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Analysis of Characteristics and Prognostic Factors in Adult Patients Receiving Mechanical Ventilation in the Medical Intensive Care Unit of a University Hospital (한 대학병원 내과계 중환자실의 기계환기 시행 환자의 현황 및 예후인자의 분석)

  • Song, Jin Woo;Choi, Chang-Min;Hong, Sang-Bum;Oh, Yeon-Mok;Shim, Tae Sun;Lim, Chae-Man;Lee, Sang-Do;Kim, Woo Sung;Kim, Dong Soon;Kim, Won Dong;Koh, Younsuck
    • Tuberculosis and Respiratory Diseases
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    • v.65 no.4
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    • pp.292-300
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    • 2008
  • Background: Respiratory failure is a common condition that requires intensive care, and has a high mortality rate despite the recent improvements in respiratory care. Previous reports of patients with respiratory failure focused on the specific disease or included a large proportion of surgical patients. This study evaluated the clinical characteristics, outcomes and prognostic factors of adult patients receiving mechanical ventilation in a medical intensive care unit. Methods: Retrospective chart review was performed on 479 adult patients, who received mechanical ventilation for more than 48 hours in the medical ICU of one tertiary referral hospital. Results: The mean age of the patients was $60.3{\pm}15.6$ years and 34.0% were female. The initial mean APACHE III score was $72.3{\pm}25$. The cause of MV included acute respiratory failure (71.8%), acute exacerbation of chronic pulmonary disease (20.9%), coma (5.6%), and neuromuscular disorders (1.7%). Pressure controlled ventilation was used as the initial ventilator mode in 67.8% of patients, and pressure support ventilation was used as the initial weaning mode in 83.6% of the patients. The overall mortality rate in the ICU and hospital was 49.3% and 55.4%, respectively. The main cause of death in hospital was septic shock (32.5%), respiratory failure (11.7%), and multiorgan failure (10.2%). Males, an APACHE III score >70, the cause of respiratory failure (interstitial lung disease, coma, aspiration, pneumonia, sepsis and hemoptysis), the total ventilation time, and length of stay in hospital were independently associated with mortality. Conclusion: The cause of respiratory failure, severity of the patients, and gender appears to be significantly associated with the outcome of mechanical ventilatory support in patients with respiratory failure.

The Economic Growth of Korea Since 1990 : Contributing Factors from Demand and Supply Sides (1990년대 이후 한국경제의 성장: 수요 및 공급 측 요인의 문제)

  • Hur, Seok-Kyun
    • KDI Journal of Economic Policy
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    • v.31 no.1
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    • pp.169-206
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    • 2009
  • This study stems from a question, "How should we understand the pattern of the Korean economy after the 1990s?" Among various analytic methods applicable, this study chooses a Structural Vector Autoregression (SVAR) with long-run restrictions, identifies diverse impacts that gave rise to the current status of the Korean economy, and differentiates relative contributions of those impacts. To that end, SVAR is applied to four economic models; Blanchard and Quah (1989)'s 2-variable model, its 3-variable extensions, and the two other New Keynesian type linear models modified from Stock and Watson (2002). Especially, the latter two models are devised to reflect the recent transitions in the determination of foreign exchange rate (from a fixed rate regime to a flexible rate one) as well as the monetary policy rule (from aggregate targeting to inflation targeting). When organizing the assumed results in the form of impulse response and forecasting error variance decomposition, two common denominators are found as follows. First, changes in the rate of economic growth are mainly attributable to the impact on productivity, and such trend has grown strong since the 2000s, which indicates that Korea's economic growth since the 2000s has been closely associated with its potential growth rate. Second, the magnitude or consistency of impact responses tends to have subsided since the 2000s. Given Korea's high dependence on trade, it is possible that low interest rates, low inflation, steady growth, and the economic emergence of China as a world player have helped secure capital and demand for export and import, which therefore might reduced the impact of each sector on overall economic status. Despite the fact that a diverse mixture of models and impacts has been used for analysis, always two common findings are observed in the result. Therefore, it can be concluded that the decreased rate of economic growth of Korea since 2000 appears to be on the same track as the decrease in Korea's potential growth rate. The contents of this paper are constructed as follows: The second section observes the recent trend of the economic development of Korea and related Korean articles, which might help in clearly defining the scope and analytic methodology of this study. The third section provides an analysis model to be used in this study, which is Structural VAR as mentioned above. Variables used, estimation equations, and identification conditions of impacts are explained. The fourth section reports estimation results derived by the previously introduced model, and the fifth section concludes.

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Analysis of the "Korean Wave" News Frame of Chinese Daily Newspapers: Based on the Analysis of Articles Reported between 2001 and 2010 (중국 일간지의 "한류" 보도에 나타난 프레임 분석: 2001~2010년 기간에 보도된 기사 분석을 중심으로)

  • Yu, Sae-Kyung;Lee, Suk;Chung, Ji-In
    • Korean journal of communication and information
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    • v.57
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    • pp.202-226
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    • 2012
  • The purpose of this study is to analyze how Chinese people perceive the acceptance and spread of Korean popular culture through the analysis of the Korean Wave news frame in Chinese daily newspapers. The result of analysis showed that there was a significant difference in the number of an article appearance in all three daily newspapers by year according to a specific issue including the popularity of Korean Wave-related events, Korean dramas, movies and Korean stars. This reporting trend also appeared in the article format, and all three daily newspapers mainly used an episodic frame to deliver fragmentary Korean Wave trend or personal information emotionally rather than a thematic frame to analyze and interpret the Korean Wave trend in depth. As a result of analyzing dominant news frames using the inductive approach to examine specific contents of the articles, news frames that composed the Korean Wave into the cultural interest frame as 'Interest and attention toward Korean popular culture' and gave positive evaluations were dominant, followed by the economic news frames that explained the Korean Wave from the economic perspective and the political news frames that considered the Korean Wave from the viewpoint of the Chinese Government. These news frames appeared somewhat different according to the publishing purpose of daily newspapers. ${\ll}$People's Daily${\gg}$ which is the official organ of the Chinese Communist Party often covered the political frames to report the policies of Chinese government, ${\ll}$People's Daily (Overseas edition)${\gg}$ often covered economic frames from the overseas perspective and the Jinghua Daily which is a commercial newspaper by nature often handled cultural interest frames to consider Korean Wave as new cultural phenomenon.

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Study on the Rice Yield Reduction and Over head Flooding Depth for Design of Drainage System (배수 설계를 위한 벼의 관수심 및 관수피해율에 관한 연구)

  • 김천환;김시원
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.24 no.4
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    • pp.69-79
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    • 1982
  • The objective of this study is to contribute to drainage planning in the most realistic and economical way by establishing the relationship between rice yield reduction and overhead flooding by muddy water of each growth stage of paddy, which is the most important factor in determining optimum drainage facilities. This study was based on the data mainly from the experimental reports of the Office of Rural Development of Korea, Reduction Rate Estimation for Summer Crops, published by Ministry of Agriculture and Forestry of Japan and other related research documenta- tion. The results of this study are summarized as follows 1. Damages by overhead flooding are highest in heading stage and have the tendency of decrease in the order of booting stage, panicle formation stage, tillering stage, and stage just after transplanting. Damages by overhead flooding of each growing stage are as follows: a) It is considered that overhead flooding just after transplanting gives a little influence on plant growth and yield because the paddy has sufficient growth period from floo ding to harvest time. b) Jt is analyzed that according to the equation y=11 12x 0.908 which is derived from this study, damages by overhead flooding during tillering stage for 1, 2, 3 successive days are 11.1 %, 20.9%, and 30.2% respectively. c) Damages by overhead flooding after panicle formation stage are very serious because recovering period is very short after damage and ineffective tillering is much. Acc- ording to the equation y=9. 58x+10. Ol derived from this study, damages by overhead flooding fal 1,2,3,5 successive days are 19.6%, 29.2%, 38.8%, 57.9% respectively. d) Booting stage is the very important period in which young panicle has grown up almost completely and the number of glumous flower is fixed since reduction division takes place in the microspore mother cell and enbryo mother cell. According to the equation y=39. 66x 0.558 derived from this study, damages by overhead floodingfor 0.5, 1, 3, 5 successive days are 26.9%, 39.7%, 72. 2% and 97.4%, respectively. Therefore, damages by overhead flooding is very serious during the hooting stage. e) When ear of paddy emerges, flowering begins on that day or the next day; when paddy flowers, fertilization will be completed 2-3 hours after flowering. Therefore overhead flooding during heading stage impedes flowering and increases sterilizing percentage. From this reason damages of heading stage are larger than that of booting stage. According to the equation y-41 94x 0.589 derived from this study, damages by overhead flooding for 0.5, 1, 3, 5, successive days are 27.9%, 63.1 %, 80.1%, and 100% 2. Considering that temperature of booting stage is higher than that of beading stage and plant height of booting stage is ten centimeters shorter than that of heading stage, booting stage should be taken as a critical period for drainage planning because possi- bility of damage occurrence in booting stage is larger than that of heading stage. There-fore, it is considered that booting stage should be taken as critical period of paddy growth for drainage planning. 3. Overhead flooding depth is different depending on the stage of growth. In case, booting stage is adopted as design stage of growth for drainage planning, it is conside red that the allowable flooding depth for new varieties and general varieties are 70cm and 80cm respectively. 4. Reduction Rate Estimation by Wind and Flood for Rice Planting of the present design criteria for drainage planning shows damage by overhead flooding for 1 to 2, 3 to 4, 5 to 7 consecutive days; damages by overhead flooding varies considerably over several hours and experimental condition of soil, variety of paddy, and climate differs with real situation. From these reasons, damage by flooding could not be estimated properly in the past. This study has derived the equation which shows damages by flooding of each growth stage on an hourly basis. Therefore, it has become possible to compute the exact damages in case duration of overhead flooding is known.

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A Study on Fishing Efficiency and By-Catch of Small Fish of Winged Stow Net Fishery (연안 낭장망어업의 어획성능과 소형어 혼획에 관한 연구)

  • Kim, Joo-Seong;Lee, Ju-Hee
    • Journal of Fisheries and Marine Sciences Education
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    • v.8 no.1
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    • pp.92-107
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    • 1996
  • Based on the act.ivity report for the coastal fisheries resources conducted from 1982 to 1989 by West, East Research Institute of Fisheries, some other reports from Korea Rural Economics Institute and etc., and the questionnaire results for the senses of fishermen, the fishing efficiency and conditions of by - catch of small fish in winged stow net were analized, and then some ways to prevent from by - catch of small fishes were suggested in this paper. The nationwide conditions of Permission and Disposal in winged stow net fishery arc that number of cases of coastal winged stow net fishery has dropped to 757 by 1994 while it was 961 in 1991 and that the number of cases of a sectional winged stow net fishery on the contrary has increased to 302 by 1994 while it was 11 in 1991. Regardless of region, catch per net by year in general has been on gradual increase in 1982 through 1989, but that showed decrease in 1994. From the view of region, the proportion of by - catch of shrimps and blenny is higher in Kyonggi, Chungnam with West Sea and that of anchovy and blenny is higher in Chonbuk, Chonnam, Kyongnam with South Sea. The average proportions of by - catch of small fish for 5 years from 1985 to 1989 are 86.9% for sand lance, 69% for anchovy, 63% for big eyed herring, 51% for blenny, 22% for Southern rough shrimp and 19% for akiami paste shrimp, hence sand lance and anchovy are highly by - catch effective while shrimps is not. Ways to prevent the over fishing of small fish in winged stow net fishery includes reduction of fishing frequency during April and August through November, the very season for small fish, use of meshes large enough for small fish to go through and assignment of fishing area to other than habitats of stationary fish.

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A Study on the Effectiveness and Possibility of General Chemistry Experiment Lecture with Flipped Classroom (거꾸로 교실을 적용한 일반화학실험 강좌의 효과 및 가능성 탐색 연구)

  • Yoon, Jihyun;Son, E Nok;Kang, Seong-Joo
    • Journal of the Korean Chemical Society
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    • v.62 no.2
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    • pp.124-136
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    • 2018
  • In this study, we applied the flipped-classroom to the general chemistry experiment lecture of the domestic university with strong teacher-led, and explored the effects and possibilities of the course. For this purpose, 30 students who were enrolled in the Science Education Department of the College of Education in the metropolitan area were randomly assigned to two groups, namely, the flipped-classroom group and the traditional class group. Then, we developed a general chemistry experiment lessons based on the flipped-classroom along with visual materials and we applied the lessons for 15 weeks. After all the classes, we conducted a survey to see the students' perception of the general chemistry experiment lecture by flipped classroom. As a result of analysis, the students of the flipped-classroom group were more positive than the students of the traditional class group in terms of the usefulness of the class activity, the importance of each activity element for the successful learning, the learning level, and the intention for another lesson. As a result of analyzing students' perceptions in terms of general chemical experiment activities such as conducting experiments or writing reports and understanding the contents of experiments, the average score of the flippedclassroom group was higher than the traditional class group, and the main cause of this result was the video material provided by prior learning activities. In addition, as a result of analyzing students' perceptions in terms of interactions and self-directed learning in class, the average score of the flipped-classroom group was generally higher than the traditional class group. In particular, students' interactions and self-directed learning were statistically significant differences between the two groups. And the students' perception of video material was very positive, and it was analyzed that the video that the instructor directly explained experiment theory and method was the most favorite videos of students. We discussed educational implications of these findings.

The Long-term Clinical Result of St. Jude Mechanical Valve Replacement (St. Jude 기계판막 치환술의 장기 임상성적)

  • 배윤숙;정성철;김우식;정승혁;유환국;이정호;김병열
    • Journal of Chest Surgery
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    • v.36 no.5
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    • pp.321-328
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    • 2003
  • Background: The St. Jude Medical prosthesis is one of the popularly used artificial prosthesis, therefore the National Medical Center reports the long-term clinical results of patients who underwent prosthetic valve replacement with St. Jude medical valve for 18 years. Material and Method: Between January, 1984 and June, 2002, a series of 163 consecutive patients who had Implanted St. Jude prosthesis at the National Medical Center were reviewed. Mean age was 42.9$\pm$15.1 years and male to female ratio was 69:94. The operative procedure comprised of 87 MVR, 30 AVR, 45 DVR, and 1 TVR. The reoperative procedure comprised of 21 MVR, 2 AVR, and 14 DVR. Follow-up rate was 96.9%, and cumulative follow-up was 823.8 patient-years. Result: Early mortality rate was 7.9% (13 patients), late mortality rate was 8.7% (13 patients) and late mortality due to valve related complication was 47% (7 patients). Actual survival rate at 10 and 18 years were 91.7$\pm$2.1% and 91.0$\pm$1.9%. Linearized Incidence was as follows: thromboembolism, 1.09%/ patient-year; anticoagulant related hemorrhage, 0.36%/patient-year; valve thrombosis, 0.24%/patient-year; paravalvular leakage, 0.12%/patient-year; and prosthetic bacterial endocarditis, 0.12%/patient-year linearized incidence of over all valve related complication was 1.94%/patient-year. Freedom from valve related complication at 10 and 18 years were 89.1$\pm$3.3% and 88.4$\pm$3.9%. Freedom from valve related death at 10 and 18 years were 95.1$\pm$1.2% and 95.1$\pm$1.0%. Valve related complication was related the age of patient, especially anticoagulant related hemorrhage was more common in patients over 60 years of age. Valve related complication, death were higher in DVR than AVR or MVR, and valve related death was higher in reoperation. There was no relationship between valve related complication or death and implant valve of size. Conclusion: The long-term clinical results of patients implanted with St. Jude Mechanical prosthesis was quite satisfactory with a low incidence of valve related complication and mortality.

Preoperative Concurrent Radiochemotherapy for Locally Advanced Esophageal Cancer: Treatment Outcome and Prognostic Factors (국소 진행된 식도암에 대한 수술 전 동시병용 방사선-항암 화학요법: 치료 성적과 예후인자에 대한 연구)

  • Kim, Hae-Young;Kim, Kwan-Min;Kim, Jhin-Gook;Shim, Young-Mog;Im, Young-Hyuck;Ahn, Yong-Chan
    • Radiation Oncology Journal
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    • v.25 no.3
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    • pp.160-169
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    • 2007
  • Purpose: This study reports the results of the use of preoperative concurrent radiochemotherapy (CRCT) for the treatment of locoregionally advanced esophageal cancer. Materials and Methods: From 1998 through 2005, 61 patients with intrathoracic esophageal cancer at stages II-IVB (without distant organ metastasis and presumed to be respectable) received preoperative CRCT. CRCT consisted of radiotherapy (45 Gy /25 fractions /5 weeks) and FP chemotherapy (5-FU 1 g/$m^{2}$/day, days 1-4 and 29-32, Cisplatin 60 mg/$m^{2}$/day, days 1 and 29). An esophagectomy was planned in $4{\sim}6$ weeks after the completion of CRCT. Results: There were two treatment-related deaths. Among the 61 patients, 53 patients underwent surgery and 17 patients achieved a pathological complete response (pCR). The overall survival (OS) rates of all 61 patients at 2 and 5 years were 59.0% and 38.0%, respectively. The rates of OS and disease-free survival (DFS) of the surgically resected patients at 2 and 5 years were 61.6%, 40.1 % and 53.3%, 41.8%, respectively. By univariate analysis, achieviement of pCR and a clinically uninvolved distant lymph node (cMO) were favorable prognostic factors for OS and DFS. There were 27 patients that experienced a relapse-a locoregional relapse occurred in 5 patients, a distant metastasis occurred in 12 patients and combined failure occurred in 10 patients. Conclusion: The results of the current study are favorable. pCR and an uninvolved distant lymph node were found to be favorable prognostic factors.

Statistical Errors in Papers Published in the Journal of the Korean Society for Therapeutic Radiology and Oncology (대한방사선종양학회지 게재 논문의 통계적 오류 현황)

  • Park, Hee-Chul;Choi, Doo-Ho;Ahn, Song-Vogue;Kang, Jin-Oh;Kim, Eun-Seog;Park, Won;Ahn, Seung-Do;Yang, Dae-Sik;Yun, Hyong-Geun;Chung, Eun-Ji;Chie, Eui-Kyu;Pyo, Hong-Ryull;Hong, Se-Mie
    • Radiation Oncology Journal
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    • v.26 no.4
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    • pp.289-294
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    • 2008
  • Purpose: To improve the quality of the statistical analysis of papers published in the Journal of the Korean Society for Therapeutic Radiology and Oncology (JKOSTRO) by evaluating commonly encountered errors. Materials and Methods: Papers published in the JKOSTRO from January 2006 to December 2007 were reviewed for methodological and statistical validity using a modified version of Ahn's checklist. A statistician reviewed individual papers and evaluated the list items in the checklist for each paper. To avoid the potential assessment error by the statistician who lacks expertise in the field of radiation oncology; the editorial board of the JKOSTRO reviewed each checklist for individual articles. A frequency analysis of the list items was performed using SAS (version 9.0, SAS Institute, NC, USA) software. Results: A total of 73 papers including 5 case reports and 68 original articles were reviewed. Inferential statistics was used in 46 papers. The most commonly adopted statistical methodology was a survival analysis (58.7%). Only 19% of papers were free of statistical errors. Errors of omission were encountered in 34 (50.0%) papers. Errors of commission were encountered in 35 (51.5%) papers. Twenty-one papers (30.9%) had both errors of omission and commission. Conclusion: A variety of statistical errors were encountered in papers published in the JKOSTRO. The current study suggests that a more thorough review of the statistical analysis is needed for manuscripts submitted in the JKOSTRO.

Incidence and Spectrum of Chromosomal Abnormalities associated with Spontaneous Abortions in Korea: 470 Products of Conception over a Period of 6 Years (2005-2010) (국내 자연유산에 의한 수태산물 핵형분석에서 관찰된 염색체 이상의 발생율과 유형: 6년(2005-2010)간 수태산물 470예 분석)

  • Han, Sung-Hee;An, Jeong-Wook;Yang, Young-Ho;Kim, Young-Jin;Cho, Han-Ik;Lee, Kyoung-Ryul
    • Journal of Genetic Medicine
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    • v.8 no.1
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    • pp.44-52
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    • 2011
  • Purpose: Cytogenetic analysis of spontaneous abortions (SABs) provides valuable information to establish the causes of fetal loss, information that is essential to provide accurate reproductive and genetic counseling couples. Such analysis also provides information on the frequencies and types of chromosomal abnormalities and associated risks of recurrence. However, there have only been a few reports of chromosomal abnormalities in small samples of SABs in the Korean population. Here, we report the incidence and spectrum of chromosomal abnormalities for cases of 470 SAB in Korea. Material and Methods: Between 2005 and 2010, a total of 470 products of conception (POC) resulting from SABs were submitted to our laboratory for cytogenetic analysis from various medical sites in Korea. The incidences and types of specific chromosomal abnormalities were determined. The abnormalities were distinguished by gestational age at the time of SAB and by maternal age. Results: The frequency of chromosomal abnormalities in POCs was 54.3% (255/470), including 228 (89.3%) numerical and 27 (10.7%: 3 balanced and 24 unbalanced) structural abnormalities. Among the numerical abnormalities, trisomy was predominant (67.0%), followed by monosomy X (12.5%), polyploidy (8.2%), triple X (0.8%), and autosomal monosomy (0.8%). The overall sex ratio (male: female) among the 470 POCs with normal and abnormal karyotypes were 0.58 and 0.65, respectively. Trisomies were identified for each autosome, with the exceptions of 1, 3, and 19. Among the 171 autosomal trisomies, trisomy 16 was the most common (19.9%), followed by trisomy 22 (13.5%), trisomy 21 (12.3 %), trisomy 15 (9.9%), and trisomies 18 and 13 (5.3%). The frequency of chromosomal abnormalities decreased with gestational age and increased with maternal age, but only because of increases in trisomies and complex abnormalities. Conclusions: We have presented a large collection of cytogenetic data for SABs collected during the past 6 years and provided a database for prenatal genetic counseling of parents who have experienced SABs in Korea.