• Title/Summary/Keyword: Rapid commercialization

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Physiological properties of grape cluster portions between cultivars and the effect of postharvest cooling on the marketability (포도 품종간 송이 부위별 생리적 특성과 수확 후 냉각과 유통성 관계)

  • Min, Jeong-Ho;Lim, Byung-Seon;Choi, Yeon-Soo;Lee, Kyung-Min;Kim, Dal-Woo;Hwang, Yong-Soo
    • Korean Journal of Agricultural Science
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    • v.39 no.1
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    • pp.1-8
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    • 2012
  • Rapid loss of grape berry quality after harvest occurs due to poor postharvest management. Understanding physiological properties between cultivars is required to develop practical technologies to control fast quality deterioration of tables grapes. Physiological characteristics of whole cluster, rachis and berries were examined to find their effects on postharvest behaviour of table grapes. 'Tamnara' showed high respiration rate and browning of rachis compared to 'Campbell Early'. Weight loss of rachis of 'Cheongsoo' was highest of three cultivars. Berry decay in 'Cheongsoo' begins at the connection portion between peduncle and berry, and berry decay of 'Cheongsoo' was the most severe among three cultivars. Precooling at $0^{\circ}C$ showed better results than cooling at $10^{\circ}C$ regardless of cultivars but cooling effect decreased when simulated marketing period increased up to 10 days. Plastic film wrapping was effective on reducing decay in general but not at higher marketing temperature. For successful commercialization of newly developed grapes, the inhibition technology of rachis browning in 'Tamnara' is required and decay control in 'Cheongsoo' through establishment of cold chain system is recommended.

Effect of equivalence ratio on operation of 3MWth circulating fluidized bed for biomass gasification (3MWth급 순환유동층 바이오매스 가스화기의 운전에서 Equivalence ratio 영향)

  • Park, Seongbum;Lee, Jeoungwoo;Song, Jaehun;Pak, Daewon
    • Journal of the Korean Applied Science and Technology
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    • v.34 no.1
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    • pp.58-65
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    • 2017
  • Fluidized bed gasification is technically and economically proven technology, which shows the high possibility of realization and commercialization. However, in Korea, development of FBG to the commercial scale for power generation and industry is mainly blocked by the fact that there is no experience of design, troubleshooting and operation of even pilot scale fluidized bed gasifier. In this study, a $3MW_{th}$ circulating fluidized bed(CFB) was newly developed for biomass gasification. The fluidized bed was mainly composed of circulating and bubbling fluidized reactors integrating in-situ tar removal step in the system. For cleaning of the tar and acid gas in the product gas, the sequential gas cleaning process comprised of a ceramic filter, rapid quencher and wet scrubber was adopted. Effect of equivalence ratio was investigated to find the optimal operating conditions for the $3MW_{th}$ integrated system of fluidized bed gasification.

A Survey Study on a Activating Strategy for College Academia-industrial Cooperation with Industry's Needs for 3D Printing and College Graduate (3D 프린팅과 전문대학 인력에 대한 기업 수요조사를 통한 전문대학 산학협력 활성화 방안 연구)

  • Ryu, Chung-Hyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.3
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    • pp.57-65
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    • 2016
  • Academia-industrial cooperation policy is essential to enhance national competitiveness in Korea. Although government and academia have invested in policies and supported industries, academia-industrial cooperation is not operated actively. This is one of the reasons why industrial demand for cooperation has continuously decreased. There are thoughts that universities' outcomes are larger than colleges' outcomes in academia-industrial cooperation, which could be a barrier to academia-industrial cooperation for colleges. It is important to understand industry demands in order to activate this type of cooperation. We propose a way to achieve this based on survey data for 3D printing and college graduates. Interactive cooperation among industries, colleges, and universities is suggested in the process of technical commercialization, such as TRL (Technology Readiness Level).

Analytical comparison of structural changes of plastic cell-based therapeutic drug storage containers when exposed to cryogenic environments (플라스틱 세포치료제 보관용기의 극저온 환경 노출 시 구조적 변화에 대한 해석적 비교)

  • Park, Jeong-Yeon;Lee, Dong-Mok;Lee, Jienny;Lee, Sun-ray;Yoon, Gil-Sang
    • Design & Manufacturing
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    • v.14 no.2
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    • pp.1-6
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    • 2020
  • Recently, research and commercialization related to the field of cell-based therapeutic drug development has been actively conducted. In order to maintain cell viability and prevent contamination, refrigeration preservation devices, such as CRF (controlled rate freezer) or vapor type LN2 tanks have been developed. On the other hand, the storage container for liquid nitrogen tanks currently on sale minimizes the flow structure to prevent structural defects when stored in a liquid nitrogen tank having a high thermal conductivity than vapor nitrogen. If the cell-based treatment drug is stored in the gaseous LN2 tank as it is, the cell survival after thawing is greatly reduced. It was estimated that the existing storage container structure was a factor that prevented the rapid entry and circulation of gaseous nitrogen into the container. Therefore, this study intends to propose a new supercellular storage container model that can maintain the mechanical strength while maximizing the fluid flow structure. To this end, we estimated that the structural change of the storage container effects on the equivalent stress formed around the through-holes of them when exposed to a cryogenic environment using thermal-structural coupled field analysis. As a result of storage experiments in the gas phase tank of the cell-based therapeutic agent using the developed storage container, it was confirmed that the cell growth rate was improved from 66% to 77%, which satisfied the transportation standards of the FDA(Food and Drug Administration) cell-based therapeutic agent.

Effect of Low Temperature Preservation and Cell Density on Metabolic Function in a Bioartificial Live

  • Park, Yueng-Guen;Takehiko Tosha;Satoshi Fujita;Boru Zhu;Hiroo Iwata;Ryu, Hwa-Won
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.8 no.1
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    • pp.41-46
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    • 2003
  • Difficulties associated with bioartificial liver (BAL) preservation limit not only the commercialization of BAL, but also its clinical trials. In this study, the possibility of cold preservation of BAL cartridges containing porcine hepatocytes was examined at 4$^{\circ}C$. In an in vitro perfusion culture System, BAL cartridges maintained cytochrome P450 metabolic function for at least 50 days. However, all BAL cartridges completely lost their ammonia eliminating ability when stored at 4$^{\circ}C$. We a1so studied the effect of cell density on the maintenance of BAL liver function In a highly differentiated and healthy state. As expected, BALs containing a larger number of hepatocytes demonstrated higher metabolic functions. When metabolic functions were compared per gram of hepatotytes, no large differences were observed between devices containing different densities of hepatocytes. Decreased cell density did not Successfully prolong BAL function. The viability and function of isolated hepatotytes highly depend on the culture conditions, such as cell density, substrata, culture media, and additives to the culture media. Perfusion culture of BAL cartridges at 4$^{\circ}C$ gave a promosing result with respect to the maintenance of P450 activity. However, as indicated by the rapid loss of ammonia metabolic activity, many factors still remain to be optimized for preservation of BAL keeping high metabolic functions for a longer time.

Rapid and Nondestructive Discrimination of Fusarium Asiaticum and Fusarium Graminearum in Hulled Barley (Hordeum vulgare L.) Using Near-Infrared Spectroscopy

  • Lim, Jong Guk;Kim, Gi Young;Mo, Chang Yeun;Oh, Kyoung Min;Kim, Geon Seob;Yoo, Hyeon Chae;Ham, Hyeon Heui;Kim, Young Tae;Kim, Seong Min;Kim, Moon S.
    • Journal of Biosystems Engineering
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    • v.42 no.4
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    • pp.301-313
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    • 2017
  • Purpose: This study was conducted to discriminate between normal hulled barley and Fusarium (Fusarium asiaticum and Fusarium graminearum) infected hulled barley by using the near-infrared spectroscopy (NIRS) technique. Methods: Fusarium asiaticum and Fusarium graminearum were artificially inoculated in hulled barley and the reflectance spectrum of the barley spike was obtained by using a near-infrared spectral sensor with wavelength band in the range 1,175-2,170 nm. After obtaining the spectrum of the specimen, the hulled barley was cultivated in a greenhouse and visually inspected for infections. Results: From a partial least squares discriminant analysis (PLS-DA) prediction model developed from the raw spectrum data of the hulled barley, the discrimination accuracy for the normal and infected hulled barley was 99.82% (563/564) and 100% (672/672), respectively. Conclusions: NIRS is effective as a quick and nondestructive method to detect whether hulled barley has been infected with Fusarium. Further, it expected that NIRS will be able to detect Fusarium infections in other grains as well.

Impact of quorum quenching bacteria on biofouling retardation in submerged membrane bioreactor (SMBR)

  • Pervez, Saimar;Khan, Sher Jamal;Waheed, Hira;Hashmi, Imran;Lee, Chung-Hak
    • Membrane and Water Treatment
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    • v.9 no.4
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    • pp.279-284
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    • 2018
  • Membrane biofouling is a critical operational problem that hinders the rapid commercialization of MBRs. Quorum quenching (QQ) has been investigated widely to control membrane biofouling and is accepted as a promising anti-fouling strategy. Various QQ strategies based on bacterial and enzymatic agents have been identified and applied successfully. Whereas, this study aimed to compare indigenously isolated QQ strain i.e., Enterobacter cloaca with well reported Rhodococcus sp. BH4. Both bacterial species were immobilized in polymeric beads and introduced to two different MBRs keeping the overall beads to volume ratio as 1%. Efficiencies of these strains were monitored in terms of prolonging the membrane filtration cycle of MBR, release of extra-cellular polymeric substances, membrane resistivity measurements and mineralization of signal molecules and permeate quality. Indigenous strain (Enterobacter cloaca) was added to $QQ-MBR_E$ while Rhodococcus sp. BH4 was introduced to $QQ-MBR_R$. QQ bacterial embedded beads showed enhanced filtration cycles up to 1.4 and 2.3 times for $QQ-MBR_E$ and $QQ-MBR_R$ respectively as compared to control MBR (C-MBR). Soluble EPS concentration of 52 mg/L was observed in C-MBR while significantly lower EPS concentration of 20 and 10 mg/L was witnessed in $QQ-MBR_E$ and $QQ-MBR_R$, respectively. Therefore, substantial reduction in biofouling showed the effectiveness of indigenous strain.

Study on the meaning of Architectural Growth in Carlos Jim$\acute{e}$nez's "House and Studio" (카를로스 히메네즈의 'House and Studio'에 보이는 생장성(生長性)의 지역적 의미에 관한 연구)

  • Ahn, Joon-Suk
    • Journal of the Korean Institute of Rural Architecture
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    • v.14 no.2
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    • pp.11-18
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    • 2012
  • Carlos Jimenez's 'House and Studio' was self-designed to fully function as both a home and workplace. Since its establishment in 1983, the installation has been continuously updated for almost 30 years solely under the guidance of the owner's life occurrences and routine needs. The additions and alterations succeeding the building's erection were executed to incorporate small yet symbolic fragments of the resident's memories and life episodes. The particularity of the 'House and Studio' can be compared with other residential remodeling and expansion projects in regards to certain key aspects. These means of comparison include, but are not limited to, building strictly under the direction of a master plan of development vs. allowing natural adaptations that comply with the resident's needs, rapid development vs. gradual advancement, the ornamenting by exposing showy features vs. the enhancing by addition of modest natural components, sustainability vs. sustenance, systematic room divisions vs. ambiguous spatial organization, possession as a materialized asset vs. preservation as a recollection of memories, and finally the recognition as one example of signature architecture vs. the witnessing of a maturing animated shelter. The given propositions can be further explained with the comprehension of Erich Fromm's theory of the 'Having' mode and 'Being' mode, two mechanisms that categorize the essence of human life. The 'Having' mode is described by the human greed for wealth, power, and influence, whereas the 'Being' mode is comprised of compassion, joy, and productivity. Fromm's thesis applies to the general sense of human life, but the ideas can be narrowed to accommodate the architectural standpoint. In architecture, the 'Having' mode can be translated to be the conspicuous form-oriented and self-contained object. The 'Being' mode, on the other hand, is transposed as the more natural form, incorporating the needs of the owner before commercialization. The growth of Jimenez's 'House and Studio' can be perceived as an architectural suggestion to the overcoming of human indifference caused by fixation on the 'Having' mode.

Current status and outlook on genetic transformation of fruit trees in Korea (과수 형질전환 국내 연구 동향 및 전망)

  • Kim, Jeong-Hee;Song, Kwan-Jeong
    • Journal of Plant Biotechnology
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    • v.37 no.4
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    • pp.408-413
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    • 2010
  • The paper reviewed research status and outlook of genetic transformation in fruit trees in Korea. Genetic transformation has been long considered as an alternative technique overcoming limitation of conventional breeding and conducted since early 1990's. An efficient genetic transformation was established with major cultivars of apple, even in Fuji and Gamhong, and some transgenic apple plants have been transferred into the greenhouse for further analysis of gene expression. A few successes of genetic transformation have been reported and application to a variety of cultivars tried in citrus and kiwifruit. Successful genetic transformation has not been reported in the other fruit trees including grapevine, yet and it is considered being at the level of research. Those factors including replacement of antibiotics as a selective agent, use of transgenic rootstocks and manipulation of gene expression at proper parts and developmental stages have been prerequisites for the rapid commercialization of transgenic fruit plants.

Analysis of Commercial Recycling Technology and Research Trend of Printed Circuit Boards in Korea (국내 인쇄회로기판의 재활용 상용화 기술 및 연구동향 분석)

  • An, HyeLan;Kang, Leeseung;Lee, Chan-Gi
    • Resources Recycling
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    • v.26 no.4
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    • pp.9-18
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    • 2017
  • Recently, the amount of electronic scrap is rapidly increasing due to the rapid growth of the electronics industry. Among the components of electronic scrap, the printed circuit board(PCB) is an important recycling target which includes common metals, precious metals, and rare metals such as gold, silver, copper, tin, nickel and so on. In Korea, however, PCB recycling technologies are mainly commercialized by some major companies, and other process quantities are not accurately counted. According to present situation, several urban mining companies, research institutes, and universities are conducting research on recovery of valuable metals from PCBs and/or reusing them as raw materials that is different from existing commercialization process developed by major companies. In this study, we analyzed not only current status of collection/disposal process and recycling of waste PCBs in Korea but also the trend of recycling technologies in order to help resource circulation from waste PCBs become more active.