• 제목/요약/키워드: Radiation technology

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장기 중선량률 감마선 피폭에 의한 마우스의 생존율 및 생물학적 영향 평가 (Survival Rate and Biological Effect of Chronic Medium-Dose-Rate Gamma Radiation Exposed to Mice)

  • 김재경;진영배;오수미;이윤종;성낙윤;송범석;박종흠;변의백;이주운;김재훈
    • 방사선산업학회지
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    • 제7권2_3호
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    • pp.155-159
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    • 2013
  • Late effects of chronic exposure to gamma radiation are potential hazards to worker in radiation facilities as well as to the general public. Recently, chronic gamma radiation exposure effects have become a serious concern. Using a total of 60 mice, we studied the biological effects of medium-dose chronic exposure to gamma radiation. Sixty female 6-week-old specific pathogen free Balb/c mice were randomly divided into six groups (five groups irradiated and one non-irradiated control group). Irradiation was carried out for 7 days using gamma rays at dose rates of 119.65, 238.10, 357.14, 476.19 and $595.24mGy\;h^{-1}$ with total doses 20, 40, 60, 80 and 100 Gy. After irradiation, we determined survival rate of gamma radiation exposed mice during 1 week and 476.19 and $595.24mGy\;h^{-1}$ exposed group mice showed less 10% of survival rate. Otherwise, 119.65, 238.10 and $357.14mGy\;h^{-1}$ exposed group mice were survived each 100%, 80% and 70%. Half of survived mice after 1 week are immediately sacrifice and counted body and spleen weights. Compared with control non-irradiated group, total body weights and spleen weights isolated from 119.65, 238.10 and 357.14 irradiated group mice showed significant decreased. However, no significant alteration was observed between 119.65, 238.10 and $357.14mGy\;h^{-1}$ irradiated group. Overall, our results show for the first time that medium-dose chronic gamma radiation has the potential to stimulation of biological effects.

감마선 조사 냉동비빔밥의 미생물 및 관능적 품질특성 (Microbiological and Sensory Characteristics of Gamma-irradiated Frozen Bibimbap)

  • 박재남;송범석;윤영민;최수정;박종흠;김재경;변의백;이주운;한인준;손희숙;김재훈
    • 방사선산업학회지
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    • 제7권2_3호
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    • pp.93-99
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    • 2013
  • This study was conducted to evaluate the effect of gamma irradiation on the microbiological and sensory characteristics of frozen Bibimbap. Frozen Bibimbap vegetables were contaminated by microbial levels of $2.70{\sim}6.67log\;CFU\;g^{-1}$ in total aerobic bacteria. Frozen Bibimbap was contaminated by microbial levels of $4.8log\;CFU\;g^{-1}$ in total aerobic bacteria, but microorganisms in gamma-irradiated samples at above 25 kGy were not found at detection limit less then $1log\;CFUg^{-1}$. Sensory characteristics of the gamma-irradiated Bibimbap were decreased depending upon the irradiation dose, and sensory scores of the samples irradiated with doses higher than 10 kGy were significantly decreased. Therefore, the application of combination of the various food processing technology should be considered for the sterilization of Bibimbap, without any deterioration of quality occurred by high dose irradiation.

Autonomous exploration for radioactive sources localization based on radiation field reconstruction

  • Xulin Hu;Junling Wang;Jianwen Huo;Ying Zhou;Yunlei Guo;Li Hu
    • Nuclear Engineering and Technology
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    • 제56권4호
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    • pp.1153-1164
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    • 2024
  • In recent years, unmanned ground vehicles (UGVs) have been used to search for lost or stolen radioactive sources to avoid radiation exposure for operators. To achieve autonomous localization of radioactive sources, the UGVs must have the ability to automatically determine the next radiation measurement location instead of following a predefined path. Also, the radiation field of radioactive sources has to be reconstructed or inverted utilizing discrete measurements to obtain the radiation intensity distribution in the area of interest. In this study, we propose an effective source localization framework and method, in which UGVs are able to autonomously explore in the radiation area to determine the location of radioactive sources through an iterative process: path planning, radiation field reconstruction and estimation of source location. In the search process, the next radiation measurement point of the UGVs is fully predicted by the design path planning algorithm. After obtaining the measurement points and their radiation measurements, the radiation field of radioactive sources is reconstructed by the Gaussian process regression (GPR) model based on machine learning method. Based on the reconstructed radiation field, the locations of radioactive sources can be determined by the peak analysis method. The proposed method is verified through extensive simulation experiments, and the real source localization experiment on a Cs-137 point source shows that the proposed method can accurately locate the radioactive source with an error of approximately 0.30 m. The experimental results reveal the important practicality of our proposed method for source autonomous localization tasks.

장기 중선량률의 감마선 피폭 기간에 따른 실험동물의 생물학적 영향 연구 (Biological Effects of Different Chronic Medium-Dose-Rate Gamma Radiation Period Exposed on Mice)

  • 김재경;진영배;오수미;이윤종;성낙윤;송범석;박종흠;변의백;이주운;김재훈
    • 방사선산업학회지
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    • 제7권2_3호
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    • pp.135-139
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    • 2013
  • Recently, chronic gamma radiation exposure on biological effects in middle dose-rates have become a serious concern. We investigated the biological effects of middle dose chronic exposure to gamma ray. Fifty male 6-week-old specific free Balb/c mice were randomly divided into five groups (four groups irradiated and one non-irradiated control group). Gamma radiation exposed in Gamma phytotron on Advanced Radiation Technology Institute (Jeongeup, Korea). Irradiation was carried out for 1 or 2 weeks using gamma rays at dose rates of 45 and $50mGy\;h^{-1}$ with total doses 7.56 Gy ($45mGy\;h^{-1}$, 1 week), 8.4 Gy ($50mGy\;h^{-1}$, 1 week), 15.12 Gy ($45mGy\;h^{-1}$, 2 weeks) and 16.8 Gy ($50mGy\;h^{-1}$, 2 weeks). After irradiation, immediately we sacrificed and counted body and organ weights. Moreover we counted spleen cell numbers. Compared with control non-irradiated group, all irradiated groups of body and spleen weights showed significant decreased. However, no significant alteration was observed between same irradiated period groups. In spleen cell numbers, reduced compared to the control group. However, significant alteration was observed between same irradiated period groups ($45mGy\;h^{-1}$, $50mGy\;h^{-1}$). These results demonstrated biological effects according to the radiation dose rate and irradiated period.

Preparation of Poly (Vinyl Alcohol) Nanofibers Containing Silver Nanoparticles by Gamma-ray Irradiation

  • Kim, Yun-Hye;Shin, Junwha;Youn, Min-Ho;An, Sung-Jun;Lim, Youn-Mook;Gwon, Hui-Jeong;Nho, Young-Chang
    • 방사선산업학회지
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    • 제2권3호
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    • pp.129-133
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    • 2008
  • PVA nanofibers containing silver nanoparticles were prepared by two methods. The first method was electrospinning of irradiated solution. The prepared $PVA/AgNO_3$ solution was irradiated by gamma-rays. And then the irradiated solution was electrospun. The second method was irradiation of electrospun nanofibers. Nanofibers prepared by electrospinning of unirradiated $PVA/AgNO_3$ solution. The morphology of the nanofibers was observed with a SEM, TEM. When the irradiated $PVA/AgNO_3$ solution were electrospun, the average size of the Ag nanoparticles was increased, but their number was decreased.

마이크로웨이브 플라즈마 처리를 통한 섬광체 패널 기판의 접촉가 특성변화 (Characteristics of the Contact Angle Using the Microwave Plasma Treatment on Scintillator Panel Substrates)

  • 김병욱;김영주;유철우;최병정;권영만;이영춘;김명수;조규성
    • 방사선산업학회지
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    • 제8권1호
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    • pp.43-47
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    • 2014
  • By measuring decrease change of the contact angle after microwave plasma treatment on the glass and Al as a scintillator panel sample substrate, the adhesive performance of scintillator panel can be expected to improve. Also resolution and sensitivity of scintillator panel after microwave plasma treatment can be expected to maintain highly.

A novel radiation-dependence model of InP HBTs including gamma radiation effects

  • Jincan Zhang;Haiyi Cai;Na Li;Liwen Zhang;Min Liu;Shi Yang
    • Nuclear Engineering and Technology
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    • 제55권11호
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    • pp.4238-4245
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    • 2023
  • In order to predict the lifetime of InP Heterojunction Bipolar Transistor (HBT) devices and related circuits in the space radiation environment, a novel model including gamma radiation effects is proposed in this paper. Based on the analysis of radiation-induced device degradation effects including both DC and AC characteristics, a set of empirical expressions describing the device degradation trend are presented and incorporated into the Keysight model. To validate the effective of the proposed model, a series of radiation experiments are performed. The correctness of the novel model is validated by comparing experimental and simulated results before and after radiation.

방사선 유도 돌연변이체 블랙베리 발효음료의 알코올 대사 및 숙취 억제 효과 (Effect of Fermented Blackberry Drinks Formed from Radiation-induced Mutant on Alcohol Metabolism and Hangover in Rats)

  • 조병옥;소양강;이창욱;조정근;우현심;진창현;정일윤
    • 방사선산업학회지
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    • 제7권1호
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    • pp.75-80
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    • 2013
  • This study was designed to elucidate the effect of fermented blackberry drinks (BD) on alcohol metabolism and hangover in alcohol-treated rats. We showed that the administration of BD increased the activity of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in alcohol-treated rats. Moreover, the administration of BD reduced the serum alcohol and acetaldehyde concentrations in alcohol-treated rats. Furthermore, the administration of BD attenuated the levels of serum aspartate aminotransferase and alanine aminotransferase in alcohol-treated rats. Taken together, these results suggest that BD plays an important role in alcohol metabolism and liver function by reducing blood alcohol and acetaldehyde through the activation of ADH and ALDH in alcohol-treated rats and could be used as a functional anti-hangover drinks.

No Late Effect of Ionizing Radiation on the Aging-Related Oxidative Changes in the Mouse Brain

  • Jang, Beom-Su;Kim, Seolwha;Jung, Uhee;Jo, Sung-Kee
    • 방사선산업학회지
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    • 제4권3호
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    • pp.203-207
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    • 2010
  • Radiation-induced late injury to normal tissue is a primary area of radiation biology research. The present study was undertaken to investigate whether the late effect of the ionizing radiation appears as an age-related oxidative status in the brain. Three groups of 4-month old C57BL/6 mice that were exposed to $^{137}Cs$ ${\gamma}-rays$ at a single dose (5 Gy) or fractionated doses ($1Gy{\times}5times$, or $0.2Gy{\times}25times$) at 2 months old were investigated for the oxidative status of their brains with both young (2-month) and old (24-month) mice. A significant (p<0.05) decrease in superoxide dismutase (SOD) activity was observed in old mice brains compared with that of the young mice. malondialdehyde (MDA) content was significantly (p<0.05) increased in the old mice brain. However, any significant difference in SOD activity and MDA contents of the irradiated brain was not observed compared to age-matched control group mice. SOD activity and MDA content were observed within good parameters of brain aging and there were no late effects on the age-related oxidative level in the ${\gamma}-ray$ irradiated mice brains.

Proteome Analysis of Escherichia coli after High-dose Radiation

  • Lim, Sangyong;Lee, Misong;Joe, Minho;Song, Hyunpa;Kim, Dongho
    • 방사선산업학회지
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    • 제5권1호
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    • pp.1-5
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    • 2011
  • Since proteomics can be employed to compare changes in the expression levels of many proteins under particular genetic and environmental conditions, using mass spectrometry to establish radiation stimulon, we performed two-dimensional gel electrophoresis and identified E. coli proteins whose expressions are affected by high dose of ionizing radiation. After exposure to 3 kGy, it was found that 6 proteins involved in carbon and energy metabolism were reduced. Although 4 of 7 protein spots showing a significant increase in expression level were neither identified nor classified, uridine phosphorylase (Udp), superoxide dismutase (SodB), and thioredoxin-dependent thiol peroxidase (Bcp) were proven to be up-regulated after irradiation. This suggests that E. coli subjected to high doses of radiation (3 kGy) may operate a defense system that is able to detoxify reactive oxygen species and stimulate the salvage pathway of nucleotide synthesis to replenish damaged DNA.