• Title/Summary/Keyword: Ray Method

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Application of Gamma Irradiation on Manufacturing Changran Jeotgal (aged and seasoned intestine of Alaska pollack) : Microbiological and Sensory Characteristics (양념 창란젓갈 제조시 감마선 조사기술 적용: 미생물학적 및 관능적 품질특성)

  • Jo, Cheorun;Kim, Dong-Ho;Lee, Won-Dong;Lee, Jae-Jin;Byun, Myung-Woo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.5
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    • pp.673-678
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    • 2003
  • Changran Jeotgal (aged and seasoned intestine of Alaska pollack) was prepared as the same method as commercial one and irradiated at 0, 2.5, 5.0 and 10 k㏉ by gamma ray for industrial application. Changran Jeotgal using 10 k㏉-irradiated red pepper powder was also prepared to compare with control (0 k㏉). Commercial red pepper powder was already contaminated at 3.8$\times$10$^{6}$ CFU/$m\ell$ level by total plate count and 10k㏉ of irradiation reduced the number about 4 log cycles. Gamma irradiated Changran Jeotgal at 2.5,5.0, and 10k㏉ showed 3 6, and 7 log cycles of reduction compared to the non-irradiated control in the total plate count after 12 weeks of storage at 1$0^{\circ}C$. Using irradiated (10k㏉) red pepper powder reduced the microbial contamination significantly by 2 log cycles compared to the control. Sensory evaluation showed that the sample irradiated at 2.5 k㏉ was the most acceptable, followed by the sample using irradiated red pepper powder and non-irradiated control. Thus, 2.5 k㏉ of irradiation of Changran Jeotgal was effective to improve safety during distribution and storage without change of sensory quality. Furthermore, using the irradiated red pepper powder is also recommended for safety enhancement of the products.

NMR Studies on the Structure of Human Annexin I

  • Han, Hee-Yong;Bang, Keun-Su;Na, Doe-Sun;Lee, Bong-Jin
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.182-182
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    • 1996
  • Annexin I is a member of the annexin family of calcium dependent phospholipid binding proteins and has anti-inflammatory activity by inhibiting phospholipase A$_2$ (PLA$_2$). Recent X-ray crystallographic study of annexin I identified six Ca$\^$2+/ binding bites, which was different types (type II, III) from the well-known EF-hand motif (type I). In this work, the structure of annexin I was studied at atomic level by using $^1$H, $\^$15/N and $\^$l3/C NMR(nuclear magnetic resonance) spectroscopy, and the effect of Ca$\^$2+/ binding on the structure of annexin I was studied, and compared with that of Mg$\^$2+/ binding, When Ca$\^$2+/ was added to annexin I, NMR peak change was occured in high- and low-field regions of $^1$H-NMR spectra. NMR peak change by Ca$\^$2+/ binding was different from that by Mg$\^$2+/ binding. Because annexin I is a larger protein with 35 kDa molecular weight, site-specific (amide-$\^$15/N, carbonyl-$\^$l3/C) labeling technique was also used. We were able to detect methionine, tyrosine and phenylalanine peaks respectively in $\^$13/C-NMR spectra, and each residue was able to be assigned by the method of doubly labeling annexin I with [$\^$13/C] carbonyl-amino acid and [$\^$15/N] amide-amino acid. In $\^$l3/C-NMR spectra of [$\^$13/C] carbonyl-Met labeled annexin I, we observed that methionine residues spatially located near Ca$\^$2+/ binding Sites Were Significantly effected by Ca$\^$2+/ binding. From UV spectroscopic data on the effect of Ca$\^$2+/ binding, we knew that Ca$\^$2+/ binding sites of annexin I have cooperativity in Ca$\^$2+/ binding. The interaction of annexin I with PLA$_2$ also could be detected by using heteronuclear NMR spctroscopy. Consequently, we expect that the anti-inflammatory action mechanism of annexin I may be a specific protein-protein interaction. The residues involved in the interaction with PLA$_2$ can be identified as active site by assigning NMR peaks effected by PLA$_2$ binding.

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Treatment of Ossifying Fibroma (화골성 섬유종의 치료)

  • Jung, Sung-Taek;Chung, Jae-Yoon;Song, Eun-Kyoo;Park, Yong-Cheol
    • The Journal of the Korean bone and joint tumor society
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    • v.9 no.1
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    • pp.61-68
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    • 2003
  • Purpose: We reviewed the outcome of treatment of ossifying fibroma involving long bones. Materials and methods: Eight patients who enrolled at our hospital for ossifying fibroma from 1994 to 1999 were selected for this study. Mean age was 7.9 years old. Five were male and three female. Seven involved tibia and one fibula. All cases were diagnosed by biopsy. The initial treatment was conservative and the followings were operative indications; (1) repeated fracture, (2) suddenly growing mass, (3) severe bowing deformity, (4) pseudoarthrosis. We assessed the recurrence by x-ray follow-up. Results: As initial treatment, curettage was performed in 2 patients, observation in 2 subperiosteal resection in one and extraperiosteal resection in 3 patients. Two patients who were observed and 3 patients who received extraperiosteal resection did not suffer recurrence. Two patients who received curettage and one patient who received subperiosteal resection had recurrence. The second treatment was performed in 3 patients. The one case of curettage received extraperiosteal resection. The other was in observation. The case of subperiosteal resection was in observation, too. There were no recurrence and aggravation at follow-up. Conclusion: Ossiying fibroma should to be treated by conservative method. If operation is indicated, extraperiosteal resection could reduce the recurrence.

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Nutritional Factors Related to Bone Mineral Density in the Different Age Groups of Korean Women (한국 여자의 연령별 골밀도에 영향을 미치는 영양요인 분석)

  • 유춘희;이정숙;이일하;김선희;이상선;정인경
    • Journal of Nutrition and Health
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    • v.35 no.7
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    • pp.779-790
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    • 2002
  • Nutritional factors affecting bone mineral density (BMD) in the different age groups of Korean women were investigated to obtain baseline data for maintaining bone health. Information on diet and anthropometry were collected in 80 elementary school children (height 127.2 cm, weight 27.3 kg), 84 high school students (height 161.6 cm, weight 52.4 kg), 100 adults aged 25 to 35 years (height 159.4 cm, weight 52.7 kg) and 120 elderly people over 60 years of age (height 150.9 cm, weight 55.6 kg). Data for nutrient intake were obtained by 24-hour recall method. BMDs of lumbar spine (L$_2$-L$_4$) and femoral neck were measured by dual energy x-ray absorptiometry. The relationship between BMD of femoral neck and nutritional factors were analyzed. The average BMD of femoral neck for females was 0.61 g/$\textrm{cm}^2$ in children, 0.88 g/$\textrm{cm}^2$ in adolescents, 0.90 g/$\textrm{cm}^2$ in adults, 0.64 g/$\textrm{cm}^2$ in elderly people. Among the adult subjects, 11.0% was classified as osteopenia in the femoral neck. For the elderly, the prevalence of osteopenia and osteoporosis were 34.2% and 47.5% of the subjects. It was shown the intake of energy, protein, plant protein, animal protein, fat, carbohydrate, Ca, P, Fe, vitamin A, thiamin, riboflavin, niacin, vitamin C, carbohydrate energy percent and fat energy percent influenced bone health status in all age groups. In the MAR on bone health status, children, adult and elderly subjects were significantly different among groups classified by bone health status and the MAR of the groups with good in bone health was higher. The RDA percent of each nutrient was influence factor on BMD. Nutrient intake of energy, protein, P, Fe, thiamin, niacin were lower BMD on below 75% of Korean RDA. Stepwise multiple regression analysis revealed that several dietary factors were influence on BMD. MAR on femoral neck BMD of children and elderly subjects was the highest influence factor. Beyond this, the most influential dietary factors on BMD were the vitamin A, total Ca and vegetable Ca. The above results have confirmed that dietary factors influence BMD in various age groups. Energy, protein, Ca, P, Fe, thiamin, riboflavin, niacin, vitamin C as well as MAR were important dietary factors influencing BMD. The results of this study revealed that people who received sufficient nutrients intake showed healthy bone status. The MAR mainly influenced the bone health status.

Depth Upsampling Method Using Total Generalized Variation (일반적 총변이를 이용한 깊이맵 업샘플링 방법)

  • Hong, Su-Min;Ho, Yo-Sung
    • Journal of Broadcast Engineering
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    • v.21 no.6
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    • pp.957-964
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    • 2016
  • Acquisition of reliable depth maps is a critical requirement in many applications such as 3D videos and free-viewpoint TV. Depth information can be obtained from the object directly using physical sensors, such as infrared ray (IR) sensors. Recently, Time-of-Flight (ToF) range camera including KINECT depth camera became popular alternatives for dense depth sensing. Although ToF cameras can capture depth information for object in real time, but are noisy and subject to low resolutions. Recently, filter-based depth up-sampling algorithms such as joint bilateral upsampling (JBU) and noise-aware filter for depth up-sampling (NAFDU) have been proposed to get high quality depth information. However, these methods often lead to texture copying in the upsampled depth map. To overcome this limitation, we formulate a convex optimization problem using higher order regularization for depth map upsampling. We decrease the texture copying problem of the upsampled depth map by using edge weighting term that chosen by the edge information. Experimental results have shown that our scheme produced more reliable depth maps compared with previous methods.

Characteristics and Genesis of the Clay Minerals in Weathering Products from the Guweol Mountain Area, Pusan (부산시(釜山市) 구월산(九月山)의 풍화물중(風化物中) 점토광물(粘土鑛物)의 특성(特性) 및 성인(成因))

  • Hwang, Jin-Yeon;Jang, Myoung-Ik
    • Korean Journal of Soil Science and Fertilizer
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    • v.27 no.3
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    • pp.158-167
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    • 1994
  • The various weathering products derived from andesitic rocks in the Guweol mountain area of Pusan have been studied in order to investigate the occurrence, characteristics and evolutional trend of clay minerals in the weathered rock and soil using mainly X-ray powder diffraction method. Kaolinite and halloysite are very abundant in the weathered rocks and soils derived from andesitic rocks of this area. Also, $12{\AA}$- and $14{\AA}$-minerals occur in the considerable amount. $12{\AA}$-minerals have been identified as mica/vermiculite interlayer minerals showing the $25{\AA}$ basal reflection. Their crystal sizes are relatively big showing more than 10 micron in diameter. Two types of $14{\AA}$-mineral, which are vermiculite/smectite interlayer mineral and Al-vermiculite, have been observed. Kaolin minerais consist of kaolinite, $10{\AA}$ and $7{\AA}$ halloysite. Kaolinite relatively dominates in the strongly weathered soil of the area. In contrast with kaolinite. $12{\AA}$- and $14{\AA}$-minerals such as vermiculite/smectite and mica/vermiculite interlayer minerals tend to occur in the weakly to intermediately weathered products. Based on their occurrences, it strongly suggests that they are intermediate products in the course of the weathering process from the parent materials into the kaolin mineral.

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The Study of Effectiveness in a Modified Rib Oblique Projection View Using a Chest Phantom (흉부팬텀을 이용한 변형된 늑골 사방향 검사의 유용성에 관한 연구)

  • Um, Ki-Tae;Lee, Min-Su;Kang, Sung-Jin
    • Journal of the Korean Society of Radiology
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    • v.12 no.4
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    • pp.525-532
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    • 2018
  • This study is filmed by applying the axial angle variation of the X-ray tube instead of the patient's position change during the perimetric examination of the ribs. A Reference image with the rib oblique examination using a chest phantom and experimental images applied with a six-phase variation in the axial angle by increasing $5^{\circ}$ tube angle each from $5^{\circ}{\sim}30^{\circ}$ from the vertical incident direction of the chest phantom to the right horizontal axis were obtained. For the quantitative comparative evaluation of the images, SNR and CNR were calculated for regions of interest in the experimental images based on the reference image. Also, the left-right rib ratio in the reference image and the left-right rib ratio in the experimental images are measured and compared. As a result of the study, the experimental images with a tube angle of $25^{\circ}$ were best shown in the measurements of the SNR, CNR and left-right rib ratio compared to the reference image with a standard examination method. The modified rib examinations will consider useful, if it is difficult to maintain the patient's examination position.

Inactivation of Xanthomonas citri subsp. citri and Effect on Infection of Citrus Canker by Gamma Irradiation (감마선에 의한 감귤 궤양병균의 불활성화와 감귤 궤양병 감염에 미치는 영향)

  • Kim, Kyung Nam;Song, Min A;Han, Sang Heon;Song, Seong Joon;Jeun, Yong Chull
    • Research in Plant Disease
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    • v.20 no.4
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    • pp.283-288
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    • 2014
  • Citrus canker caused by Xanthomonas citri subsp. citri (Xcc) has been quarantined by many countries in the world. Recently, the usage of methyl bromide should be limited, application by gamma irradiation on the agricultural production is raised as an alternative method. In this study, the level of gamma irradiation which could decrease of population of Xcc in the suspension or on the surface of citrus fruit was investigated. The $D_{10}$ value of Xcc, which is radiation dose required to reduce the number of the microorganism, was 55 and 28 Gy in the suspension and on the surface of citrus fruit, respectively. Furthermore, disease severity was suppressed on the citrus leaves inoculated with Xcc suspension pre-treated with gamma irradiation. Based on this study, it is suggested that Xcc on the citrus fruit could be eradicated by gamma irradiation and the results of this study may be valuable for application of gamma ray in quarantine activity.

Evaluation of Lymph Node Staging of Chest CT in NSCLCa (비소세포 폐암의 임파절 병기판정에 대한 흉부 전산화 단층 촬영의 효용성 연구)

  • Sung, Sook-Whan;Kim, Young-Tae;Kim, Doo-Sang;Kim, Joo-Hyun;Lim, Jung-Ki
    • Journal of Chest Surgery
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    • v.31 no.3
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    • pp.271-278
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    • 1998
  • In order to access the value of computed tomography in mediastinal LN staging of NSCLCa, 581 LN stations of 77 patients were selected from 552 patients who were diagnosed as Lung Ca and operated in Seoul National University Hospital from 1992 to 1995. The selection criteria were as follows ; the patients 1) whose preoperative chest CTs were available; 2) underwent curative resection (lobectomy or more) with complete lymph node dissection; 3) whose final pathologic diagnosis were proven to be non-small cell lung cancer. We adopted Receiver Operating Characteristic curve method to determine a proper size criterion for diagnosing malignant mediastinal adenopathy. From curve analysis, we decided the size criterion of lymph node to 1 cm in their short axis. Using this size criterion, it's sensitivity was 43.9%, specificity was 87.4%, and accuracy was 83.1%. Eventhough we couldn't determine the precise size criterion for the adenoca, it seemed that shorter than 1 cm size criterion should be applied in that particular cell type. Lymph node stations associated with the tuberculosis or bronchiectasis tend to be overestimated in nodal staging and have relatively high false positive rate. The low sensitivity of CT scan suggest that radical and complete dissection or precise mediastinal lymph node evaluation through the surgical approach is mandatory.

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Noninvasive Evaluation of Coronary Artery Bypass Graft Patency by Electron Beam Tomography (전자선 단층 촬영을 이용한 관상동맥 우회로 개존의 비침습적 평가)

  • 최규옥;김호석;조범구
    • Journal of Chest Surgery
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    • v.32 no.8
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    • pp.693-701
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    • 1999
  • Recently non-invasive diagnostic imaging replaced the invasive catheter angiography in the diagnosis of vascular disease. Catheter methods are now almost confined to the purpose of intervention. Coronary artery or coronary artery bypass graft still needs catheter technique because of small diameter and the cardiac motion. The last challenge for radiologists in this domain is to obtain a non-invasive imaging. Electron beam tomography(EBT) for high temporal resolution is able to obtain a coronary arteriogram or coronary artery bypass graft (CABG), of which CABG imaging is quite useful for the evaluation of patency. In our experience as well as others, the accuracy of EBT angiogram in evaluating CABG patency revealed that the accuracy of patency of saphenous vein grafts(SVG) is high due to relatively wide lumen, short and straight course and less influence from cardiac motion. The sensitivity and specificity of patency of SVGs were 92%, 97% respectively in the prospective evaluat on and 100% each in the retrospective evaluation. A false positive and a false negative case are rudimentary errors in the initial learing period. In contrast the analysis of left internal mammary artery(LIMA) graft was difficult due to the inherent small size and the adjacent surgical clips provoking beam-hardening artifact; therefore, the method of combining 3 dimensional reconstruction and flow mode study was important in improving the accuracy of LIMA patency. The sensitivity and specificity of LIMA patency were 100% and 80% in both prospective and retrospective evaluation. Therefore, EBT angiography is an accurate non-invasive diagnostic modality for evaluating the patency of CABG, particularly in SVGs. The accuracy can be improved with the improvement of the EBT and the development of the image reconstruction software.

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