• Title/Summary/Keyword: RFT

Search Result 43, Processing Time 0.024 seconds

A method for improving security and data accessibility in EMR systems based on GRID technologies (EMR 시스템을 위한 그리드 기술 기반의 보안성 및 데이터 접근성 향상 기법)

  • Shin, Dong-Min;Shin, Dong-Kyoo;Shin, Dong-Il
    • Proceedings of the Korean Information Science Society Conference
    • /
    • 2010.06c
    • /
    • pp.211-215
    • /
    • 2010
  • 지금까지 병원에서 사용하던 일반 종이차트를 벗어나 전자적으로 환자의 데이터를 기록하고 유전자 데이터를 이용하여 환자의 유사 질병까지 찾아 낼 수 있는 EMR(Electronic Medical Record 전자 의무 기록)이 개발되면서 의료계는 환자에게 더욱 신속하고 정확한 진료를 할 수 있게 되었다. 본 논문은 이에 그리드 환경을 접목하여 더 빠른 데이터 처리와 신뢰성 과 접근성을 높일 수 있는 방법을 제시한다. 첫째, 현재 기 개발된 EMR 시스템의 환경에서 인증된 사용자만이 스토리지에 접근 할 수 있도록 GSI Service를 이용하여 단일 인증 방식으로 보안성을 높이며 동시에 단 한번의 인증절차로 모든 자원을 활용 할 수 있다. 둘째, Replica Service를 이용하여 기존의 스토리지를 복제 하여 중요한 데이터 들을 보호하며 다수의 접근이 발생할 경우 처리를 분산 시킬 수 있는 방법을 제시한다. 그리드 미들웨어인 글로 버스가 스토리지와 서버 상에서 CA인증을 담당하며 파일 전송을 담당하는 RFT는 스토리지의 Replica를 관리하는 RLS서버의 정보를 사용 하여 멀리 떨어져 있는 복제된 데이터와의 관계를 기억하고 접근시 가장 가용성이 뛰어난 머신에서 데이터를 불러온다. 이런 글로버스의 서비스 들은 중요하며 고용량이 데이터를 분산 시킴으로써 데이터의 지역성을 높여 재사용 혹은 동시 접근시 처리 시간을 단축 시킬 수 있다. 본 논문은 그리드 환경을 접목하여 이러한 서비스를 구현할 경우 높은 신뢰성과 접근의 신속성을 보장할 수 있다고 제시한다.

  • PDF

Identification of the Regulatory Region Responsible for Vascular Tissue-Specific Expression in the Rice Hd3a Promoter

  • Pasriga, Richa;Cho, Lae-Hyeon;Yoon, Jinmi;An, Gynheung
    • Molecules and Cells
    • /
    • v.41 no.4
    • /
    • pp.342-350
    • /
    • 2018
  • Flowering time is determined by florigens. These genes include, Heading date 3a (Hd3a) and Rice FT 1 (RFT1) in rice, which are specifically expressed in the vascular tissues of leaves at the floral transition stage. To study the cis-regulatory elements present in the promoter region of Hd3a, we generated transgenic plants carrying the 1.75-kb promoter fragment of Hd3a that was fused to the ${\beta}$-glucuronidase (GUS) reporter gene. Plants expressing this construct conferred a vascular cell-specific expression pattern for the reporter gene. However, GUS was expressed in leaves at all developmental stages, including the early seedling stage when Hd3a was not detected. Furthermore, the reporter was expressed in roots at all stages. This suggests that the 1.75-kb region lackings cis-elements that regulate leaf-specific expression at the appropriate developmental stages. Deletion analyses of the promoter region indicated that regulatory elements determining vascular cell-specific expression are present in the 200-bp region between -245 bp and -45 bp from the transcription initiation site. By transforming the Hd3a-GUS construct to rice cultivar 'Taichung 65' which is defective in Ehd1, we observed that Ehd1 is the major regulatory element that controls Hd3a promoter activity.

A Clinical Study to Assess the Safety of GyoGam-Dan (교감단의 안정성과 임상적 적용에 대한 연구)

  • Kang, Hyung-Won;Kim, Ji-Hwon;Kim, Jin-Heong;Lee, Chung-Sik;Lee, Sang-Eon;Kim, Tae-Heon;Kim, Tae-Heon
    • Journal of Oriental Neuropsychiatry
    • /
    • v.19 no.3
    • /
    • pp.195-203
    • /
    • 2008
  • Objective: 'GyoGam-Dan' is known as a medicine to cure depression in Donguibogam (traditional Korean oriental medicine book). GyoGam-dan which is composed of Cyperi Rhizoma L. and Poria cum Radix pini has been used by basic prescription of asymptom related to all kinds of Qi(氣) disease. Although it has been clinically used for a long time, its safety have never been proved till now. Methods: We had collected data of 610 cases of patients taking 'GyoGam-Dan' at Wonkwang univ. oriental medical center for a period of three years (2005.3.09-2008.04.30). On the patients' blood, the levels of LFT and RFT were examined and the residual levels of heavy metals and pesticides were measured. Results: There were 610 patients who had taken GyoGam-Dan for about three years. In the patients, the most common diseases is depression, followed by palpitation, and then insomnia. Among the patients' estimations on its effectiveness, there were many of positive ones. The blood analyses of patients who had taken GyoGam-Dan did not show any problems and moreover there was not any problems in the levels of residual heavy metals and agricultural pesticides. Taken together, GyoGam-Dan was proved to be a safe medicine for health. Conclusions: Our clinical and chemical studies show that GyoGam-dan has the anti-stress effect and is a safe medicine of which side effect does not exist. Hereafter, Nigorous clinical trial on GyoGam-dan is required.

  • PDF

Effects of Long-Term Intake of Korean Medicine on Gynecology Patients' Livers and Kidneys; Panel Study - Focus on Before Intake, After 3, 6 Months - (장기간 한약복용이 부인과 환자의 간 및 신장기능에 미치는 영향: panel연구 - 복용 전과 후 3, 6개월 비교를 중심으로 -)

  • Yang, Junmo;Sung, Dongmin;Kim, Eu Gene;Lee, Sundong
    • The Journal of Korean Medicine
    • /
    • v.41 no.1
    • /
    • pp.84-92
    • /
    • 2020
  • Objectives: To observe the effects on liver and kidney of gynecology patients' during long term Korean Medicine. Methods: This research was conducted as a panel study on 29 female gynecology patients at Korean medicine clinic and compares their conditions before, 3 months after, and 6 months after Intake of Korean medicine. This analysis was conducted to frequency(%), repeated measure ANOVA and significantly statistics was p<0.05, confidence interval. Results: The most common conditions among the subjects were polycystic ovary syndrome, endometriosis, adenomyosis, and uterine myoma. Except in a few instances, liver functions (AST, ALT, γ-GTP) were within the normal range before and after the intake of Korean medicine. Further, while there was a slight change in liver functions when three months and six months after the intake, but there was no statistical significance (p>0.05). As for the kidney functions (BUN, Creatinine, BUN/Creatinine), they were within the normal range before and after the intake of Korean medicine. Further, while there was a slight change in kidney functions three months and six months after the intake, there was no statistical significance(p>0.05) either. Conclusions: Based on these results, it can be concluded that Korean medicine does not have a negative impact on the gynecology patients' liver and kidney.

A Study on the VHCF Fatigue Behaviors of Hydrogen Attacked Inconel 718 Alloy (수소취화된 인코넬 718의 VHCF(Very High Cycle Fatigue) 피로특성에 관한 연구)

  • Suh, Chang-Min;Nahm, Seung-Hoon;Kim, Jun-Hyong;Pyun, Young-Sik
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.40 no.7
    • /
    • pp.637-646
    • /
    • 2016
  • This study is to investigate the influence of hydrogen attack and UNSM on fatigue behaviors of the Inconel 718 alloy. The decrease of the fatigue life between the untreated and the hydrogen attacked material is 10-20%. The fatigue lives of hydrogen attacked specimen decreased without a fatigue limit, similar to those of nonferrous materials. Due to hydrogen embrittlement, about 80% of the surface cracks were smaller than the average grain size of $13{\mu}m$. Many small surface cracks caused by the embrittling effect of hydrogen attack were initiated at the grain boundaries and surface scratches. Cracks were irregularly distributed, grew, and then coalesced through tearing, leading to a reduction of fatigue life. Results revealed that the fatigue lives of UNSM-treated specimens were longer than those of the untreated specimens.

Short-term Effect of Gyeongsangnam-do Wellness Tourism on Inflammatory and Immune System Markers, Emotion, Fatigue, Stress, Quality of Life, and Quality of Sleep (경상남도 웰니스관광의 염증면역지표, 자율신경균형, 정서, 피로, 스트레스, 삶의 질 및 수면의 질 개선에 미치는 단기효과)

  • Lee, Sae-Rom;Lee, Ye-Li;Lee, Sang-Yeoup
    • Journal of The Korean Society of Integrative Medicine
    • /
    • v.9 no.3
    • /
    • pp.19-35
    • /
    • 2021
  • Purpose : Recently, there has been a growing social interest in aging well. Consequently, wellness tourism has begun to attract attention. However, no studies on whether wellness tourism has any objective health benefits have been carried out yet. In this study, we assess the health benefits as well as the degree of improvement in health of a wellness tourism program. Methods : The study involved 30 adults over the age of 19 who live in the Gyeongsangnam-do region. Participants were evaluated on health indicator before and after participating in wellness tourism program. Participants took heart rate variability (HRV) test, and LFT, RFT, CBC, FBS HbA1C, and CRP test were conducted before and after the tour. Additionally, a survey was conducted before and after the program, and participant satisfaction was evaluated. Statistical differences in the tests conducted before and after the program were analyzed using a design t-test, a Wilcoxon signed-rank test, and McNemar's test. Results : The study showed that participants were very satisfied with and had significant health improvements after the wellness tourism program. The program was also found to be beneficial in improving participants' emotions as follows: BDI (p<.001), fatigue recovery (p=.006), stress relief (p=.003), improved quality of life (p<.05), and improved sleep quality (p<.001). Conclusion : Wellness tourism programs are specifically beneficial for improving participants' emotions (depression, anxiety), fatigue, stress levels, quality of life, and sleep. Therefore, they are beneficial to the overall health. Further research in the future by way of a follow-up study on the long-term effects on health after short-term interventions will provide more validation data.

Clinical study of the 15 patients survived after acute paraquat intoxication (급성 파라콰드중독후 생존한 15예환자의 임상적 고찰)

  • Kim Dong-Woung
    • Journal of Society of Preventive Korean Medicine
    • /
    • v.3 no.1
    • /
    • pp.55-65
    • /
    • 1999
  • From January 1994 to April 1997, there was 15 survivals who was admitted to the department of internal medicine, Wonkwang Oriental Medicine Hospital in Cheun-ju, after ingestion of paraquat, and treated with Oriental and western medicine therapy. For the patients, I investigated clinical symptoms, gastroduodenoscopy, intake by oral and parenteral route, and output by urine and stool, serum ALP, AST. ALT, Bilirubin, BUN, Creatinine level and urine analysis. On admission day, the LFT level was as follows. The serum mean ALP, AST, ALT, Total Bilirubin and Direct Bilirubin was $10.05{\pm}2.75\;KAU$, $66.67{\pm}9.88\;IU/L$, $43.80{\pm}7.74\;IU/L$, $1.89{\pm}1.22\;mg/dl$ and $1.10{\pm}1.14\;mg/dl$ respectively. After that day, administered Gamdutang and checked the mean LFT level regullary. Until the 3rd day, the mean ALP, AST, ALT, Total Bilirubin and Direct Bilirubin level was $11.01{\pm}3.16\;KAU$, $56.47{\pm}7.19\;IU/L$, $59.00{\pm}7.57\;IU/L$, $2.54{\pm}1.78\;mg/dl$, $1.64{\pm}1.59\;mg/dl$ respectively. From 4th day to 7th day, the mean ALP; AST, ALT, Total Bilirubin and Direct Bilirubin level was $12.51{\pm}3.49\;KAU$, $77.85{\pm}7.17\;IU/L$, $58.00{\pm}9.09\;IU/L$, $2.54{\pm}1.97\;mg/dl$, and $1.80{\pm}1.81\;mg/dl$ respectively. From 8th day to 10th day, the mean ALP, AST, ALT, Total Bilirubin and Direct Bilirubin level was $12.43{\pm}3.14\;KAU$, $41.13{\pm}6.49\;IU/L$, $50.40{\pm}7.17\;IU/L$, $1.66{\pm}1.90\;mg/dl$ and $1.14{\pm}1.50\;mg/dl$ respectively. From 11th day to 14th day, the mean ALP, AST, ALT, Total Bilirubin and Direct Bilirubin level was $12.30{\pm}3.25\;KAU$, $31.07{\pm}3.85\;IU/L$, $43.33{\pm}5.49\;IU/L$, $1.62{\pm}1.95\;mg/dl$, $1.17{\pm}1.71\;mg/dl$ respectvely. On admission day, the mean RFT level as follows. Serum BUN and Creatinine level was $28.73{\pm}5.19\;mg/dl$ and $1.82{\pm}1.27\;mg/dl$ respectively. After that day, administered Gamdutang and checked the mean RFT level regullary. Until the 3rd day, the mean BUN and Creatinine level was $32.12{\pm}5.65\;mg/dl$ and $2.31{\pm}0.45\;mg/dl$ respectively. From 4th day to 7th day, the mean BUN and Creatinine level was $31.07{\pm}5.47\;mg/dl$ and $1.92{\pm}0.79\;mg/dl$ respectively. From 7th day to 10th day, the mean BUN and Creatinine level was $17.47{\pm}3.57\;mg/dl$ and $1.33{\pm}0.59\;mg/dl$ respectively. From 11th day to 14th day, the mean BUN and Creatinine level was $11.93{\pm}3.16\;mg/dl$, $1.27{\pm}0.38\;mg/dl$ respectively.

  • PDF

Effects of Definitive Chemoradiotherapy on Respiratory Function Tests and Quality of Life Scores During Treatment of Lung Cancer

  • Duman, Evrim;Yildirim, Mustafa;Kaya, Vildan;Ozturk, Duriye;Inal, Aysun;Akarsu, Zeynep;Gunduz, Seyda;Yildiz, Mustafa
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.15
    • /
    • pp.6779-6782
    • /
    • 2015
  • Background: Chemoradiotherapy is an important treatment modality for lung cancers. The aim of this study was to investigate alterations in, as well as the interrelationship between, lung function and quality of life of patients receiving chemoradiotherapy due to locally advanced non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) limited to the thorax. Materials and Methods: The study included patients receiving definitive chemoradiotherapy for lung carcinoma. The respiratory function of the patients was assessed by measuring forced expiratory volume in 1 s per unit (FEV1) and forced expiratory volume in 1s per unit of vital capacity (FEV1/VC) before, in the middle of and after treatment. During the study, EORTC QLQ C30 and LC13 questionnaires developed by the Committee of the European Organization for Research and Treatment of Cancer (EORTC) were employed to evaluate the quality of life on the same day as respiratory function tests (RFT). Findings: The study included 23 patients in total: 19 (82.6%) diagnosed with NSCLC and 4 (17.4%) with SCLC. The average percentage FEV1 was $55.6{\pm}21.8%$ in the pre-treatment period, $56.2{\pm}19.2%$ in the middle of treatment and $60.4{\pm}22%$ at the end of treatment. The improvement in functional scores, symptom scores and general health scores during treatment was not statistically significant (P= 0.568, P= 0.734, P= 0.680, P=0.757 respectively). Conclusions: Although this study showed an improvement in respiratory function and quality of life of patients during treatment with thoracic chemoradiotherapy, no statistically significant results were obtained. While evaluating the effectiveness of treatments for lung carcinoma, the effects of treatment on respiratory function and quality of life should be considered.

Evaluation of Mechanical Properties and Fatigue Behavior of STS 304L due to Plastic Working (소성가공에 따른 STS 304L 재료의 기계적 특성 및 피로평가)

  • Shim, Hyun-Bo;Kim, Young-Kyun;Suh, Chang-Min
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.41 no.7
    • /
    • pp.635-643
    • /
    • 2017
  • The purpose of this study is to investigate the influence of the cold reduction rate and an ultrasonic fatigue test (UFT) on the fatigue behaviors of STS 304L. The tensile strength, yield strength, hardness value and fatigue limit in the UFT fatigue test linearly increased as thickness decreased from 1.5 mm to 1.1 mm, as the cold reduction rate of STS 304L increased. As a result of the UFT fatigue test (R = -1) of four specimens, the fatigue limit of the S-N curve formed a knee point in the region of $10^6$, and the 2nd fatigue limit caused by giga cycle fatigue did not appeared. In the case of t = 1.1 mm, the highest fatigue limit was 345 MPa, which was 64.3% higher than the original material (t = 1.5 mm). As a result of the UFT fatigue test of STS 304L, many small surface cracks occurred, grown, coalesced while tearing.

Study on VHCF Fatigue Behaviors and UNSM Effects of Hydrogen Attacked STS 316L (수소취화된 스테인리스강 316L의 VHCF(Very High Cycle Fatigue) 피로특성과 UNSM 효과에 관한 연구)

  • Nahm, Seung-Hoon;Baek, Un-Bong;Suh, Chang-Min;Pyun, Young-Sik
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.41 no.11
    • /
    • pp.1011-1020
    • /
    • 2017
  • This study was conducted to investigate the material properties of stainless steel 316L specimens of untreated and UNSM treated material, hydrogen attacked material(100 bar, $300^{\circ}C$ at 120 h) and UNSM treated hydrogen attacked material at room temperature. Results demonstrated that the hydrogen attacked materials showed a tendency toward a slightly decreased fatigue strength, while the hydrogen embrittlement effect was smaller than the S-N curve of conventional untreated material. As compared to untreated material, the fatigue limit of the UNSM treated material increased by 43.8%, while it was 57.1% higher in the UNSM treated hydrogen attacked material than in untreated hydrogen attacked material. The plastic deformation layer was ${\sim}152{\mu}m$ thick, as confirmed by maps showing the level of local plastic deformation affected by the UNSM treatment in three ways: an image quality map, inverse pole figure map, and kernel average misorientation map captured via electron back scatter diffraction. Owing to hydrogen embrittlement, about 90% of surface cracks were smaller than the average grain size of $35{\mu}m$.