• The Korea Journal of Herbology
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• v.34 no.6
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• pp.139-146
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• 2019

Objective : Recently, hair has become one of the important aspects of beauty. So, there are many studies about prevention and treatment of alopecia. Finasteride and minoxidil have been known to drug for alopecia treatment. However, these agents have side effects such as irritation, pruritus, and erythema when they were used for a long time. So, we assessed hair growth effect on herbal mixture (RAA) include in Rehmanniae Radix Preparata, Achyranthis Radix, and Acanthopanacis Cortex. Methods : 6 weeks aged C57BL/6 mice were divided three treatment groups. : CON group (vehicle solution), MNXD group (positive control, 3% minoxidil), RAA group (15% RAA solution). And we applied 200 ㎕ of three groups to shaved dorsal skin every day. Hair growth effects of treatment were determined through phototrichogram by folliscope and hair follicle morphometry by H&E staining. And we assessed hair growth-related gene (VEGF, IGF-1, TGF-β1) expressions by western blot and 5-α reductase II analysis of dermal (skin) or internal organ (prostate gland). Results : Hair density and hair follicle size in MNXD or RAA group was enhanced compared to those of CON group, respectively. Also, the protein expression levels in dermal of VEGF, IGF-1 increased but TGF-β1 decreased in RAA and MNXD group, compared to CON group, respectively. 5-α reductase II levels of tissues in MNXD or RAA group significantly decreased compared to those of CON group, respectively. Conclusion : These results suggest that RAA has the promoting effect on hair growth.

• Parasites, Hosts and Diseases
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• v.60 no.3
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• pp.201-205
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• 2022

Babesia microti is one of the most common causative agents of babesiosis. A sensitive and rapid detection is necessary for screening potentially infected individuals. In this study, B. microti cytochrome c oxidase subunit I (cox1) was selected as the target gene, multiple primers were designed, and optimized by a recombinase-aided amplification (RAA) assay. The optimal primers and probe were labeled with fluorescein. The sensitivity of fluorescent RAA (fRAA) was evaluated using gradient diluents of the cox1 recombinant plasmid and genomic DNA extracted from whole blood of B. microti infected mice. The specificity of fRAA was assessed by other transfusion transmitted parasites. The analytical sensitivity of the fRAA assay was 10 copies of recombinant plasmid per reaction and 10 fg/µl B. microti genomic DNA. No cross-reaction with any other blood-transmitted parasites was observed. Our results demonstrated that the fRAA assay would be rapid, sensitive, and specific for the detection of B. microti.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.21 no.4
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• pp.381-391
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• 2010

In this paper, a novel frequency reconfigurable active array antenna(RAA) system, which can be reconfigurable for three reconfigurable frequency bands, is proposed by using commercial RF MEMS switches. The MEMS switch shows excellent insertion loss, linearity, as well as isolation. So, the system performance degradation of the reconfigurable system by using MEMS switches can be minimized. The proposed frequency reconfigurable active antenna system is consisted with the noble frequency reconfigurable front-end amplifiers(RFA) with the simple reconfigurable impedance matching circuits(RMC), reconfigurable antenna elements(RAE), as well as a reconfiguration control board(RCB) for MEMS switch control. The proposed RAA system can be reconfigurable for three frequency bands, 850 MHz, 1.9 GHz, and 3.4 GHz, with $2{\times}2$ array of the RAE having broadband printed dipole antenna topology. The validity of the proposed RFA as well as RAA is also presented with the experimental results of the fabricated systems.

• Journal of the Korean Society of Marine Environment & Safety
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• v.25 no.2
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• pp.159-168
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• 2019

This study was designed to investigate the physiological response of humans to alcohol during underwater activity and to complete related risk analysis. After comparing human responses to alcohol during underwater activity, we analyzed physiological changes and risk level using a new risk analysis method developed in this study, 'Risk Assessment and Analysis (RAA)'. RAA is a modified method based on an internal control frame work. It has 3 steps, the first of which is to analyze risk correlation. The second step is to quantify risk and build a risk database. The last step is to analyze the diagramed risk map. Using RAA, the risk levels of alcohol use underwater were calculated and diagramed. The diagramed risk map was then used to analyze the difference between risk levels underwater before and after alcohol use. As a result, it was found that risk level underwater increased after alcohol use. This study shows alcohol use increases the ratio of high risk groups during underwater activity. It also indicates that risk levels can be quantified according to the likelihood and impairment scale, which can potentially help in identifying high risk groups for intensive management underwater.

• KOREAN POULTRY JOURNAL
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• v.40 no.12
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• pp.134-137
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• 2008

본고는 2008년 10월 RAA(로스아시아협의회의)에서 일본로스원종계 회사(Nippon Chunky Co. Ltd)의 Thoshiaki Ohtsuki가 발표한 자료를 근거로 작성한 것이다. 일본은 우리나라와는 기후가 매우 흡사하고 같은 종의 닭을 사육함에도 불구하고 육계산업의 생산성은 우리나라보다 훨씬 우월하여 우리나라에서 업계에 종사하는 분들에게 이웃 나라 일본의 생산성과 비교해 보면서 생산성 향상 노력에 조금이나마 도움이 되고자 하는 바람으로 이 글을 쓴다.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.21 no.8
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• pp.1581-1588
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• 2017

Recently, circulating ransomware is becoming intelligent and sophisticated through a spreading new viruses and variants, targeted spreading using social engineering attack, malvertising that circulate a large quantity of ransomware by hacking advertising server, or RaaS(Ransomware-as-a- Service), from the existing attack way that encrypt the files and demand money. In particular, it makes it difficult to track down attackers by bypassing security solutions, disabling parameter checking via file encryption, and attacking target-based ransomware with APT(Advanced Persistent Threat) attacks. For remove the threat of ransomware, various detection techniques are developed, but, it is very hard to respond to new and varietal ransomware. Accordingly, in this paper, find out a making Signature-based Detection Patterns and problems, and present a pattern automation model of ransomware detecting for responding to ransomware more actively. This study is expected to be applicable to various forms in enterprise or public security control center.

• Resources Recycling
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• v.16 no.6
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• pp.20-27
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• 2007

This paper presents a detailed experimental study on the durability properties of mortar matrix made with two kind of recycled fine aggregates(RAA, RAB) and five replacement levels (0, 25, 40, 75 and 100) of the recycled fine aggregates as a partial replacement of natural fine aggregate (NA). The durability properties of mortar matrix was evaluated using compressive strength, chloride ion ingress, sulfate attack and carbonation. The test results indicated that the water absorption and Adhered mortar of the recycled fine aggregate was a major factor controlling durability properties. Hereafter, when using built recycled fine aggregate is expected, appropriate removal Adhered mortar and reasonable replacement ratio of recycled fine aggregates was 25% weight of cement are advised to apply to the concrete materials.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.4
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• pp.37-43
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• 2005

Real time monitoring of exit burr formation is critical in manufacturing automation. In this paper, acoustic emission (AE) was used to detect the burr formation during drilling. By using wavelet transform (WT), AE data were compressed without unnecessary details. Then the transformed data were used as selected features (inputs) of a back-propagation artificial neural net (ANN). In order to validate the in process AE monitoring system, both WT-based ANN and cutting condition (cutting speed, feed, drill diameter, etc.) based ANN outputs were compared with experimental data.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.30 no.1 s.244
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• pp.1-7
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• 2006

A system for the electrical bio signal detection for a microchip is proposed. Gold nanoparticles were selected for the system for their bio-compatibility and potential for higher sensitivity with large surface areas. For the estimation of the conductivity of gold nanoparticles, microchips with interdigitated microelectrodes of 3,5,7 and $9\;{\mu}m$ spacing were fabricated. In addition, a simulation program was developed to estimate the electrical resistance of the fabricated microchip. The results of conduction simulation for the nanoparticles show good agreements with experimental data, which validate the proposed system.

• Korean Journal of Microbiology
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• v.39 no.3
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• pp.166-174
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• 2003

Microcystin produced by cyanobacteria in surface waters, such as eutrophic lake and river, is a kind of serious environmental problems due to its toxicity to human and wild animals. Microcystin is synthesized nonribosomally by the large modular multi-functional enzyme complex known as microcystin synthetase encoded by the mcy gene cluster. Amplification of mcy genes by PCR from cultures and environmental samples is a simple and efficient method to detect the toxigenic Microcystis. In order to evaluate primers designed to detect toxic microcystin-producing strains, 17 cyanobacterial strains and 20 environmental samples were examined by PCR with 7 pairs of primers. Some microcystin-producing cyanobacteria were not detected with FAA-RAA, TOX4F-TOX4R and FP-RP primers. The fragment of unexpected size was amplified with NSZW2-NSZW1 primers in Microcystis strains isolated from the lakes in Korea. TOX1P-TOX1F primers failed in amplification of toxin-producing strains. Only MSF-MSR and TOX2P- TOX2F primers amplified the fragments of mcy genes from 11 strains of microcystin-producing Microcystis. The water samples taken from 20 lakes in Korea were analyzed by PCR using each of the primers. In all the water samples, cyanobacteria capable of producing microcystin were detected by the PCR with TOX2P-TOX2F primers. These results indicate that TOX2P-TOX2F primers are better than the other primers for detection of microcystin-producing Microcystis strains in Korea. The nucleotide sequences of mcy gene in Microcystis aeruginosa NIER10010 suggest genetic diversity of Korean isolates.