Journal of Radiation Industry (방사선산업학회지)

Korean Society of Radiation Industry (한국방사선산업학회)
권호 표지

Effect of Fermented Blackberry Drinks Formed from Radiation-induced Mutant on Alcohol Metabolism and Hangover in Rats

방사선 유도 돌연변이체 블랙베리 발효음료의 알코올 대사 및 숙취 억제 효과

  • Cho, Byoung Ok (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • So, Yangkang (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Lee, Chang Wook (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Cho, Jung Keun (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Woo, Hyun Sim (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Jin, Chang Hyun (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Jeong, Il Yun (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute)
  • 조병옥 (한국원자력연구원 첨단방사선연구소) ;
  • 소양강 (한국원자력연구원 첨단방사선연구소) ;
  • 이창욱 (한국원자력연구원 첨단방사선연구소) ;
  • 조정근 (한국원자력연구원 첨단방사선연구소) ;
  • 우현심 (한국원자력연구원 첨단방사선연구소) ;
  • 진창현 (한국원자력연구원 첨단방사선연구소) ;
  • 정일윤 (한국원자력연구원 첨단방사선연구소)
  • Received : 2013.07.10
  • Accepted : 2013.08.01
  • Published : 2013.03.31

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Abstract

This study was designed to elucidate the effect of fermented blackberry drinks (BD) on alcohol metabolism and hangover in alcohol-treated rats. We showed that the administration of BD increased the activity of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in alcohol-treated rats. Moreover, the administration of BD reduced the serum alcohol and acetaldehyde concentrations in alcohol-treated rats. Furthermore, the administration of BD attenuated the levels of serum aspartate aminotransferase and alanine aminotransferase in alcohol-treated rats. Taken together, these results suggest that BD plays an important role in alcohol metabolism and liver function by reducing blood alcohol and acetaldehyde through the activation of ADH and ALDH in alcohol-treated rats and could be used as a functional anti-hangover drinks.

Keywords

Acknowledgement

Supported by : 미래창조과학부