• 제목/요약/키워드: R170

검색결과 530건 처리시간 0.025초

클러치 마스터 실린더의 성능최적화에 관한 연구 (Study on Performance Optimization of Clutch Master Cylinder)

  • 이춘곤;이창헌;변재혁;이재열;노승훈;이종형
    • 한국산업융합학회 논문집
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    • 제11권4호
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    • pp.165-170
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    • 2008
  • The demand for the lighter parts compels new composite materials composed of nylon66 and glass fiber to be used for the clutch control hydraulic system to achieve the low cost, light weight and the simple production process. In this paper the feasibility of using those composite materials for the clutch system has been investigated. And the efforts have been concentrated to enhance the durability and the credibility of the system. The procedure has been developed to design the clutch system to satisfy the categories mentioned above and to analyze the durability of the system and to setup a simulation program for the realistic driving situations.

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Purification and Characterization of Quercitrin-Hydrolyzing ${\alpha}$-L-Rhamnosidase from Fusobacterium K-60, a Human Intestinal Bacterium

  • PARK SUN-YOUNG;KIM JOO-HYUN;KIM DONG-HYUN
    • Journal of Microbiology and Biotechnology
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    • 제15권3호
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    • pp.519-524
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    • 2005
  • An ${\alpha}$-L-rhamnosidase (EC 3.2.1.40.), which transforms quercitrin to quercetin, was purified from Fusobacterium K-60, a human intestinal anaerobic bacterium. The specific activity of the purified ${\alpha}$-L-rhamnosidase was 2.89 mol/min/mg protein. ${\alpha}$-L-Rhamnosidase, whose molecular size was 170 kDa by gel filtration, was composed of four subunits ($M_r$ 41,000 Da) with pI and optimal pH values of 5.2 and 5.5-7.0, respectively. The apparent $K_m$ and $V_{max}$ values for p-nitrophenyl-${\alpha}$-L-rhamnopyranoside and quercitrin were determined to be 0.057 mM and 3.4 mol/min/mg, and 0.077 mM and 5.0 mol/min/mg, respectively. This enzyme was strongly inhibited by $Cu^{2+},\;Mn^{2+}$, L-rhamnose, and p-chlormercuriphenylsulfonic acid. These findings suggest that the biochemical properties and substrate specificity of the purified enzyme are different from those of the previously purified ${\alpha}$-L-rhamnosidase. This is the first reported purification of quercitrin-hydrolyzing ${\alpha}$-L-rhamnosidase from intestinal bacteria.

간호대학생의 노인에 대한 지식, 태도 및 행동에 대한 연구 (A Study on the Nursing Students' Knowledge, Attitudes and Behavior towards the Elderly)

  • 김수옥;오효순;왕미숙
    • 한국간호교육학회지
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    • 제22권2호
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    • pp.163-170
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    • 2016
  • Purpose: The purpose of this study is to determine the relationship between nursing students' level of knowledge of and attitude toward the elderly and their behavior towards the elderly. Methods: For this study, 223 nursing students participated. The data was analyzed with PASW statistics program version 18.0 using descriptive statistics, a t-test, one-way ANOVA, Pearson's Correlation coefficient and multiple regression analysis. Results: The findings of the study displayed a score of 14.5 out of 25 for the level of knowledge of the elderly, a score of 3.9 out of 7 on the attitude toward the elderly, and 1.3 points on a 4-point scale on behavior towards the elderly. There was a positive correlation (r=.410, p<.001) between attitude and behavior towards the elderly, thus confirming that attitude towards the elderly influences behavior towards them. Conclusion: The most influential variable on the behavior towards the elderly emerged to be attitude. Thus, although knowledge and attitude cannot be neglected in manifesting positive behaviors in nursing students when they care for the elderly, knowledge training and elderly nursing practical sessions need to take place in order to strengthen attitude, which displayed a positive correlation with behavior.

Structure and Vorticity of the Current Observed Across the Western Channel of the Korea Strait in September of 1987-1989

  • Byun, Sang-Kyung;Kaneko, Arata
    • Ocean and Polar Research
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    • 제21권2호
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    • pp.99-108
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    • 1999
  • With sectional data obtained in September of 1987, 1988 and 1989 by quadrireciprocal ADCP measurement and CTD cast, the current structure, volume transport and vorticity in the Western Channel of the Korea Strait were studied. The characteristics of Tsushima Current water persisted throughout the summer especially in the homogeneous water of temperature $14-16^{\circ}C$ located at the depth of 50-100m below seasonal termocline. Thickness and velocity of the homogeneous layer are about 10-170m and 20-60cm/s. and the relative vorticity for this layer is shown to be nearly constant and it is smaller than the planetary vorticity. Potential vorticity of $2.70-7.10{\times}10^{-6}m^{-1}s^{-1}$ is found to be dependent mainly on planetary rather than on the relative vorticities. The Tsushima Current water represented by the homogeneous layer R14-16^{\circ}C$ may keep the potential vorticity at the area of strong current in the Strait. The ADCP current structure is similar to geostrophic current and the core of the current with the speed of 30-50cm/s is situated in the middle layer over the deep trough. With large tidal fluctuation the volume transport has mean value of 1.17sv which was about 40% larger than that of geostrophic calculation.

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착상조건 하에서 핀-관 열교환기의 성능예측을 위한 컴퓨터 시뮬레이션 (A Computer Simulation for Performance Prediction of Fin-Tube Heat Exchanger under Frosting Conditions)

  • 이관수;박희용;이욱용;이태희;이수엽;이명렬
    • 설비공학논문집
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    • 제7권1호
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    • pp.161-170
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    • 1995
  • This study is concerned with the numerical analysis of performance on fin-tube heat exchanger under frosting condition. In this work, tube-by-tube method using LMED is employed. The present results are compared with O'Neal's experimental and numerical results. A standard evaporator model with 2rows-2columns is selected to investigate the effects of the various parameters such as fin pitch, air flow velocity, and humidity. The results show that frost thickness and the amount of frost per unit area decrease as fin-pitch becomes narrower. In the meantime, frost thickness and accumulation rate increase with higher inlet air humidity. It is shown that heat transfer rate increases during 30minutes and then it decreases. Heat transfer rate and the amount of frost increase with air velocity, however frost thickness does not increase over a certain velocity.

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Cyclic Nucleotide Phosphodiesterases as Possible Targets for Ginsenosides

  • Lugnler, C.;Kim, N.D
    • 고려인삼학회:학술대회논문집
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    • 고려인삼학회 1998년도 Advances in Ginseng Research - Proceedings of the 7th International Symposium on Ginseng -
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    • pp.216-223
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    • 1998
  • Cyclic nucleotide phosphodiesterases (PDEs) represent the unique enzymatic system degrddinf cAMP and cGMP which play a major role in the regulation of cell physiology. To investigate a possible molecular mechanism of ginsenosides, their activities were evaluated on PDEs which are recently described is new therapeutic targets. PDEs are classified into 7 families according to their genes (PDEI to PDE7) and are differently distributed in tissues. The IC50 values of ginsenosides were determined on PDEI to PDE 5 chromatographically isolatetl from bovine aorta. The results show that total ginseng saponin extract preferentially inhibits PDE 1 and PDE4 at concentrations nearby 200 ug/ml. Protopanaxadiol (PPD) fraction acts preferentially on PDE4 with and IC50 value of 100 nlml and inhibits also PDEI and PDE5 at 14 to 2 fold higher concentrations, respectively. Protopanaxatriol (PPT) fraction preferentially inhibits PDE 1 with and IC50 value of 170 ug/ml. Compound Rgl, originated from PPT fraction, and RC3 (5) represent the most active compounds towards PDE 1 with IC50 values around 80 UM. However Rg3 (R), epimer of Rgl (5) has no effect on the various PDEs tested, excepted on PDE3 rich is sligthly sensitive Compound Rbl, originated from PPD, acts on both PDEI and PDE4. It if two fold less active than Rgl and Rg3 (5) on PDEI. Taken together, these results mainly suggest that PDEI and PDE4 inhibitions could be a molecular mechanism which would participate in ginsenoside mechanisms, especially the effect of PPD on blood vessel and on CNS.

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응급실 간호사의 외상사건 경험, 공감피로, 자아존중감, 공감만족 및 소진 (Effects of Traumatic Events, Compassion Fatigue, Self-esteem, and Compassion Satisfaction on Burnout of Nurses in Emergency Department (ED))

  • 전연진;성미혜
    • 한국직업건강간호학회지
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    • 제23권2호
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    • pp.80-88
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    • 2014
  • Purpose: The purpose of this study is to verify the factors that determines burnout of nurses in emergency department. Methods: The survey was given to 170 ED nurses which are located in Busan from July 1st to August 31st of 2012. The results were analyzed by descriptive statistics, t-test, ANOVA, pearson correlation coefficients and stepwise multiple regression using SAS 9.2 program. Results: There were statistically significant differences in burnout depending on gender, position, workplace satisfaction, job satisfaction. Significant positive correlation between compassion fatigue and burnout was found. Also significant negative correlation was found between self-esteem, compassion satisfaction and burnout. Factors influencing burnout were self-esteem, compassion satisfaction and compassion fatigue with $R^2$ value 58.0%. Conclusion: Considering these results, it seems that great efforts will be needed for reducing burnout by mitigating the emergency nurses' compassion fatigue and introducing programs to increase the self-esteem and compassion satisfaction.

Turbomachinery design by a swarm-based optimization method coupled with a CFD solver

  • Ampellio, Enrico;Bertini, Francesco;Ferrero, Andrea;Larocca, Francesco;Vassio, Luca
    • Advances in aircraft and spacecraft science
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    • 제3권2호
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    • pp.149-170
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    • 2016
  • Multi-Disciplinary Optimization (MDO) is widely used to handle the advanced design in several engineering applications. Such applications are commonly simulation-based, in order to capture the physics of the phenomena under study. This framework demands fast optimization algorithms as well as trustworthy numerical analyses, and a synergic integration between the two is required to obtain an efficient design process. In order to meet these needs, an adaptive Computational Fluid Dynamics (CFD) solver and a fast optimization algorithm have been developed and combined by the authors. The CFD solver is based on a high-order discontinuous Galerkin discretization while the optimization algorithm is a high-performance version of the Artificial Bee Colony method. In this work, they are used to address a typical aero-mechanical problem encountered in turbomachinery design. Interesting achievements in the considered test case are illustrated, highlighting the potential applicability of the proposed approach to other engineering problems.

염해 환경에 있는 지하철 콘크리트 구조물의 내구성 향상 대책수립에 관한 연구 (A Study for Development of Durability of the Subway Concrete Structure exposed to Choride Environment)

  • 이무관;김은겸;김대호
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2005년도 추계학술대회 논문집
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    • pp.1184-1189
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    • 2005
  • Durability of concrete has been currently issued in the engineering societies and a large number of studies on the concrete corrosion in salty environment have been performed. The reinforcement corrosion, which is the primary reason of deterioration of the concrete structure exposed to chloride environment. is caused by the chloride ions infiltration owing to underground water seeping into the concrete. In this study. the endurance periods using the diffusion equation of the concrete specification have been evaluated on the concrete structures with different addictives for the brand new R/C subway structure exposed to seashore underground water. Furthermore. the guidance for proper use of the addictives and the reasonable thickness of concrete cover are derived for concrete mixing. From the result of the evaluation corresponding to salt damage for Inchon subway line I, the endurance periods of the ordinary Portlandcement concretes are represented as $42\~75$ years and fail to achieve the objective period of 100 years. However, the lower water-cement ratio expands the endurance periods and the blast furnace slag concrete with small quantity of the silica fume, which shows the best performance of corrosion resistance in this study, represents more than 170 years of the endurance period. Moreover, the case of use of blast furnace slag and fly ash together shows the endurance period of $134\~171$ years and it means that the result very satisfies the objective endurance period.

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메르스 감염 유행 후 상급종합병원 간호사의 외상 후 스트레스 영향요인 (Factors Affecting Post-Traumatic Stress of General Hospital Nurses after the Epidemic of Middle East Respiratory Syndrome Infection)

  • 김현진;박호란
    • 임상간호연구
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    • 제23권2호
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    • pp.179-188
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    • 2017
  • Purpose: This study examined post-traumatic stress (PTS) and the factors affecting it among general hospital nurses after the MERS(Middle East Respiratory Syndrome) epidemic. Methods: Data were collected from 170 nurses who worked at general hospitals since the first reported MERS outbreak. The IES-R-K assessed PTS. Data were analyzed using SPSS. Results: The mean PTS level was 7.80 points (range: 0~88); 7.1% of the participants were at a high risk. Nurses who had been in contact with patients suspected or diagnosed with MERS had high post-traumatic levels; those who had been quarantined during the MERS outbreak had relatively higher PTS levels. Shift-work nurses had higher PTS levels than those with fixed working hours. Above charge' nurses stress levels were higher than staff nurses' stress levels. The results showed that factors including contact with an MERS-suspected or diagnosed patient, position at work, and working status of MERS-affected nurses explained 16% of the PTS. Among the main variables, nurses' above charge position was the greatest factor affecting PTS. Discussion: It is necessary to develop intervention studies and programs considering these variables. Furthermore, development and implementation of differentiated programs should be done considering the position of above charge nurses.