• 전력전자학회논문지
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• 제14권2호
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• pp.142-149
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• 2009

본 논문은 단위 역률을 갖도록 직접 시비율 펄스폭 변조 방식으로 제어되는 3상 매트릭스 컨버터의 평형 및 불평형 부하시의 동작 특성을 고찰한다. 시스템의 해석으로부터 얻어진 중요하고 유용한 사실을 정리하면 다음과 같다. (1) 단위 역률 제어 알고리즘은 부하측의 변수에 의해서가 아니라 입력전압에 의하여 정해진다. (2) 평형 3상 부하가 리액티브 부하인 경우만 아니라면 입력측 역률을 1로 만들 수 있다. (3) 불평형 선형부하의 경우, 매트릭스 컨버터의 등가입력 특성은 비선형저항과 같다. (4) 입력 주파수와 출력 주파수가 특정한 관계를 가질 때, 입력측의 각상은 동일한 평균전력 분담률을 갖는다. 해석의 타당성과 유효성은 시뮬레이션과 실험결과를 통하여 검증하였다.

• The Korean Journal of Physiology and Pharmacology
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• 제11권3호
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• pp.85-88
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• 2007

Matrix metalloproteinases (MMPs) can degrade a wide range of extracellular matrix components. It has been reported that MMP-9 are activated after focal ischemia in experimental animals. (-)-Epigallocatechin-3-gallate (EGCG), a major constituent of green tea polyphenols, is a potent free radical scavenger and reduces the neuronal damage caused by oxygen free radicals. And it has been known that EGCG could reduce the infarction volume in focal brain ischemia and inhibit MMP-9 activity. To delineate the relationship between the anti-ischemic action and the MMP-9-inhibiting action of EGCG, we investigated the effect of EGCG on brain infarction and the activity of matrix metalloproteinase-9 induced by permanent middle cerebral artery occlusion (pMCAO) in ICR mice. EGCG (40 mg/kg, i.p. $15{\sim}30min$ prior to MCAO) significantly decreased infarction volume at 24 hr after MCAO. GM 6001 (50 mg/kg, i.p. $15{\sim}30min$ prior to MCAO), a MMP inhibitor, also significantly reduced infarction volume. In zymogram, MMP-9 activities began to increase at ipsilateral cortex at 2 hr after MCAO, and the increments of MMP-9 activities were attenuated by EGCG treatment. Western blot for MMP-9 also showed patterns similar to that of zymogram. These findings demonstrate that the anti-ischemic action of EGCG ire mouse focal cerebral ischemia involves its inhibitory effect on MMP-9.

• Archives of Pharmacal Research
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• 제28권11호
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• pp.1311-1316
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• 2005

To better define the relationship between dermal regeneration and wound contraction and scar formation, the effects of epidermal growth factor (EGF) loaded in collagen sponge matrix on the fibroblast cell proliferation rate and the dermal mechanical strength were investigated. Collagen sponges with acid-soluble fraction of pig skin were prepared and incorporated with EGF at 0, 4, and 8 $\mu$g/1.7 $cm^{2}$. Dermal fibroblasts were cultured to 80$\%$ confluence using DMEM, treated with the samples submerged, and the cell viability was estimated using MTT assay. A deep, $2^{nd}$ degree- burn of diameter 1 cm was prepared on the rabbit ear and the tested dressings were applied twice during the 15-day, post burn period. The processes of re-epithelialization and dermal regeneration were investigated until the complete wound closure day and histological analysis was performed with H-E staining. EGF increased the fibroblast cell proliferation rate. The histology showed well developed, weave-like collagen bundles and fibroblasts in EGF-treated wounds while open wounds showed irregular collagen bundles and impaired fibroblast growth. The breaking strength (944.1 $\pm$ 35.6 vs. 411.5 $\pm$ 57.0 Fmax, $gmm^{-2}$) and skin resilience (11.3 $\pm$ 1.4 vs. 6.5 $\pm$ 0.6 mJ/$mm^{2}$) were significantly increased with EGF­treated wounds as compared with open wounds, suggesting that EGF enhanced the dermal matrix formation and improved the wound mechanical strength. In conclusion, EGF-improved dermal matrix formation is related with a lower wound contraction rate. The impaired dermal regeneration observed in the open wounds could contribute to the formation of wound contraction and scar tissue development. An extraneous supply of EGF in the collagen dressing on deep, $2^{nd}$ degree-burns enhanced the dermal matrix formation.

• 치위생과학회지
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• 제22권2호
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• pp.99-107
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• 2022

Background: Obesity weakens acquired immunity and causes infection. This study aimed to investigate the relationship between the inflammatory markers in the gingival crevicular fluid and serum and periodontal bacteria in saliva through obesity control for 4 weeks. Methods: Forty-six subjects with a body mass index (BMI) of ≥23 kg/m² stayed in the camp for 4 weeks, followed by exercise and a low salt-low fat diet. Body size measurements, oral examinations, blood, saliva, and gingival crevicular fluid were collected before and after the program. C-reactive protein (CRP) in serum, matrix metalloproteinase (MMP)-8, MMP-9, and interleukin (IL)-1β in the gingival sulcus fluid were measured. After extracting bacterial genomic DNA from saliva, the presence of periodontal bacteria were detected using Taq probe. The relationship of each index before and after the program was analyzed through paired t-test and partial correlation analysis. Results: Campylobacter rectus (Cr) increased after the program, and there was no significant change in other bacteria. Serum CRP and Fusobacterium nucleatum (Fn), Aggregatibacter actinomycetemcomitans, Cr, ratio of Fn, and ratio of Cr had a positive relationship at baseline; however, the relationship was not significant after the program. Ratio of Prevotella intermedia had a positive relationship with MMP-9, MMP-8, IL-1β at baseline. Moreover, the ratio of Treponema denticola and the ratio of Tannerella forsythia showed a positive relationship with MMP-8, MMP-9, and IL-1β. The relationship between the ratio of Porphyromonas gingivalis and IL-1β showed a constant positive relationship at baseline and after the program. Conclusion: Obesity control program in subjects with a BMI of ≥23 kg/m² accompanied by diet and exercise did not affect the changes in periodontal bacteria itself, but changes in the relationship between periodontal bacteria and serum CRP, the relationship between the inflammatory index in the gingival crevicular fluid and periodontal bacteria was observed.

• 정보화정책
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• 제21권4호
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• pp.81-97
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• 2014

본 연구는 정보통신 기기 및 관련 서비스에 대한 소비자들의 구매행태를 분석하고, 다양한 정보통신 기기 및 서비스 간의 상관관계를 파악하고자 한다. 본 연구는 다양한 제품과 서비스의 다중선택 상황을 동시에 고려함으로써, 각 제품 및 서비스 그룹 내의 상관관계뿐만 아니라 그룹 간의 상관관계도 추가적으로 살펴보고자 한다. 분석자료는 소비자 설문조사를 통해 수집하였으며, 인구통계학 변수를 고려한 다변량 프로빗 모형(Multivariate Probit Model)과 분산-공분산 행렬(Variance-covariance Matrix)을 분석하기 위한 대안상수 모형(Alternative Specific Constant Model)을 각각 추정하였다. 또한 다차원척도 분석(Multi-dimensional Scaling Method)을 이용하여 제품 및 서비스 간의 관계도를 도식화하였으며, 다양한 정보통신 기기 및 서비스 간의 대체 또는 보완 관계를 도출하였다. 본 연구는 소비자들의 구매행태를 이해하고 예측함으로써 신제품과 서비스의 개발에 유용한 정보를 제공할 것으로 기대된다.

• Asian-Australasian Journal of Animal Sciences
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• 제13권2호
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• pp.137-148
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• 2000

This paper is based on the 9 goat colonies along the middle and lower Yellow River valley and 7 local goat colonies in the Northeast, Tibet and the Yangtze valley. After collecting the same data about the 22 goat colonies in China and other countries, it establishes and composes the matrix of fuzzy similarity relation describing the genetic similarities of different colonies. It also clusters 38 colonies according to their phylogenetic relationship. The establishment of the matrix and the cluster are effected in terms of the frequency of 18 loci and 43 allelomorphs in blood enzyme and other protein variations. The study proves that the middle Yellow River valley is one of the taming and disseminating centers of domestic goats in the South and East of Central Asia. Compared with other goat populations in this vast area, the native goat populations in the west of Mongolian Plateau, the Qinghai-Tibet Plateau and the middle Yellow River valley share the same origin. The colonies in the lower Yellow River valley and those in the middle valley, however, are relatively remote in their phylogenetic relationship. The native goat colonies in the southeast of Central Asia can be classified into two genetic groups: "East Asia" and "South Asia" and the colonies in Southeast Asia belong to either group.

• 한국재료학회지
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• 제30권5호
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• pp.231-238
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• 2020

The composition of martensite transformation in NiAl alloy is determined using pure nickel and aluminum powder by vacuum hot press powder metallurgy, which is a composition of martensitic transformation, and the characteristics of martensitic transformation and microstructure of sintered NiAl alloys are investigated. The produced sintered alloys are presintered and hot pressed in vacuum; after homogenizing heat treatment at 1,273 K for 86.4 ks, they are water-cooled to produce NiAl sintered alloys having relative density of 99 % or more. As a result of observations of the microstructure of the sintered NiAl alloy specimens quenched in ice water after homogenization treatment at 1,273 K, it is found that specimens of all compositions consisted of two phases and voids. In addition, it is found that martensite transformation did not occur because surface fluctuation shapes did not appear inside the crystal grains with quenching at 1,273 K. As a result of examining the relationship between the density and composition after martensitic transformation of the sintered alloys, the density after transformation is found to have increased by about 1 % compared to before the transformation. As a result of examining the relationship between the hardness (Hv) at room temperature and the composition of the matrix phase and the martensite phase, the hardness of the martensite phase is found to be smaller than that of the matrix phase. As a result of examining the relationship between the temperature at which the shape recovery is completed by heating and the composition, the shape recovery temperature is found to decrease almost linearly as the Al concentration increases, and the gradient is about -160 K/at% Al. After quenching the sintered NiAl alloys of the 37 at%Al into martensite, specimens fractured by three-point bending at room temperature are observed by SEM and, as a result, some grain boundary fractures are observed on the fracture surface, and mainly intergranular cleavage fractures.

• Journal of applied mathematics & informatics
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• 제30권3_4호
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• pp.365-380
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• 2012

Non-negative matrix factorization (NMF) is a very efficient method to explain the relationship between functions for finding basis information of multivariate nonnegative data. The multiplicative update (MU) algorithm is a popular approach to solve the NMF problem, but it fails to approach a stationary point and has inner iteration and zero divisor. So the elementwisely alternating projected gradient (eAPG) algorithm was proposed to overcome the defects. In this paper, we use the fact that the equilibrium point is stable to prove the convergence of the eAPG algorithm. By using a classic model, the equilibrium point is obtained and the invariant sets are constructed to guarantee the integrity of the stability. Finally, the convergence conditions of the eAPG algorithm are obtained, which can accelerate the convergence. In addition, the conditions, which satisfy that the non-zero equilibrium point exists and is stable, can cause that the algorithm converges to different values. Both of them are confirmed in the experiments. And we give the mathematical proof that the eAPG algorithm can reach the appointed precision at the least iterations compared to the MU algorithm. Thus, we theoretically illustrate the advantages of the eAPG algorithm.

• Wind and Structures
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• 제25권5호
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• pp.459-474
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• 2017

In this study an analytical expression is derived for the natural frequency of the wind turbine towers supported on flexible foundation. The derivation is based on a Euler-Bernoulli beam model where the foundation is represented by a stiffness matrix. Previously the natural frequency of such a model is obtained from numerical or empirical method. The new expression is based on pure physical parameters and thus can be used for a quick assessment of the natural frequencies of both the real turbines and the small-scale models. Furthermore, a relationship between the diagonal and non-diagonal element in the stiffness matrix is introduced, so that the foundation stiffness can be obtained from either the p-y analysis or the loading test. The results of the proposed expression are compared with the measured frequencies of six real or model turbines reported in the literature. The comparison shows that the proposed analytical expression predicts the natural frequency with reasonable accuracy. For two of the model turbines, some errors were observed which might be attributed to the difference between the dynamic and static modulus of saturated soils. The proposed analytical solution is quite simple to use, and it is shown to be more reasonable than the analytical and the empirical formulas available in the literature.

• 한국소음진동공학회논문집
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• 제14권3호
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• pp.236-243
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• 2004

In this paper a dynamic behavior of a simply supported cracked pipe conveying fluid with the moving mass is presented. Based on the Timoshenko beam theory, the equation of motion can be constructed by using the Lagrange's equation. The crack section is represented by a local flexibility matrix connecting two undamaged beam segments i.e. the crack is modelled as a rotational spring. This flexibility matrix defines the relationship between the displacements and forces across the crack section and is derived by applying fundamental fracture mechanics theory. And the crack is assumed to be in th first mode of fracture. As the depth of the crack and velocity of fluid are increased the mid-span deflection of the pipe conveying fluid with the moving mass is increased. As depth of the crack is increased, the effect of the velocity of the fluid on the mid-span deflection appears more greatly.