• 대한약침학회지
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• 제20권2호
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• pp.119-126
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• 2017

Objectives: Semecarpus anacardium Linn. is a plant well-known for its antimicrobial, antidiabetic and anti-arthritic properties in the Ayurvedic and Siddha system of medicine. This has prompted the screening of this plant for antibacterial activity. The main aims of this study were to isolate compounds from the plant's seeds and to evaluate their antibacterial effects on clinical bacterial test strains. Methods: The n-butanolic concentrate of the seed extract was subjected to thin layer chromatography (TLC) and repeated silica gel column chromatography followed by elution with various solvents. The compound was identified based on observed spectral (IR, $^1H$ NMR, $^{13}C$ NMR and high-resolution mass spectrometry) data. The well diffusion method was employed to evaluate the antibacterial activities of the isolated acyclic isoprenoid compound (final concentration: $5-15{\mu}g/mL$) on four test bacterial strains, namely, Staphylococcus aureus (MTCC 96), Bacillus cereus (MTCC 430), Escherichia coli (MTCC 1689) and Acinetobacter baumannii (MTCC 9829). Results: Extensive spectroscopic studies showed the structure of the isolated compound to be an acyclic isoprenoid ($C_{21}H_{32}O$). Moreover, the isoprenoid showed a remarkable inhibition of bacterial growth at a concentration of $15{\mu}g/mL$ compared to the two other doses tested (5 and $10{\mu}g/mL$) and to tetracycline, a commercially available antibiotic that was used as a reference drug. Conclusion: The isolation of an antimicrobial compound from Semecarpus anacardium seeds validates the use of this plant in the treatment of infections. The isolated compound found to be active in this study could be useful for the development of new antimicrobial drugs.

• Clinics in Shoulder and Elbow
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• 제1권1호
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• pp.19-25
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• 1998

Appropriate clinical examination and imaging may lead to early diagnosis and treatment of the shoulder impingement syndrome, thus preventing progressing to a complete tear of rotator cuff. The impingement syndrome was caused by repeated entrapment and compression of supraspinatus tendon between the proximal end of humerus inferiorly, particullary its greater tuberosity. and one or m <)re component of coracoacromial arch superiorly. The purpose of this study is to critically, evaluate the result of twenty-five consecutive subacromial decompression with impingement syndrome and to assess the diagnostic accuracy of MR imaging by using oblique coronal and oblique sagittal plan. These patients were treated by arthroscopic subacromial decompression after their pains failed to improve with conservative therapy over three month. The average follow up was 25 month(range, 12 to 50). The mean age was 43 year old. The results were rated based on subjective response and the UCLA shoulder rating scale of the result. Ten patients(40%) were rated as excellent, 11patients(44%) were good. while four patients(16%) were fair. Radiologic evaluation suggested that the oblique sagittal plan of MRI can be helpful in evaluation of bony and soft-tissue structure of the coracoacromial arch and determining depth of bony resection. There were no infection or neurovascular injury. In reviewing our result, it appears that the arthroscopic subacromial decompression can be successful sugery for shoulder impingement syndrome and diagnostic accuracy of supplimentary oblique sagittal view of MRI was relatively higher than oblique coronal view alone for apprqpriate surgical plan.

• Journal of Preventive Medicine and Public Health
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• 제49권5호
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• pp.260-274
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• 2016

Objectives: Previous epidemiological studies about oxidative stress and depression are limited by hospital-based case-control design, single-time measurements of oxidative stress biomarkers, and the small number of study participants. Therefore, in this study, we analyzed the association between biomarker of oxidative stress and depressive symptom scores using repeatedly measured panel data from a community-dwelling elderly population. Methods: From 2008 to 2010, a total of 478 elderly participants residing in Seoul, Korea, were evaluated three times. Participants underwent the Korean version of the Short Form Generic Depression Scale (SGDS-K) test for screening depression, and urinary malondialdehyde (MDA) levels were measured as an oxidative stress biomarker. We used a generalized estimating equation with a compound symmetry covariance structure to estimate the effects of oxidative stress on depressive symptom scores. Results: A two-fold increase in urinary MDA concentration was significantly associated with a 33.88% (95% confidence interval [CI], 21.59% to 47.42%) increase in total SGDS-K scores. In subgroup analyses by gender, a two-fold increase in urinary MDA concentration was significantly associated with increased SGDS-K scores in both men and women (men: 30.88%; 95% CI, 10.24% to 55.37%; women: 34.77%; 95% CI, 20.09% to 51.25%). In bivariate analysis after an SGDS-K score ${\geq}8$ was defined as depression, the third and the fourth urinary MDA quartiles showed a significantly increased odds ratio(OR) of depression compared to the lowest urinary MDA quartile (third quartile OR, 6.51; 95% CI, 1.77 to 24.00; fourth quartile OR, 7.11; 95% CI, 1.99 to 25.42). Conclusions: Our study suggests a significant association between oxidative stress and depressive symptoms in the elderly population.

• Applied Biological Chemistry
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• 제4권
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• pp.23-28
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• 1963

1. 등전씨(藤田氏)의 Ether-alkali partition extraction법(法)을 개량(改良)하여 Capsaicin을 순수(純粹)하게 분리(分離)하여 정량표준곡선(定量標準曲線)을 얻었다. 2. Soxhlet장치(裝置)를 사용(使用)하여 Ether-Acetone(3:1) 혼합용매(混合溶媒)로 Capsaicin을 추출(抽出)한 후(後) 58% Methanoldmf 전개제(展開劑)로 하는 paper partition chromatography에 의(依)하여 불순물(不純物)로부터 Capsaicin을 순수(純粹)하게 분리(分離)하였다. 3. Diazobenzenesulphonic acid를 발색제(發色劑)로 사용(使用)하는 Schulte-Kruger 변법(變法)에 약간(若干) 개량(改良)을 가(加)하여 각품종별(各品種別) 고추중(中) Capsaicin 함량(含量)을 측정(測定)하였다.

• 한국전산구조공학회논문집
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• 제22권2호
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• pp.173-179
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• 2009

축소시스템은 반복적인 계산이 요구되는 문제에서 매우 유용하게 적용될 수 있는 해석 기법이다. 최근에는 영역분할 기법과의 연동을 통해 축소시스템의 효율성이 향상되었다. 그러나 전체 도메인이 몇 개의 영역으로 분할될 때 구속조건이 부과되지 않는 영역이 만들어지게 된다. 각 부영역에서 축소시스템을 구축하기 위해서는 주자유도가 선정되어야 하고, 이를 위해서는 리츠벡터를 추출해야 한다. 리츠벡터 계산은 구속조건이 부과된 부영역에서는 일반적인 정적해석을 통해 가능하나, 경계조건이 부과되지 않은 부영역에서는 의사역행렬을 이용해야 한다. 일반적으로 의사역행렬의 사용은 상당한 계산시간과 전산자원을 필요로 하는 문제점이 있다. 본 연구에서는 이 문제점을 개선하기 위해 축소 의사역행렬 도입을 제안한다. 이 방법은 정적 축소방법을 기초로 축소 의사역행렬을 구축하여 축소된 리츠벡터 정보를 추출하고, 변환관계를 통해 전체 리츠벡터 정보를 구한다. 수치예제에서는 일반적인 의사역행렬 계산시간 및 고유치 해석 결과의 비교를 통해 제안방법의 효율성과 신뢰성을 검증한다.

• 한국도로학회논문집
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• 제9권1호
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• pp.47-56
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• 2007

교통하중하의 포장구조에 대한 설계나 비선형 해석에 있어 도로하부 재료의 회복변형 특성이 활용되고 있다. 그러나 국내에서의 관련 연구가 매우 미진한 실정이다. 또한 매우 제한적인 범위의 자료만이 노상토의 회복탄성계수를 추정하는데 활용되고 있다. 이에 본 논문에서는 시험도로 입상 노상토를 대상으로 비선형 특성을 알아보기 위하여 반복재하 회복탄성계수 시험을 수행하였다. 현장조건을 반영하여 함수비와 응력조건을 고려한 회복탄성계수 구성방정식을 제안하였다. 이를 통하여 응력조건을 고려한 회복탄성계수 예측모델과 적합한 응력의존 모델을 결정하고 계절적인 함수비 변화가 고려된 회복탄성계수 모델을 각각 비교하였다.

• 한국통신학회논문지
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• 제24권10B호
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• pp.1986-1994
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• 1999

본 논문에서는, 동영상에서 의미 있는 객체 영역을 추출하기 위해서, 첫 장의 영상 분할은 사람에 의해서 주어진 것으로 가정하고, 그 다음 프레임부터는 사람의 도움 없이 객체를 추적해 가는 반자동 방식의 이동체 추적 알고리즘을 제안한다. 제안하는 알고리즘은 계층적인 구조를 가지며, 각각의 계층에서는 seed 추출, watershed 알고리즘을 이용한 영상 분할, 영역 구분의 단계를 거쳐 영상 분할을 수행한다. 영역 구분 단계에서는, 순방향으로 추정된 움직임 벡터장으로부터 영역 분할의 판단 기준을 만들고 이를 이용하여 각각의 영역을 '객체 영역', '배경 영역', '불확실 영역'으로 구분한다. 이때, '불확실 영역'으로 구분된 영역들에 대해서는 좀 더 낮은 계층에서 위의 단계들을 반복하여 다시 수행하게 한다. 제안한 알고리즘은 컴퓨터 모의실험을 통해서 'Claire', 'Miss America', 'Akiyo', 'Mother and daughter'의 영상에서 바람직한 추적 결과를 나타냄을 확인하였다.

• 한국수산과학회지
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• 제34권5호
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• pp.556-562
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• 2001

본 연구에서는 비교적 성장이 빠르고 배양이 용이한 황갈편조 식물문 중 규조강에 속하는 P. tricornutum으로부터 선정하여 항 산화성 물질을 분리$\cdot$정제하여 물질의 구조를 밝혔다. P. tricornutum의 각 유기용매 추출물의 항산화성은 chloroform획분이 가장 좋았으며, 이 획분을 시료로 하여 silica gel column chromatography, PTLC 및 HPLC를 사용하여 항산화성 물질을 분리$\cdot$정제하였다. Silica gel column을 사용하여 분리된 획분의 항산화성은 dichloromethane: methanol (5: 1)로 용출시킨 획분에서 가장 높았으며, 이 획분의 PTLC 획분은 항산화성이 $20\%$ 증가하였다. 최종 정제된 물질의 $IC_50$값은 $8.3{\mu}g/mL$으로 화학적으로 합성된 항산화제인 BHT 및 BHA보다는 낮았지만 천연 항산화제인 $\alpha-tocopherol$보다는 다소 높게 나타났으며, 이 물질의 화학적 구조는 carotenoid류인 zeaxanthin으로 동정되었다.

• The Journal of Korean Physical Therapy
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• 제19권5호
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• pp.1-10
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• 2007

Purpose: Leg-crossing sitting is very common for men and woman. No solid evidence exists for either a beneficial or a detrimental effect of this posture. This study investigated the change of activities of trunk muscles between the normal group and the low back pain group during various leg-crossing positions. Methods: The subjects were consisted of 10 subjects who don't have low back pain and 10 subjects who have low back pain. In this study, we used electromyography(EMG) to evaluate the activities of both the trunk muscles (rectus abdominis, external oblique, internal oblique, and multifidus) during various leg-crossing positions (up-right, leg-crossing, tailor-crossing, and ankle-crossing). We analyzed the data by using repeated one way ANOVA. Results: In normal group, there were increased in EMG activities of trunk muscles, but no significant differences during leg-crossing positions. In back pain group, there were increased in EMG activities of right external oblique, left. internal oblique, and both multifidus muscles in leg-crossing and tailor-crossing position, but no significant differences during leg-crossing positions. There was no significant difference of muscle activity of trunk muscles between the back pain group and the normal group. Conclusion: We suggest that low back pain people who have weak muscles of rectus abdominis, external and internal oblique are often experienced in leg-crossing posture than normal. To compensate this unstability of trunk, leg-crossing posture is substituted passive structure for activities of active muscle.

• 복식
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• 제64권7호
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• pp.97-113
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• 2014

The study aims to determine the significance and characteristics of self-similarity inherent in natural objects or phenomena, the existence of self-similarity in design created by fashion designers, and the traits and internal significance implied in self-similarity and their effects on fashion. The subject of the study is Viktor & Rolf, and the scope of the study is the collections created from 2001 to 2014, which include designs implemented in their early years and those unveiled in the media. Self-similarity means attributes of a fractal structure appearing without change in the original form, even after modification of scale or direction in terms of shape or phenomena. As self-similarity is applied to the arts and design sectors, it leads people to pay attention to fundamental characteristics and intrinsic forms as a factor of expressing a unique creative world. Analysis of Viktor & Rolf collections generated ribbons, overlapping/juxtaposition, side decorations and exaggerated design elements as basic units of self-similarity. These factors had self-similarity rates as high as 84%. Self-similarity was established as design elements formed in the incipient stage were repeated in a certain form, and continued for a long period of time. It served as an element that recognizes design and a fashion designer at the same time. Characteristics of self-similarity appearing in Viktor & Rolf collections can be summarized as homeostasis based on an equivalent relationship, balance based on self-organization, reducibility into essential elements, and uniqueness based on odd shapes. These characteristics influenced the pursuit of consistent brand image, the maintenance of a fashion designer's creative world, the formation of styles and the expression of a fashion designer's identity.