• Korean Journal of Pharmacognosy
• /
• v.46 no.1
• /
• pp.65-71
• /
• 2015

Although it has recently been reported that Acanthopanax senticosus has a protective effect against the development of metabolic disorders such as diabetes and hyperlipidemia, its underlying molecular mechanisms have remained to be elucidated. In this study, we observed that treatment of an extract of A. senticosus (ASE) reduced body weight and adiposity and improved glucose tolerance in high-fat diet (HFD)-induced obese mice. HFD-induced weight gain in white adipose tissues and liver was also significantly reduced in ASE-treated HFD-fed mice, which was found to be contributed by suppression of mRNA expression of genes involved in fatty-acid uptake and fat synthesis in white adipose tissue. ASE treatment also attenuated M1 macrophage activation, increased regulatory T ($T_{reg}$) cell population, and modulated leptin/adiponectin profile that might alleviate chronic inflammation to protect against HFD-induced insulin resistance. Our findings suggest a therapeutic potential of ASE for prevention and treatment of type 2 diabetes without adverse effects such as weight gain and dyslipidemia.

• Journal of Power System Engineering
• /
• v.22 no.1
• /
• pp.72-78
• /
• 2018

With growing concerns over air pollutions attributed to shipping activities, the international maritime organization has enacted a series of stringent regulations. In particular, MARPOL Annex IV Reg. 16 requires sulfur contents from exhaust gases of marine engines to be progressively reduced. To comply with this regulation, three feasible options have been introduced: using LNG as a marine fuel, using heavy fuel oil with the scrubber system, and using the marine gas oil (a type of low sulfur fuel oil). For the objectives of this paper, the holistic environmental impacts pertinent to these options were investigated and compared in ways that the flows of energy and emission were tracked and quantified through the life cycle of the ship. Research findings obtained from a case study with a large bulk carrier showed that the use of the scrubber system to purify heavy fuel oil would produce relatively fewer amounts of emissions attributing to global warming than other two options. On the other than, the use of LNG would be the way to operate the ship in a cleaner way in terms of reducing the acidification, eutrophication, and photochemical effects. Throughout the analysis, the excellence of life cycle assessment was proven to shift the environmental impact of marine systems from the short-term view to the long-term one.

• JSTS:Journal of Semiconductor Technology and Science
• /
• v.16 no.4
• /
• pp.528-533
• /
• 2016

A low voltage high PSRR CMOS Bandgap circuit capable of generating a stable voltage of less than 1 V (0.8 V and 0.5 V) robust to Process, Voltage and Temperature (PVT) variations is proposed. The high PSRR of the circuit is guaranteed by a low-voltage current mode regulator at the central aspect of the bandgap circuitry, which isolates the bandgap voltage from power supply variations and noise. The isolating current mirrors create an internal regulated voltage $V_{reg}$ for the BG core and Op-Amp rather than the VDD. These current mirrors reduce the impact of supply voltage variations. The proposed circuit is implemented in a $0.35{\mu}m$ CMOS technology. The BGR circuit occupies $0.024mm^2$ of the die area and consumes $200{\mu}W$ from a 5 V supply voltage at room temperature. Experimental results demonstrate that the PSRR of the voltage reference achieved -118 dB at frequencies up to 1 kHz and -55 dB at 1 MHz without additional circuits for the curvature compensation. A temperature coefficient of $60 ppm/^{\circ}C$ is obtained in the range of -40 to $120^{\circ}C$.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2010.05a
• /
• pp.1580-1584
• /
• 2010

지역기후모델 RegCM3 이용하여 역학적 상세화 이중둥지격자체계를 구축하고 관측, ECHO-G/S의 20C3M 및 SRES A2 시나리오를 이용하여 동아시아(60km 분해능)와 한반도(20km 분해능)에 대한 현재 및 미래(1971-2100, 130년)의 기후변화 시나리오 자료를 생산하였다. 미래 동아시아와 한반도지역은 기온상승에 의해 대기 중 수증기 함유량 증가와 여름 몬순의 강화로 전 계절에 걸쳐 강수량이 증가하고 토양수분, 증발산도 증가할 것으로 전망되었다. 상세화된 일(daily)강수량 자료를 일반극치(general extreme value, GEV)분석을 활용하여 20세기 동안 한반도의 일최대강수량의 공간 분포를 분석하고 미래 강수의 일최대강수량 변화를 전망하였다. 20세기 (1971-2000)에는 남해안과 경기 내륙지방에서 일최대강수량의 빈도와 평균값이 나타났다. 21세기에는 일최대강수량의 평균은 현재보다 약 10 $mmday^{-1}$, 20년 빈도 강수량은 60 $mmday^{-1}$ 정도 증가할 것이고, 남해안과 서해안과 충청내륙일부지방, $39^{\circ}N$ 이북에서 뚜렷이 나타날 것으로 전망되었다.

• Journal of Families and Better Life
• /
• v.34 no.5
• /
• pp.151-166
• /
• 2016

This study examined frequency of contact between parents and their non-coresident, never-married daughters and sons compared to children in other marital statuses. Despite an increasing number of never married adults, little is known about the extent to which they may be willing to remain connected to and exchange support with their parents. The data were drawn from first wave of the Korean Longitudinal Study of Ageing (KLoSA, 2006). For analyses, respondents who had at least one non-coresident child aged 40 or older were selected, resulting in the analytic sample of 2,755 parents with 7,741 children. Both sibling fixed effects regression models and regression models with robust standard errors were estimated using the xtreg and reg procedures in STATA. Findings revealed significant marital status by gender interaction effects on face-to-face contact. Never-married daughters were more likely to see their parents compared to their married, divorced, or widowed counterparts. Never-marred sons, on the other hand, reported slightly lower levels of in-person contact with their parents in comparison to married sons and lower levels of contact compared to divorced or widowed sons. More frequent contact via phone, mail, or email was reported in daughter-parent relationship compared to son-parent relationship, but no significant marital status by gender interactions were observed.

• Proceedings of the Korean Information Science Society Conference
• /
• 2005.07a
• /
• pp.853-855
• /
• 2005

본 논문은 Sequence Diagram을 이용한 안전등급 PLC(Safety-Grade Programmable Logic Controller) 운영 체제의 인터페이스 설계명세를 기술한다. 원자력 발전소에 사용하기 위한 안전 소프트웨어(Safety Software)의 규제 기준인 Reg. Guide는 IEEE Std 1016, IEEE Std 1016.1 의 설계명세서 작성 표준에 따라 작성하도록 요구하며, 이러한 규제기준과 기 표준을 안전등급 PLC를 위한 운영체제 소프트웨어의 설계명 세서도 만족해야 한다. 특히 운영 체제와 외부 장치들 사이의 인터페이스를 위해 실시간 특성의 표현에 장점을 갖는 Sequence Diagram을 적용함으로써 운영체제의 인터페이스에 대한 정확성, 완전성, 그리고 일관성을 향상시킬 수 있었다.

• Bulletin of the Korean Chemical Society
• /
• v.20 no.9
• /
• pp.1067-1072
• /
• 1999

Structures of unprotonated [(NH3)n+(n = 1-6)] and protonated [NH4+(NH3)n-1(n = 1-6)] ammonia cluster cations have been optimized with ab initio Hartree-Fock (HF) and second-order MФller-Plesset (MP2)/6-31+G ** levels and the harmonic vibrational frequencies have also been evaluated. In unprotonated cluster cations, NH3+ forms as a central core of the first ammonia solvation shell. In protonated cluster cations, NH4+ forms as a central core. In unprotonated dimer and trimer cations, there are two types of isomers (hydrogen-bonded and head-to-head interactions). In both cluster cations, the hydrogen-bonded isomers are more stable. In the hydrogen-bonded dimer cation, the proton transfer reaction takes place from (NH3-HN+H2) to (NH4+-NH2). But in the other unprotonated cluster cations, the proton transfer does not take place. In unprotonated pentamer and hexamer, a NH3+ core has both interactions in a complex. On the other hand, in unprotonated tetramer a core has only the hydrogen-bonded type combined with neutral ammonia molecules. With increasing cluster cation size, the bond lengths [R(NN)] between two nitrogen atoms and the distances [R(N ...H)] of the hydrogen-bond increase reg-ularly. In the calculated infra-red absorption bands for ammonia cluster cations, the characteristic peaks of the bridged NH vibration of the hydrogen-bonded clusters appear near 2500 cm-1 . With increasing size, the peaks shift from 2306 cm-1 to 2780 cm-1 .

• Journal of Climate Change Research
• /
• v.7 no.4
• /
• pp.407-419
• /
• 2016

The low flow is the necessary and important index to establish national water planning, however there are lots of uncertainty in the low flow estimation. Therefore, the objectives of this study are to assess the climate change uncertainty and the effects of hydrological models on low flow estimation. The 5 RCMs (HadGEM3-RA, RegCM4, MM5, WRF, and RSM), 5 statistical post-processing methods and 2 hydrological models were applied for evaluation. The study area were selected as Chungju dam and Soyang river dam basin, and the 30 days minimum flow is used for the low flow evaluation. The results of the uncertainty analysis showed that the hydrological model was the largest source of uncertainty about 41.5% in the low flow projection. The uncertainty of hydrological model is higher than the other steps (RCM, statistical post-processing). Also, VIC model is more sensitive for climate change compared to SWAT model. Therefore, the hydrological model should be thoroughly reviewed for the climate change impact assessment on low flow.

• Nuclear Engineering and Technology
• /
• v.51 no.7
• /
• pp.1791-1798
• /
• 2019

Instrumentation and Control (I&C) systems of nuclear power plants (NPPs) have been continuously digitalized. These systems have a critical role in the operation of nuclear facilities by functioning as the brain of NPPs. In recent years, as cyber security threats to NPP systems have increased, regulatory and policy-related organizations around the world, including the International Atomic Energy Agency (IAEA), Nuclear Regulatory Commission (NRC) and Korea Institute of Nuclear Nonproliferation and Control (KINAC), have emphasized the importance of nuclear cyber security by publishing cyber security guidelines and recommending cyber security requirements for NPP facilities. As described in NRC Regulatory Guide (Reg) 5.71 and KINAC RS015, challenge response authentication should be applied to the critical digital I&C system of NPPs to satisfy the cyber security requirements. There have been no cases in which the most robust response authentication technology like challenge response has been developed and applied to nuclear I&C systems. This paper presents a challenge response authentication mechanism for a Programmable Logic Controller (PLC) system used as a control system in the safety system of the Advanced Power Reactor (APR) 1400 NPP.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2018.05a
• /
• pp.168-168
• /
• 2018

최근 기후변화로 인하여 전 세계적으로 과거 강우사상에서 확인되지 않는 극치사상이 빈번하게 관측되고 있으며 이에 따른 피해도 증가하고 있다. 미래의 기상학적 변동성 및 기후변화 영향은 지구순환모형 (General Circulation Models, GCM)을 통해 구체화되며 가장 일반적인 기후변화 전망자료로서 활용된다. 그러나 산정된 기후변화 시나리오마다 서로 그 특성에 차이가 있으며 이러한 이유로 다양한 원인으로 인해 큰 변동성을 가지는 미래 극치강우를 하나의 시나리오로 분석하기에는 무리가 있다. 또한 다양한 시나리오를 통해 분석한 결과값이 상이하며 이러한 시나리오별 산정 결과의 차이는 사용자에게 혼란을 야기할 수 있어 이를 하나의 결과로 나타낼 필요성이 있으나 정량적인 대푯값을 얻기 위해 특정 시나리오를 선택하는 것은 신뢰성에 문제가 있다. 본 연구에서는 시나리오들을 정량적 지표에 의거하여 혼합된 하나의 시나리오로 표출하고자 하였다. CORDEX-RCMs 시나리오 중 HadGEM3-RA, RegCM, SNU_WRF 및 GRIMs를 입력 자료로 하여 다중모형앙상블(Multi-Model Ensemble, MME)을 통해 낙동강 유역의 극치강우에 대한 하나의 최적 기후변화 시나리오를 도출하고자 하였으며 계층적 베이지안 (Hierarchical Bayesian Model, HBM) 기법을 통하여 기후변화 시나리오에 내제된 불확실성에 대한 정량적인 해석을 수행하였다.