• The Journal of the Korea Contents Association
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• v.20 no.4
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• pp.159-168
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• 2020

This study aims to utilize DEA, analyze the efficiency of Korean coffee franchises, look into the factors that affect efficiency, and improve the efficiency of Korean coffee franchises. The main results of this study are as follows. First, according to CCR model standards, there are a total of 9 efficient coffee franchises and according to BCC model standards, there are a total of 12 efficient coffee franchises. A total of three of the inefficient DMUs were found to have a value of 1 for BCC, while the other 25 were found to be inefficient for both technology and scale. Second, of 28 franchises, 11 were analyzed to be decreasing return to scale and through future increased investments of optimum levels, business performance can be improved and efficiency can be enhanced. Analysis showed that 9 franchises appeared as CRS and it is most ideal to maintain the yield of future output elements at current levels and the work efficiency of 8 franchises in increasing returns to scale states expands as production scales increase according to specialization and role division and yield can relatively improve a lot. Third, the analysis of factors affecting the efficiency of franchises through the Tobit regression analysis showed that the number of franchises and operating periods had a positive (+) effect on efficiency. Based on this study, the efficiency of coffee franchises should be analyzed to establish strategies to maximize efficiency. Based on this study, the efficiency of coffee franchises should be analyzed to establish strategies to maximize efficiency.

• Journal of Microbiology and Biotechnology
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• v.27 no.4
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• pp.701-708
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• 2017

This study was conducted to evaluate the hyaluronidase (HAase) inhibition activity of Asparagus cochinchinesis (AC) extracts following fermentation by Weissella cibaria through response surface methodology. To optimize the HAase inhibition activity, a central composite design was introduced based on four variables: the concentration of AC extract ($X_1$: 1-5%), amount of starter culture ($X_2$: 1-5%), pH ($X_3$: 4-8), and fermentation time ($X_4$: 0-10 days). The experimental data were fitted to quadratic regression equations, the accuracy of the equations was analyzed by ANOVA, and the regression coefficients for the surface quadratic model of HAase inhibition activity in the fermented AC extract were estimated by the F test and the corresponding p values. The HAase inhibition activity indicated that fermentation time was most significant among the parameters within the conditions tested. To validate the model, two different conditions among those generated by the Design Expert program were selected. Under both conditions, predicted and experimental data agreed well. Moreover, the content of protodioscin (a well-known compound related to anti-inflammation activity) was elevated after fermentation of the AC extract at the optimized fermentation condition.

• Korean Journal of Remote Sensing
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• v.36 no.5_1
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• pp.785-791
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• 2020

The radiance measured from satellite has noise due to atmospheric effect. Atmospheric correction is the process of calculating surface reflectance by removing atmospheric effect and surface reflectance is calculated by the Radiative Transfer Model (RTM)-based Look-Up Table (LUT). In general, studies using a LUT make LUT for each channel with the same atmospheric and geometric conditions. However, atmospheric effect of atmospheric factors do not react sensitively in the same channel. In this study, the LUT for each channel of Korea Multi-Purpose SATellite (KOMPSAT)-3/3A was made under the same atmospheric·geometric conditions. And, the accuracy of the LUT was verified by using the simulated Top of Atmosphere radiation and surface reflectance in the RTM. As a result, the relative error of the surface reflectance in the blue channel that sensitive to the aerosol optical depth was 81.14% at the maximum, and 42.67% in the NIR (Near Infrared) channel.

• Journal of Life Science
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• v.19 no.10
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• pp.1360-1367
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• 2009

Liver fibrosis is a process of healing and scarring in response to chronic liver injury. Following injury, an acute inflammation response takes place resulting in moderate cell necrosis and extracellular matrix damage. To develop a novel therapeutic approach in hepatic fibrogenesis, we examined the simultaneous suppression of the transcription factors NF-$\kappa$B and Sp1, which regulate acute inflammation and continuous deposition of extracellular matrix in liver fibrosis. We employed chimeric decoy oligodeoxynucleotide containing the consensus sequences of both NF-$\kappa$B and Sp1 binding sites, to suppress these transcription factors simultaneously. Treatment of chimeric decoy oligodeoxynucleotide reduced the activity of hepatic stellate cells in vitro, and decreased the expression of fibrotic and proinflammatory gene responses in a mouse model of liver fibrosis. These results suggest that chimeric decoy oligodeoxynucleotide strategy can be a potential therapeutic application to prevent liver fibrosis.

• Journal of Wetlands Research
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• v.13 no.1
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• pp.95-104
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• 2011

This study was implemented to select the suitable site for Palustrine Wetland at habitat restoration for Oriental stork, red species and top-level predator in ecosystem. The evaluation items was fitted by review the antecedent studies on the suitable site selection model and evaluation items of wetland. The study sites were setted in $5,884,800m^2$ area including Yesan-gun Dae-ree, in which Oriental stork' park will be located, through DEM(Digital Elevation Model) watershed analysis. The thematic map by valuation items with secure of water resource, soil, topography, distance between roads, houses, etc., land using, wildlife corridor, and type of water resource was prepared using GIS program. The sites with high evaluation score were selected as suitable creation sites for wetland through overlapping those maps. Total 8 sites with over 18 point were selected. The characteristics of selected sites show that the soil are consisted of clay, the connectivity is valued high with surface water, the slope are gentle, and the connectivity is good with surroundings ecosystem. The result of water quality analysis, which was implement to survey available water resources and develop the solution of problem of water environment, showed that water quality at Salmok reservoir and Bogang reservoir is generally good, but the water quality at stagnant water body rising out from groundwater is not good. This study has limit to select the suitable sites of wetland only by analyzing physiotherapy environment in study area. Hereafter, the study is need to examine closely enhancement effects of biological diversity through investigation of biotic environment.

• Imaging Science in Dentistry
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• v.43 no.1
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• pp.7-15
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• 2013

Purpose: This study was performed to suggest reference line-pair values of panoramic images with clinically desirable qualities using an arch-form phantom stand. Materials and Methods: The line-pair test phantom was chosen. A real skull model was selected for setting the arch-form model of the phantom stand. The phantom stand had slits in four regions (incisor, premolar, molar, TMJ). Four raw images of the test phantom in each region and one raw image of the real skull were converted into 50 test phantom images and 50 skull phantom images with various line-pair values. 50 post-processed real skull phantom images were divided into 4 groups and were randomly submitted to 14 evaluators. Image quality was graded on a 4 point scale (1. good, 2. normal, 3. poor but interpretable, and 4. not interpretable). The reference line pair was determined as the first line-pair value scored less than 2 points. Result: The mean scores tended to decrease as the line-pair values increased. The reference line-pair values were 3.19 LP/mm in the incisor, 2.32 LP/mm in the premolar and TMJ, and 1.88 LP/mm in the molar region. Conclusion: Image quality evaluation methods and criteria should be able to assess various regions considering the characteristics of panoramic systems. This study suggested overall and regional reference line-pair values and established a set of standard values for them.

• Journal of Life Science
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• v.20 no.5
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• pp.799-804
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• 2010

In humans, CYP2C19, a member of the cytochrome P450 subfamily, metabolizes arachidonic acid to produce epoxyicosanoid acids, which are involved in vascular tone and regulation of blood pressure (BP). Recent findings suggest that CYP2C19 gene polymorphisms might be considered as a novel candidate gene for cardiovascular disease. We thus focused on the Korean population to explore the association of two polymorphisms ($CYP2C19^*2$ and $^*3$) in this gene and essential hypertension (EH). A total of 1,241 participants (537 hypertensive subjects and 704 healthy controls) were recruited from the Yonsei Cardiovascular Genome Center in Korea. The CYP2C19 polymorphisms were genotyped using the $SNaPShot^{TM}$ assay. The allele and genotype frequencies of $CYP2C19^*3$ showed significant difference between hypertensives and normotensives (P=0.019 and P=0.023, respectively). Logistic regression analysis indicated that the $CYP2C19^*3$ A allele carriers were significantly associated with EH (OR, 0.723; 95% CI, 0.538-0.972, P=0.032) under a dominant model. In addition, CYP2C19 G-A haplotype ($2C19^*2\;G-^*3$ A combination) was found to significantly reduce EH risk (OR, 0.714, P=0.015). We believe this provides evidence that $CYP2C19^*3$ polymorphism may contribute to a protective effect in the development of EH.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.2
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• pp.83-94
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• 2019

Recently, the importance of Total Life Cycle System Management (TLCSM) and LIFE-CYCLE COSTS management is increasing in the development of weapon systems. In cost management, cost forecasting is important from the initial development stage, but it is difficult to predict the total life cycle cost at the development stage. In this study, we propose efficient management cost calculation and management at the development stage of the weapon system by comparison analysis between the PRICE-HL model and NemoSIM to calculate the maintenance cost under the CAIV concept. Based on the study results, further in-depth analyzes of the PRICE-HL model and NemoSIM input values / results are performed. In addition, we provide a more accurate method of calculating the cost of maintaining and operating the weapon system and a plan to utilize the result of NemoSIM in the ILS element development.

• Laboraroty Animal Research
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• v.34 no.4
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• pp.223-231
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• 2018

Regulation of gastrointestinal hormones have been reported in animal models for constipation undergoing laxative therapy when administered herbal products. We undertook to investigate whether the laxative activity of gallotannin-enriched extracts isolated from Galla Rhois (GEGR) affects the regulation of gastrointestinal hormones, by examining the concentration of four hormones and the activation of their receptors in the loperamide (Lop)-induced constipation model. Stool parameters, including number, weight and water content, were significantly recovered in the Lop+GEGR treated group, relative to the Lop+ vehicle treated group; however, food intake and water consumption were maintained at a constant level. Also, a similar recovery was detected for thickness of mucosa, muscle and flat luminal surface in the Lop+GEGR treated group. Furthermore, concentration of the four gastrointestinal hormones evaluated, namely, cholecystokinin (CCK), gastrin (GAS), somatostatin (SS) and motilin (MTL), were lower in the Lop+vehicle treated group than the No treated group, but were remarkably enhanced in the Lop+GEGR treated group. Moreover, the downstream signaling pathway of MTL and SS receptors were recovered after GEGR administration. Results of the present study therefore indicate that the laxative effects of GEGR treatment may be tightly related with the regulation of gastrointestinal hormones in the Lopinduced constipation model.

• The Journal of the Korea Contents Association
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• v.21 no.2
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• pp.227-235
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• 2021

The purpose of this study was to investigate the association factors of dental infection control by applying the health belief model in the dental hygienists. This study subject was 142 dental hygienists from 15 to July 5, 2020. Data were analyzed by chi-square test ANOVA, correlation analysis, and multiple regression analysis using SPSS version 23.0. The performance of dental infection control in accordance with the general characteristics of research subjects was high in case when they had educational experiences of infection control, and when they 'always' did medical examinations by interview about infectious diseases(p<0.01). The group of dental hygienists working for dental clinics with less than average 50 patients a day showed the highest rate of wearing a mask and latex gloves as personal protective gears(p<0.05),(p<0.01). When the wearing of protective goggles(face shield) and the frequency of exchanging masks after the outbreak of COVID-19 were more, the performance for infection control was increasing(p<0.05),(p<0.01),(p<0.001). In this study, it is difficult to generalize the results of the study because the research area and the subject are limited by selecting the subjects by convenience extraction, and focusing on the degree of awareness of infection control by dental hygienists, the actual status of infection control in dentistry is carefully illuminated. What you didn't do can be seen as a limitation. Considering the results of this study, the performance of infection control could be increased by removing obstacles and increasing the importance and perceived benefits of infection control of dental hygienists.