• Korean Journal of Acupuncture
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• v.37 no.2
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• pp.76-87
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• 2020

Objectives : Bee venom has been widely practiced in many countries around the world. The number of clinical trials and biochemical researches on bee venom has been constantly increasing. The objective of this study is to analyze the trend of research on bee venom using bibliometric approach, a quantitative analytical method. Methods : We searched articles about bee venom which were published from 2000 to 2019 from Web of Science Database. Original and review articles published in English were included and data were extracted in terms of publication year, country, journal, keywords, organizations, and authors. Trends in bee venom research were visualized using VOSviewer program. Results : 1,547 English articles about bee venom were identified and analyzed. South Korea is a main hub in the field of bee venom research. Research organizations in South Korea showed high link strength with domestic organizations as well as with international organizations. A keyword analysis showed the following three major types of studies: studies on components of bee venom, studies on allergy and immune response, and clinical research of bee venom therapy. Conclusions : This study provides a macroscopic overview of the research on bee venom. This bibliometric analysis has identified influential authors and organizations in the field on bee venom research and provides a useful guideline to researchers who are in search of contributory research topics.

• Korean Journal of Adult Nursing
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• v.14 no.1
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• pp.44-52
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• 2002

Purpose: This study is to identify the effects of muscle relaxation therapy on mood state and job stress of clinical nurses, finally to purpose the bases of nursing intervention to increased of work efficiency and job satisfaction. Method: The research design was a nonequivalent control group pretest-posttest design. The subjects were 50 clinical nurses (23 for experimental group), who were working for 1-5 years in medical and surgical ward from the 2 C-University medical center in Seoul. This study was conducted from May 12 to July 25, 2000. The muscle relaxation therapy was performed 5 weeks to experimental group. The experimental group participated in the muscle relaxation training sessions for 20minutes twice a week during five weeks. The level of job stress was measured by nurses occupational stress scale. The level of Psychological response was measured by Profile of mood state. The data was analyzed using descriptive statistics, $X^2$-test, t-test, paired t-test. Result: The results of this study were as follows: The experimental group who received the muscle relaxation therapy showed more reduction of job stress level (t=1.35, p=0.038) and profile of mood state level (t=2.27, p=0.027) after therapy than those in control group. Conclusion: This study reveals that the muscle relaxation therapy is effective in reduction of nurse's job stress and promotion of mood state. So the researcher thinks that it is useful in reduction of job stress and increased of job satisfaction in hospital.

• The Research Journal of the Costume Culture
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• v.8 no.3
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• pp.460-476
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• 2000

The purpose of this study was, accordingly, to examine male college student's general body consciousness and their actual condition of wearing clothing, as it's assumed that clothing, which everyone must always wear, might be effective in making up for the physical defect. The findings of this study were as follows : 1. Male College Students'Body Consciousness : They expressed some dissatisfaction with their own body, and they were most discontented with their height, among their bodies. They thought of the western-style shape as an ideal one, as what's considered by them to be ideal was thinner a little than them, being taller with wider shoulder, longer legs, smaller and white face. 2. Male College Students'Characteristics of Clothing Purchasing Behavior : In purchasing clothing, male college students were slightly sensitive about the physical part with which they wasn't satisfied. The clothing pattern preferred by them was an abstract one, and their favorite color was white or black. The greatest number of them put most emphasis on design in buying clothing, and they purchased clothing mainly at special fashion shop. On the whole, they showed an affirmative response toward wearing Korean costume, and they also had a positive opinion about the purchase of reformed Korean dress for everyday life. 3. Male College Students'Characteristics of Wearing Clothing : They appeared not to consider making up for physical weakness. Male college students favored aloha shirt and trousers when they went out. Male college students purchase clothing in consideration of individual, manly, classical, tender, or comfortable factors. 4. Relationship of Body Consciousness to Wearing Behavior : The degree to which they considered covering up physical weakness in wearing clothing was examined, by dividing them into two groups : one was a group that thought their own shape normal, and the other was a group that didn't think of their own shape as normal. As a result, both groups appeared not to consider covering up physical weakness.

• Journal of the korean academy of Pediatric Dentistry
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• v.27 no.1
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• pp.77-84
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• 2000

Although ferric sulfate has been proposed as an alternative to formocresol in pulpotomy treatment in primary teeth, it has been given little concern regarding its cytotoxicity and mutagenicity. In the present study, we assessed the in vitro genotoxic effect of a ferric sulfate on human gingival fibroblast cell line (HGF-1). DNA damage was evaluated using comet assay (single cell alkaline gel electrophoresis) and obtained the results as follows: 1. A dose-response relationship was found between ferric sulfate concentrations (0 to 5mM) and DNA damages. 2. Above the concentration of 0.1mM, DNA damage was significantly increased than those of the control (p<0.05). 2. At the fixed concentration of 0.05mM, no significant difference was found between exposure time and DNA damage. These findings suggest that ferric sulfate as a pulpotomy agent can induce DNA damage in human gingival fibroblasts.

• Composites Research
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• v.13 no.1
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• pp.89-97
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• 2000

Fatigue damage detection and vibration sensing for a laminated composites and impact location detection for a steel beam have been carried out using optical fiber sensor. Intensity based optical fiber sensor is constructed by placing two cleaved fiber end in a hollow glass tube, and multiple reflection within the cavity is considered. Fatigue signals are measured by embedded optical fiber, surface mounted optical fiber sensor and strain gage simultaneously. For vibration sensing, optical fiber sensor is mounted on the carbon fiber composite beam and its response to free vibration and forced vibration is investigated. In impact location detection, two optical fiber sensors are used and the information obtained from two sensors is arrival time delay of vibration caused by impact. Impact location can be calculated from this time delay. The obtained results show that the intensity based optical fiber sensor provide reliable data during long-term fatigue loading, unlike strain gage which deteriorate during the early part of the fatigue test. Optical fiber sensor signals coincide with gap sensor in vibration sensing. The precise locations of impact can be detected within 4.1% error limit.

• Journal of Acupuncture Research
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• v.26 no.5
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• pp.57-63
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• 2009

Objectives : Since the Front Points are treated as response zone, it can be used for the diagnosis and treatment of disease in viscera and bowels. Jeonjung($CV_{17}$) is the Front Point of SIMPO, it is related with cardiovascular, neuro-psychiatrical disease in aspect of Oriental Medicine. This research is for clarifying relations with palpation of the Jeonjung($CV_{17}$) and autonomic nerve system by comparing HRV and SRI(Stress Reaction Index). Methods : This study was proceeded for three months, from June 2009 to September 2009. Among 31 healthy volunteers, 13 subjects who complained the pressure pain around Jeonjung($CV_{17}$) are classified pressure pain group and 18 subjects who had no pain around Jeonjung($CV_{17}$) as normal group. All subjects had their HRV(SA-2000E: Medicore Co..Ltd. Korea) and SRI measured at visit. We studied the difference of HRV between two groups.(Statistics by Student t-test, p<0.05) Results : LF normalization of the pressure pain group were significantly higher than those of the normal group. HF normalization of the pressure pain group were significantly lower than those of the normal group. Compared with those of the normal group, total SRI of the pressure pain group were low but it's not significant. Conclusions : The results of HRV of the pressure pain group show that pressure pain around Jeonjung($CV_{17}$) is related to mental stress and autonomic disturbance.

• Journal of the Korea Computer Graphics Society
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• v.6 no.1
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• pp.11-17
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• 2000

We present collision-handling method that includes self-penetration in the case of the colliding between rigid and deformable objects. The collision between objects is detected through the overlap test to the hierarchical structures of the objects. For detecting the collision between the objects at in-between frame, we try overlap test using the structures of a dummy and the rigid objects in addition to the test between the rigid and deformable objects. The dummy object is made from the rigid objects moving direction. When collision occurs, a deformable object must be deformed, as the object doesn't permit penetration. Self-penetration may occur during the object is deformed. It is rapidly detected between the object and a dummy object of another type. The dummy object is made from the object's deformation area between two continuous frames. We constrain the object is deformed until it is self-contacted. Our method can be applied without concerning of the shape of a object.

• Proceedings of the Korean Geotechical Society Conference
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• 2000.03b
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• pp.173-182
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• 2000

To find axial and lateral responses of impact-driven H piles in embankment(SM), the H piles are instrumented with electric strain gages, dynamic load test is performed during driving, and then the damage of strain gages is checked simultaneously. Axially and laterally static load tests are performed on the same piles after one to nine days as well. Then load-settlement behavior is measured. Furthermore, to find the set-up effect in H pile, No. 4, 16, 26, and R6 piles are restriked about 1, 2, and 14 days after driving. As results, ram height and pile capacity obtained from impact driving control method become 80cm and 210.3∼242.3ton, respectively. At 15 days after driving, allowable bearing capacity by CAPWAP analysis, which 2.5 of the factor of safety is applied for ultimate bearing capacity, increases 10.8%. Ultimate bearing capacity obtained from axially static load test is 306∼338ton. This capacity is 68.5∼75.7% at yield force of pile material and is 4∼4.5 times of design load. Allowable bearing capacity using 2 of the factor of safety is 153∼169ton. Initial stiffness response of the pile is 27.5ton/mm. As the lateral load increases, the horizontal load-settlement behaves linearly to which the lateral load reaches up to 17ton. This reason is filled with sand in the cavity formed between flange and web during pile driving. As the result of reading with electric strain gages, flange material of pile is yielded at 19ton in horizontal load. Thus allowable load of this pile material is 9.5ton when the factor of safety is 2.0. Allowable lateral displacement of this pile corresponding to this load is 23∼36mm in embankment.

• Journal of Periodontal and Implant Science
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• v.30 no.3
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• pp.675-687
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• 2000

Multiple periodontal pathogens sequentially colonize the subgingival niche during the conversion from gingivitis to destructive periodontal disease. An animal model of sequential immunization with key periodontal pathogens has been developed to determine whether T and B lymppocyte effector functions are skewed and fail to protect the host from pathogenic challenge. The present study was performed to evaluate immunomodulatory effect of exposure to Fusobacterium nucleatum(F. nucleatum) prior to Porphyromonas gingivalis(P. gingi - valis). Group 1(control) mice were immunized with phosphate-buffered saline, Group 2 were immunized with F. nucleatum prior to P. gingivalis, while Group 3 were immunized P. gingivalis alone. All the T cell clones derived from Group 2 demonstrated type 2 helper T cell clone(Th2 subsets), while those from Group 3 mice demonstrated Th1 subsets. Exposure of mice to F . nucleatum prior to P. gingivalis interfered with opsonophagocytosis function of sera against P. gingivalis. In adoptive T cell transfer experiments, in vivo protective capacity type 2 helper T cell clones(Th2) from Group 2 was significantly lower than type 1 helper T cell clones(Th1) from Group 3 against the lethal dose infection of P. gingivalis. Western blot analysis indicated the different pattern of recognition of P .gingivalis fimbrial proteins between sera from Group 2 and Group 3. In conclusion, these study suggest that colonization of the subgingival niche by F .nucleatum prior to the periodontal pathogen, P. gingivalis, modulates the host immune responses to P. gingivalis at humoral, cellular and molecular levels.

• Journal of Periodontal and Implant Science
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• v.30 no.3
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• pp.553-569
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• 2000

Many natural medicines have been studied for their capacity and effects of antibacterial, anti-inflammatory and regenerative potential in periodontal tissues. Safflower seed has been traditionally used as a drug for treatment of bone fracture in oriental medicine. The purpose of the present study was to compare the effects of safflower seed extract and bone substitute on bone formation and regeneration in artificial defects in mongrel dogs. The bony defects were made with round bur at mandible and tibia. Extracts of safflower seed and bovine bone were placed directly at each defect for experimental group, and the defect of control group was sutured without any other treatment. Experimental animals were sacrificed at 8 weeks. And then histopathologic reading and histomorphometric study was done. There was not significant differences between control and experimental groups in osteoclastic activity and infiltration of inflammatory cells. However, new capillary proliferation, fibrosis and new bone formation were prominent in safflower seed extract group. The mandibular defects of safflower seed extract group were healed with dense connective and bony tissues, and endochondral bone formation was observed in tibial defect of safflower seed extract group only. New bone area of safflower seed extract group was more significantly increased than that of control and that of bone substitute group. These results indicate that direct local application of safflower seed extracts on bony defects seems to reduces the early inflammatory response and to promotes the bone regeneration.