• Title/Summary/Keyword: Radiology science department

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Treatment Outcomes of Percutaneous Radiofrequency Ablation for Hepatocellular Carcinomas: Effects of the Electrode Type and Placement Method

  • Jiyeon Park;Min Woo Lee;Soo Hyun Ahn;Seungchul Han;Ji Hye Min;Dong Ik Cha;Kyoung Doo Song;Tae Wook Kang;Hyunchul Rhim
    • Korean Journal of Radiology
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    • v.24 no.8
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    • pp.761-771
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    • 2023
  • Objective: To investigate the association among the electrode placement method, electrode type, and local tumor progression (LTP) following percutaneous radiofrequency ablation (RFA) for small hepatocellular carcinomas (HCCs) and to assess the risk factors for LTP. Materials and Methods: In this retrospective study, we enrolled 211 patients, including 150 males and 61 females, who had undergone ultrasound-guided RFA for a single HCC < 3 cm. Patients were divided into four combination groups of the electrode type and placement method: 1) tumor-puncturing with an internally cooled tip (ICT), 2) tumor-puncturing with an internally cooled wet tip (ICWT), 3) no-touch with ICT, and 4) no-touch with ICWT. Univariable and multivariable Cox proportional-hazards regression analyses were performed to evaluate the risk factors for LTP. The major RFA-related complications were assessed. Results: Overall, 83, 34, 80, and 14 patients were included in the ICT, ICWT, no-touch with ICT, and no-touch with ICWT groups, respectively. The cumulative LTP rates differed significantly among the four groups. Compared to tumor puncturing with ICT, tumor puncturing with ICWT was associated with a lower LTP risk (adjusted hazard ratio [aHR] = 0.11, 95% confidence interval [CI] = 0-0.88, P = 0.034). However, the cumulative LTP rate did not differ significantly between tumor-puncturing with ICT and no-touch RFA with ICT (aHR = 0.34, 95% CI = 0.03-1.62, P = 0.188) or ICWT (aHR = 0.28, 95% CI = 0-2.28, P = 0.294). An insufficient ablative margin was a risk factor for LTP (aHR = 6.13, 95% CI = 1.41-22.49, P = 0.019). The major complication rates were 1.2%, 0%, 2.5%, and 21.4% in the ICT, ICWT, no-touch with ICT, and no-touch with ICWT groups, respectively. Conclusion: ICWT was associated with a lower LTP rate compared to ICT when performing tumor-puncturing RFA. An insufficient ablation margin was a risk factor for LTP.

No-Touch Radiofrequency Ablation for Early Hepatocellular Carcinoma: 2023 Korean Society of Image-Guided Tumor Ablation Guidelines

  • Seungchul Han;Min Woo Lee;Young Joon Lee;Hyun Pyo Hong;Dong Ho Lee;Jeong Min Lee
    • Korean Journal of Radiology
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    • v.24 no.8
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    • pp.719-728
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    • 2023
  • Radiofrequency ablation (RFA) has been widely used to manage hepatocellular carcinomas (HCCs) equal to or smaller than 3 cm. No-touch RFA has gained attention and has recently been implemented in local ablation therapy for HCCs, despite its technical complexity, as it provides improved local tumor control compared to conventional tumor-puncturing RFA. This article presents the practice guidelines for performing no-touch RFA for HCCs, which have been endorsed by the Korean Society of Image-Guided Tumor Ablation (KSITA). The guidelines are primarily designed to assist interventional oncologists and address the limitations of conventional tumor-puncturing RFA with describing the fundamental principles, various energy delivery methods, and clinical outcomes of no-touch RFA. The clinical outcomes include technical feasibility, local tumor progression rates, survival outcomes, and potential complications.

Reference dose levels for dental periapical radiography in Chonnam Province (전남 지방에서 치근단방사선사진의 참고 선량 수준)

  • Han, Mi-Ra;Kang, Byung-Cheol;Lee, Jae-Seo;Yoon, Suk-Ja;Kim, Young-Hee
    • Imaging Science in Dentistry
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    • v.39 no.4
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    • pp.195-198
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    • 2009
  • Purpose : To establish reference doses of periapical radiography in Chonnam Province, Korea. Materials and Methods : The target-skin distances were measured for dental patient's 1235 exposures including 345 mandibular molar areas. Each periapical radiation exposure was simulated with exactly the same patients exposure parameters and the simulated radiation doses were measured utilizing Mult-O-Meter (Unfors Instruments, Billadal, Sweden). The measurements were done in 44 dental clinics with 49 dental x-ray sets in Chonnam Province for one or two weeks at each dental clinic during year 2006. Results : The third quartile patient surface doses were 2.8 mGy for overall periapical exposures and 3.2 mGy for periapical mandibular molar exposures. Conclusion : The third quartile patient surface doses in Chonnam Province can be used as a guide to accepted clinical practice to reduce patient radiation exposure for the surveyed reference doses were below the recommended dental periapical radiography dose of 7 mGy by IAEA.

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T1 Map-Based Radiomics for Prediction of Left Ventricular Reverse Remodeling in Patients With Nonischemic Dilated Cardiomyopathy

  • Suyon Chang;Kyunghwa Han;Yonghan Kwon;Lina Kim;Seunghyun Hwang;Hwiyoung Kim;Byoung Wook Choi
    • Korean Journal of Radiology
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    • v.24 no.5
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    • pp.395-405
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    • 2023
  • Objective: This study aimed to develop and validate models using radiomics features on a native T1 map from cardiac magnetic resonance (CMR) to predict left ventricular reverse remodeling (LVRR) in patients with nonischemic dilated cardiomyopathy (NIDCM). Materials and Methods: Data from 274 patients with NIDCM who underwent CMR imaging with T1 mapping at Severance Hospital between April 2012 and December 2018 were retrospectively reviewed. Radiomic features were extracted from the native T1 maps. LVRR was determined using echocardiography performed ≥ 180 days after the CMR. The radiomics score was generated using the least absolute shrinkage and selection operator logistic regression models. Clinical, clinical + late gadolinium enhancement (LGE), clinical + radiomics, and clinical + LGE + radiomics models were built using a logistic regression method to predict LVRR. For internal validation of the result, bootstrap validation with 1000 resampling iterations was performed, and the optimism-corrected area under the receiver operating characteristic curve (AUC) with 95% confidence interval (CI) was computed. Model performance was compared using AUC with the DeLong test and bootstrap. Results: Among 274 patients, 123 (44.9%) were classified as LVRR-positive and 151 (55.1%) as LVRR-negative. The optimism-corrected AUC of the radiomics model in internal validation with bootstrapping was 0.753 (95% CI, 0.698-0.813). The clinical + radiomics model revealed a higher optimism-corrected AUC than that of the clinical + LGE model (0.794 vs. 0.716; difference, 0.078 [99% CI, 0.003-0.151]). The clinical + LGE + radiomics model significantly improved the prediction of LVRR compared with the clinical + LGE model (optimism-corrected AUC of 0.811 vs. 0.716; difference, 0.095 [99% CI, 0.022-0.139]). Conclusion: The radiomic characteristics extracted from a non-enhanced T1 map may improve the prediction of LVRR and offer added value over traditional LGE in patients with NIDCM. Additional external validation research is required.

Application of Dual-Energy Spectral Computed Tomography to Thoracic Oncology Imaging

  • Cherry Kim;Wooil Kim;Sung-Joon Park;Young Hen Lee;Sung Ho Hwang;Hwan Seok Yong;Yu-Whan Oh;Eun-Young Kang;Ki Yeol Lee
    • Korean Journal of Radiology
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    • v.21 no.7
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    • pp.838-850
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    • 2020
  • Computed tomography (CT) is an important imaging modality in evaluating thoracic malignancies. The clinical utility of dual-energy spectral computed tomography (DESCT) has recently been realized. DESCT allows for virtual monoenergetic or monochromatic imaging, virtual non-contrast or unenhanced imaging, iodine concentration measurement, and effective atomic number (Zeff map). The application of information gained using this technique in the field of thoracic oncology is important, and therefore many studies have been conducted to explore the use of DESCT in the evaluation and management of thoracic malignancies. Here we summarize and review recent DESCT studies on clinical applications related to thoracic oncology.