• Title/Summary/Keyword: RESPONSE 2000

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Gamma Knife Radiosurgery for Juxtasellar Tumors (터어키안 주변종양에 대한 감마나이프 방사선 수술)

  • Chang, Jong Hee;Chang, Jin Woo;Park, Yong Gou;Chung, Sang Sup
    • Journal of Korean Neurosurgical Society
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    • v.29 no.10
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    • pp.1345-1351
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    • 2000
  • Objective : Around the sellar area, there are many important structures. But, the optimal radiation dosage for minimal toxicity to surrounding neural tissue has not been firmly established. The purpose of this study is to evaluate the radiosurgical outcome of juxtasellar tumors and to investigate the relationship between radiation dosage and toxicity to neural tissue. Method : Between May 1992 and June 2000, we treated 65 juxtasellar tumors by using the Leksell Gamma Knife. Among them, 52 patients who could be followed more than 1 year were included in this study. The radiosurgical dosage to the optic pathway, cavernous sinus, Meckel's cave, hypothalamus, pituitary gland and stalk, and brain stem was analyzed and correlated with clinical outcome. The mean follow-up period was 33.5 months(range 12.2- 99.0 months). Result : The clinical response rate was 69.2%. The volume response rate was 61.0% and the radiologic control rate was 92.7%. There were 4 complications(7.7%) of 2 trigeminal neuropathy, 1 abducens nerve palsy, and 1 trigeminal and transient abducens nerve palsy. The optic apparatus appeared to tolerate doses greater than 10Gy. The risk of cranial nerve complications in cavernous sinus seemed to be related to doses of more than 16Gy. In 3 of 4 patients who received more than 16Gy to cavernous sinus, the abducens or trigeminal neuropathy occurred. Also, one patient who received more than 15Gy to the Meckel's cave, trigeminal neuropathy developed. The hypothalamus, pituitary gland and stalk, and brain stem were relatively tolerable to radiation. Conclusion : Gamma Knife radiosurgery seems to be an effective method to control the growth of juxtasellar tumors. To avoid injury to surrounding important neural tissue, careful dose planning and further study for radiation toxicity to neural tissue were needed.

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A Study on the Impact of China's Trade-related Policy Changes on Export Performance of Korean Manufacturing Companies in China (중국의 무역관련 정책 변화가 현지 진출 한국계 기업의 수출성과에 미치는 영향에 관한 연구)

  • Hong, Jae-Sung;Lee, Yong-Keun
    • International Commerce and Information Review
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    • v.16 no.1
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    • pp.69-88
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    • 2014
  • According to the previous study, after 2000s, factors of the Chinese government's trade policy changes would be a significant burden on the company. However, many previous studies were limited to the response strategy by judicial analysis. Therefore, this study aims to analyze the factors that affect the export performance of Korean manufacturing companies in China. Also, by using that result, I would like to provide advises for entered the korean companies in Chinese market As the results, I knew that export performance are most heavily influenced by labor policy factor and the fallowing is exchange rate policy factor. Eventually, Most of our country companies entering in china were affected changes in the exchange rate policy factor, but many company were manufacturing-type businesses to economize labor costs. Therefore, corporate and governmental response strategies are needed for that's companies.

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The Analysis of Factors that Affect Attitudes toward the New Digital Revolution (새로운 디지털 혁명에 대한 태도에 영향을 미치는 요인 분석)

  • Jun, Bong-Gi
    • Journal of Digital Convergence
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    • v.12 no.6
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    • pp.333-339
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    • 2014
  • In the late 2000's, a smart phone caused by the digital revolution has led to abrupt changes from our life. The internet of thing (IoT), which is considered as a next digital revolution, will be scrutinized in this paper. Students, who use smart phones in Silla University, were selected for the sample-frame. Approximately 78% students replied with a positive response to the digital revolution admit the new era with the intellectual curiosity and challenge. On the other hand, about 48% students showed uneasy response to the new civilization due to the lack of privacy and security issues of IoT; furthermore, friendship was their apprehension. This paper will provide potentially useful insights and directions for examining factors that affect different manners toward the next digital revolution.

Analysis and design of metal-plate-connected joints subjected to buckling loads

  • Hussein, R.
    • Structural Engineering and Mechanics
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    • v.9 no.5
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    • pp.417-432
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    • 2000
  • A comprehensive analytic study has been conducted to investigate the instability problems of metal-plate-connected (MPC) joints in light frame trusses. The primary objective in this study is to determine the governing factors that constitute the buckling of the metal connectors and their effects on the structural response of joints. Another objective is to recommend design curves for the daily structural design of these joints. The numeric data presented in this paper has emerged from a broad base that was founded on over 350 advanced computer simulations, and was supported by available experimental results obtained by others. This basic-to-applied research includes practical engineering parameters such as size of gaps, shear lengths, gauge (plate thickness) of connectors, size of un-braced areas, failure modes, and progressive disintegration of joints. Square-end members have been emphasized though the results cover the custom-made fitted joints. The results indicate that chord shears cause and dominate the buckling of MPC joints, and the shear length has a more pronounced effect than the size of gaps. Further, large gauges and small un-braced areas improve the buckling response. Several practical recommendations have been suggested throughout the paper such as keeping the ratio of gap/shear length below 3/4 for improving the buckling strength. The study reveals that multi-area joints should not be simplified as single web-to-chord MPC joints such as keeping the ratio of gap/shear length below 3/4 for improving the buckling strength, even where one web is in tension and the other in compression. Finally, the results obtained from this study favorably agree with experimental data by others, and the classic buckling theories for other structural components.

Effects of Chromium Supplementation and Lipopolysaccharide Injection on Physiological Responses of Weanling Pigs

  • Lee, D.N.;Weng, C.F.;Yen, H.T.;Shen, T.F.;Chen, B.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.4
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    • pp.528-534
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    • 2000
  • Sixteen specific pathogen free 4-wk-old crossbred weanling pigs were allotted into a $2{\times}2$ factorial design to evaluate chromium picolinate (CrPic) on growth and physiological responses. Two factors included (1) no Cr or 400 ppb Cr supplementation from chromium picolinate and (2) lipopolysaccharide (LPS) injection on day 21 (d 21) and 35 (d 35) compared to saline application. Plasma samples and rectal temperature were obtained from all piglets before (h 0) and at 2 h (h 2), 4 h (h 4), 8 h (h 8), and 24 h (h 24) after LPS injection ($200{\mu}g/kg$ BW, intraperitoneally). The rectal temperature on d 21 was significantly decreased (p<0.05) of about $0.36^{\circ}C$ with Cr supplementation before LPS injection. After LPS injection, the daily gain of piglets was decreased during d 35-38. Supplementation of Cr had no effect in general on growth performance particularly after LPS injection. The plasma glucose, triglycerides and urea nitrogen concentrations were changed in different ways after LPS injection. Plasma cortisol level was significantly elevated at h 2 after LPS injection on d 21 and d 35. The supplementation of Cr in the diet can delayed plasma cortisol release on d 35. The results suggest that 400 ppb Cr supplementation from CrPic may modulate the physiological response during immune stress in weanling pigs.

Effects of Aspergillus oryzae Fermentation Extract on In Situ Degradation of Feedstuffs

  • Chiou, P.W.S.;Chen, C.;Yu, B.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.8
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    • pp.1076-1083
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    • 2000
  • The aim of this study was to evaluate the effect of Aspergillus oryzae fermentation extract (AFE) on in situ degradation of the various concentrates, forages and by-products in Taiwan. The in situ trial was conducted to determine the effect of AFE on the rate of ruminal degradation of dry matter (DM), organic matter (OM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) of the various local available feedstuff commonly used for dairy cattle. Two ruminal fistulated cows were arranged into a two by two switchback trial. Two dietary treatments were control without AFE inclusion diet and diet with 3 g of AFE (Amaferm) added daily into the total mixed ration (TMR). Results showed that effect of AFE inclusion on the ruminal degradability of concentrates vary; soybean meal is the most responsive feedstuff, corn is the next, whereas full-fat soybean did not response the AFE inclusion at all. The inclusion of AFE significantly depressed most of the nutrient degradation of the concentrates of soybean meal in the first 12-hour in situ incubation. The effect declined in the next 12 hours. Rapeseed meal showed a different trend of response: addition of AFE improved its NDF degradation. The inclusions of AFE significantly improved ADF degradation of roughage after 24 or 48 hours of incubation. However, corn silage and peanut-vines showed a different trend. Effects of AFE inclusion on the by-products degradability were inconsistent. Most of nutrients in rice distillers grain and some in beancurd pomace did show increased degradation by the AFE inclusion.

A Study on the Extraction and Integration of Learning Object Meta-data using Web Service of Databases (DBMS의 웹서비스를 이용한 학습객체 메타데이터 추출 및 통합에 관한 연구)

  • Choe, Hyun-Jong
    • Journal of The Korean Association of Information Education
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    • v.7 no.2
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    • pp.199-206
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    • 2003
  • XML is becoming a new developing tool of web technology because of its ability of data management and flexibility in data presentation. So it's well researched that the reusability and integration with learning objects such as text, image, sound, video and plug-in programs of web contents in computer education. But the research for storing, extracting and integrating metadata about learning object was needed prior to implementing online learning system to integrate and manage it. Therefore this study propose a new method of using web service of DBMS for extracting learning object's metadata in database server which located in 3-tier system. To evaluate the efficiency of proposed method, The test server and two DBMSs(MS SQL Server 2000 and Oracle 9i) which have 30 metadata was implemented and the response time of it was measured. The response time of it was short, but in order to using this method the additional programming with SAX/DOM was necessary.

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A Study on Changes in Industrial Value Added Response to Oil Prices in Korean (한국경제의 유가에 대한 산업부가가치 반응변화 연구)

  • Yoon Kyung Kim;Ji Whan Kim
    • Economic and Environmental Geology
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    • v.56 no.4
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    • pp.447-456
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    • 2023
  • Even after 2000, oil prices rose enough to be comparable to the past, but the impact on economic variables was relatively stable. Therefore, this study tries to empirically examine that the response of the Korean economy to oil prices has changed since the 1998 financial crisis, when there was a structural change in the Korean economy. Through empirical analysis, it was tested that the influence of oil prices and producer prices on consumer prices had changed in the period before and after 1998, and that the influence of producer prices on the value-added ratio by industry sector also changed. This means that the transfer of the increase in production cost to consumer prices has been alleviated, and the impact on added value has also been alleviated. Various studies should be conducted to understand the causes of the empirical results, such as changes in the relationship between producer prices and consumer prices, factors in the industrial sector due to rising oil prices, and changes in products.

ON THE GALACTIC SPIRAL PATTERNS: STELLAR AND GASEOUS

  • MARTOS MARCO;YANEZ MIGUEL;HERNANDEZ XAVIER;MORENO EDMUNDO;PICHARDO BARBARA
    • Journal of The Korean Astronomical Society
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    • v.37 no.4
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    • pp.199-203
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    • 2004
  • The gas response to a proposed spiral stellar pattern for our Galaxy is presented here as calculated via 2D hydrodynamic calculations utilizing the ZEUS code in the disk plane. The locus is that found by Drimmel (2000) from emission profiles in the K band and at 240 ${\mu}m$. The self-consistency of the stellar spiral pattern was studied in previous work (see Martos et al. 2004). It is a sensitive function of the pattern rotation speed, $\Omega$p, among other parameters which include the mass in the spiral and its pitch angle. Here we further discuss the complex gaseous response found there for plausible values of $\Omega$p in our Galaxy, and argue that its value must be close to $20 km s^{-l}\;kpc^{-1}$ from the strong self-consistency criterion and other recent, independent studies which depend on such parameter. However, other values of $\Omega$p that have been used in the literature are explored to study the gas response to the stellar (K band) 2-armed pattern. For our best fit values, the gaseous response to the 2-armed pattern displayed in the K band is a four-armed pattern with complex features in the interarm regions. This response resembles the optical arms observed in the Milky Way and other galaxies with the smooth underlying two-armed pattern of the old stellar disk populations in our interpretation. The complex gaseous response appears to be related to resonances in stellar orbits. Among them, the 4:1 resonance is paramount for the axisymmetric Galactic model employed, and the set of parameters explored. In the regime seemingly proper to our Galaxy, the spiral forcing appears to be marginally strong in the sense that the 4:1 resonance terminates the stellar pattern, despite its relatively low amplitude. In current work underway, the response for low values of $\Omega$p tends to remove most of the rich structure found for the optimal self-consistent model and the gaseous pattern is ring-like. For higher values than the optimal, more features and a multi-arm structure appears.

Dose Response Relationship in Local Radiotherapy for Hepatocellular Carcinoma (원발성 간암의 국소 방사선치료 시 선량반응 관계)

  • Park Hee Chul;Seong Jinsil;Han Kwang Hyub;Chon Chae Yoon;Moon Young Myoung;Song Jae Seok;Suh Chang Ok
    • Radiation Oncology Journal
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    • v.19 no.2
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    • pp.118-126
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    • 2001
  • Purpose : In this study, it was investigated whether dose response relation existed or not in local radiotherapy for primary hepatocellular carcinoma. Materials and Methods : From January 1992 to March 2000, 158 patients were included in present study. Exclusion criteria included the presence of extrahepatic metastasis, liver cirrhosis of Child's class C, tumors occupying more than two thirds of the entire liver, and performance status on the ECOG scale of more than 3. Radiotherapy was given to the field including tumor with generous margin using 6, 10-MV X-ray. Mean tumor dose was $48.2{\pm}7.9\;Gy$ in daily 1.8 Gy fractions. Tumor response was based on diagnostic radiologic examinations such as CT scan, MR imaging, hepatic artery angiography at $4\~8$ weeks following completion of treatment. Statistical analysis was done to investigate the existence of dose response relationship of local radiotherapy when it was applied to the treatment of primary hepatocellular carcinoma. Results : An objective response was observed in 106 of 158 patients, giving a response rate of $67.1\%$. Statistical analysis revealed that total dose was the most significant factor in relation to tumor response when local radiotherapy was applied to the treatment of primary hepatocellular carcinoma. Only $29.2\%$ showed objective response in patients treated with dose less than 40 Gy, while $68.6\%\;and\;77.1\%$ showed major response in patients with $40\~50\;Gy$ and more than 50 Gy, respectively. Child-Pugh classification was significant factor in the development of ascites, overt radiation induced liver disease and gastroenteritis. Radiation dose was an important factor for development of radiation induced gastroduodenal ulcer. Conclusion : Present study showed the existence of dose response relationship in local radiotherapy for primary hepatocellular carcinoma. Only radiotherapy dose was a significant factor to predict the objective response. Further study is required to predict the maximal tolerance dose in consideration of liver function and non-irradiated liver volume.

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