• Title/Summary/Keyword: Regulation Development

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Case Study on Technology and Regulation Improvement of Subway Maintenance Monitoring (지하철 유지관리 계측의 기술 및 제도 개선방안 연구)

  • 우종태;김홍석
    • Proceedings of the Korean Geotechical Society Conference
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    • 2000.03b
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    • pp.303-308
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    • 2000
  • By means of analyzing of monitoring technology and monitoring regulation based on maintenance monitoring system installed in subway tunnel section, it needs monitoring system, development of operating program, monitoring analyzing system and development of analysis method, establishment of maintenance monitoring standard specification, and performance of responsible monitoring supervision for applying to subway monitoring maintenance effectively in future. It requires specialized monitoring and legislation of monitoring subcontract, improvement of monitoring work contract method, establishment the standard payment of monitoring, and effective calibration and correction of monitoring system in the plan of improving monitoring regulation.

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Functional Enhancers As Master Regulators of Tissue-Specific Gene Regulation and Cancer Development

  • Ko, Je Yeong;Oh, Sumin;Yoo, Kyung Hyun
    • Molecules and Cells
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    • v.40 no.3
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    • pp.169-177
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    • 2017
  • Tissue-specific transcription is critical for normal development, and abnormalities causing undesirable gene expression may lead to diseases such as cancer. Such highly organized transcription is controlled by enhancers with specific DNA sequences recognized by transcription factors. Enhancers are associated with chromatin modifications that are distinct epigenetic features in a tissue-specific manner. Recently, super-enhancers comprising enhancer clusters co-occupied by lineage-specific factors have been identified in diverse cell types such as adipocytes, hair follicle stem cells, and mammary epithelial cells. In addition, noncoding RNAs, named eRNAs, are synthesized at super-enhancer regions before their target genes are transcribed. Many functional studies revealed that super-enhancers and eRNAs are essential for the regulation of tissue-specific gene expression. In this review, we summarize recent findings concerning enhancer function in tissue-specific gene regulation and cancer development.

System Dynamics Modeling for FDA Regulation Effect of Pharmaceutical Industry (제약산업에서 FDA규제 영향에 관한 시스템 다이내믹스 모델링: FDA규제가 R&D비용에 미치는 영향을 중심으로)

  • Ko, Seong-Pil;Choi, Jeong-Hwan;Nam, Dong-Wok;Lee, Jeong-Dong
    • Korean System Dynamics Review
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    • v.13 no.4
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    • pp.57-80
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    • 2012
  • This research studies effect of FDA regulations in pharmaceutical industry on new drug development. System dynamics is implemented to demonstrate dynamic relationship between FDA regulations and R&D costs, firm's profits, sales. This research is focused on clinical trials of new medical entity process 50~60% portion of total development cost. Simulation results say that firm's profit is more sensitive to increasing the regulation than alleviating the regulation and effect of regulation policy make different result depending on the intensity of regulation and policy direction. Our simulation model provides the instrumental means for the policy makers and strategic decision in pharmaceutical industry.

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The Relations Between Children's Emotion Regulation, Aggression and School Adjustment (남·여 아동의 정서조절 능력 및 공격성과 학교생활 적응간의 관계)

  • Park, Sung Yun;Kang, Ji Heun
    • Korean Journal of Child Studies
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    • v.26 no.1
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    • pp.1-14
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    • 2005
  • The present study aims to examine the relations between emotion regulation, aggression and school adjustment of boys and girls. A total of 321 5th-6th grades students were selected for the study. The data was collected via questionnaires. As results, there were some significant differences between boys and girls in overt aggression and peer adjustment. It was also found that emotion regulation, aggression and school adjustment were significantly correlated. And school adjustment was influenced by emotion regulation as well as overt and relational aggressions. Finally, only for boys, the relations between children's emotion regulation and school adjustment were mediated by their aggression.

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Cosmetic Regulation in Main Countries and Its Development Strategy in Korea (주요 국가의 화장품규정과 비교한 우리나라의 화장품법령 개정방안)

  • Kim, Young-Chan;Hwang, Soon-Wook;Kim, Dae-Joong
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.1 s.49
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    • pp.1-11
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    • 2005
  • The changes of cosmetic industry regulation in the leading countries, such as E.C., America, Japan, initiated our research to suggest the direction of our cosmetics regulation. These countries are strengthening the post-monitoring system for the safety and cosmetic industry development. We propose the agenda for the development of the industry; the extension of cosmetics range, deregulation of the advertisement, implementation of the ingredient labelling, introduction of the product expiring date. Ultimately. it is necessary to introduce and extend current CGMP to enhance the company responsibility and to reinforce the post-monitoring.

The Relationship between Children's Gender, Age, Temperament, Mothers' Emotionality, and Emotional Development (유아의 성, 연령, 기질 및 어머니의 정서성과 유아의 정서 발달의 관계)

  • An, Ra-Ri;Kim, Hee-Jin
    • Journal of the Korean Home Economics Association
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    • v.45 no.2
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    • pp.133-145
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    • 2007
  • The purpose of this research was to identify the importance of emotional development in early childhood, in children ages three to five, by examining the relationship between the variables in the children such as gender, age, and temperament, as well as their mothers' emotionality, in relation to emotional development. The participants included a total of 72 children between three and five years of age. The major findings are as follow: First, there were significant differences in emotional expression and emotional recognition between the boys and the girls. Additionally, the emotional recognition of the children increased as age increased, and more positive strategies for emotional regulation were used with the increasing age of the children. Temperament characteristics did not have any relationship with emotional expression or emotional recognition, while the strategies for emotional regulation were related to the temperament characteristics. Second, the emotional expressivity of the mother was related to the emotional expression and recognition of the child, but wes not associated with strategies for emotional regulation. The emotional reactivity of the mother was related to a child's strategies for emotional regulation, but not to emotional expression or recognition. Third, emotional development of the children wes influenced by the individual child variables and emotionality of the mother.

Development of the Control System for Fast-Responding Frequency Regulation in Power Systems using Large-Scale Energy Storage Systems

  • Lim, Geon-Pyo;Park, Chan-Wook;Labios, Remund;Yoon, Yong-Beom
    • KEPCO Journal on Electric Power and Energy
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    • v.1 no.1
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    • pp.9-13
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    • 2015
  • Energy storage systems (ESS) can be used to provide frequency regulation services in a power system to replace traditional frequency regulation power plants. Battery ESS, in particular, can provide "fast-responding frequency regulation," wherein the facility can respond immediately and accurately to the frequency regulation signal sent by the system operator. This paper presents the development and the trial run results of a frequency regulation control system that uses large-scale ESS for use in a large power system. The control system was developed initially for the 4 MW ESS demonstration facility in Jocheon Jeju Island, and was further developed for use in the 28 MW ESS facility at the Seo-Anseong substation and the 24 MW ESS facility at the Shin-Yongin substation to provide frequency regulation services within mainland Korea. The ESS facility in Seo-Anseong substation responds to a sudden drop in frequency via governor-free control, while the ESS facility in Shin-Yongin responds via automatic generator control (AGC).

Effect of Family Functioning on Preschoolers' School Readiness: Mediating Effects of Mothers' Affective Parenting and Preschoolers' Self-regulation (가족기능성이 어머니의 온정적 양육행동과 유아의 자기조절 능력을 매개로 학교준비도에 미치는 영향)

  • Jung, Suji;Choi, Naya
    • Human Ecology Research
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    • v.58 no.1
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    • pp.1-12
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    • 2020
  • This study examined if the effect of family functioning on preschoolers' school readiness can be mediated by mothers' affective parenting and preschoolers' self-regulation in the year before children enter elementary school. This study analyzed the 7th year data of panel study of Korean children collected by the Korean Institute of Child Care and Education. Statistical analysis included 1,513 pairs of 6-year-old children and mothers. Descriptive statistics analysis, correlation analysis, structural equation modeling, and bootstrapping analysis were conducted using SPSS 22 and Amos 20. The primary findings were as follows. First, the sub-factors of preschoolers' school readiness composed of children's social and emotional development, approach to learning, cognitive development and general knowledge, and communication were positively correlated with family functioning, mothers' affective parenting, and preschoolers' self-regulation. Second, the result of structural equation modeling showed that the indirect paths from family functioning to preschoolers' school readiness through mothers' affective parenting and preschoolers' self-regulation were significant, while the direct path was insignificant. Third, bootstrapping analysis showed that mothers' affective parenting and preschoolers' self-regulation fully mediated the relationship between family functioning and preschoolers' self-regulation. The findings provide the grounds for families and parents with preschool aged children to implement effective support practices to maintain a functional family system that can promote preschoolers' school readiness.

Analysis of Preservice Elementary Teachers' Lesson Plans

  • Hong, Jung-Lim
    • Journal of The Korean Association For Science Education
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    • v.24 no.1
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    • pp.171-182
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    • 2004
  • The purpose of this study is to analyze lesson plans from third to sixth grades of science and to find out teaching strategies in respects of learning functions provided by preservice elementary teachers in education university. On the whole, to control students' learning process preservice teachers used more shared-regulation strategy than strong teacher-regulation one. Teaching activities for regulative learning function were most used in strategy of strong teacher-regulation, and in strategy of shared-regulation those for cognitive learning functions were most used. But teaching activities for affective learning functions were used a little considered in both teaching strategies. In introduction step of instruction, affective and regulative learning functions were more instructed by strong teacher-regulation strategy and cognitive learning functions were more instructed by shared-regulation strategy. The affective, cognitive, and regulative learning functions were largely planned by shared-regulation teaching strategy in development. The regulative learning functions were planned by strong teacher-regulation strategy than by shared-regulation strategy and affective learning functions were considered a little bit in consolidation. There was a tendency that strong teacherregulation strategy was increased in lessons for fifth and sixth grade.

State Regulation of Banking Business in the Context of Social and Digital Transformation of the Economy

  • Rushchyshyn, Nadiya;Kulinich, Oksana;Tvorydlo, Olha;Mikhailov, Alexander;Viunyk, Olha
    • International Journal of Computer Science & Network Security
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    • v.22 no.4
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    • pp.67-72
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    • 2022
  • The main purpose of the study is to analyze the main aspects of state regulation of the banking business in the context of social and digital transformation. One of the key elements of the functioning of the economy of any country are banks that ensure the redistribution of financial resources and stimulate economic growth. However, the banking sector, like other activities, is dynamic and depends on the pace of development and forms of technological progress that affect the forms and types of information and digital technologies, as well as the globalization and remoteness of banking services. Accordingly, the need for effective implementation of the latest technologies becomes relevant, which will not only help increase consumer satisfaction with the banking product, but also ensure the development of the country's financial sector. As a result of the study, trends in the development of state regulation of the banking sector in the digital economy were identified.