• Title/Summary/Keyword: Regional Effects

Search Result 1,732, Processing Time 0.034 seconds

Anti-atherogenic Effect of Isoflavone through Hypolipidemic, Anti-oxidative and Anti-inflammatory Actions in C57BL/6 Mice (C57BL/6 Mice에서 이소플라본의 지질강하, 항산화, 항염증효과를 통한 항동맥경화 효과)

  • Cho, Hye-Yeon;Yang, Jeong-Lye;Noh, Kyung-Hee;Kim, Jin-Ju;Kim, Young-Hwa;Huh, Kyung-Hye;Song, Young-Sun
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.36 no.3
    • /
    • pp.276-283
    • /
    • 2007
  • This study was carried out to investigate the effect of isoflavone on the atherogenic effect in C57BL/6 mice. C57BL/6 female mice, 5 weeks of age, were fed on chow diets for 2 weeks during adjustment period. Mice weighing approximately $17.9{\pm}0.9\;g$ were divided into 4 groups and were fed on the experimental diets containing isoflavone for 8 weeks. Experimental groups were control (atherogenic diet), IF-10 (atherogenic diet with isoflavone 10 mg/100 g diet), IF-40 (atherogenic diet with isoflavone 40 mg/100 g diet) and IF-100 (atherogenic diet with isoflavone 100 mg/100 g diet). Food efficiency ratio was not different among the experimental groups. Plasma triglyceride (TG) concentrations were lower after 4 weeks in isoflavone supplementation groups than in control group, whereas monocyte chemoattractant protein-1 and thiobarbituric acid reactive substances (TBARS) levels of plasma were significantly (p<0.05) decreased in the isoflavone supplementation groups in a dose dependent manner. Both hepatic TG and cholesterol levels were significantly lowered in IF-100 than control. Hepatic glutathione concentrations were higher in the IF-100 group than in the other groups. Hepatic antioxidant enzyme activities including glutathione-reductase, glutathione-peroxidase, catalase, and Mn-superoxide dismutase were significantly higher in the isoflavone supplemen-tation groups in a dose dependent manner. From the above results, it is concluded that isoflavone may reduce the risk of atherosclerosis via hypolipidemic, anti-oxidative and anti-inflammatory effects.

A Study on the Influence of Human Resource Management Practices of Venture Firms on Performance (벤처기업의 인적자원관리가 기업성과에 미치는 영향에 관한 연구)

  • Weon, Jong-Ha
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
    • /
    • v.2 no.3
    • /
    • pp.61-102
    • /
    • 2007
  • This study empirically analyzed how human resource management(HRM) practices affect the performance of venture firms using The results of the study are as follows: First of all, several HRM practices were found to affect organizational performance significantly. Specifically, ${(1)}$ recruitment and selection practices were negatively related to turnover, which seemed to mean that effective staffing including development of good recruitment pools and rigorous selection process lower turnover, and ${(2)}$ training and development, compensation, and labor-management relations were positively related to subjective performance of the firms, which implied that as the venture firms provide more opportunities of training and development to employees, provide compensation on the basis of performance, and develop cooperative labor-management relations, the subjective performance of the venture firms Increases. Secondly, negative interaction effects were found to exist between competitive strategies and HRM practices on organizational performance. Specifically, ${(1)}$ the interaction between differentiation strategy and compensation were significantly related to turnover, ${(2)}$ HRM planning and training and development interacted with differentiation strategy to significantly affect subjective organizational performance, and ${(3)}$ HRM planning, selection, training and development, compensation and communication practices interacted with technology innovation strategy to affect subjective organizational performance. So far, there have not been many studies which deal with HRM practices of venture firms in Korea. Thus, it is hoped that this study stimulate more research efforts on theory development and empirical studies on HRM practices of venture firms. Also, it is hoped that government conduct more policy studies and provide more resources in HRM area of the venture firms. Specifically, it is suggested that government take proactive steps to improve industrial skilled staff and technical researcher systems in order to alleviate the problems of workforce shortages in venture firms. And it IS also suggested that regional human resource development programs be introduced with the participation of the firms, local governments, and universities.

  • PDF

Prelectin Histochemistry for Effects of N-Nitrosodimethylamine on Glycoconjugates in the Rat Lingual Glands (N-Nitrosodimethylamine이 흰쥐 설선의 Glycoconjugates에 미치는 영향에 대한 Prelectin 조직화학)

  • 조운복;조기진
    • Journal of Life Science
    • /
    • v.8 no.5
    • /
    • pp.509-519
    • /
    • 1998
  • The effect of N-Nitrosodimethylamine(NDMA) on the glycoconjugates of rat lingual salivary gland was examined by prelectin histochemical methods. Sprague-Dawley rats weighing about 250-300g were divided into control and experimental groups. Each rat of experimental groups was administrated NDMA(17mg/kg) orally and sacrificed in 3, 6, 12, 24, 48, 72, 96 and 120 hours after NDMA administration. The regional differences and change of glycoco-njugates were elucidated by prelectin histochemical methods, such as periodic acid Schiff's(PAS) reaction, alcian blue (AB) pH 2.5, AB pH 0.4, AB pH 2.5-PAS, aldehyde fuchsin(AF) pH 1.7-AB pH 2.5 and high iron diamine(HID)-AB pH 2.5 staining. The major morphological changes in the von Ebner’s gland of NDMA administrated groups were withering and des-truction of serous acini, diminution and disappearance of cytoplasmic granules and vacuolation in cytoplasm of serous cells, and mucinous changes of duct epithelial cells. These changes were noted in NDMA administrated groups for 12 to 72 hours. In the lingual mucous gland of NDMA administrated groups, the major morphological changes were enlargement, fusion and destruction of mucous acini, loss of cytoplasmic granules and vacuolated generation in cytop-lasm of mucous cells, and mucinous change of duct epithelial cells. These changes were severe in NDMA administra-ted groups for 12 to 72 hours. In NDMA administrated groups of lingual von Ebner's gland for 12 and 72 hours, the neutral glycoconjugates be-come diminished remarkably compared to the control group. The decreased amount of neutral glycoconjugates tended to be gradually recovered from 96 hours group. The acidic glycoconjugates which were not detected in control group were found in a few serous cells of these gland of NDMA administrated groups for 6 to 48 hours and 120 ho-urs. The remarkable decrease of neutral and acidic glycoconjugates was observed in the lingual mucous glands 3, 24 and 48 hours after NDMA administration, and the striking decrease of acidic glycoconjugates was found in 72 hours groups. Among acidic glycoconjugates, sulfated glycoconjugates tended to decrease in NDMA administrated groups for 72 hours, while sialic glycoconjugates were increased in NDMA administrated groups for 3, 12 and 48 hours.

  • PDF

Seismic Stratigraphy and Evolutionary History of Submarine Canyon in the Northwestern Part of the Ulleung Basin, East Sea (동해 울릉분지 북서해역에 분포하는 해저협곡의 탄성파 층서와 발달사)

  • Kim, Ji Hyun;Kang, Nyeon Keon;Yi, Bo Yeon;Park, Yong Joon;Yoo, Dong Geun
    • Geophysics and Geophysical Exploration
    • /
    • v.20 no.3
    • /
    • pp.146-162
    • /
    • 2017
  • Multibeam and seismic data in the northwestern part of the Ulleung Basin were analyzed to study stratigraphy and evolutionary history of submarine canyon. A detailed analysis reveals that the sedimentary sequences in this area consist of four stratigraphic units separated by erosional unconformities. On the continental slope, these units are dominated by well-stratified facies with some slope failures, whereas these units show well-stratified and chaotic facies toward the basin floor. Generally, the sediment thickness is relatively thin on the slope, whereas thick sediment accumulation occurs on the base of slope and basin floor. Based on seismic characteristics and distribution, the deposition of each units are well correlated with the evolutionary history of the submarine canyon. Unit 1 directly overlying the acoustic basement has thin sediment layer on the slope, whereas its thickness gradually increase toward the basin floor. Compared to other units, Unit 2 is relatively thick accumulations on the slope and contains some slope failures related to faults systems. The mass transport sediments due to slope failures, mainly deposited on the base of slope as a submarine fan. The width and depth of submarine canyon increase due to dominant of the erosional process rather than the sediment deposition. Unit 3 is thin accumulation on the slope around the submarine canyon. Toward the basin floor, its thickness gradually increases. Unit 4 is characterized by thin layers including slides and slumps on the slope, whereas it formed thick accumulations at the base of slope as a submarine fan. The increase in the width and depth of submarine canyon results from the dominant of the erosional process and slope failures around the submarine canyon. Consequently, the formation of sedimentary units combined with the development of submarine canyon in this area is largely controlled by the amounts of sediment supply originated from slope failures, regional tectonic effects and sea-level fluctuations.

Habitat Distribution Change Prediction of Asiatic Black Bears (Ursus thibetanus) Using Maxent Modeling Approach (Maxent 모델을 이용한 반달가슴곰의 서식지 분포변화 예측)

  • Kim, Tae-Geun;Yang, DooHa;Cho, YoungHo;Song, Kyo-Hong;Oh, Jang-Geun
    • Korean Journal of Ecology and Environment
    • /
    • v.49 no.3
    • /
    • pp.197-207
    • /
    • 2016
  • This study aims at providing basic data to objectively evaluate the areas suitable for reintroduction of the species of Asiatic black bear (Ursus thibetanus) in order to effectively preserve the Asiatic black bears in the Korean protection areas including national parks, and for the species restoration success. To this end, this study predicted the potential habitats in East Asia, Southeast Asia and India, where there are the records of Asiatic black bears' appearances using the Maxent model and environmental variables related with climate, topography, road and land use. In addition, this study evaluated the effects of the relevant climate and environmental variables. This study also analyzed inhabitation range area suitable for Asiatic black and geographic change according to future climate change. As for the judgment accuracy of the Maxent model widely utilized for habitat distribution research of wildlife for preservation, AUC value was calculated as 0.893 (sd=0.121). This was useful in predicting Asiatic black bears' potential habitat and evaluate the habitat change characteristics according to future climate change. Compare to the distribution map of Asiatic black bears evaluated by IUCN, Habitat suitability by the Maxent model were regionally diverse in extant areas and low in the extinct areas from IUCN map. This can be the result reflecting the regional difference in the environmental conditions where Asiatic black bears inhabit. As for the environment affecting the potential habitat distribution of Asiatic black bears, inhabitation rate was the highest, according to land coverage type, compared to climate, topography and artificial factors like distance from road. Especially, the area of deciduous broadleaf forest was predicted to be preferred, in comparison with other land coverage types. Annual mean precipitation and the precipitation during the driest period were projected to affect more than temperature's annual range, and the inhabitation possibility was higher, as distance was farther from road. The reason is that Asiatic black bears are conjectured to prefer more stable area without human's intervention, as well as prey resource. The inhabitation range was predicted to be expanded gradually to the southern part of India, China's southeast coast and adjacent inland area, and Vietnam, Laos and Malaysia in the eastern coastal areas of Southeast Asia. The following areas are forecast to be the core areas, where Asiatic black bears can inhabit in the Asian region: Jeonnam, Jeonbuk and Gangwon areas in South Korea, Kyushu, Chugoku, Shikoku, Chubu, Kanto and Tohoku's border area in Japan, and Jiangxi, Zhejiang and Fujian border area in China. This study is expected to be used as basic data for the preservation and efficient management of Asiatic black bear's habitat, artificially introduced individual bear's release area selection, and the management of collision zones with humans.

The Impact on the Business Effectiveness of the Educational Satisfaction in Elderly Employment Program: The Mediating Effect of Job Satisfaction (노인일자리 사업의 교육 만족도가 사업효과성에 미치는 영향 : 일자리 만족도의 매개효과)

  • Shin, Gye Soo;Kwon, Seung Sug
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
    • /
    • v.10 no.5
    • /
    • pp.105-115
    • /
    • 2015
  • This study examined what effect the educational satisfaction level in the grey job project had on the business effectiveness and verified the effect the participant education satisfaction level had on the project business effectiveness ultimately by influencing the job satisfaction. This study utilized the source data of the senior job project old participant status survey of the Korea senior manpower development center which was conducted in 2013, and the non-proportional stratification sample extracting method was used which considered the project type, regional size, and cities/provinces. Sejong City was excluded from the survey target and the survey targeted 2,005 persons except for non-response or response-irrelevant persons concerning this study question. The collected material was analyzed by using SPSS WIN 21.0 program. The frequency and percentage were calculated to apprehend the general characteristic of the study target. Also, the regression analysis was conducted to examine the effect the educational satisfaction level had on the business effectiveness of the senior job project, and the hierarchical regression analysis was conducted in order to examine the mediated effect of the job satisfaction level in the effect the educational satisfaction level had on the business effectiveness of the senior job project. The main result of this study is as follows. First, among the effects the educational satisfaction level had on the business effectiveness, both interest level of educational contents and the job utilization of education had a significant effect on the psychological effect, and the interest level of the educational contents had a significant level on the physical/social effect, and the job utilization of education had a significant effect on the economic effect. Second, in the effect the educational satisfaction level had on the business effectiveness, the job satisfaction level was confirmed the job satisfaction level had a partial mediated effect in the effect the educational satisfaction level had on the psychological/physical/social effect. The job satisfaction level was confirmed the job satisfaction level had a complete mediated effect in the effect the educational satisfaction level had on the economic effect. Also, The job satisfaction level was confirmed the job satisfaction level had a partial mediated effect in the effect the educational satisfaction level had on the business effectiveness. Consequently, the educational contents according with the demand of job participants will have to be developed and the exclusive manpower must be arranged to conduct the education effectively. Also, making participants feel a pride on the job fully will largely contribute to raising the business effectiveness because the job satisfaction level has a positive effect on the business effectiveness.

  • PDF

An Empirical Study on Technological Innovation Management Factors of SMEs (중소기업의 기술혁신 관리요소에 관한 실증연구)

  • Im, Chae-Hyon;Shin, Jin-Kyo
    • Journal of Technology Innovation
    • /
    • v.20 no.2
    • /
    • pp.75-107
    • /
    • 2012
  • Previous researches on technological innovation have several limitations such as lack of general mechanism for technological innovation(inputs, throughputs and outputs of technological innovation), large company oriented studies, and ignoring importance of technology management capabilities. So, this study suggested a new model using resource-based theory and system theory, and empirically applied that to SMEs. Structural equation model analysis by using 223 SMEs in Daegu region provided a support for most of hypotheses. Research results showed that all of factors on technological innovation were significantly and positively related with each other: inputs(R&D leadership, innovation strategy, R&D investment, R&D human resource management, external network), throughputs(portfolio management, project management, technology commercialization) and output(technological innovation). In case of technological innovation inputs, R&D leadership influenced on innovation strategy positively and significantly. And R&D leadership and innovation strategy had positive and significant effects on R&D investment, R&D human resource management and external network. R&D human resource management and external network exerted positive and significant influences on technological innovation throughputs such as portfolio management and project management. But R&D investment did not significant impacts on technological innovation throughputs. Among technological innovation throughputs, both portfolio management and project management had positive and significant effect on technology commercialization. In addition, technology commercialization acted positively and significantly technological innovation output. This study suggests necessary of efforts to implement innovation strategy and manage R&D human resource effectively based on CEO's innovativeness and entrepreneurship. Also, if SMEs want to develop technology and commercialize it, they have to cooperate with external technology resources and informations. Research results revealed that proper level of R&D investment, internal and external communication, information sharing, and learning and cooperative culture were very important for improvement of technological innovation performance in SMEs. Especially, this research suggested that if SMEs manage technological innovation process effectively based on resource-based and system approaches, then they can overcome their resource limitations and gain high technological innovation performance. Also, useful policy support for technological innovation of central or regional government by this research model is important factor for SMEs' technological innovation performance.

  • PDF

Temporal and Spatial Variation of Polychaete Community in Kwangyang Bay, Southern Coast of Korea (광양만 다모류군집의 시.공간적 변화)

  • 신현출;고철환
    • 한국해양학회지
    • /
    • v.25 no.4
    • /
    • pp.205-216
    • /
    • 1990
  • This study was carried out to investigate the composition and the distribution of the polychaete community in Kwangyang Bay during 1987-1988, and to deduce causal factors of temporal changes in community by the comparison with the results of 1982 (Choi, 1984). In the present study, the Polychaetes comprised a total of 79 species, and had a mean density of 520 ind. $.$m/SUP -2/. They showed high abundance and species diversity in the main tidal channel and the north channel of Myodo. The most abundant polychaete was Lumbrineris longifolia (28.2%), and followed by Nephtys polybranchia (16.3%) and Stermaspis scutata (8.3%). Comparing the polychaete community in summer of 1987 with that in summer of 1982, Lagis bocki and Chone teres, the most dominant species in 1982, disappeared in 1987, while Lumbrineris longifolia, Nephtys polybranchia, Terebellides horikoshii, and Sternapis scutata experienced above twice increases in densities. the community in the north channel was distinguished from those in other regions by the high abundance of L. bocki in 1982, but was similar to that of the main channel by the disappearance of L. bocki in 1987. The community in the western inner bay was similar to that of the main channel in 1982, but became to be distinguished by the disappearance of l. longifolia and the high densities of S. scutata and Tharyx sp. in 1987. The temporal change in species composition and regional difference might be induced by the combined effects in the changes of hydrologic and sedimentary environments owing to the reclamation on the delta of Seomjing River and the dredging of the north chnnel.L.bocki in the north chnnel vanished after the habitat disturbance by the reclamation and dredging.S.scutata and Tharyxsp.dominated in the western inner bay because of the accumulationfo fine sediments through weakenend durrent flow by the obstruction of a new bank constructed on the delta.

  • PDF

Effect of Dietary Silkworm Droppings on Chemical Composition of Pork Loin (잠분(蠶糞) 급여가 돈육 등심의 화학적 조성에 미치는 영향)

  • Lee, J.I.;Lee, J.D.;Ha, Y.J.;Jung, J,D.;Lee, J.W.;Lee, J.R.;Kwack, S.J.;Kim, D.H.;Do, C. H.
    • Journal of Animal Science and Technology
    • /
    • v.46 no.6
    • /
    • pp.1013-1022
    • /
    • 2004
  • This study investigated the effects of silkworm droppings(SWD) added diet feeding on chemical composition of pork loin meat. Pigs were divided into 7 treatment groups(10 pigs/group) and subjected to one of seven treatment diets(O, 1 0/0, 2 0/0, 3% SWD for 4 weeks, 1 0/0, 2 0/0, 3% SWD for 8 weeks, SWD diets; total fed diets) before slaughter. Pork loin were collected from the animals(1l0 kg body weight) slaughtered at a commercial slaughter house. Pork loin meat were aerobic packaged and then stored at$4^{\circ}C$ for 2, 5, 8, or 12 days. Samples were analyzed for TBARS, sensory evaluation, myoglobin content, fatty acid composition, amino acid and mineral content. TBARS value was not significantly different between the control and SWD treatment groups. Myoglobin content of SWD fed group pork was significantly increased than that of control group(P<0.05). Marbling score and acceptability were increased in SWD fed pork compared to those in control pork. Na, Mg, Ca, Mn and Fe content of SWD fed group pork was significantly decreased than those of control group(P<0.05). P content was significantly increased than that of control group(P< 0.05). In the change of amino acid composition, the contents of aspartic acid, serine and tyrosine were decreased by dietary SWD-supplementation, whereas the SWD-supplementation resulted in the higher glutamic acid, alanine and isoleucine. As dietary SWD was increased in feed, the content of oleic acid was significantly increased, but stearic acid was significantly decreased(P<0.05).

Transfer Factor of Heavy Metals from Agricultural Soil to Agricultural Products (농작물 재배지 토양 내 비소, 납 및 카드뮴의 농산물로의 전이계수 산출)

  • Kim, Ji-Young;Lee, Ji-Ho;Kunhikrishnan, Anitha;Kang, Dae-Won;Kim, Min-Ji;Yoo, Ji-Hyock;Kim, Doo Ho;Lee, Young-Ja;Kim, Won Il
    • Korean Journal of Environmental Agriculture
    • /
    • v.31 no.4
    • /
    • pp.300-307
    • /
    • 2012
  • BACKGROUND: The Transfer Factor (TF) of heavy metals from soil to plant is important, because TF is an indicator of heavy metal in soils and a factor that quantifies bioavailability of heavy metals to agricultural products. This study was conducted to investigate the transfer ability of Arsenic (As), Cadmium (Cd), and Lead (Pb) from soil to agricultural products. METHODS AND RESULTS: We investigated heavy metals (As, Cd and Pb) concentrations in 9 agricultural products (rice, barely, corn, pulse, lettuce, pumpkin, apple, pear, tangerin) and soil. TF of agricultural products was evaluated based on total and HCl-extractable soil concentration of As, Cd, and Pb. Regression analysis was used to predict the relationship of total and HCl-extractable concentration with agricultural product contents of As, Cd, and Pb. The result showed that TF was investigated average 0.006~0.309 (As), 0.002~6.185 (Cd), 0.003~0.602 (Pb). The mean TF value was the highest as rice 0.309 in As, lettuce 6.185, pear 0.717, rice 0.308 in Cd, lettuce 0.602, pumpkin 0.536 in Pb which were dependent on the vegetable species and cereal is showed higher than fruit-vegetables in As. CONCLUSION(S): Soil HCl-extractable concentration of As, Cd, and Pb had the larger effects on thier contents in agricultural products than total soil concentrations. We suggests that TF are served as influential factor on the prediction of uptake. Further study for uptake and accumulation mechanism of toxic metals by agricultural products will be required to assess the human health risk and need TF of more agricultural products.