• 한국세라믹학회지
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• 제15권2호
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• pp.85-88
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• 1978

Influence of cooling atmosphere on the whiteness in white portland cement was studied. The effective composition of gaseous medium of cooling atmosphere is desirable less than 0.5% of $O_2$ and 0.5~1.5% of CO. When theclinker is quenched in nitrogen atmosphere, the color of clinker becomes bright pink. In a weakly reducing gaseous medium or vacuum, the absence of oxygen brings defects in crystal and transformation in the coordination of iron, and as a result, whiteness is raised.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1989년도 하계종합학술대회 논문집
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• pp.685-688
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• 1989

This paper presents two methods for reducing the position error of the robot hand. The first method change the parameters of the D-H transformation using real position error. The other one calibrates the joint angle by using the datas from the known teaching points. SCARA type robot is used for verifing the validity of the proposed methods.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2003년도 하계종합학술대회 논문집 II
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• pp.1157-1160
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• 2003

We proposed a study on optimal clock period selection algorithm for low power RTL design. The proposed algorithm use the way of maintaining the throughput by reducing supply voltage after improve the system performance in order to minimize the power consumption. In this paper, it select the low power to use pipeline in the transformation of architecture. Also, the algorithm is important the clock period selection in order to maximize the resource sharing. however, it execute the optimal clock period selection algorithm.

• Bulletin of the Korean Chemical Society
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• 제3권2호
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• pp.76-78
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• 1982

Ethanolic tetracarbonylhydridoferrate solution combined with glutaraldehyde is a very effective reducing agent for the selective transformation of two moles of secondary amines into pentane-1,5-diamine derivatives. A variety of aliphatic secondary amines react with ferrate-glutaraldehyde at room temperature under carbon monoxide to give the corresponding N-substituted pentane-1,5-diamines in reasonable yields.

• BMB Reports
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• 제51권9호
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• pp.474-479
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• 2018

Cisplatin is one of the most effective chemotherapeutic drugs used in the treatment of HCC, but many patients will ultimately relapse with cisplatin-resistant disease. Used in combination with cisplatin, resveratrol has synergistic effect of increasing chemosensitivity of cisplatin in various cancer cells. However, the mechanisms of resveratrol enhancing cisplatin-induced toxicity have not been well characterized. Our study showed that resveratrol enhances cisplatin toxicity in human hepatoma cells via an apoptosis-dependent mechanism. Further studies reveal that resveratrol decreases the absorption of glutamine and glutathione content by reducing the expression of glutamine transporter ASCT2. Flow cytometric analyses demonstrate that resveratrol and cisplatin combined treatment leads to a significant increase in ROS production compared to resveratrol or cisplatin treated hepatoma cells alone. Phosphorylated H2AX (${\gamma}H2AX$) foci assay demonstrate that both resveratrol and cisplatin treatment result in a significant increase of ${\gamma}H2AX$ foci in hepatoma cells, and the resveratrol and cisplatin combined treatment results in much more ${\gamma}H2AX$ foci formation than either resveratrol or cisplatin treatment alone. Furthermore, our studies show that over-expression of ASCT2 can attenuate cisplatin-induced ROS production, ${\gamma}H2AX$ foci formation and apoptosis in human hepatoma cells. Collectively, our studies suggest resveratrol may sensitize human hepatoma cells to cisplatin chemotherapy via gluta${\gamma}H2AX$mine metabolism inhibition.

• Journal of Microbiology and Biotechnology
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• 제26권11호
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• pp.1924-1932
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• 2016

Mycophenolic acid (MPA) is an antibiotic produced by Penicillium brevicompactum. MPA has antifungal, antineoplastic, and immunosuppressive functions, among others. ${\beta}-Hydroxy-{\beta}-methylglutaryl-CoA$ (HMG-CoA) lyase is a key enzyme in the bypass metabolic pathway. The inhibitory activity of HMG-CoA lyase increases the MPA biosynthetic flux by reducing the generation of by-products. In this study, we cloned the P. brevicompactum HMG-CoA lyase gene using the thermal asymmetric interlaced polymerase chain reaction and gene walking technology. Agrobacterium tumefaciens-mediated transformation (ATMT) was used to insert a mutated HMG-CoA lyase gene into P. brevicompactum. Successful insertion of the HMG-CoA lyase gene was confirmed by hygromycin screening, PCR, Southern blot analysis, and enzyme content assay. The maximum MPA production by transformants was 2.94 g/l. This was 71% higher than wild-type ATCC 16024. Our results demonstrate that ATMT may be an alternative practical genetic tool for directional transformation of P. brevicompactum.

• 한국음향학회지
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• 제42권2호
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• pp.102-111
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• 2023

자동 음악 채보는 주어진 오디오에서 음표 정보를 추출하는 태스크로, 이 연구에서는 피아노 음악의 자동음악 채보 모델에서 지연 시간을 줄이는 방법을 소개한다. 신경망 기반 채보 모델이 피아노 채보에도 적용되어 높은 정확도를 기록하였고 이를 이용한 실시간 구현도 소개된 바 있지만, 채보를 위한 지연 시간이 길어 인터랙티브 시나리오에서 활용하기에 한계가 있었다. 이 문제를 해결하기 위해 본 연구는 Fast Fourier Transformation(FFT)에서 윈도우 크기와 홉 크기를 줄이거나 합성곱 레이어의 커널 크기를 수정하고 시간 축에서 레이블을 이동하여 모델이 시작을 더 일찍 예측하도록 훈련하는 등 피아노 전사를 위한 신경망의 내재적 지연 시간을 줄이는 몇 가지 기술을 제안한다. 실험 결과, 이러한 접근 방식을 결합하면 높은 전사 정확도를 유지하면서 지연 시간을 줄일 수 있음을 알 수 있었다. 기존 모델은 160 ms의 지연 시간을 가지고 음표 F1 점수는 93.43 %였으나 제안한 방법을 적용하면 96 ms와 64 ms의 지연 시간 동안 각각 92.67 %와 90.51 %의 F1 점수를 달성할 수 있었다. 이러한 결과는 향후 피아노 교육을 위한 실시간 피드백 제공 등 다양한 인터랙티브 시나리오를 위한 자동 채보 모델에 활용될 수 있을 것이다.

• 한국품질경영학회:학술대회논문집
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• 한국품질경영학회 1998년도 The 12th Asia Quality Management Symposium* Total Quality Management for Restoring Competitiveness
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• pp.309-315
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• 1998

Process Capability can be expressed with a process index which indicates the incapability of a process to meet its specifications. This index is regarded as a process capability index(PCI) or more precisely as a process incapability index(PII). It is obtained from a simple transformation of a PCI. Greenwich and Jahr-Schaffrath(1995) considered the PII $C_{pp}$ which could be obtained from the transformation to the PCI, $C_{pm}$, and they provided the asymptotic distribution for $C_{pp}$ which was useful unless the process characteristic was normally distributed. However, some statistical inferences based on the asymptotic distribution need a large sample size. There are some processes which process engineers could not help obtaining sufficiently a large sample size. Thus, we have derived its corresponding bootstrap asymptotic distribution since bootstrapping would be a helpful technique for the PII, $C_{pp}$ which was nonparametric or free from assumptions of the distribution of the characteristic X. Moreover, we have constructed six bootstrap confidence intervals used in reducing bias of estimations based on the bootstrap asymptotic distribution and simulated their performances for $C_{pp}$,

• 한국정밀공학회지
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• 제33권7호
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• pp.551-558
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• 2016

Reduction of welding residual stress is very important in the railway industry, but calculating its distribution in structures is difficult because welding residual stress formation is influenced by various parameters. In this study, we developed a finite element model for simulating the repair welding process to recover a surface damaged rail, and conducted a series of parametric studies while varying the cooling rate and the duration of post weld heat treatment (PWHT) to find the best conditions for reducing welding residual stress level. This paper presents a three-dimensional model of the repair welding process considering the phase transformation effect implemented by the ABAQUS user subroutine, and the results of parametric studies with various cooling rates and PWHT durations. We found that heat treatment significantly reduced the residual stress on the upper rail by about 170 MPa.

• 방송공학회논문지
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• 제17권2호
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• pp.284-294
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• 2012

본 논문은 OLED 디스플레이를 위한 저전력 화질 개선 기법을 제안한다. 제안하는 알고리즘은 영상의 대조비를 향상하면서 동시에 OLED 디스플레이의 소비 전력을 감소하는 변환을 선형 변환 함수에 기반하여 유도한다. 또한 영상의 지역적 특성을 고려하여 블록 단위로 변환 함수를 적용하여 영상의 지역적 특성에 적응적인 대조비 개선 알고리즘을 개발한다. 컴퓨터 모의실험을 통해 제안하는 알고리즘이 전력 소비를 줄이고 동시에 영상의 대조비를 향상시키는 것을 확인한다.