• Journal of the Korean Institute of Navigation
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• v.22 no.4
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• pp.31-36
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• 1998

The whistle is a very important information source for the safety navigation under foggy weather. But navigator has no concern about this, because it must be achived by human hearing sense and considered as a vague signal. If the range and relative bearing of signal source can be detected automatically, it would be very useful system for preventing marine casualties making a lot of economic loss and environment pollution. Before the algorithm of 2-dimensional sound source tracking system was reported. This paper describes the method that can obtain the time lag between three signals and the theory of cross-correlation analysis and subtraction method for cauculating the time lag by using the digital signal data sequences. And a series of experiments were carried out for various position of sound source in the range from 200cm to 530cm. As a result, we have recognized that sound source tracking system is possible to the sea field with improvement of position error.

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.973-977
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• 2004

A pneumatic cylinder used to sliding seal which seal the element one to another in relative motion. It is difficult to accuracy control because of adhesion phenomenon. To confirm this phenomenon, it is carried to friction force test and analysis for bellows type rodless cylinder. In the rodless cylinder of this type, friction force test is very important. Through the theoretical analysis of shock absorber obtained the optimal design of bellows type rodless cylinder. As the result of the friction force test, LM Guide type is suitable for work under low friction force.

• Structural Engineering and Mechanics
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• v.12 no.6
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• pp.615-632
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• 2001

Ductility of open piled wharves under reversed cyclic loads has been investigated. Experimental testing of five wharf models having a scale of about 1:4 was conducted under the application of horizontal reversed cyclic loading. The experiments were designed to focus on the horizontal ultimate load, ductility and failure mode of the considered wharf models. Nonlinear numerical analyses using the finite element method were also performed on numerical models representing the experimentally tested wharves. The results of the experimental tests showed that open piled wharves possessed favourable ductile behaviour and that their load bearing capacity did not depreciate until a ductility factor of 3 to 4 was reached. The numerical analysis showed that the relative rotation that took place at the joints between the steel piles and the R.C. beam was responsible for a considerable portion of the total horizontal deformation of the wharves. Therefore, it was concluded that introducing the joint stiffness in calculating the deformations of open piled wharves was important to achieve reasonable accuracy.

• Proceedings of the Korean Institute of Resources Recycling Conference
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• 2005.11a
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• pp.3-14
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• 2005

We Investigated minutely how the biosorption technology using algal biomass is opened in Canadian technology society. Making comparative study for relative technologies in views of overall unit operation cost, we could grasp next facts. - Algal biomass plays the competitive performance for various metals. - Algal biomass biosorbent is regenerated. - Reactor system is not and involved one. This means that algal biomass occupies the strong position as biosorbent. Especially, in North America, for the purpose of metal bearing wastewater treatment, 20 hundred million US dollars was appropriated a sum for the purchase of ion exchange resin. But it is only thirty million US dollars if algal biomass biosorbent is used on behalf of ion exchange resin. Furthermore, the expenses for same treatment can be cut down additively through metal recovery.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.1
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• pp.47-54
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• 2014

The aim of this study is to evaluate the effects of green tea polyphenol (GTP) on anticancer treatment with cisplatin (CP), using both an in vitro cell culture model and an in vivo mouse model of established breast tumor. Mouse breast cancer cells (EMT6) were treated with or without GTP and CP followed by determination of the cell viability using an MTT assay. The relative cell viability of CP treated EMT6 cells was 96% at a 20 ${\mu}g/mL$ concentration of cisplatin; however, in combination with GTP (50 ${\mu}g/mL$), the cell viability decreased to 20% at the same concentration of CP (20 ${\mu}g/mL$). For the in vivo study, EMT6 cells were inoculated into Balb/c mice for the establishment of a tumor-bearing mice model. The tumor-bearing mice were treated with CP (5 mg/kg. i.p.) with or without dietary GTP (0.2% drinking water). Tumor growth was monitored by a measurement of tumor size using a digital caliper, and nephrotoxicity was determined by enzymatic and histological examinations. The levels of p53 and caspase-3 in tumor tissues were examined by a Western blot. In tumor-bearing mice treated with GTP plus CP, the increment of tumor volume showed a significant reduction, compared with CP or GTP alone. The levels of p53 and cleaved caspase-3 (caspase-3/p17) in tumor tissues of tumor-bearing mice were increased by CP and GTP compared to CP alone. In CP treated tumor-bearing mice, ${\gamma}$-glutamyltranspeptidase (GGT) and alkaline phosphatase (AP) activities were decreased, and marked tubular necrosis and dilatation were observed in the kidney. CP-induced enzymatic and histopathological changes in the kidney of tumor-bearing mice were reduced by combinations of GTP with CP. The results of these experiments demonstrated that dietary GTP has a potentiating effect on CP anti-tumor activity and a protective effect against CP-induced renal dysfunction. Therefore, GTP may be used as a modulator in anticancer treatment with CP.

• Smart Structures and Systems
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• v.21 no.4
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• pp.421-433
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• 2018

Carbon fiber reinforced polymer (CFRP) cable has good mechanical properties and corrosion resistance. However, the anchorage of CFRP cable is a big issue due to the anisotropic property of CFRP material. In this article, a high-efficient bonding anchorage with novel configuration is developed for CFRP cables. The acoustic emission (AE) technique is employed to evaluate the performance of anchorage in the fatigue test and post-fatigue ultimate bearing capacity test. The obtained AE signals are analyzed by using a combination of unsupervised K-means clustering and supervised K-nearest neighbor classification (K-NN) for quantifying the performance of the anchorage and damage evolutions. An AE feature vector (including both frequency and energy characteristics of AE signal) for clustering analysis is proposed and the under-sampling approaches are employed to regress the influence of the imbalanced classes distribution in AE dataset for improving clustering quality. The results indicate that four classes exist in AE dataset, which correspond to the shear deformation of potting compound, matrix cracking, fiber-matrix debonding and fiber fracture in CFRP bars. The AE intensity released by the deformation of potting compound is very slight during the whole loading process and no obvious premature damage observed in CFRP bars aroused by anchorage effect at relative low stress level, indicating the anchorage configuration in this study is reliable.

• The Korean Journal of Cytopathology
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• v.7 no.2
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• pp.192-196
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• 1996

The principal significance of the urothelial changes caused by polyomavirus activation is in an erroneous diagnosis of urothelial cancer; however, the clue to their benign nature is the smooth structureless nuclear configuration and the relative paucity of affected cells. Though virologic studies and electron microscopy are usually needed to firmly establish the diagnosis, cytology is the most readily available and rapid means of establishing a presumptive diagnosis of human polyomavirus infection. A urine specimen of a 24-year-old man with hemorrhagic cystitis beginning two months after bone marrow transplantation for acute myeloblastic leukemia(M2) was submitted for cytologic evaluation. Cytologic findings revealed a few inclusion-bearing epithelial cells intermingled with erythrocytes, neutrophils, lymphocytes, and macrophages. Most of the inclusion-bearing fells had large, round to ovoid nuclei almost completely filled with homogeneous dark, basophilic inclusion. The chromatin was clumped along the periphery and the cytoplasm was mostly degenerated. The other cells exhibited irregular inclusions attached to the nuclear membrane surrounded by an indistinct halo. These findings were consistent with polyomavirus infection.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1255-1262
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• 2014

Background: The aim of the study was to investigate any associations between benign prostate hyperplasia (BPH) and single nucleotide polymorphisms (SNPs) in the VDR gene (FokI, BsmI, ApaI and Taq${\alpha}$I loci) and the CYP17 gene (MspA1I locus), as well as TA repeat polymorphism in SRD5A2 gene among Lebanese men. Materials and Methods: DNA extracted from blood of 68 subjects with confirmed BPH and 79 age-matched controls was subjected to PCR/PCR-restriction fragment length polymorphism analysis. The odds ra=tio (OR) of having a genotype and the relative risk (RR) of developing BPH for having the genotype were calculated and the alleles were designated risk-bearing or protective. Results: Our data indicated that the A and B alleles of the VDR ApaI and BsmI SNPs were highly associated with increased risk of BPH (p=0.0168 and 0.0002, respectively). Moreover, 63% of the controls compared to 43% of the subjects with BPH were homozygous for none of the risk-bearing alleles (p=0.0123) whereas 60% of the controls and 28% of the subjects with BPH were homozygous for two or more protective alleles (p<0.0001). Conclusions: For the first time, our study demonstrated that ApaI and BsmI of the VDR gene are associated with risk of BPH among Lebanese men. Our study also indicated that overall polymorphism profile of all the genes involved in prostate physiology could be a better predictor of BPH risk.

• BMB Reports
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• v.35 no.6
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• pp.637-641
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• 2002

Only one natural promoter that interacts with bacteriophage K11 RNA polymerase has so far been identified. To identify more, in the present study restriction fragments of the phage genome were individually assayed for transcription activity in vitro. The K11 genome was digested with two 4-bp-recognizing restriction enzymes, and the fragments cloned in pUC119 were assayed with purified K11 RNA polymerase. Eight K11 promoter-bearing fragments were isolated and sequenced. We report that the nine K11 promoter sequences (including the one previously identified) were highly homologous from -17 to +4, relative to the initiation site at +1. Interestingly, five had -10G and -8A, while the other four had -10A and -8C. The consensus sequences with the natural -10G/-8A and -10A/-8C, and their variants with -10G/-8C and -10A/-8A, showed nearly equal transcription activity, suggesting residues at -10 and -8 do not regulate promoter activity. Using hybridization methods, physical positions of the cloned promoter-bearing sequences were mapped on SalI-and KpnI-restriction maps of the K11 genome. The flanking sequences of six cloned K11 promoters were found to be orthologous with T7 or T3 genomic sequences.

• Steel and Composite Structures
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• v.23 no.2
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• pp.195-204
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• 2017

The effects of plaster on the behavior of single-story single-bay masonry-infilled steel frames under in-plane base accelerations have been experimentally investigated by a shake-table. Tested structures were made in a 1/3 scale, with realistic material properties and construction methods. Steel frames with high and low flexural rigidity of beams and columns were considered. Each type of frame was tested with three variants of masonry: (i) non-plastered masonry; (ii) masonry infill with conventional plaster on both sides; and (iii) masonry infill with a polyvinyl chloride (PVC) net reinforced plaster on both sides. Masonry bricks were made of lightweight cellular concrete. Each frame was firstly successively exposed to horizontal base accelerations of an artificial accelerogram, and afterwards, to horizontal base accelerations of a real earthquake. Characteristic displacements, strains and cracks in the masonry were established for each applied excitation. It has been concluded that plaster strengthens the infill and prevents damages in it, which results in more favorable behavior and increased bearing capacity of plastered masonry-infilled frames compared to non-plastered masonry-infilled frames. The load-bearing contribution of the adopted PVC net in the plaster was not noticeable for the tested specimens, probably due to relative small cross section area of fibers in the net. Behavior of masonry-infilled steel frames significantly depends on frame stiffness. Strong frames have smaller displacements than weak frames, which reduces deformations and damages of an infill.