• Korean Journal of Pharmacognosy
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• v.20 no.4
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• pp.243-253
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• 1989

Anatomical and physico-chemical properties of some nutrient and tonic crude drugs have been estimated and compared. Resin duct and druse crystal were observed more in Acanthopanax Cortex than in Ginseng Radix. Bast fiber bundle and solitary crystals were abandantly present in Glycyrrhizae Radix. Mucilage crude drugs contained mucilage ducts and bundles of raphides as common components and their arrangements of vascular bundles were different. TLC analysis showed different patterns of saponin, flavonoid, ${\gamma}-aminobutyric$ acid and sitosterols.

• The Journal of Pediatrics of Korean Medicine
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• v.30 no.4
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• pp.111-122
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• 2016

Objective The purpose of this study is to investigate recent clinical studies on the effect of herbal medicine in flat warts in China, and to seek better methods to treat and study for flat warts in Korea. Methods The clinical studies from the CAJ (China Academic Journal) of CNKI (China National Knowledge Infrastructure) by key words '扁平疣' in recent 5 years (From January 2011 to December 2015) were searched. Results 16 articles were selected from 122 clinical studies, and analyzed. The most commonly used herbs were Isatidis Radix (板藍根), Equiseti Hiemalis Herba (木賊), Cyperi Rhizoma (香附子), Carthami Flos (紅花), Glycyrrhizae Radix (甘草) etc., and the articles all showed effectiveness over the control group. Conclusion Based on analyzing the studies, herbal medicine has shown effective in flat wart. This study may be useful not only as clinical data, but also to determine better treatment going forward.

• Korean Journal of Pharmacognosy
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• v.10 no.3
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• pp.112-118
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• 1979

21 herbal drugs registered in K.P. III were tested for contamination of fungi and isolation of aflatoxin producible strains. Initially contaminated fungi were Aspergillus group (41.28%) and Penicillium (47.26%) and the other fungi were contaminated somewhat. The most frequent isolation of Aspergillus group was Cnidii Rhizoma and that of Penicillium was Piperis Fructus nigri. Cnidii Rhizoma was the most contaminated drug and Cassiae Cortex was the least among them. Aspergillus flavus was isolated from 10 samples and Aspergillus parasiticus was detected in Glycyrrhizae Radix, Phellodendri Cortex. Aspergillus ochraceus was isolated from only Scutelariae Radix, and Fusarium nivale was isolated from Cnidii Rhizoma and Torreya Semen. None of Aspergillus and Penicillium was detected in only Coptidis Rhizoma. No strains of Aspergillus flavus and Aspergillus parasiticus isolated from were produced aflatoxin.

• The Journal of Internal Korean Medicine
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• v.15 no.2
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• pp.60-69
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• 1994

The total 46 prescriptions of Ju Dal(酒疸), recorded in all the medical were investigated. 1. The most used prescription of Ju Dal(酒疸) is CHIJADAlHUANGTANG(梔子大黃湯). The nest ones are GALCHULTANG(葛朮湯), GALHWAHAIJEONGTANG(葛花解醒湯), DANGGUIBAICCHULTANG(當歸白朮湯). 2. The total 101 kinds of medicines were adminstered for the prescription of Ju Dal(酒疸). Fructus Aurantii Immaturus(枳實) was prescribed for the most popular medicine and Fructus Gardeniae(梔子), Radix et Rhizoma(大黃), Semen Sojae Praeparatum(豆鼓), Radix Glycyrrhizae(甘草), Herba Artemisiae Scopariae(茵蔯) follows. 3. Li Gi(利氣) mediemes were the most popularly prescribed ones, Chung Youl(淸熱) medicines, Hai Dok(解毒) medicines, Sam Sub Li Su(渗濕利水) medicines follows.

• The Journal of Korean Medicine
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• v.20 no.1 s.37
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• pp.161-171
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• 1999

This study was performed to investigate the effect of complex formula(CKRG) consisting of Panax ginseng Radix rubra Koreana. Ganoderma, Cinnamomi Cortex, Glycyrrhizae Radix and Laminariae Thallus on brain ischemia and injury such as KCN-induced brain injury, forced brain ischemia, pulmonary thrombosis. The results were summarized as follows: 1. CKRG extracts showed a decrease of the duration of KCN-induced coma and showcd an increase in life expectancy. 2. CKRG extracts showed a decrease of neurologic grade in hind limb but did not affect neurologic grades in fore limb. Also. CKRG extracts showed a significant decrease of brain ischemic area and edema in MCA occlusion, 3. CKRG extracts showed a protective effect on pulmonary thrombosis induced by collagen and epinephrine. These data suggested that CKRG extracts could be applied to the protection of brain ischemia and injury.

• The Journal of Pediatrics of Korean Medicine
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• v.33 no.2
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• pp.32-47
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• 2019

Objectives The purpose of this study is to investigate clinical studies on the effectiveness of Traditional Chinese Medicine treatment on growing pains in China, and to seek better methods to treat and study for growing pains in South Korea. Methods The clinical studies from the China Academic Journal (CAJ) in China National Knowledge Infrastructure (CNKI) that were published up to January 2019 were reviewed. The key word used were '生長痛', '發育期痛', '治療', '中?治療', '中藥'. Then, the literature were analyzed in regards to the treatment methods and results. Results Among the 35 searched studies, 1 randomized controlled trials, 16 case series, and 3 case reports were selected and analyzed. In most of the studies, the effectiveness of Traditional Chinese Medicine treatment on growing pains was significantly positive. The most commonly used herbs for oral administration were Glycyrrhizae Radix et Rhizoma (甘草), Achyranthis Bidentatae Radix (牛膝), Paeoniae Radix Alba (白芍藥), Dioscoreae Rhizoma (山藥), Angelicae Gigantis Radix (當歸), Astragali Radix (黃?), Atractylodis Rhizoma Alba (白朮), Poria Sclerotium (茯?) Rehmanniae Radix Preparata (熟地黃), Lycopodii Herba (伸筋草). Other treatment methods such as, external application of herb medicine, massage, acupuncture were also used to treat growing pains. Conclusion Based on the results of the clinical studies from China, the use of chinese medicine for treatment of growing pains has been shown to be effective. Additional clinical studies are needed to confirm these findings.

• The Korea Journal of Herbology
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• v.29 no.3
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• pp.71-78
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• 2014

Objectives : This study evaluates the neuroprotective effects of Sopung-tang, a mixture of Notopterygii Rhizoma, Saposhnikoviae Radix, Angelicae Gigantis Radix, Cnidii Rhizoma, Hoelen, Aurantii Nobilis Pericarpium, Pinelliae Tuber, Linderae Radix, Angelicae Dahuricae Radix, Cyperi Rhizoma, Cinnamomi Ramulus, Asari Radix, Glycyrrhizae Radix on the cerebral infarct combined with hyperlipidemia. Method : The hyperlipidemia was induced by the beef tallow 30% diet for 14 days on Sprague-Dawley rats. The cerebral infarct was induced by the middle cerebral artery occlusion (MCAO) for 2 hours with intraluminal thread method. Then the water extract of Sopung-tang was administered a day for 5 days at 3 hours after the cerebral infarct by MCAO. Effect of Sopung-tang was evaluated with the infarct volume and edema percentage by a TTC-stained brain section, and the expressions of Bax and Bcl-2 in the brain tissue by a immunohistochemical stain method. Results : Sopung-tang reduced the infarct size partly in a TTC-stained brain section of the hyperlipidemic MCAO rats. Sopung-tang reduced the infarct volume of the hyperlipidemic MCAO rats significantly. Sopung-tang reduced the edema percentage of the hyperlipidemic MCAO rats, but not significant statistically. Sopung-tang suppressed the Bax expressions in the cerebral penumbra and caudate putamen of the hyperlipidemic MCAO rats significantly. Sopung-tang upregulated the Bcl-2 expression in the caudate putamen of the hyperlipidemic MCAO rats. Conclusion : These results suggest that Sopung-tang plays an anti-apoptotic neuroprotective effect through the suppression of Bax and up-regulation of Bacl-2 expressions in the brain tissues.

• Journal of Sasang Constitutional Medicine
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• v.22 no.3
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• pp.43-50
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• 2010

1. Objectives: The purpose of this study is to understand the origin, changes and the constructive principles of Hyangsayangyitang (XiangShaYangWeiTang). 2. Methods: Hyangsayangyi-tang and other related prescriptions were analyzed in terms of pathology, based on "Donguibogam(東醫寶鑑)", "Donguisusebowon Chobongwon(東醫壽世保元 草本卷)", "Donguisusebowon Gabobon(東醫壽世保元 甲午本)", "Donguisusebowon Sinchukbon(東醫壽世保元 辛丑本)". 3. Results and Conclusions: (1) The origin of Hyangsayangyi-tang is Hyangsayukgunja-tang from "Gongshin Uigamseo(龔信 醫鑑書"). Hyangsayangyi-tang inherited some of the principles from"Euihangangmok(醫學綱目)" Jeonssiyigong-san's (全氏異功散) application. (2) "Gabobon(甲午本)"'s prescription emphasizes the effect of lossen up by using Pogostemonis Herba(藿香). "Sinchukbon(辛丑本)"'s prescription emphasizes the effect of warm up stomach by using Zingiberis Rhizoma(乾薑). (3) Ginseng Radix(人蔘), Atractlodis Rhizoma White(白朮), Glycyrrhizae Radix(甘草), Paeoniae Radix Alba(白芍藥) support Soeumin's spleen root (脾元), and Zingiberis Rhizoma(乾薑), Myristicae Semen(肉豆蔲) warm up stomach, and Pinelliae Rhizoma(半夏), Citri Pericarpium(陳皮) circulate Qi, Crataegi Fructus(山楂), Amomi Fructus(砂仁), Cyperi Rhizoma(香附子) encourage digestion to maintain descending Yin.

• The Journal of Dong Guk Oriental Medicine
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• v.4
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• pp.211-236
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• 1995

This study was carried out to investigate the effects of Mahwangtang and Gamimahwangtang extract and its constituent herbs on the contractile force of rat tracheal smooth muscle treated with acetylcholine and to elucidate its mechanism. The results of this study were follows ; 1. Mahwangtang and Gamimahwangtang significantly inhibited the contractile response of isolated rat tracheal smooth muscle by acetylcholine, and Gamimahwangtang more significantly effects than Mahwangtang. 2. Gamimahwangtang without Ephedrae Herba significantly inhibited the contractile response of isolated rat tracheal smooth muscle by acetylcholine and less inhibited the contractile force than Gamimahwangtang. 3. Gamimahwangtang without Fritillariae Roylei Bulbus, Platycodi Radix, Cinnamomi Ramulus, significantly inhibited the contractile response of isolated rat tracheal smooth muscle by acetylcholine and less inhibited the contractile force than Gamimahwangtang. 4. Gamimahwangtang without Armeniacae Amarum Semen, Glycyrrhizae Radix significantly inhibited the contractile response of isolated rat tracheal smooth muscle by acetylcholine and its difference did not to the Gamimahwangtang. 5. Gamimahwangtang without Ginseng Radix significantly inhibited the contractile response of isolated rat tracheal smooth muscle by acetylcholine and more significantly effects than Gamimahwangtang.

• The Journal of Pediatrics of Korean Medicine
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• v.31 no.1
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• pp.1-11
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• 2017

Objectives The purpose of this study is to investigate commonly-used-pattern-identifications and to understand herbal medicine treatment for psoriasis based on recent clinical studies. Methods Keyword 'psoriasis' was used to search articles in National Digital Science Library (NDSL), Korean Traditional Knowledge Portal (KTKP), Oriental Medicine Advanced Searching Integrated System (OASIS) and Research Information Sharing Service (RISS). 19 relevant articles were reported between 2006 - 2016, and were obtained and reviewed. Results Among the 19 articles, the most commonly-used-pattern-identifications were 'blood heat pattern'. 'Gunsun-bang', 'Bangpungtongsungsan-gami'. Also, based on the search results, 'Yangdokbaekho-tang' were more frequently prescribed than other herbal medicines, and ingredients such as, Glycyrrhizae Radix (甘草), Saposhnikoviae Radix (防風) and Rehmanniae Radix (生地黃) were used repeatedly in those prescriptions. Conclusions This study showed what pattern identifications there are, and what herbal medicines are often used in clinical treatments. Developing new form of herbal medicines are also going to be possible with further research.