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Imaging Features of Duodenal Adenocarcinoma in a Dog (개에서 발생한 십이지장 샘암종)

  • Jung, Mi-Ae;Lee, Min-Su;Lee, In-Hye;Lee, Ah-Ra;Park, Soo-Won;Lim, Chae-Young;Park, Heem-Young;Eom, Ki-Dong
    • Journal of Veterinary Clinics
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    • v.27 no.5
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    • pp.593-599
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    • 2010
  • A seven-year-old, castrated male Basset hound weighing 21.1 kg was presented for investigation of anorexia, lethargy, weight loss, melena and vomiting for 4 months. In laboratory findings, microcytic hypochromic anemia was identified, and other results were within a normal reference range. On the plain radiographs, soft tissue opacity was increased in the descending duodenal region; and on the contrast radiographs, ulcerative changes were identified in the entire segment of descending duodenum. Ultrasonographic findings included increased duodenal wall thickness and duodenal wall layering was lost. Endoscopy revealed irregular mucosal surface and luminal narrowing of the descending duodenum. There was concentrically thickened descending duodenum on the computed tomography. And the wall of the descending duodenum showed heterogenous enhancement after contrast agent injection. On histopathological findings, both chronic inflammation with mucosal proliferation and neoplastic changes with multiple small glandslike structures invading into the submucosa were identified. Based on these findings, presented case was diagnosed as an annular form duodenal adenocarcinoma. After 13 months of supportive medical treatment, the patient was expired. The purpose of this case report was to describe the duodenal adenocarcinoma in a dog.

Seasonal and Regional Concentrations of Chemical Composition in Rainwater in Daegu Area (대구지역의 빗물 중 화학적 성분의 계절별 및 지역별 농도분포)

  • Song, Hee-Bong;Lee, Eun-Kyeong;Jung, Dong-Sook;Kim, In-Ok;Lee, Myeong-Sug;Kwon, Byoung-Youne;Lee, Kyoung-Chool
    • Journal of Korean Society of Environmental Engineers
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    • v.28 no.5
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    • pp.522-526
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    • 2006
  • To investigate the characteristics of rainwater in Daegu area, parameters such as pH, electrical conductivity, TOC, TIC and TC were analyzed on 34 samples from January to December 2005. Results revealed that higher values were measured in winter than in summer. Furthermore samples that originated from industrial and commercial areas had higher chemical concentrations and conductivity as compared with those from residential and reference areas. Seldom acid-rain occurrence was recorded(27.2%) as compared with non-acid precipitation(72.8%) incidence. Also higher organic carbon fraction(TOC) was detected(72.5%) than inorganic form(TIC)(27.5%) in terms of component ratio with TC. During frequent rainfalls, the concentration of chemicals was decreased to a degree. Conversely, lower rate of rainfall gave out higher chemical values. Thereby the improvement of air qualify in 2005 compare with 2003 report was influenced by the environment authorities' efforts to reduce air pollutions and various factors by the depression of the region's economy.

Biodegradability of porous Calcium Polyphosphate (다공질 Calcium Polyphosphate의 생분해성에 관한 연구)

  • Yang, Seung-Min;Lee, Young-Kyoo;Han, Eun-Young;Kim, Seok-Young;Kye, Seung-Beom;Lee, Seung-Jin;Lee, Yong-Moo;Ku, Young;Han, Soo-Boo;Chung, Chong-Pyoung;Choi, Sang-Mook;Rhyu, In-Chul
    • Journal of Periodontal and Implant Science
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    • v.31 no.3
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    • pp.555-564
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    • 2001
  • The purpose of this study is to evaluate the bioresorbability of Calcium Polyphosphate added with $Na_2O$ and chitosan. Though calcium phosphate ceramics meet some of the needs for bone replacement, they have some limitation of unresorbability and fibrous encapsulation without direct bone apposition during bone remodelling. To solve these problem, we developed a new ceramic, calcium polyphosphate(CPP), and report the biologic response to CPP in extraction sites of beagle dog. Porous CPP granules were prepared by condensation of anhydrous $Ca(H_2PO_4)_2$ to form non-crystalline $Ca(PO_3)_2$. CPP granules added with $Na_2O$ and chitosan were implanted in extraction sockets and histologic observation were performed at 12 weeks later. Histologic observation at 12 weeks revealed that CPP matrix were mingled with and directly apposed to new bone without any intervention of fibrous connective tissue. CPP granules added with chitosan were well adatped without any adverse tissue reaction and resorbed slowly and spontaneously. CPP granules added with $Na_2O$ and chitosan show multinucleated giant cells and osteoblast-like cells around grafted material and newly formed bone. This result revealed that CPP, regardless of its additive component, had a high affinity for bone and had been resorbed slowly. From this results, it was suggested that CPP is promising ceramic as a bone substitute and addition of $Na_2O$ and chitosan help biodegradation. In further study , it will be determined which concentration of $Na_2O$ help biodegradation and the other additive components increase the degradation rate.

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A Case of Pneumothorax Caused by Cystic Lung Metastasis of Angiosarcoma (혈관육종의 낭성 폐전이에 의한 기흉 1예)

  • Lee, Chan Joo;Choi, Jun Jeong;Jeon, Han Ho;Jung, Kyung Soo;Park, Byung Hoon;Park, Seon Cheol;Shin, Sang Yun;Chung, Wou Young;Byun, Min Kwang;Moon, Ji Ae;Kim, Young Sam;Kim, Se Kyu;Chang, Joon;Kim, Sung Kyu;Park, Moo Suk
    • Tuberculosis and Respiratory Diseases
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    • v.64 no.5
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    • pp.374-378
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    • 2008
  • Angiosarcoma is a rare but highly malignant tumorthat usually arises in the scalp or face of elderly males. Distant metastases favor the lung, liver, lymph nodes and skin. Metastatic pulmonary angiosarcoma commonly takes the form of a nodule but can sometimes appear as a thin-walled cyst. We report a case of 65 years-old male with a spontaneous pneumothorax, who underwent excision and radiotherapy for an angiosarcoma of the scalp 2 years ago. A chest CT scan revealed multiple cysts in the lung. The video-assisted thoracoscopic lung biopsy demonstrated subpleural cysts without tumor cells. A skin biopsy of the scalp showed an angiosarcoma. This case was diagnosed as a recurrence of an angiosarcoma with a supposed lung metastasis. This case suggests that a spontaneous pneumothorax in elderly people may be secondary to a pulmonary metastasis from an angiosarcoma of the scalp.

A Study on managing Electric Application in Family-Mainly Refrigerator- (가정의 전기기기 관리에 관한 연구)

  • 문숙재;이재희
    • Journal of Families and Better Life
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    • v.1 no.2
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    • pp.43-57
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    • 1983
  • The purpose of the study, was to investigate Housewives behavior on how to buy refrigerators and how to use them. Besides, their knowledge and keeping ability of electricity and refrigerator is estimated according to regional differences, their ages, their educational courses, and their income. In the report, W e can see if it is related to the years of married life, numbers of the family, having jobs or not, and numbers of marketing a week. The subjects were 675 mothers of the students in the selected schools, at Seoul, Cheongjoo, and Kwesan gun. They answered to the questionnaire devised for the study. their answers were analyzed in percent to grasp their general trend of electricity and electric Appliance. Chi-square test and F-test are chosen to grasp the Cor-relationships between the related variables. The results are as follows: 1) The average rate of possesing the refrigerators is 84.06%. It shows us that the housewives in Seoul possess the more refrigerators than those in other areas. At ages, form 30 to 40 aged women gave the most refrigerators than any other ages women. It reveals us the high income and high educational housewives have high rate of possessing refrigerators. 2) They answered that they purchased the refrigerators by necessity. we can see their motivation of purchasing them is very reasonable. However, we can see that they do not manage the refrigerators well, because the rate of using them during four seasons is only 12.34%, An age of 20year old housewives mostly purchased the refrigerators at the time of marriage. The women who bought them after marriage answered that they mostly took a consultation with their husbands when they bought the refrigerators. They regarded the trade marks of the manufactures and size of the refrigerators, as they bought them. And most of them bought the refrigerators for cash. 3)At homes in Seoul, the kinds of retained foods in the refrigerator are more than those of the house in the city and in the agricultural town. The high income and high educational housewives tend to retain the more kinds of foods. But there are no significant differences between the essential variables such as the numbers of the family, the housewives having jobs or not, and the numbers of marketing. 4)Generally their knowledge on electricity and the refrigerator is very low. However, it shows the statistically significant differences. the housewives in Seoul have more information about refrigerator than the housewives in agricultural town. At ages , the women less than 29 years old have more information about the refrigerator, and the woman who had university education and high income tend to know much about the refrigerator. 5) The keeping ability of the refrigerator is very good, and there are no significant differences among variables. And also it shows that there is no correlationship between their knowledge and their keeping ability.

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Highly sensitive and selective detection of cyanide in aqueous solutions using a surface acoustic wave chemical sensor (표면음향파 화학센서를 이용한 수용액 중 시안화이온의 선택적인 고감도 검출)

  • Lee, Soo Suk
    • The Journal of the Acoustical Society of Korea
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    • v.35 no.6
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    • pp.473-479
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    • 2016
  • We report a highly selective and sensitive 200 MHz Surface Acoustic Wave (SAW) sensor that can detect cyanide ion in aqueous solution using surface immobilized thioester molecules in combination with gold nanoparticles (AuNPs). To construct the sensor device, a monolayer of thioester compound was immobilized on the SAW sensor surface. At the sensor surface, hydrolysis of thioester group by nucleophilic addition of cyanide occurred and the resulting free thiol unit bound to AuNP to form thiol-AuNP conjugate. For the signal enhancement, gold staining signal amplification process was introduced subsequently with gold (III) chloride trihydrate and reducing agent, hydroxylamine hydrochloride. The SAW sensor showed a detection ability of $17.7{\mu}M$ for cyanide in aqueous solution and demonstrated a saturation behavior between the frequency shift and the concentration of cyanide ion. On the other hand, our SAW sensor had no activities for other anions such as fluoride ion, acetate ion and sulfate ion, moreover, no significant interference observed by other anions. Finally, all the experiments were carried out in-house developed sensor and fluidics modules to obtain highly reproducible results.

The Occlusal Evaluation and Treatment Planning for Prosthodontic Full Mouth Rehabilitation (보철학적 교합 재구성을 위한 교합진단과 치료계획)

  • Lee, Seung-Kyu;Lee, Sung-Bok;Choi, Dae-Gyun
    • Journal of Dental Rehabilitation and Applied Science
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    • v.16 no.2
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    • pp.149-159
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    • 2000
  • Occlusal disease is comparable to periodontitis in that it is generally not reversible. Occlusal disease, however, like periodontitis, often maintainable. It does itself to treatment and when restorative dentistry is utilized it becomes, in that sense, reversible. Moreover, a systematized and integrated approach will lead to a prognosis that is favorable and predictable. This approach facilitates development of optimum oral function, comfort, and esthetics, resulting in a satisfied patient. Such a systematized approach consists of four logical phase : (1) patient evaluation, (2) comprehensive analysis and treatment planning, (3) integrated and systematic reconstruction, and (4) postoperative maintenance. An integrated treatment plan is first developed on one set of diagnostic casts, properly mounted on a semiadjustable articulator using jaw relationship records. This is accomplished by using wax to make reconstructive modifications to the casts. These modified casts become the blueprint for planned occlusal changes and the fabrication of provisional restorations. The treatment goals are : (1) comfortably functioning temporomandibular joints and stomatognathic musculature, (2) adherence to the basic principle of occlusion advocated by Schuyler, (3) anterior guidance that is in harmony with the envelope of function, (4) restorations that will not violate the patient's neutral zone. This report shows the treatment procedures for a patient whose mandibular position has been altered due to posterior bite collapse. Migration of the maxillary anterior teeth had occurred, and the posterior occlusal contacts showed pathologic interference. Precise diagnosis using mounted casts was executed and prosthodontic reconstruction by the aid of an unconventional orthodontic correction on maxillary flaring was planned. An unconventional orthodontic correction can be accomplished by using preexisting natural teeth, which can be modified for use in active tooth movement or splinted together for orthodontic anchorage. This technique has an advantage over conventional fixed appliance orthodontic therapy because it can accomplish tooth movement concurrently with restorative and periodontal therapy. On occasion, minor tooth movement can be necessary to achieve the optimum occlusal scheme, crown form, and tooth position for the forces of occlusion to be displaced down the long axis of the periodontally compromised teeth. Once the occlusion, periodontal health, and crown contours for the provisional splinted restoration are acceptable, the final splinted restoration can be similarly fabricated, and it becomes an excellent orthodontic retainer.

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Occlusal Adjustment and Prosthodontic Reconstruction on the Open-bite Patient. - Intentional Decrease of Occlusal Vertical Dimension - (자연치 교합조정에 의한 전치, 구치 개교합의 보철적 수복 - 수직고경의 의도적 감소증례)

  • Lee, Seung-Kyu;Kwon, Kung-Rock;Lee, Sung-Bok;Choi, Dae-Gyun
    • Journal of Dental Rehabilitation and Applied Science
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    • v.16 no.2
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    • pp.133-147
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    • 2000
  • A well-planned, precise occlusal adjustment of natural teeth has some distinct advantages over other forms of occlusal therapy. It should be emphasized, however, that an occlusal adjustment is an irreversible procedure and has definite contraindications in some mouths. Generally, the treatment methods for the patients that has open-bite will be following as below. : (1) Use of removable orthopedic repositioning appliance, (2) Orthodontics, (3) Full or partial reconstruction of the dentition, (4) Orthognathic surgical procedure, (5) Occlusal adjustment of the existing natural teeth, (6) Any combination of the above. Above all, the advantages of occlusal adjustment of natural teeth are : (1) the patient is more able to adapt to the changes in jaw position and posture; (2) the phonetic or speaking ability of the patient is not significantly changed and usually is improved; (3) the esthetics of the natural teeth is not altered and often is better; (4) the hygiene of the individual teeth is easily maintained; and (5) the functional usage of the teeth as cutting and chewing devices is markedly improved. The objective of an occlusal adjustment, as with any form of occlusal therapy, is to correct or remove the occlusal interferences, or premature contacts, on the occluding parts of the teeth which prevent a centric relation closure of the mandible. A systematic, disciplined approach can be followed in treatment, the objectives should be listed. They are : (1) Centric relation occlusion of the posterior teeth. (2) Proper "coupling" of the anterior teeth. (3) An acceptable disclusive angle of the anterior teeth in harmony with the condylar movement patterns. (4) Stability of the corrected occlusion. (5) Resolution of the related symptoms. For the patient with open-bite on anterior and posterior teeth, this case report shows the treatment methods in combination the fixed prosthesis with the selective cutting of the natural teeth. Occlusal adjustment is no longer an elective procedure but a mandatory one for patients requiring restorations and those in treatment for TMD dysfunctions or those whose dentitions show signs of occlusal trauma. Occlusal adjustment is essential for all who do not display the above lists.

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Solid-phase PEGylation for Site-Specific Modification of Recombinant Interferon ${\alpha}$-2a : Process Performance, Characterization, and In-vitro Bioactivity (재조합 인터페론 알파-2a의 부위 특이적 수식을 위한 고체상 PEGylation : 공정 성능, 특성화 및 생물학적 활성)

  • Lee, Byung-Kook;Kwon, Jin-Sook;Lee, E.K.
    • KSBB Journal
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    • v.21 no.2
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    • pp.133-139
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    • 2006
  • In 'solid-phase' PEGylation, the conjugation reaction occurs as the proteins are attached to a solid matrix, and thus it can have distinct advantages over the conventional, solution-phase process. We report a case study: rhIFN-${\alpha}$-2a was first adsorbed to cation exchange resin and then N-terminally PEGylated by aldehyde mPEG of 5, 10, and 20 kD through reductive alkylation. After the PEGylation, salt gradient elution efficiently recovered the mono-PEGylate in a purified form from the unwanted species such as unmodified IFN, unreacted PEG, and others. The mono-PEGylation and its purification were integrated in a single chromatographic step. Depending on the molecular weight of the mPEG aldehyde used, the mono-PEGylation yield ranged 50-64%. We could overcome the major problems of random, or uncontrollable, multi-PEGylation and the post-PEGylation purification difficulties associated with the solution-phase process. N-terminal sequencing and MALDI-TOF MS confirmed that a PEG molecule was conjugated only to the N-terminus. Compared with the unmodified IFN, the mono-PEGylate showed the reduced anti-viral activity as measured by the cell proliferation assay. The bioactivity was reduced more as the higher molecular weight PEG was conjugated. Immunoreactivity, evaluated indirectly by antibody binding activity using a surface plasmon resonance biosensor, also decreased. Nevertheless, trypsin resistance as well as thermal stability was considerably improved.

The external benefit of combustible waste-to-energy: A contingent valuation study (가연성 폐기물 에너지화의 외부편익 : 조건부 가치측정법의 적용)

  • Lim, Seul-Ye;Kim, Ho-Young;Yoo, Seung-Hoon
    • Journal of Energy Engineering
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    • v.22 no.3
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    • pp.270-282
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    • 2013
  • Combustible waste into energy policy is an effective method to respond to climate change and depletion of fossil fuels. Combustible waste into energy is the process of generating energy in the form of electricity and/or heat from the combustible waste such as vinyl, paper and plastic. This study tries to estimate the external benefit of enhancing the ratio of combustible waste into energy to primary energy from 1.89% to 5% using contingent valuation(CV) method. To this end, we report the results from a CV survey to elicit the willingness to pay (WTP) for combustible waste into energy. A CV survey of 500 households was conducted in the Seoul by using person-to-person interviews. Thus, the procedures of applying and the findings from the one-and-one-half bounded dichotomous choice spike model used to deal with the zero WTP responses are provided in the paper. The results show that the average WTP is estimated to be 2,724 won per household per month and statistically significant at the 5% level. Expanding the value to the Seoul gives us an aggregate value of 13.7 billion won per year.