• Title/Summary/Keyword: Radiation level

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Redistribution of Lactate Dehydrogenase Isozymes and Morphology of Tissues in Mus musculus after Irradiation (방사선 조사 후 생쥐(Mus musculus)조직의 형태와 젖산탈수소효소 동위효소의 재분포)

  • 박현도;염정주
    • Korean Journal of Environmental Biology
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    • v.17 no.3
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    • pp.263-270
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    • 1999
  • In order to identify the morphological changes of tissues in mouse after irradiation. We have observed the redistribution of LDH isozymes and the morphological changes of skeletal muscle, heart, kidney, liver and testis in mouse according to variation amount with the time after the 1 Gray and 3 Gray irradiation each. As a result of H-E (hematoxylin-eosin) stain, the apoptotic bodies were more easily observed in the liver than the other tissues and the quantity of the apoptotic bodies was proportionated to radiation amount. The number of apoptotic bodies was shown the highest at 1 day in most tissues and at 7 day in testis after irradiation. TUNEL (terminal deoxyribonucleodtidyl transferase-mediated dUTP-digoxigenin nick end labeling) staining was shown the same results as H-E staining. After the irradiation, the protein content was reduced in tissues except kidney. And protein content was reduced in all tissues at the initial period of 2 hours after 3 Gy irradiation. But it increased at 7 days after irradiation. LDH (EC 1.1.1.27, lactate dehydrogenase) activity was increased mostly in tissues at the early stage after 1 Gy irradiation. The maximum activity was detected earlier stage after 1 Gy irradiation than 3 Gy irradiation. The activity of LDH $A_4$ isozyme was decreased in the skeletal muscle, heart, kidney, and testis. The activity of $B_4$ and $A_2$$B_2$ sozyme was increased in the skeletal muscle and heart, and the activity of heterotetramer isozyme was increased in kidney The activity of $A_4$ isozyme in liver was detected high level and the activity of isozyme including subunit C elevated in testis. Therefore, LDH isozyme seems to play a role of lactate oxidase in most tissues except liver after irradiation. These data support that LDH isozyme is predomintly involved in the aerobic metabolism.

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Favorable Irrigation Timing with Timer and Fruiting Position Focused on the Fruit Quality and Harvesting Time in Perlite Culture of Muskmelon (멜론의 펄라이트 재배시 타이머 제어에 의한 급액 시간과 착과절위가 과실의 품질과 수확시기에 미치는 영향)

  • Kim, H. J.;Kim, Y. S.
    • Journal of Bio-Environment Control
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    • v.11 no.4
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    • pp.157-162
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    • 2002
  • The efficient timer-controlled irrigation and the favorable fruiting position were investigated far highly quality melon fruits from Feb.18 to July Si 1999. The nutrient solution was supplied either at every hour from 6:00 to 18:00 (T-1) or at 6:00, 8:00, 10:00, 11:00, 12:00, 12:30, 13:00, 13:30, 14:00, 14:30, IS:00,16:00, and 17:00 (T-2). A fruit was set at the first node of the fruit bearing branch from the 10, 12, or 13th node of the main stem. Pot weight was maintained at almost n constant level, regardless of the daily integrated solar radiation in T-2. Soluble solids content (SSC) and fresh weight of fruit were not significantly different among the irrigation treatments at each harvesting time. At the first harvest, SSC and fresh weight of fruit were not significantly different between the fruiting positions within the irrigation treatment. At the second harvest, SSC was higher in T-2 than T-1. The SSC was low in the fruit of the loth node in T-1, while it was not significantly different between fruiting positions in T-2. Fruit fresh weight was the highest at the 12 and 13th nodes in T-1, and the 13th node in T-2. Fresh and dry weights of leaf except petiole, regardless of harvesting time, increased as the node position was higher, The higher the fruiting position was, the lower the leaf weight was. Therefore, it is recommended to irrigate more frequently during the mid-noon. Fruits can be harvested earlier at the lower nodes in the spring crop production.

Validation of a New Design of Tellurium Dioxide-Irradiated Target

  • Fllaoui, Aziz;Ghamad, Younes;Zoubir, Brahim;Ayaz, Zinel Abidine;Morabiti, Aissam El;Amayoud, Hafid;Chakir, El Mahjoub
    • Nuclear Engineering and Technology
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    • v.48 no.5
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    • pp.1273-1279
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    • 2016
  • Production of iodine-131 by neutron activation of tellurium in tellurium dioxide ($TeO_2$) material requires a target that meets the safety requirements. In a radiopharmaceutical production unit, a new lid for a can was designed, which permits tight sealing of the target by using tungsten inert gaswelding. The leakage rate of all prepared targets was assessed using a helium mass spectrometer. The accepted leakage rate is ${\leq}10^{-4}mbr.L/s$, according to the approved safety report related to iodine-131 production in the TRIGA Mark II research reactor (TRIGA: Training, Research, Isotopes, General Atomics). To confirm the resistance of the new design to the irradiation conditions in the TRIGA Mark II research reactor's central thimble, a study of heat effect on the sealed targets for 7 hours in an oven was conducted and the leakage rates were evaluated. The results show that the tightness of the targets is ensured up to $600^{\circ}C$ with the appearance of deformations on lids beyond $450^{\circ}C$. The study of heat transfer through the target was conducted by adopting a one-dimensional approximation, under consideration of the three transfer modes-convection, conduction, and radiation. The quantities of heat generated by gamma and neutron heating were calculated by a validated computational model for the neutronic simulation of the TRIGA Mark II research reactor using the Monte Carlo N-Particle transport code. Using the heat transfer equations according to the three modes of heat transfer, the thermal study of I-131 production by irradiation of the target in the central thimble showed that the temperatures of materials do not exceed the corresponding melting points. To validate this new design, several targets have been irradiated in the central thimble according to a preplanned irradiation program, going from4 hours of irradiation at a power level of 0.5MWup to 35 hours (7 h/d for 5 days a week) at 1.5MW. The results showthat the irradiated targets are tight because no iodine-131 was released in the atmosphere of the reactor building and in the reactor cooling water of the primary circuit.

Studies on the Regulation for Use, Metabolism, Intake, and Safety of Sodium Nitrite in Meat Products (육가공품에 사용되는 아질산염의 사용기준, 대사, 섭취량과 안전성에 대한 조사 연구)

  • Lee Keun-Taik;Kang Jong-Ok;Kim Cheon-Jei;Lee Mooha;Lee Sung Ki;Lee Joo-Yeon;Lee Ju-Woon;Cho Soo-Hyun;Joo Seon-Tea;Chin Koo B.;Choi Sung-Hee
    • Food Science of Animal Resources
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    • v.25 no.1
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    • pp.103-120
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    • 2005
  • During the 1970s, concern arose that cured meats contained high levels of residual nitrite and preformed nitrosamines. Therefore, the search for alternatives and alternative approaches to the use of nitrite have been still continued, however no complete alternative for nitrite has yet been identified. Recently, it was publicized in Korea that nitrite-containing meat products would be detrimental to health, about which consumers have been seriously concerned. Therefore, this study was carried out to inform the consumer of the safety status of nitrite and thereby to lead proper consumption of meat products. For assessing the safety of nitrite, data regarding the regulation for use, metabolism in human body, and dietary intake amounts of nitrite were collected and analyzed. The mean intake level of nitrite for Korean per capita was recently reported to be not more than 1% of ADI set by JECFA. On the contrary, a calculation indicated that the daily nitrite intake per capita from saliva by ingestion of vegetables in Korea would be about 300-fold higher than that from cured meats. In consideration of the low consumption amount of meat products per capita of Korean, that is, at least one fifth, compared to European and American, there is no particular reason to concern about the impairment of health by nitrite intake from meat products for Korean. However, any effort for the reduction of residual nitrite content in cured meats should be given with an idea to minimize the intake of nitrite even from the minor source.

Study on the Institutional Control Period Through the Post-drilling Scenario Of Near Surface Disposal Facility for Low and Intermediate-Level Radioactive Waste (중·저준위 방사성폐기물 천층처분시설에서 시추 후 거주시나리오 평가를 통한 폐쇄 후 제도적 관리기간 연구)

  • Hong, Sung-Wook;Park, Jin-Baek;Yoon, Jung-Hyun
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.12 no.1
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    • pp.59-68
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    • 2014
  • The public's access to the disposal facilities should be restricted during the institutional control period. Even after the institutional control period, disposal facilities should be designed to protect radiologically against inadvertent human intruders. This study is to assess the effective dose equivalent to the inadvertent intruder after the institutional control period thorough the GENII. The disposal unit was allocated with different kind of radioactive waste and the effects of the radiation dose to inadvertent intruder were evaluated in accordance with the institutional control period. As a result, even though there is no institutional control period, all were satisfied with the regulatory guide, except for the disposal unit with only spent filter. However, the disposal unit with only spent filter was satisfied with the regulatory guide after the institutional control period of 300 years. But the disposal unit with spent filter mixed with dry active waste could shorten the institutional control period. So the institutional control period can be reduced through the mixing the other waste with spent filter in disposal unit. Therefore, establishing an appropriate plan for the disposal unit with spent filter and other radioactive waste will be effective for radiological safety and reduction of the institutional control period, rather than increasing the institutional control period and spending costs for the maintenance and conservation for the disposal unit with only spent filter.

Design and Implementation of High Efficiency Transceiver Module for Active Phased Arrays System of IMT-Advanced (IMT-Advanced 능동위상배열 시스템용 고효율 송수신 모듈 설계 및 구현)

  • Lee, Suk-Hui;Jang, Hong-Ju
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.7
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    • pp.26-36
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    • 2014
  • The needs of active phased arrays antenna system is getting more increased for IMT-Advanced system efficiency. The active phased array structure consists of lots of small transceivers and radiation elements to increase system efficiency. The minimized module of high efficiency transceiver is key for system implementation. The power amplifier of transmitter decides efficiency of base-station. In this paper, we design and implement minimized module of high efficiency transceiver for IMT-Advanced active phased array system. The temperature compensation circuit of transceiver reduces gain error and the analog pre-distorter of linearizer reduces implemented size. For minimal size and high efficiency, the implented power amplifier consist of GaN MMIC Doherty structure. The size of implemented module is $40mm{\times}90mm{\times}50mm$ and output power is 47.65 dBm at LTE band 7. The efficiency of power amplifier is 40.7% efficiency and ACLR compensation of linearizer is above 12dB at operating power level, 37dBm. The noise figure of transceiver is under 1.28 dB and amplitude error and phase error on 6 bit control is 0.38 dB and 2.77 degree respectively.

The Influence of Cancer Fatigue, Quality of Sleep, and Environmental Sleep Disturbance on Comfort in Hospitalized Cancer Patients (입원한 암환자의 암피로, 수면의 질 및 환경적 수면장애가 안위에 미치는 영향)

  • Kim, Hee-Jin;Chang, Hee-Kyung
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.4
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    • pp.643-653
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    • 2020
  • This study is a descriptive research study to identify the relationship between cancer fatigue, quality of sleep, environmental sleep disturbance, and comfort perceived by hospitalized cancer patients. Data were collected with structured questionnaires from 113 cancer patients from a university hospital in J city, Gyengnam, from September 17 to November 5, 2019, and analyzed using SPSS 21.0, using independent t-test, one-way ANOVA, Scheffé test, Pearson's correlation coefficient, and stepwise multiple regression. The subjects' Comfort is significantly different depending on education level, Cancerous type, Radiation treatment status, Usual exercise status. The result showed that comfort was negatively correlated with cancer fatigue(r=-.609, p<.001), quality of sleep(r=-.478, p<.001), and environmental sleep disturbance(r=-.297, p=.001). The variables that had a significant effect on comfort were cancer fatigue(β=-.42, p<.001), subjective quality of sleep(β=-.30, p=.001), and cancer type(β=-.18, p<.015), and the explanatory power was 46.1%(F=27.24, p<.001). Based on these results, it is necessary to develop a program to improve the quality of sleep and to reduce the cancer fatigue by cooperating with medical and nursing staff in multidisciplinary ways to enhance the comfort of hospitalized cancer patients.

Genetic Variation Analysis of Early-heading Plant (Oryza sativa L.) Lines Derived from Gamma-ray Irradiation (방사선조사 유래의 조기출수 식물(Oryza sativa L.) 계통의 유전적 변이 분석)

  • Ryu, Jai-Hyunk;So, Hyun-Su;Lyu, Jae-Il;Kwon, Oh-Do;Lee, Young-Il;Jin, Il-Doo;Lee, Hyo-Yeon;Bae, Chang-Hyu
    • Korean Journal of Plant Resources
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    • v.25 no.1
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    • pp.142-151
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    • 2012
  • This study was carried out to evaluate genetic variation of early-heading rice (Oryza sativa L. cv. Dongjin 1) lines derived from gamma-ray ($^{60}Co$, 300 Gy) irradiation. The average heading date of the 5 early-heading lines in $M_7$ and $M_8$ generation was faster than that of untreated control as 11 (line ${\gamma}$-2), 10 (line ${\gamma}$-5), 6 (${\gamma}$-1 line), 5 (${\gamma}$-3) and 4 days (line ${\gamma}$-4), respectively. According to ISSR analysis, polymorphic rate of the early-heading lines (from 5.9% to 23.4%) was higher than that of control (4.3%). The result indicates that the gamma-ray promote variation at DNA level. When genetic variations of rps16-trnK region were evaluated by nucleotide analysis, nucleotide length of the rps16-trnK region was 664 bp in all the early-heading lines and control. Out of 5 sites of nucleotide transposition detected in the region, however, 2 sites were appeared only in the early-heading lines.

Effect on the Germination Growth and Variation Induction in Gamma Rays Irradiated seeds of Lilac Pink and Nursery Spiraea (술패랭이꽃과 층꽃나무 종자에 대한 감마선 조사가 발아, 생육 및 변이유발에 미치는 영향)

  • Park, Jae-Ok;Jeong, Byung-Joon;Park, Moon-Young;Kang, Si-Yong;Kwack, Soo-Nyeon;Park, Yun-Jum;Heo, Buk-Gu
    • Korean Journal of Plant Resources
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    • v.23 no.1
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    • pp.19-24
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    • 2010
  • This study was conducted to clarify effects on the germination, survival rate of seedlings, growth and variation induction of variants in gamma rays irradiated seed of lilac pink (Dianthus superbus var. longicalycinus) and nursery spiraea (Caryopteris incana). Seed germination and its germination rate were delayed over 90 Gy for lilac pink and 80 Gy for nursery psiraea. Fifty percent lethal time (LT50) level for lilac pink and nursery psiraea were 150 Gy and 100 Gy, respectively. Lilac pink and nursery psiraea were grown dwarf over 120 Gy treatment. We have produced 17 variants of lilac pink in $M_1$ generation, and selected the promising 4 variants in $M_2$ generation. We have also made 7 variants of nursery psiraea in $M_1$ generation, and selected the favorable 8 variants in $M_2$ generation.

A Study on Air Pollution and Thermal Factors in Underground Shopping Center of Pusan Area (부산시내 지하생활권의 공기오염도와 온열인자에 관한 조사연구)

  • Choi, Sung-Yong;Moon, Deog-Hwan;Lee, Jong-Tae;Song, In-Hyuk;Lee, Cha-Eun;Lee, Sung-Min
    • Journal of Preventive Medicine and Public Health
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    • v.27 no.3 s.47
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    • pp.505-516
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    • 1994
  • For the purpose of preparing the fundamental data on air pollution in underground shopping center and also contributing to the health improvement of residents, the authors measured the level of $SO_2,\;NO_2,\;TSP,\;CO,\;CO_2$ and also some related factors as air temperature, air movement, relative humidity and mean radiation temperature at inside and outside of underground shopping center in Pusan from January to February and from July to August 1994. The results were as follows : 1. The mean concentration of CO within the underground shopping center was $3.1{\pm}1.3ppm$ in winter and $2.1{\pm}0.9ppm$ in summer. There was a negative correlation (p<0.01) between inner CO concentration and temperature in summer and no correlation between inner CO concentration and outer CO concentration in underground shopping center 2. The mean concentration of COE within the underground shopping center was $876{\pm}353ppm$ in winter and $757{\pm}125ppm$ in summer. There was a negative correlation (p<0.01) between inner $CO_2$ concentration and air movement in summer and positive correlation (p<0.05) between inner $CO_2$ concentration and outer $CO_2$ concentration in underground shopping center. 3. The mean concentration of $SO_2$ within a underground shopping center was $0.036{\pm}0.019ppm$ in winter and $0.040{\pm}0.013ppm$ in summer. There was a positive correlation(p<0.01) between inner $SO_2$ concentration and temperature in summer and positive correlation between inner $SO_2$ concentration and outer $SO_2$ concentration in summer and winter in underground shopping center. 4. The mean concentration of $NO_2$ within a underground shopping center was $0.052{\pm}0.038ppm$ in winter and $0.042{\pm}0.016ppm$ in summer. There was a no correlation between inner $SO_2$ concentration and thermal factors in summer and winter and low correlation between inner $SO_2$ concentration and outer $SO_2$ concentration in underground shopping center 5. The mean concentration of TSP within a underground shopping center was $430{\pm}214{\mu}g/m^3$ in winter, $366{\pm}73{\mu}g/m^3$ in summer, and very in excess of the atmospheric environmental quality standards of Korea ($150{\mu}g/m3{\downarrow}$). There was low correlation between inner TSP concentration and temperature in summer and high correlation between inner TSP concentration and outer TSP concentration in underground shopping center.

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