• Macromolecular Research
• /
• 제15권7호
• /
• pp.682-687
• /
• 2007

The equation of state developed herein is predicated on a hard-sphere reference with perturbations introduced via a potential function to account for electrostatic forces and for attraction between protein particles. During this process, the generalized Lennard-Jones (GLJ) pair potential function is employed. The GLJ pair potential function is employed to represent the protein-protein interaction in two-protein systems. Via the use of the relation between the equation of state and the chemical potential, the phase behavior in the aqueous two-protein system can be estimated. The partition coefficients can be obtained via these processes. The calculated values of the coefficients agree fairly well with the experimental data in the given pH and ionic strength range, with no additional adjustable model parameters.

• Journal of Radiation Protection and Research
• /
• 제41권3호
• /
• pp.211-215
• /
• 2016

Background: The moderated neutron calibration fields using $^{241}Am$-Be sources and a graphite moderator have been constructed at the Facility of Radiation Standard (FRS) in the Japan Atomic Energy Agency (JAEA). Materials and Methods: The neutron spectra of the fields were evaluated by the Monte-Carlo calculations and measurements using the Bonner Multi-sphere Spectrometer. Results and Discussion: The fields have continuous neutron spectra from several MeV to thermal neutron energy, with fluence-averaged energies of 0.84 MeV and 0.60 MeV. Reference values of fluence rates and ambient/personal dose equivalent rates were determined from neutron spectra by measurements. Conclusion: Currently, the fields are available for calibration or performance test of neutron measuring instruments.

• 조명전기설비학회논문지
• /
• 제15권1호
• /
• pp.1-6
• /
• 2001

조명업체에서 적분구를 이용한 광원의 전광선속을 측정하는데 기준광원으로 활용하기 위하여 신뢰성 높은 전광선속 표준전구를 개발하였다. 전광선속 표준전구는 공간세기분포가 균일하도록 되어 있으며, 사용시간 100[h]동안에 전광선속 변화율이 0.5% 이내로 양호한 안정도를 갖는다.

• Journal of Radiation Protection and Research
• /
• 제28권4호
• /
• pp.327-335
• /
• 2003

The commercially available neutron survey meter, the REM500, which uses a tissue equivalent proportional counter (TEPC) and the self-constructed TEPC were used to determine the microdosimetric quantities of several neutron calibration fields at Korea Atomic Energy Research Institute (KAERI). Microdosimetric spectra, absorbed dose, dose equivalent as well as quality factor were derived and compared with several neutron fields which were produced by using the shadow objects to make neutron scattered and being used as a kind of realistic neutron calibration fields at KAERI. The response of REM500 as a function of mean energy was evaluated with these neutron fields using the counts measured and the predetermined reference value. The response of the self-made TEPC and the REM500 was compared using one of the neutron calibration filelds of a $^{252}Cf$ source. The reference quantities of scattered neutron calibration fields were determined using a Bonner Sphere (BS). The value of frequency-mean lineal energy, dose-mean lineal energy and quality factor of two $^{252}Cf$ sources (unmoderated and $D_2O$ moderated) were determined to check the differences in the reference neutron fields between KAERI and Pacific Northwest National Laboratory (PNNL, USA) and the results were in good agreement within 1%. It means that there is no big difference in dosimetric quantifies of neutron calibration fields of two laboratories.

• 한국임상수의학회지
• /
• 제30권4호
• /
• pp.268-272
• /
• 2013

The purpose of this study was to assess the effects of reconstruction kernel, and slice thickness on the accuracy of spiral CT-based volume assessment over a range of object sizes typical of synthetic simulated tumor. Spiral CT scanning was performed at various reconstruction kernels (soft tissue, standard, bone), and slice thickness (1, 2, 3 mm) using a phantom made of gelatin and 10 synthetic simulated tumors of different sizes (diameter 3.0-12.0 mm). Three-dimensional volume assessments were obtained using an automated software tool. Results were compared with the reference volume by calculating the percentage error. Statistical analysis was performed using ANOVA and setting statistical significance at P < 0.05. In general, smaller slice thickness and larger sphere diameters produced more accurate volume assessment than larger slice thickness and smaller sphere diameter. The measured volumes were larger than the actual volumes by a common factor depending on slice thickness; in 100HU simulated tumors that had statistically significant, 1 mm slice thickness produced on average 27.41%, 2 mm slice thickness produced 45.61%, 3 mm slice thickness produced 93.36% overestimates of volume. However, there was no statistically significant difference in volume error for spiral CT scans taken with techniques where only reconstruction kernel was changed. These results supported that synthetic simulated tumor size, slice thickness were significant parameters in determining volume measurement errors. For an accurate volumetric measurement of an object, it is critical to select an appropriate slice thickness and to consider the size of an object.

• 대한방사선치료학회지
• /
• 제29권2호
• /
• pp.101-108
• /
• 2017

목 적: 양성자치료에 이용되는 양성자선은 종양 부위 앞에 있는 정상 조직에는 적은 선량을 주는 반면 암 조직 부위에서는 브래그 피크(Bragg peak)를 형성하며 최대 선량을 주고 바로 소멸하는 특징을 가지고 있으며 양성자치료의 장점을 극대화하기 위해서는 양성자의 도달 위치 검증이 매우 중요하다. 본 연구에서는 Off-line PET CT 방법을 이용하여 양성자 조사 후 양성자 궤적을 따라 생성된 11 C(반감기=20분), 150(반감기=2분), 13N (반감기=10분) 등의 핵자에서 방출되는 양전자의 분포를 측정하여 양성자의 Range와 Distal falloff 지점을 검증하게 되었다. 대상 및 방법: IEC 2001 Body 팬텀안에는 37 mm, 28 mm, 22 mm 구체를 삽입할 수 있게 구성되어 있으며 팬텀안에 물을 가득 채워 각 구체크기별로 CT image를 획득하였고 양성자의 Range와 Distal falloff 지점을 검증하기 위하여 양성자치료계획시스템으로 각 구체 크기 별로 37 mm 구체에서 46 mm, 28 mm에서 37 mm, 22 mm 구체에서 33 mm의 SOBP를 설정하였고, Scanning 방법으로 Gantry 0도의 Single beam으로 동일한 센터에서 양성자를 조사하였다. 조사된 팬텀은 PET-CT 장비를 이용하여 스캔하였고, PET-CT 영상획득방법은 1분씩 50개의 영상을 획득하여 팬톰 내의 구체를 포함하여 4개의 ROI를 설정한 후 10개씩 영상을 합산하여 재구성 하였다. 치료계획 시 수립한 구체크기에 따른 Dose profile과 비교하기 위하여 Depth에 따른 Activity profile로 나타냈다 결 과: 37 mm, 28 mm, 22 mm 구체에서 모두 Distal falloff position 에서 Dose profile과 같이 PET-CT의 Activity profile 역시 급격히 감소하는 양상을 나타냈다. 하지만 Range를 평가하는 구간인 SOBP구간에서는 Activity profile의 경우 Proximal 부분에서의 측정치가 Dose profile 양상과 다른 결과가 나왔으며, Distal falloff position을 구체 크기별로 양성자 치료계획과 PET-CT 측정치와의 차이를 비교해 본 결과 37 mm 구체에서는 Max dose의 50 % 지점에서 최대 1.4 mm, 28 mm 구체에서는 45 % 지점에서 최대 1.1 mm, 22 mm 구체에서의 차이는 40 % 지점에서 최대 1.2 mm로 모두 1.5 mm 미만의 차이를 보였다. 결 론: 양성자치료의 장점을 최대한 활용하기 위해서는 양성자빔의 Range를 검증하는 것이 매우 중요하다. 본 연구에서는 PET-CT 장비를 이용하여 양성자빔의 SOBP 와 Distal falloff 위치를 통해 양성자 Range를 확인하였고 그 결과 PET-CT 장비를 이용해 측정한 Activity 분포와 양성자 치료계획과의 Distal falloff position의 차이는 1.4 mm 내에서 일치함을 확인하였다. 이는 본원에서 양성자치료계획 시 적용하는 선량마진에 참고자료로 활용될 수 있을 것으로 사료된다.

• 한국지역지리학회지
• /
• 제3권1호
• /
• pp.13-34
• /
• 1997

도시세력권은 도시의 인구와 경제규모, 교육 문화 의료시설을 비롯한 제반 서비스기능의 정도 등에 따라 결정되는데, 통근권은 도시세력권을 결정하는 가장 좋은 지표에 속한다. 왜냐하면 통근권은 지역 주민들의 규칙적인 일상생활과 직접적으로 관계되며 매일의 유동량을 정확하게 표현해 주기 때문이다. 본 연구는 경남 서부지역의 중심지 세력권 변화와 이에 따른 주민 통근행태의 성격을 구명하는 것을 목적으로 한다. 진주시는 전국 차원에서 보면 지방 중소도시에 지나지 않지만 경남 서부지역에서는 절대적인 중심지 역할을 수행하고 있으며 매우 넓은 세력권을 갖는다. 본 연구에서는 경남 서부지역 중심지들의 세력권을 인구와 산업의 변화를 통하여 고찰하고, 주민들의 통근행태를 주택-인구센서스의 통근-통학자료와 진주시 의료기관의 환자 동계자료 및 초 중등학교 교사들의 통근자료를 통하여 분석한다. 특히 교사들의 통근율에 따른 진주 도시세력권은 진주시로부터의 거리조락성과 도시간의 세력권 경합관계에 따라 결정된다. 경남 서부지역 교사들의 역통근 행태는 학교가 입지한 지역사회의 입장에서는 부정적 영향이 보다 크게 작용하고 있는 것으로 확인된다. 따라서 농어촌의 소규모 중심지들에 대한 각종 서비스시설을 확충함으로써 지역간 균형개발을 도모하여야 할 것이다.

• 한국CDE학회논문집
• /
• 제13권6호
• /
• pp.403-411
• /
• 2008

The alignment of facial images is crucial for 2D face recognition. This is the same to facial meshes for 3D face recognition. Most of the 3D face recognition methods refer to 3D alignment but do not describe their approaches in details. In this paper, we focus on describing an automatic 3D alignment in viewpoint of quantitative analysis. This paper presents a framework of 3D face alignment and normalization based on feature points obtained by Active Shape Models (ASMs). The positions of eyes and mouth can give possibility of aligning the 3D face exactly in three-dimension space. The rotational transform on each axis is defined with respect to the reference position. In aligning process, the rotational transform converts an input 3D faces with large pose variations to the reference frontal view. The part of face is flopped from the aligned face using the sphere region centered at the nose tip of 3D face. The cropped face is shifted and brought into the frame with specified size for normalizing. Subsequently, the interpolation is carried to the face for sampling at equal interval and filling holes. The color interpolation is also carried at the same interval. The outputs are normalized 2D and 3D face which can be used for face recognition. Finally, we carry two sets of experiments to measure aligning errors and evaluate the performance of suggested process.

• International Journal of Fluid Machinery and Systems
• /
• 제8권4호
• /
• pp.264-273
• /
• 2015

This presentation describes an experimental approach for the detection of cavitation in hydraulic machines by use of ultrasonic signal analysis. Instead of using the high frequency pulses (typically 1MHz) only for transit time measurement different other signal characteristics are extracted from the individual signals and its correlation function with reference signals in order to gain knowledge of the water conditions. As the pulse repetition rate is high (typically 100Hz), statistical parameters can be extracted of the signals. The idea is to find patterns in the parameters by a classifier that can distinguish between the different water states. This classification scheme has been applied to different cavitation sections: a sphere in a water flow in circular tube at the HSLU in Lucerne, a NACA profile in a cavitation tunnel and two Francis model test turbines all at LMH in Lausanne. From the signal raw data several statistical parameters in the time and frequency domain as well as from the correlation function with reference signals have been determined. As classifiers two methods were used: neural feed forward networks and decision trees. For both classification methods realizations with lowest complexity as possible are of special interest. It is shown that two to three signal characteristics, two from the signal itself and one from the correlation function are in many cases sufficient for the detection capability. The final goal is to combine these results with operating point, vibration, acoustic emission and dynamic pressure information such that a distinction between dangerous and not dangerous cavitation is possible.

• 제어로봇시스템학회논문지
• /
• 제13권10호
• /
• pp.962-969
• /
• 2007

In this paper, an approach is developed for relative state estimation of satellite formation flying. To estimate relative states of two satellites, the Extended Kalman Filter Algorithm is adopted with the relative distance and speed between two satellites and attitude of satellite for measurements. Numerical simulations are conducted under two circumstances. The first one presents both chief and deputy satellites are orbiting a circular reference orbit around a perfectly spherical Earth model with no disturbing acceleration, in which the elementary relative orbital motion is taken into account. In reality, however, the Earth is not a perfect sphere, but rather an oblate spheroid, and both satellites are under the effect of $J_2$ geopotential disturbance, which causes the relative distance between two satellites to be on the gradual increase. A near-Earth orbit decays as a result of atmospheric drag. In order to remove the modeling error, the second scenario incorporates the effect of the $J_2$ geopotential force, and the atmospheric drag, and the eccentricity in satellite orbit are also considered.