• Information and Communications Magazine
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• v.33 no.3
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• pp.36-45
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• 2016

LTE는 3GPP Rel-8부터 시작되어 현재 Rel-13까지 진화해오고 있으며 앞으로도 계속해서 진화할 것으로 예상된다. LTE는 단말의 이동성을 제공하면서 단말과 무선 접속 망 사이에 수십~수백 Mbps 급 고속의 패킷 통신이 가능하도록 하는 기술이며, LTE를 이용해서 서비스를 제공하기 위해서는 추가적으로 서비스 기술에 대한 표준화도 함께 고려가 되어야 한다. 공공안전사용기관인 주요 국가 정부를 중심으로 LTE을 공공안전용도로 사용 할 경우 최적 솔루션이 될 수 있음을 인지하고 3GPP 과제 제안을 통해, Rel-12부터 표준화를 시작하였다. 처음으로 표준화를 시작한 기술은 ProSe, D2D 및 GCSE이라는 기술이며, 2015년 3월에 완료되었다. 현재 진행 중인 Rel-13에서는 MCPTT, eProSe, eD2D, IOPS, MBMS_enh 기술에 대한 표준화가 진행 중이며 2016년 3월에 표준 완료 예정이다. 또한 2016년 3월부터는 Rel-14 표준화 기술로 선정된 MCVideo 및 MCData 표준화가 진행될 것으로 예상된다. 본 고에서 공공안전 용도로 특화되어 3GPP Rel-13 및 Rel-14에서 표준화가 진행되고 있는 주요 PS-LTE 기술의 표준화 현황과 계획에 대해 언급하고자 한다.

• Toxicological Research
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• v.23 no.1
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• pp.19-24
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• 2007

We demonstrate that paclitaxel, an antitumor agent derived from yew tree, inhibits LPS- and $IFN-{\gamma}$-induced NF-kB/Rel activation in RAW 264.7 cells. Previously, paclitaxel ($>10{\mu}M$) has been known to induce iNOS gene expression in macrophages. However, in the previous report we described that the pretreatment of macrophages with low concentration of paclitaxel ($0.1{\mu}M$) for 8 h inhibited LPS-induced iNOS gene expression. Pretreatment of RAW 264.7 cells with paclitaxel significantly inhibited NF-kB/Rel transcriptional activation. Electrophoretic mobility shift assay further confirmed that pretreatment of macrophages with paclitaxel inhibited NF-kB/Rel DNA binding. Taxotere, a semisynthetic analog of paclitaxel, also inhibited LPS- and $IFN-{\gamma}$-induced iNOS gene expression. Collectively, these series of experiments indicate that paclitaxel inhibits iNOS gene expression by blocking NF-kB/Rel activation.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.53 no.1
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• pp.43-55
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• 2004

This paper presents a study on evaluating the reliability indices considering a transmission system. Because successful operation of electric power under the deregulated electricity market depends on transmission system reliability management, quantity evaluation of transmission system reliability is very important. This paper introduces features and operation modes of the Transmission Reliability Evaluation for Large-Scale Systems(TRELSS) Version 6.0, a commercial program made in EPRI, and TranRel-I V3.2, a educational program made in GSNU(GyeongSang National University) for assessing reliability indices of composite power system. The packages access not only bulk but also bus indices for reliability evaluation of composite powers system. The practicality, effectiveness and future works of this methodology are illustrated by demonstrations of two case studies of modified IEEE 25 buses reliability test system using TRELSS and TranRel-I and a brief case study for the KEPCO size system using TranRel-II made in GSNU.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2004.05b
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• pp.221-224
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• 2004

By effect of infinity internet market copyright connection skills for extent extension of digital contents and profit rescue through this impoliticly research and develop. Contents protection techniques, management techniques, circulation techniques etc. are becoming development by contents circulation company and developers but that there is no standard as problem advances soul between copyright managerial system by development competition and in reciprocity compatibility tell. ISO MPEG commission arrived that develop MPEG-21 framework to solve problem that do that is to copyright management's opacity province that non efficiency and standard of contents distribution structure that do that is by redundancy investment are not. Data structure in Framework interior is doing and propose copyright expression language of XML base of REL to establish copyright connection data standard and normalized based on no XML. But, a tool that can be easy as must understand whole framework and can have problem in to edit REL and create copyright document fast was required. In this paper, research about method that edit REL document and develop and spend a edit tool that tan be that expressing intuitionally.

• Journal of Microbiology and Biotechnology
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• v.14 no.6
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• pp.1170-1175
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• 2004

The involvement of the relA and rsh genes in the morphological and physiological differentiation of Streptomyces clavuligerus was evaluated with the relA and rsh genes mutants. The morphological differentiation of S. clavuligerus was greatly affected by the disruption of the relA gene, but not very much by the disruption of the rsh gene. The altered morphological characteristics were completely restored by the complementation of the corresponding disrupted genes. Thus, it was apparent that the mycelial morphology and clavulanic acid production were severely affected by the disruption of the relA gene. Production of clavulanic acid in the submerged batch culture and glycerol-limited chemostat showed that production was inversely related to the specific growth rate in the wild-type strain. However, the production of clavulanic acid in the ${\Delta}relA$ and ${\Delta}rsh$ null mutants was completely abolished. Therefore, it seems plausible that the stringent response of S. clavuligerus to starvation for amino acids is governed mainly by ReIA, rather than Rsh, and that the (p)ppGpp synthesized immediately after the depletion of amino acids triggers the initiation of pathways for both morphological and physiological differentiation in this species.

• International Journal of Oral Biology
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• v.44 no.2
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• pp.31-36
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• 2019

Streptococcus mutans is one of the important bacteria that forms dental biofilm and cause dental caries. Virulence genes in S. mutans can be classified into the genes involved in bacterial adhesion, extracellular polysaccharide formation, biofilm formation, sugar uptake and metabolism, acid tolerance, and regulation. The genes involved in bacterial adhesion are gbps (gbpA, gbpB, and gbpC) and spaP. The gbp genes encode glucan-binding protein (GBP) A, GBP B, and GBP C. The spaP gene encodes cell surface antigen, SpaP. The genes involved in extracellular polysaccharide formation are gtfs (gtfB, gtfC, and gtfD) and ftf, which encode glycosyltransferase (GTF) B, GTF C, and GTF D and fructosyltransferase, respectively. The genes involved in biofilm formation are smu630, relA, and comDE. The smu630 gene is important for biofilm formation. The relA and comDE genes contribute to quorumsensing and biofilm formation. The genes involved in sugar uptake and metabolism are eno, ldh, and relA. The eno gene encodes bacterial enolase, which catalyzes the formation of phosphoenolpyruvate. The ldh gene encodes lactic acid dehydrogenase. The relA gene contributes to the regulation of the glucose phosphotransferase system. The genes related to acid tolerance are atpD, aguD, brpA, and relA. The atpD gene encodes $F_1F_0$-ATPase, a proton pump that discharges $H^+$ from within the bacterium to the outside. The aguD gene encodes agmatine deiminase system and produces alkali to overcome acid stress. The genes involved in regulation are vicR, brpA, and relA.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.6
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• pp.353-358
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• 2010

This study demonstrates the ability of magnolol, a hydroxylated biphenyl compound isolated from Magnolia officinalis, to inhibit LPS-induced expression of iNOS gene and activation of NF-${\kappa}B$/Rel in RAW 264.7 cells. Immunohisto-chemical staining of iNOS and Western blot analysis showed magnolol to inhibit iNOS gene expression. Reporter gene assay and electrophoretic mobility shift assay showed that magnolol inhibited NF-${\kappa}B$/Rel transcriptional activation and DNA binding, respectively. Since p38 is important in the regulation of iNOS gene expression, we investigated the possibility that magnolol to target p38 for its anti-inflammatory effects. A molecular modeling study proposed a binding position for magnolol that targets the ATP binding site of p38 kinase (3GC7). Direct interaction of magnolol and p38 was further confirmed by pull down assay using magnolol conjugated to Sepharose 4B beads. The specific p38 inhibitor SB203580 abrogated the LPS-induced NF-${\kappa}B$/Rel activation, whereas the selective MEK-1 inhibitor PD98059 did not affect the NF-${\kappa}B$/Rel. Collectively, the results of the series of experiments indicate that magnolol inhibits iNOS gene expression by blocking NF-${\kappa}B$/Rel and p38 kinase signaling.

• Communications of the Korean Mathematical Society
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• v.11 no.3
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• pp.815-823
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• 1996

M. Kontsevich posed a problem on mapping class groups of 3-manifold that is if M is a compact 3-manifold with nonempty boundary, then BDiff (M rel $\partial$ M) has the homotopy type of a finite complex. Here, Diff (M rel $\partial$ M) is the group of diffeomorphisms of M which restrict to the identity on $\partial$ M, and BDiff (M rel $\partial$ M) is its classifying space. In this paper we resolve the problem affirmatively in the case when M is a Haken 3-manifold.

• Information and Communications Magazine
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• v.28 no.6
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• pp.61-83
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• 2011

LTE-Advanced 표준 기술은 3GPP(3rd Generation Partnership Project) 에서 LTE 표준 기술의 후속 기술로 2008년 초부터 개발해오고 있는 기술이며, 차세대 이동통신 시스템의 국제 표준인 IMT-Advanced 표준 가운데 하나로 인준된 표준 기술이다. 현재, 최종 표준 완성을 목전에 두고 있는 상황이며, 완성된 표준에 대한 최종 ITU-R 표준 제출 과정이 진행 중에 있다. 본 고에서는 ITU-R의 IMT-Advanced 표준 발간 일정에 맞추어서 3GPP에서 진행해 온 논의 사항들에 대해 정리하고 또한 REL-10 LTE-Advanced 표준을 구성하고 있는 주요 요소 기술들에 대해 알아본다. 마지막으로 LTE-Advanced 기술에 대한 향후 표준화 방향 등에 대하여 알아본다.

• BMB Reports
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• v.35 no.6
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• pp.537-546
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• 2002

NF-${\kappa}B$/Rel transcription factor family participates in diverse biological processes including embryo development, hematopoiesis, immune regulation, as well as neuronal functions. In this review, the NF-${\kappa}B$/Rel signal transduction pathways and their important roles in the regulation of immune system will be discussed. NF-${\kappa}B$/Rel members execute distinct functions in multiple immune cell types via the regulation of target genes essential for cell proliferation, survival, effector functions, cell trafficking and communication, as well as the formation of lymphoid architecture. Consequently, proper activation of NF-${\kappa}B$/Rel during immune responses to allergens, auto-antigens, allo-antigens, and pathogenic infection is crucial for the integrity of host innate and adaptive immunity.