• Molecules and Cells
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• v.40 no.3
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• pp.169-177
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• 2017

Tissue-specific transcription is critical for normal development, and abnormalities causing undesirable gene expression may lead to diseases such as cancer. Such highly organized transcription is controlled by enhancers with specific DNA sequences recognized by transcription factors. Enhancers are associated with chromatin modifications that are distinct epigenetic features in a tissue-specific manner. Recently, super-enhancers comprising enhancer clusters co-occupied by lineage-specific factors have been identified in diverse cell types such as adipocytes, hair follicle stem cells, and mammary epithelial cells. In addition, noncoding RNAs, named eRNAs, are synthesized at super-enhancer regions before their target genes are transcribed. Many functional studies revealed that super-enhancers and eRNAs are essential for the regulation of tissue-specific gene expression. In this review, we summarize recent findings concerning enhancer function in tissue-specific gene regulation and cancer development.

• The Korean Journal of Food & Health Convergence
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• v.4 no.2
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• pp.1-5
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• 2018

Background: the self-regulating in adolescent's smokers as prevention is one of the lines of the work team in the consultation of Ceasing Tobacco. Objective: to identify the factors of risks that impact in the self-regulation to prevent the tobacco in adolescents. The investigation embraced one period from March 2017 to September 2018. Method: a descriptive study of traverse court was used. Registered to 31 students for sampling intentional non probabilistic, of an universe of 50 adolescent students. It was used empiric methods; clinical histories, interviews structured and the questionnaire. Conclusion: the female sex prevailed, where 54,8 % between the 12 to 19 years of age. Results: the incidence the factors of risks that impact in the self-regulation to prevent the tobacco in adolescents are the group contagion with 54,7 %, family problems for a 29,0 % and situational depression with 16,1 %, where it is necessary the self-regulation that should have the adolescents in the life.

• Korean Journal of Child Studies
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• v.38 no.1
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• pp.17-31
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• 2017

Objective: The purpose of this research was to examine the effects of parents' childhood attachment representations and parenting behavior in developing early childhood self-regulation, a developmental skill. Methods: This research was conducted with 171 preschoolers, 171 parent couples, and 22 teachers of 5-year-old classes in kindergartens and children's houses in Seoul. Results: First, there was significant correlation among parental childhood attachment representations, parenting behavior, and child self-regulation. Second, parental attachment representations and parenting behavior were shown to affect self-monitoring, a subvariable of self-regulation, and were influenced by maternal independence-oriented parenting behavior, maternal attachment representation, and parental attachment representation. As factors affecting self-control, a subvariable of self-regulation, they were influenced by maternal attachment representation, and maternal and paternal affectionate parenting behavior. Lastly, as factors affecting self-control, they were influenced by attachment representation to parents of origin, maternal affectionate parenting behavior, and maternal independence-oriented parenting behavior. Conclusion: This research revealed that parental childhood attachment representations and parenting behavior are important variables affecting the development of self-regulation in preschoolers. This finding can be used as basic data for parent education content to help preschoolers grow healthier and happier and as basic data for a program to improve parent-child attachment.

• Child Health Nursing Research
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• v.25 no.4
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• pp.388-397
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• 2019

Purpose: This study aimed to identify the degree of accident prevention behavior, self-esteem, self-regulation ability, and social support among middle-school students, and investigate factors influencing their practice of accident prevention behaviors. Methods: The participants were 174 students from two middle schools located in J city. Data were collected from December 28, 2017 to February 9, 2018 using self-reported questionnaires. Results: The mean score were $3.08{\pm}0.37$ of 4 for practice of accident prevention behaviors, $3.07{\pm}0.57$ of 4 for self-esteem, $3.69{\pm}0.48$ of 5 for self-regulation ability, and $3.38{\m}0.75$ of 5 for social support. Positive correlations were found among self-regulation ability, self-esteem, social support, and practice of accident prevention behaviors. The factors influencing the practice of accident prevention behaviors were personality (being 'haste') (${\beta}=-.20$, p=.003), self-regulation ability (${\beta}=.48$, p<.001), and social support (${\beta}=.23$, p<.001). These factors explained 39.0% of the variance in practice of accident prevention behaviors. Conclusion: It was found that the middle-school students engaged in prevention behavior to an extent that was insufficient to prevent accidents. Therefore, it is necessary to develop intervention strategies to improve the practice of accident prevention behavior among middle-school students, considering self-regulation ability, social support, and personality, which affect the practice of accident prevention behaviors.

• Journal of Korean society of Dental Hygiene
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• v.24 no.2
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• pp.187-195
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• 2024

Objectives: This study aimed to explore ways to improve the level of positive psychological capital of dental hygiene students. After comparing the levels of positive psychological capital, social support, and emotional regulation ability of dental hygiene students and identifying correlations, the sub-factors of social support and emotional regulation ability that affect positive psychological capital were identified. Methods: A survey of 70 questions was conducted targeting 310 dental hygiene students in Gyeonggi-do and Chungcheong-do. The results were subjected to exploratory factor analysis, frequency analysis, t-test, one-way ANOVA, correlation analysis, and multiple regression analysis using the PASW statistics 18.0 program. Results: The level of positive psychological capital was high when students had high grades and perceived positive relationships with professors and peers (p<0.001). Factors highly correlated with positive psychological capital include 'self-emotional regulation ability' among 'emotion regulation abilities' (r=0.665, p<0.001), and 'emotional support related to daily life' recognized 'social support' (r=0.635, p<0.001), followed by 'social support' (r=0.602, p<0.001). Factors affecting positive psychological capital include 'self-emotion recognized ability' (β=0.377, p<0.001), 'quality of professor relationship' (β=0.201, p<0.001), and 'emotion control ability'. Among 'social support', 'emotional support related to daily life' (β=0.201, p=0.003) and 'grades' (β=0.159, p<0.001), and among 'social support', 'social-related support' (β=0.149, p=0.016), followed by 'grade' (β=0.076, p=0.043) were identified. Conclusions: To improve the positive psychological capital of dental hygiene students, efforts should be made to improve self-emotion regulation ability, professor relationships, emotional support related to daily life, and social support.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.30 no.2
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• pp.287-304
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• 2020

There have been a number of legal & policy studies on the affecting factors of big data utilization, but empirical research on the composition factors of personal information regulation or data combination, which acts as a constraint, has been hardly done due to the lack of relevant statistics. Therefore, this study empirically explores the priority of personal information regulation factors and data combination factors that influence big data utilization through Delphi Analysis. As a result of Delphi analysis, personal information regulation factors include in order of the introduction of pseudonymous information, evidence clarity of personal information de-identification, clarity of data combination regulation, clarity of personal information definition, ease of personal information consent, integration of personal information supervisory authority, consistency among personal information protection acts, adequacy punishment intensity in case of violation of law, and proper penalty level when comparing EU GDPR. Next, data combination factors were examined in order of de-identification of data combination, standardization of combined data, responsibility of data combination, type of data combination institute, data combination experience, and technical value of data combination. These findings provide implications for which policy tasks should be prioritized when designing personal information regulations and data combination policies to utilize big data.

• Journal of the Korean Home Economics Association
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• v.42 no.3
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• pp.65-77
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• 2004

This study investigated emotional regulation, motive for emotional regulation and behavior problems of children. 64 boys and 58 girls in fourth grade and their mothers were selected for the subject. The children were interviewed about eight interpersonal conflict situations, while their mothers completed the CBCL(Child Behavior Check List). Major findings were as follows: emotional regulation, motive for emotional regulation and behavior problems differed according to the children's gender. Girls used more appropriate display rules for managing negative emotions, and more often, prosocial motives than boys. While girls displayed greater immature behavior, boys displayed more hyperactive and aggressive behavior. Negative emotional regulation was the most predictable variable for boy's behavior problems. Positive emotional regulation and prosocial motives were significant variables predicting girl's behavior problems. These findings implicate that emotional regulation and motive for emotional regulation are important factors in preventing behavior problems of school-age children.

• Journal of the Korea Convergence Society
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• v.12 no.9
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• pp.65-71
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• 2021

The purpose of this study is to investigate the factors that affect stress, emotional regulation, and adjustment to college life of health college students. The survey was conducted from June 21 to 30, 2021 for 190 health students in G and J area. The data were analyzed by frequency analysis, reliability analysis, simple correlation analysis, and multiple regression analysis. The results showed that positive perception had positive correlation with negative perception(r=-.286,p<.01), emotional regulation (r=.296,p<.01), and university life adjustment(r=.520,p<.01). Negative perception was correlated with emotional regulation(r=-.619,p<.01), university life adjustment (r=-.428,p<.01) and negative(-). Emotional regulation had a positive correlation with university life adjustment(r=.341,p<.01). Positive perception, negative perception, and emotional regulation, which are sub-factors of perceived stress, were the factors affecting the adjustment to university life, and the explanatory power was 84%. Therefore, it is necessary to develop a program that can improve the adjustment of college students in health.

• Korean Journal of Human Ecology
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• v.14 no.5
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• pp.761-770
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• 2005

This study focused on the relationship between young children's aggression and associated relative factors, so that we set young children's temperament, young children's self-regulation ability, mother's parenting efficacy, and mother's parenting behavior as associated relative factors. Therefore, we researched how these associated relative factors could affect young children's aggression. Subjects were 350 young children and their mothers who were attending nine kindergarten in I-city and J-city, Jeonlabuk-do. Statistics and methods used for data analysis were Cronbach's alpha, Pearson's correlation and Multiple Regression. Result's are as followings: First, as we researched into the correlation between young children's aggression and associated relative factors, we found that there were significant correlation in young children's temperament and mother's parenting efficacy, mother's indulgent and permissive parenting behavior, and controlled parenting behavior. Second, as we researched into the efficacy between young children's aggression and associated relative factors, we found that young children's aggression was directly affected by young children's active character that is one of young children's temperaments, young children's self-regulation ability, mother's active involvement in parenting behavior, mother's indulgent and permissive parenting behavior, and mother's controlled parenting behavior. That is, young children's aggression was 22% affected by these associated relative factors.

• Journal of the Korea Safety Management & Science
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• v.9 no.1
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• pp.77-84
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• 2007

This study was planned to investigate what the main factor of the regulation compliance of inspection on harmful machine, instrument and equipment by industrial safety and health act is. This study subject was composed of three groups as employers, employees of manufacturing and using the harmful machine and safety inspectors. Manufacturing workplace were 236 places, using workplace were 201 places and the safety inspectors were 100 people. The study subject was sampled by stratified random sampling considering the type of harmful Machine. Data for analysis is collected from each sample using interview with structured questionnaires. Compliance is measured by 2, 3, and 4 point scale composed by 8 sub items such as general perception, understanding, clearness, necessity, relevancy, implementation, penalty, and general compliance of the regulation. The level of 8 items of employer's compliance are not differentiated among three groups. The determining factors for inspection observance of the workplace using the harmful Machine were understanding, penalty and cognized compliance. The determining factors for inspection observance of the workplace manufacturing the harmful Machine were understanding and object conformity. These results show that the strategy to adapt the regulated group to inspection regulation will be the elevation of understanding for regulation first of all.