• 대한지역사회영양학회지
• /
• 제6권1호
• /
• pp.51-68
• /
• 2001

This investigation studied the relationship between Body Mass Index(BMI) and dietary intake, levels of serum lipid, lipoprotein(a) and plasminogen activator inhibitor-1(PAI-1) of 28.449 Korean adults(16.937 men, 11.542 women) from 1995 to 1999. The dietary assessment was conducted using 24-hour dietary records and food frequency questionnaires. During this five year study, the BMI normal-weight group, as a percentage of the annual test population, decreased from 68.0% to 60.2%, while the BMI overweight and obese groups collectively increased from 25.0% to 29.7%. The levels of serum total cholesterol (TC), LDL-cholesterol(LDL-C), Triacylglycerol(TG) and PAI-1 increased as the values of BMI increased, while the levels of HDL-cholesterol(HDL-C) and lipoprotein(a)(men only) appeared to decrease as values of BMI increased. The levels of daily energy intake also increased as values of BMI increased in both men and women. The obese group had significantly higher levels of carbohydrate, protein, fat(men only), and cholesterol intake than those of the normal-weight, underweight, and overweight groups. In men, BMI positively correlated with the levels of macronutrients and cholesterol intake(p＜0.001), % energy of protein, fat, and alcohol intake(p＜0.001), and the levels of serum TC, LDL-C, TG and PAI-1(p＜0.001), while BMI negatively correlated with % energy of carbohydrate intake, and the levels of Lp(a) and HDL-C(p＜0.001). In women, BMI negatively correlated with level of cholesterol(p＜0.01), fat(p＜0.001), alcohol intake(p＜0.05),% energy of fat (p＜0.001), % energy of alcohol intake and level of and HDL-C(p＜0.001). Subjects who had serum TC, LDL-C, HDL-C, and TG levels greater than the standard reference values(TC＞240mg/㎗, LDL-C＞130mg/㎗, HDL-C＞35, TG＞200mg/㎗) exhibited a higher intake of the three macronutrients, iron, calcium, meat, milk and fatty foods than those subjects who had serum lipid concentrations less-than-or-equal-to the standard reference values. Overall, there was positive correlation between the high risk factors of vascular disease variables, dietary intake, and BMI. Prevalence of hypertension and high blood sugar were increased as BMI increased, but the prevalence of hypertension is decreased as the year goes by. These findings showed that dietary intake, level of serum lipids and other vascular disease risk factors increased as BIM increased. Therefore, middle or upper class Korean adults who have high BMI should improve their eating habits. This involve reducing alcohol, animal fat, high carbohydrate foods, and overall food intake, and balancing intake in order to lower vascular disease risk factors, including obesity.

• 대한본초학회지
• /
• 제27권4호
• /
• pp.1-7
• /
• 2012

Objectives : In this study, we investigated the effect of KOB, a polyherbal medicine for allergic rhinitis and its main herb, Astragali Radix on allergic responses in ovalbumin (OVA)-induced Allergic rhinitis(AR) mice. Methods : Sprague Dawley (SD)-rats were orally administrated with KOB (500 mg/kg), Astragali Radix water extract (ARW, 100 mg/kg) or anti-histamine drug, dosodium cromoglycate (50 mg/kg) as a reference drug, and then intraperitoneally injected with compound 48/80 (8 mg/kg). Rats were measured the mortality and serum levels of histamine. BALB/c mice were orally administrated with KOB (500 mg/kg), ARW (100 mg/kg) or anti-histamine drug, Ketotifen (10 mg/kg) as a reference drug, followed by sensitization and challenge of OVA. Mice were measured the serum levels of histamine and IgE, and observed histopathological changes of nasa mucosa H&E staining. Results : KOB and ARW significantly decreased the mortality and the serum levels of histamine in compound 48/80-induced anaphylatic rats. KOB and ARW also decreased the serum levels of histamine and IgE in OVA-induced AR mice, and inhibited histopathological changes of nasal mucosa with inflammation and the eosinophils infilteration. Conclusions : These data suggest that KOB has a strong anti-allergic effect through the inhibitory property of Astragali Radix, the main component of KOB against allergic responses in allergic rhinitis.

• Toxicological Research
• /
• 제22권1호
• /
• pp.47-54
• /
• 2006

One of the main attractions of treatment with herbal medicine is its apparent lack of side effects compared with the drug therapies used in allopathic medicine. However, evidence from various countries suggest that Asian herbal medicine carry a significant risk of contamination with toxic heavy metals at levels that may seriously threaten health. The aims of this study were to analyze and compare concentrations of heavy metals in urine and hair from 184 patients taking herbal medicines in the form of decoctions and/or pills in comparison to 101 control subjects taking either Western or no medications. Levels of metal concentrations exceeding WHO reference values were observed in a number of hair and urine samples for all subjects. After adjusting for potential confounders, taking decoctions or pills was associated with higher levels of some metals (such as Cu, Pb in urine), as well a higher odds ratio of exceeding the upper limit of reference ranges for Pb, Hg in hair. In contrast, taking decoctions or pills was associated with lower levels of some metals (such as Cu in urine and Cd, Cu, Hg, Pb in hair), suggesting that some herbal medicines may have a chelating effect on heavy metals in the body. Overall, the results obtained in the study show a mixed picture and suggest that heavy metals contamination in herbs is sometimes present, but may also be counteracted by the potential for some herbal medicines to act as chelating agents. Further study must be followed to obtain more concrete evidence.

• 한국환경보건학회지
• /
• 제41권4호
• /
• pp.231-240
• /
• 2015

Objectives: Blood mercury levels among adults living in certain areas of the Gyeongsang Provinces have been shown to be very high (Kunwee County $29.6{\mu}g/L$, Yeongcheon-city $26.7{\mu}g/L$). The purpose of this project was to determine mercury exposure levels in schoolchildren and factors related with their mercury levels in high mercury exposure areas identifyed by the 2007 Korea National Environmental Health Survey. Methods: From June to September 2010, 1,097 students from grades 3 to 6 at 19 elementary schools participated in this study, including 294 students from 10 elementary schools in Kunwee County, 529 students from Yeongcheon City, 122 students from two elementary schools in Pohang City, North Gyeongsang Province, and 152 students from two elementary schools in Ulsan Metropolitan City. Biological samples from schoolchildren, including whole blood, urine and hair, were collected to measure total mercury at the time of a health check up. Information about children was collected by questionnaire. Total mercury concentrations in blood were measured using the Direct Mercury Analyzer 80 with the gold-amalgam collection method. Results: The mean mercury levels were $2.70{\mu}g/L$ in 1,091 blood samples, $2.25{\mu}g/g-creat.$ in 820 urine samples and $1.03{\mu}g/g$ in 1,064 hair samples. Blood mercury levels in the schoolchildren was slightly higher than the result of $2.4{\mu}g/L$ from a 2006 survey of elementary school children on exposure and health effects of mercury by the National Institute of Environmental Research. However, 0.3% and 4.5% of participants exceeded the reference level of blood mercury by CHBMII ($15{\mu}g/L$) and the US EPA ($5.8{\mu}g/L$), respectively. The reference level of urine by CHBMII ($20{\mu}g/L$) was exceeded by 0.4% of participants. As factors, residence period in the study areas, residence type, father's education level and income all showed significant associations with mercury level in the biological samples. The number of dental amalgam sides showed an association with urine mercury. Fish intake preference and fish intake frequency were important factors in mercury levels. In particular, intake of shark meat and recent intake of shark meat were associated with higher mercury levels. In this regard, participation in the performance of an ancestral rite showed a relation with higher mercury levels. Conclusion: The intake of shark meat was very important factor to high mercury exposure level. It is recommended to monitor and manage students with high mercury exposures who exceeded CHBM II and EPA guidelines, and include blood mercury testing in the Children's Health check up for this province.

• Industrial Engineering and Management Systems
• /
• 제11권3호
• /
• pp.233-240
• /
• 2012

The implementation of business process management (BPM) systems in large number of business organizations transforms BPM system into such a level of maturity and tends to collect large repositories of business process (BP) models. This issue encourages BP flexibility that leads to a large number of process variants derived from the same model, but differing in structure, to be stored in the large repositories of BP models. Therefore, the repositories may include thousands of activities and related business objects with variation of requirements and quality of service. It is a common practice to customize processes from reference processes or templates in order to reduce the time and effort required to design and deploy processes on all levels. In order to address redundancy and underutilization problems, a generic process model, called as reference BP, is absolutely necessary to cover the best of process variants. This study aims to develop multiple-objective business process genetic algorithm (MOBPGA) to find a set of non-dominated (Pareto) solutions of business reference model to enhance conventional approach which considered only a single objective on creating BP reference model by using proximity score measurement. A mixed-integer linear program is constructed to evaluate performance of the proposed MOBPGA on small-scale problems by using standard measures for multiple-objective techniques. The results will show the viability of applying MOBPGA in terms of simultaneously maximizing proximity score measurement, minimizing total duration, and total costs of the selected reference model.

• Structural Engineering and Mechanics
• /
• 제53권5호
• /
• pp.957-979
• /
• 2015

The present paper investigates the influence of the orientation of the ground-motion reference axes, the seismic incident angle and the seismic intensity level on the inelastic response of asymmetric reinforced concrete buildings. A single storey asymmetric building is analyzed by nonlinear dynamic analyses under twenty bi-directional ground motions. The analyses are performed for many angles of incidence and four seismic intensity levels. Moreover three different pairs of the horizontal accelerograms corresponding to the input seismic motion are considered: a) the recorded accelerograms, b) the corresponding uncorrelated accelerograms, and c) the completely correlated accelerograms. The nonlinear response is evaluated by the overall structural damage index. The results of this study demonstrate that the inelastic seismic response depends on the orientation of the ground-motion reference axes, since the three individual pairs of accelerograms corresponding to the same ground motion (recorded, uncorrelated and completely correlated) can cause different structural damage level for the same incident angle. Furthermore, the use of the recorded accelerograms as seismic input does not always lead to the critical case of study. It is also shown that there is not a particular seismic incident angle or range of angles that leads to the maximum values of damage index regardless of the seismic intensity level or the ground-motion reference axes.

• Asian Journal of Atmospheric Environment
• /
• 제8권1호
• /
• pp.59-68
• /
• 2014

The Fukushima nuclear accident in 2011 had an extensive impact on the national electricity plans. This paper outlines alternative electricity scenarios that meet the goals of nuclear phase-out and greenhouse gas (GHG) emission reduction. This paper also analyzes the results of each scenario in respect to the electricity mix, GHG emissions, costs and employment effects. The Long-range Energy Alternatives Planning system (LEAP) model was used to simulate the annual electricity demand and supply system from 2011 to 2030. The reference year was 2009. Scenarios are reference (where existing plans are continued), A1, A2, B1, B2, and C2 (where the levels of demand management and nuclear phase-out are different). The share of renewable energy in the electricity mix in 2030 for each scenario will be increased from about 1% in 2009 to 8% in the reference scenario and from 11% to 31% in five alternative scenarios. Total cumulative cost increases up to 14% more than the reference scenario by replacing nuclear power plants with renewable energy in alternative scenarios could be affordable. Deploying enough renewable energy to meet such targets requires a roadmap for electricity price realization, expansion of research, development and deployment for renewable energy technologies, establishment of an organization dedicated to renewable energy, and ambitious targets for renewable energy.

• International Journal of Control, Automation, and Systems
• /
• 제6권3호
• /
• pp.327-338
• /
• 2008

A fault tolerant control system design technique has been proposed and analyzed for managing performance degradation in the presence of multiple faults in actuators. The method is based on a control structure with a model reference reconfigurable control design in an inner loop and command input adjustment in an outer loop. The reduced dynamic performance requirements in the presence of different actuator faults are accounted for through different performance reduced (degraded) reference models. The degraded steady-state performances are governed by the reduced levels of command input. The reconfigurable controller is designed on-line automatically in an explicit model reference control framework so that the dynamics of the closed-loop system follow that of the performance reduced reference model under each fault condition. The reduced command input level is determined to prevent potential actuator saturation. The proposed method has been evaluated and analyzed using an aircraft example against actuator faults subject to constraints on the magnitude and slew-rate of actuators.

• 한국문헌정보학회지
• /
• 제8권
• /
• pp.103-128
• /
• 1981

This study has two aims. one is to devide the ideology of reference service into three groups such as conservative, moderative, and progressive theories, and then investigate the validity of each theory as well as any problems to be suggested. The other is to establish appropriate standards of reference service according to the types of libraries and users, based on the analysis of such theories. Each theory has its own merits and demerits. Accordingly, it seems to be difficult to apply uniformly and theory into users who have different types of question and educational levels. And also it is difficult to apply into various libraries which have different aims of establishment, characteristics, and the users of each library. Consequently, it is suggested to set up a norm of reference service according to the types of libraries and users respectively. The conservative theory is applicable to small and medium sized public libraries, school libraries, and college and university libraries of which the users are mainly students and citizens. The progressive theory is desirable for special and academic libraries as well as large public libraries where the users are mainly specialists. and scholars.

• Journal of Multimedia Information System
• /
• 제9권2호
• /
• pp.75-86
• /
• 2022

The existing image quality assessment (IQA) datasets have a small number of samples. Some methods based on transfer learning or data augmentation cannot make good use of image quality-related features. A No Reference (NR)-IQA method based on multi-task training and quality awareness is proposed. First, single or multiple distortion types and levels are imposed on the original image, and different strategies are used to augment different types of distortion datasets. With the idea of weak supervision, we use the Full Reference (FR)-IQA methods to obtain the pseudo-score label of the generated image. Then, we combine the classification information of the distortion type, level, and the information of the image quality score. The ResNet50 network is trained in the pre-train stage on the augmented dataset to obtain more quality-aware pre-training weights. Finally, the fine-tuning stage training is performed on the target IQA dataset using the quality-aware weights to predicate the final prediction score. Various experiments designed on the synthetic distortions and authentic distortions datasets (LIVE, CSIQ, TID2013, LIVEC, KonIQ-10K) prove that the proposed method can utilize the image quality-related features better than the method using only single-task training. The extracted quality-aware features improve the accuracy of the model.