• Title/Summary/Keyword: Reports

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Investigating the Status of WHO VigiAccess Adverse Drug Event Reporting and Exploring its Potential for Application Using Anti-Obesity Agents as Examples (VigiAccess를 통한 WHO의 약물 이상사례 보고 현황 검색과 그 활용 가능성 탐색 : 비만 치료제를 중심으로)

  • Mikyung Kim
    • The Journal of Internal Korean Medicine
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    • v.45 no.1
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    • pp.55-74
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    • 2024
  • Objectives: This study reviewed the status of adverse event (AE) reporting in VigiAccess using anti-obesity agents as examples and explored the possibility of its use and future challenges. Methods: AE reports related to some representative drugs among herbal medicines (HMs), complex HM prescriptions, ingredients of supplements, and over-the-counter and prescription medicines were investigated using VigiAccess on February 1, 2024. Results: AE reports on prescription drugs were overwhelmingly higher than those on HMs or supplements. Although most reports were submitted from North America, reports on Ephedra sinica and green tea extract (GTE) were more from Asia and Europe, respectively. The female population reported more, and the difference in the sex ratio was the smallest for Ephedra spp. The age group was concentrated on young adults, but many older patients reported GLP-1 receptor agonist-related AEs. Symptoms related to the gastrointestinal and nervous systems were most commonly reported, but mental and cardiac disorders were common in Ephedra-type HMs. Hepatobiliary disorders are also commonly found in GTE-related reports. Conclusions: VigiAccess was useful for easily checking the global status of AE reporting for prescription drugs. However, several limitations were observed in using VigiAccess for HMs because of the few reports. Thus, it is necessary to increase the number of reports by education and to promote AE reporting among HM prescribers and users. The full range of HMs should be included in the pharmacovigilance system, and the coding and classification of HMs should be revised.

A Study on the Records Management for Evidence-Based Accountability of Corporations : Focusing on Sustainability Reports (기업의 증거기반 설명책임을 위한 기록관리 방안 '지속가능성보고서'를 중심으로)

  • Jung, Mi Ri;Yim, Jin-Hee
    • The Korean Journal of Archival Studies
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    • no.48
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    • pp.45-92
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    • 2016
  • Corporations report their economical, environmental, social influences and achievements through sustainability reports. Apart from the financial reports, which are subject to legal restrictions, sustainability reports inform non financial achievements of a corporation, thus the reliability of the information is solely dependent on the corporation itself. The current sustainability reports are of types that cannot include proof or source of the index data, thus they are tended to be regarded as means of publicity. The reliability of the reports is often questioned. This research applied the concept of Evidence-Based Accountability, which will allow the confirmation of accountability through records including contents and context of the tasks. Evidence-Based Accountability means producing and accumulating witness records of actions, then managing the records as usable information and use them as accountability information. Index data from sustainability reports of domestic corporations and web based reports of Vodafone was reviewed. Measures to link task records as proof of index data was studied. To make this possible, record production and acquisition system was redesigned in order to secure required records as evidence. Linked build-up of SR system and RMS was proposed. The proposed system will allow collection and management of records as SR accountability information, and provide the data when necessary. Also, corporate infrastructure was proposed. This infrastructure will build a professional records management system in stages, through organizational system and regulations. Cooperation of staff in this infrastructure will support reliable corporate accountability.

Dynamic Threshold Determination Method for Energy Efficient SEF using Fuzzy Logic in Wireless Sensor Networks (무선 센서 네트워크에서 통계적 여과 기법의 에너지 효율 향상을 위한 퍼지논리를 적용한 동적 경계값 결정 기법)

  • Choi, Hyeon-Myeong;Lee, Sun-Ho;Cho, Tae-Ho
    • Journal of the Korea Society for Simulation
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    • v.19 no.1
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    • pp.53-61
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    • 2010
  • In wireless sensor networks(WSNs) individual sensor nodes are subject to security compromises. An adversary can physically capture sensor nodes and obtain the security information. And the adversary injects false reports into the network using compromised nodes. If undetected, these false reports are forwarded to the base station. False reports injection attacks can not only result in false alarms but also depletion of the limited amount of energy in battery powered sensor nodes. To combat these false reports injection attacks, several filtering schemes have been proposed. The statistical en-routing filtering(SEF) scheme can detect and drop false reports during the forwarding process. In SEF, The number of the message authentication codes(threshold) is important for detecting false reports and saving energy. In this paper, we propose a dynamic threshold determination method for energy efficient SEF using fuzzy-logic in wireless sensor networks. The proposed method consider false reports rate and the number of compromised partitions. If low rate of false reports in the networks, the threshold should low. If high rate of false reports in networks, the threshold should high. We evaluated the proposed method’s performance via simulation.