generated pharmacophore models consist of five essential features: hydrogen bond acceptor, ring aromatic, positive ionizable and two hydrophobic functions. Best model had a correlation coefficient of 0.854 for training set compounds and it was validated with an external test set with a high correlation value of 0.925. Using this model Maybridge database containing 60,000 compounds was screened for potential leads. A rigorous screening for drug-like compounds unveiled RH01692 and SPB00834, two novel molecules for HHR1 with good CATALYST fit and estimated activity values. The new lead molecules were docked into the active site of constructed HHR1 homology model based on recently crystallized squid rhodopsin as template. Both the hit compounds were found to have critical interactions with Glu177, Phe432 and other important amino acids. The interpretations of this study may effectively be deployed in designing of novel HHR1 inverse agonists.

• 한국임상수의학회지
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• 제31권5호
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• pp.421-424
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• 2014

세 마리의 소형견이 4단계의 내측 슬개골 탈구로 내원하였다. 세 마리 모두에서 일반적인 기존 수술 방법으로는 슬개골 탈구가 환납되지 않았다. 따라서 슬개골 탈구를 교정하기 위해 대퇴 단축 절골술이 실시되었다. 수술 후에 세 마리 모두 임상 증상이 개선되었고 합병증이나 재발은 확인되지 않았다. 대퇴 단축 절골술은 심한 골격 기형과 관련된 내측 슬개골 탈구가 있는 소형견에서 효과적인 치료 방법으로 고려될 수 있다.

• 수산해양교육연구
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• 제22권3호
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• pp.431-444
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• 2010

This research aims at developing a teachers' training program to reinforce teachers' capability to perform the action learning program. To accomplish this goal, the key value of the training program based on action learning, the process of the core learning activities, and the elements to support learners and facilitators respectively were deducted on the foundation of documentary research and case study, based on which, the program was developed through the formative test by professionals and application to the field. This research was applied to 105 middle or high school teachers, the participants of the in-service training on creative problem solving hosted by B metropolitan city for one week (30 hours) from 9 a.m. on Monday, January 25th, 2010 to 4 p.m. on Friday, January 29th. The result of this research is as follows. First, as for the key values of this study, (1) the team-based learning centered on the trainees, not lecturers-oriented, knowledge-transmitting training, is possible, (2)for each process, guidelines, related information, tools, and various kinds of media are supported just in time, and (3)a focus is given on fostering facilitators centered on teachers. Second, the process of the core learning activities of the teachers' training program based on action learning consists of the procedure of a prior lecture${\rightarrow}$break${\rightarrow}$investigation into problems${\rightarrow}$clarification of problems${\rightarrow}$drawing possible solutions${\rightarrow}$decision on the priority${\rightarrow}$making an action plan${\rightarrow}$performance${\rightarrow}$evaluation, and on each stage, the contents for the activities of teachers and learners and detailed supportive elements are offered.