• Clinical and Experimental Pediatrics
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• v.57 no.11
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• pp.500-504
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• 2014

Kaposiform hemangioendothelioma (KHE) is a rare, locally aggressive vascular tumor of intermediate malignancy with resemblance to Kaposi sarcoma. It occurs predominantly in pediatric age groups as a cutaneous lesion with focal infiltration into the adjacent soft tissue and bone. Although visceral involvement is very uncommon, several cases with bone, retroperitoneal, or mediastinal involvement have been described. KHE has been reported to occasionally occur in unusual sites such as the thymus, tonsils, larynx, paranasal sinuses, deltoid muscle, spleen, uterine cervix, thoracic spine, and even the breast. Multifocal KHE is an extremely rare entity with few reports available in the literature, none of which describes pulmonary involvement. Herein, we report a unique case of multifocal KHE in a 13-year-old boy presenting with a huge soft tissue mass in the upper extremity complicated by bilateral pulmonary nodules that developed into large, necrotic tumor masses.

• Journal of the Korean Society of Radiology
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• v.13 no.7
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• pp.917-924
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• 2019

The passive scattering system nozzle of the proton therapy accelerator was simulated to evaluate the neutrons generated by each component in each nozzle by energy. The Monte Carlo N-Particle code was used to implement spread out Bragg peak with proton energy 220 MeV, reach 20 cm, and 6 cm length used in the treatment environment. Among the proton accelerator components, neutrons were the highest in scatterers, and the neutron flux decreased as it moved away from the central flux of the proton. This study can be used as a basic data for the evaluation of the radiation necessary for the maintenance and dismantling of proton accelerators.

• Journal of the Korean Society of Radiology
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• v.11 no.4
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• pp.241-246
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• 2017

The existing fractal compression method is effective in generating an artificial shape by approximating its partial regions to a domain block by re-dividing the whole image into a domain region and dividing it into several domain blocks, but it is difficult to implement a computer. In this study, it is difficult to approximate a complex block such as a large-sized block and an affine transformation because a large amount of calculation is required in searching for a combination of similar blocks through a transformation, so a large amount of coding time is required.

• Journal of the Korean Society of Radiology
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• v.14 no.5
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• pp.523-528
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• 2020

The application of breast cancer, which has the highest incidence in females among cancer that is the number one cause of death for dogs, was to be evaluated the absorbed dose during brachytherapy using simulation. MCNPX program was used for simulation, and a small size canine phantom was produced to measure absorbed dose. The results of the absorbed dose was the highest at ¹⁹²Ir to 1.02E-12 Gy/# for tumors, and the same tendency was shown for internal and external absorbed dose. Therefore, the selection of appropriate sources for dog breast cancer should be considered in brachytherapy, taking into account dog breeds and exposures.

• Journal of the Korean Society of Radiology
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• v.13 no.2
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• pp.241-246
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• 2019

Among the 4th Industrial Revolution technologies, evaluated bolus applicability through dose assesment according to the materials of 3D printing technology. Dose assesment was using MCNPX which was applied Monte Carlo method and 3D print materials were ABS, PC and PLA. Thus, the thickness with the same effect as the bolus 10 mm was found to be ABS 10 mm, PC 9 mm and PLA 9 mm for the 6 MeV electron. For 6 MV X-ray, ABS 11 mm, PC 10 mm and PLA 9 mm were shown. This study showed that tissue equivalent materials made from 3D printer materials can replace bolus.

• Journal of Radiation Industry
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• v.17 no.3
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• pp.233-238
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• 2023

This study was conducted to confirm the safety of the operator's radiation exposure in the micro PET-CT image acquisition experiment using the ¹⁸F-FDG. The usage of ¹⁸F-FDG and the exposure dose of handlers were measured at University B in Metropolitan City A, which uses ¹⁸F-FDG for micro PET-CT image acquisition. As a result of the measurement, the exposure dose is far below the effective dose limit of radiation workers, 50 mSv per year, and the equivalent dose limit of 500 mSv per year for hands, feet, and skin. has been measured Since these exposure doses can be further increased according to the number of times of use of ¹⁸F-FDG, it is judged that the exposure dose compared to the handling amount of ¹⁸F-FDG shown in this study can be used as reference data. In addition, as changed environments such as the use of materials other than unopened RI are occurring in education and research environments, such as the use of ¹⁸F-FDG at University B, radiation exposure with more interest in safety management by checking the factors of radiation exposure of the handler concerned We will always do our best to reduce it.

• Journal of Radiation Protection and Research
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• v.26 no.4
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• pp.347-356
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• 2001

Guarana, a tropical plant is found in powdered for in health food and is very popular soft drink in Brazil as an energy feaster with its high caffeine contents. We examined its radioprotection effects during organogenesis stages of ICR mice by malformations rate and cellular lead 8 the embryo by radiation and analyzed the mechanism of the radioprotection effects in the fetal of ICR mice. The results of this study showed that Guarana reduced clearly the embryonic death rate and teratogenesis rate by radiation. Its radioprotection effect inject be related with its radioprotection effect might be related with its antioxidant effect or free radical scavenger. We need to exposure the Guarana as a potential radioprotection agent. Therefore, we investigated about radiation effects by Guarana using to mice experiments in this paper.

• Proceedings of the Optical Society of Korea Conference
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• 2000.08a
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• pp.118-120
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• 2000

Currently, x-ray is mostly used for the diagnosis of dental cavity and osteoporosis. The osteoporosis is broadly defined as a decrease in the amount of bone mass per unit volume of the bone. Clinically the manifestation of low bone mass presents a clinical problem to the general population as an increase in fracture risk and especially in aging population[1]. Although the amount of the irradiated x-ray to the human body for the clinical diagnosis is relatively small, the exposition of the x-ray to the human body should be minimized as much as possible, since the x-ray is an ionizing radiation. To investigate other possible systems replacing X-ray, ultrasonic imaging and MRI(Magneto-Resonance-Imaging) systems were studied. Unfortunately, an effective and safe diagnosis tool for detecting the dental cavity and the osteoporosis is currently lacking. (omitted)

• Radiation Oncology Journal
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• v.17 no.3
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• pp.261-267
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• 1999

Purpose : In FSRT (Fractionated stereotactic radiotherapy) planning, we studied the usefulness between multiple arc FSRT and conformal FSRT by comparing tumor shape and DVH (dose volume histogram). Materials and Methods In Chungnam Univ. hospital, we had treated the sixteen patients with FSRT from Aug. 1997 to Dec. 1998. In choosing multiple arc FSRT or conformal FSRT, we had considered If (irregular factor) after calculating tumor volume and surface area. We had considered multiple arc FSRT if tumor shape was similar to sphere or the value of If was less than 1.25, conformal FSRT if tumor shape was very irregular or If was more than 1.3. For evaluation of treatment planning, we had considered the appropriate DVH for tumor volume and for critical organs. Results : The errors between reference point and the coordinates point on AP, Lat radiography were less than 1 mm before treatment. We had planned $3\~$5 arcs for multiple arc FSRT, $5\~6$ports for conformal FSRT. The mean dose distribution of tumor volume of cumulative DVH between multiple arc FSRT and conformal FSRT was 90.6, 85%, respectively. The dose of critical organs irradiated was less than $5\%$ maximum dose of cumulative DVH. Conclusion : We had obtained the similar value between multiple arc FSRT and conformal FSRT, so that we had appropriate treatment planning of FSRT for multiple arc FSRT and conformal FSRT according to tumor shape and size.

• Animal cells and systems
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• v.15 no.2
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• pp.139-146
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• 2011

Secretory leukocyte protease inhibitor (SLPI) plays an important role in promoting the invasion and metastasis of a range of cancer cells. However, there are no reports of the expression and function of SLPI in oral carcinoma cells. In this study, the oral carcinoma cell line KB was used to determine whether SLPI affects the proliferation, migration and invasion of oral carcinoma cells. RT-PCR and Western blotting revealed high levels of endogenous SLPI expression in KB cells as well as a strong increase in SLPI secretion after wounding compared to immortalized normal oral keratinocytes (INOK). The wound healing assay revealed more migration of KB cells than INOK cells, and the SLPI treatment increased the migration of KB cells. KB cell proliferation was increased significantly by the SLPI protein but decreased by SLPI-siRNA. SLPI strongly increased the migration and invasion of KB cells. On the other hand, SLPI-siRNA decreased the migration and invasion of KB cells. This suggests that SLPI plays an important role in the metastasis of oral carcinoma cells.