• Journal of Adhesion and Interface
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• v.18 no.4
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• pp.166-170
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• 2017

In this study, acrylic rubber pressure sensitive adhesives was polymerized with 2-ethylhexyl acrylate, styrene, butadiene, 2-hydroxyethyl acrylate, and acrylic acid by controlling the initiator content. The initial tackiness, peel strength, holding power, and heat resistance of the PSAs were investigated by changing the content of tackifier and curing agent. The results showed that the initial tackiness and peel strength increased as the content of tackifier increased, whereas the holding power decreased. Also, the results exhibited that that the initial tackiness, peel strength, and heat resistance decreased as the content of curing agent increased, whereas the holding power and decreased.

• Journal of Convergence for Information Technology
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• v.9 no.11
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• pp.159-170
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• 2019

This study examined the influence of academic self-efficacy of Faculty-student inter action and peer relations. The subject were collected from 289 dental hygiene students J region, three colleges of between November 5, December 30, in 2018. The data was analyzed by descriptive, pearson correlation coefficient and multiple regression. Faculty-student interact ion was correlated with peer relations(r=.434) and had a positively correlation with academic self-efficacy(r=.282) with improved of major satisfaction and higher academic performance, a much more vigorous active faculty-student interaction and peer relations of level of academic self-efficacy. The results reveals to develop program co-relationship in order to improve academic self-efficacy.

• Journal of Korean Clinical Health Science
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• v.8 no.2
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• pp.1450-1461
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• 2020

Purpose: The purpose of this study was to understand the degree of nursing professional intuition, major satisfaction, clinical practice satisfaction, self-leadership, and career preparation behavior of nursing college students, and to identify factors that influence career preparation behavior. Method: This study was a descriptive research study to analyze the factors affecting career preparation behavior. The data collection period was from August 03 to 30, 2020 for 4 weeks. The survey conducted an online survey of 220 students in grades 3-4 who were enrolled in 6 nursing departments located in P metropolitan city and G province, and have clinical practice experience. The collected data were analyzed using SPSS Win 20.0 program. Results: Career preparation behavior had a significant positive correlation with nursing professional intuition(r=.455, p<.001) and self-leadership(r=.539, p<.001), and major satisfaction(r=-.337, p<.001) and clinical practice satisfaction(r=-.380, p<.001) had a significant negative correlation. Self-leadership(β=.424, p<.001) was the most significant factor influencing the study subjects' career preparation behavior, nursing professional intuition(β=.170, p=.010), clinical practice Satisfaction(β=.127, p=.047), employment information(β=.122, p=.023), major satisfaction(β=.137, p=.042) in the order, these variables were found in the order of The explanatory power of the factors affecting the subject's career preparation behavior was 40.2%. Conclusion: Therefore, in order to help nursing students' career preparation behavior, a strategy to provide a variety of employment information and a strategy for nursing intervention that can improve self-leadership, clinical practice satisfaction, and major satisfaction is required.

• Journal of Microbiology and Biotechnology
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• v.31 no.1
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• pp.163-170
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• 2021

Enzyme replacement therapy for lysosomal storage diseases usually requires recombinant enzymes containing mannose-6-phosphate (M6P) glycans for cellular uptake and lysosomal targeting. For the first time, a strategy is established here for the in vitro mannosyl-phosphorylation of high-mannose type N-glycans that utilizes a recombinant Mnn14 protein derived from Saccharomyces cerevisiae. Among a series of N-terminal- or C-terminal-deleted recombinant Mnn14 proteins expressed in Pichia pastoris, rMnn1477-935 with deletion of N-terminal 76 amino acids spanning the transmembrane domain (46 amino acids) and part of the stem region (30 amino acids), showed the highest level of mannosyl-phosphorylation activity. The optimum reaction conditions for rMnn1477-935 were determined through enzyme assays with a high-mannose type N-glycan (Man8GlcNAc2) as a substrate. In addition, rMnn1477-935 was shown to mannosyl-phosphorylate high-mannose type N-glycans (Man7-9GlcNAc2) on recombinant human lysosomal alpha-glucosidase (rhGAA) with remarkably high efficiency. Moreover, the majority of the resulting mannosyl-phosphorylated glycans were bis-form which can be converted to bis-phosphorylated M6P glycans having a superior lysosomal targeting capability. An in vitro N-glycan mannosyl-phosphorylation reaction using rMnn1477-935 will provide a flexible and straightforward method to increase the M6P glycan content for the generation of "Biobetter" therapeutic enzymes.

• The Journal of Bigdata
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• v.5 no.2
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• pp.155-170
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• 2020

The purpose of this study was to apply machine learning techniques (Decision Tree, Random Forest, XGBoost) to data from the 4th~6th year of the Seoul Education Longitudinal Study to find the factors predicting the career maturity of middle school students in Seoul city. In order to evaluate the machine learning application result, the performance of the model according to the indicators was checked. In addition, the model was analyzed using the XGBoostExplainer package, and R and R Studio tools were used for this study. As a result, there was a slight difference in the ranking of variable importance by each model, but the rankings were high in 'Achievement goal awareness', 'Creativity', 'Self-concept', 'Relationship with parents and children', and 'Resilience'. In addition, using the XGBoostExplainer package, it was found that the factors that protect and deteriorate career maturity by panel and 'Achievement goal awareness' is the top priority factor for predicting career maturity. Based on the results of this study, it was suggested that a comparative study of machine learning and variable selection methods and a comparative study of each cohort of the Seoul Education Termination Study should be conducted.

• Korean journal of applied entomology
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• v.25 no.1 s.66
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• pp.53-61
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• 1986

The races of soybean cyst nematode, Heterodera glycines were investigated at 13 localities in Kyungpook, Chungpook and Cheonnam provinces for the resistant soybean variety selection to soybean cyst nematode. Race C, 1, and 5 were distributed and among them race 5 was dominant in Korea. Native soybean 203 lines and 25 introduced soybean varieties were investigated in field where soybean cyst nematode race 5 infested. As the result, the reproduction of soybean cyst nematode in native soybean lines decreased on entry number 18, 21, 36, 38, 41, 42, 43, 45, 55, 59, 68, 72, 75, 93, 94, 95, 98, 123, 131, 136, 146, 170, 174, 187, 190, 191 than others. And then, in pot experiment, entry number 170 showed moderately resistant with 10 cysts per root, while entry number 55 was decreased reproduction a little and the other 25 line appeared susceptibility. In introduced soybean varieties, Peking, Illsoy and PI90763 showed resistance and not reproduction in field and pot experiment. But Custer, Delmar, Dyer and Jackson represented moderately resistant under 10 cysts, while the other 18 varieties were susceptible. In yield analysis, native soybean line 170 showed the same tendency as Peking and PI90763 known for resistant varieties in decreased rate of branch number, pod number, pod weight per plant and weight of 100 grains. Peking and PI90763 decreased at the rate of under 1.6% in branch number, pod number, pod weight per plant and weight of 100 grains, while Illsoy showed a little higher decreased rate of 3.8% in pod number and 3.4% in pod weight per plant. Custer, Delmar, Dyer and Jackson represented a little higher decreased rate in yield.

• Journal of radiological science and technology
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• v.32 no.3
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• pp.285-291
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• 2009

The aim of the present study was undertaken to investigate the association between diagnostic indices of metabolic syndrome(MetS) with carotid intima-media thickness using ultrasonography. The participants in the study were 315 male employees without carotid atherosclerosis and other cardiovascular disease. This study was approved by the Institutional Review Board of Occupational Safety and Health Research Institute. Written informed consent for the participants in this study was obtained from all individuals. Anthropometric parameters and biochemical characteristics were done using each specific equipments and the NCEP-ATP III criteria were used to define MetS. They were examined by B-mode ultrasound to measure the carotid intima-media thickness(carotid IMT) at the near and far walls of common carotid and bifurcation(bulb). The mean carotid IMT was $0.739{\pm}0.137\;mm$ and it's thickness significantly increased with the increase in age. Also, amounts of systolic and diastolic blood pressure, triglyceride and fasting glucose were significantly increased with the increase in age. Carotid IMT were significantly correlated with BMI(r=0.170, p=0.004), systolic(r=0.148, p=0.011) and diastolic blood pressure(r=0.123, p=0.036) and HDL-cholesterol(r=-0.164, p=0.005). On multiple logistic regression analysis for the diagnostic indices of MetS, carotid IMT were significantly associated with blood pressure(OR=4.220, p<0.01) and MetS(OR=1.301, p<0.05). The results indicate that blood pressure and MetS are important risk factors for carotid atherosclerosis.

• The Korean Journal of Nuclear Medicine
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• v.31 no.1
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• pp.19-29
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• 1997

Recently, [I-123]IPT SPECT has been used for early diagnosis of Parkinson's patients(PP) by imaging dopamine transporters. The dynamic time activity curves in basal ganglia(BG) and occipital cortex(OCC) without blood samples were obtained for 2 hours. These data were then used to measure dopamine transporters by operationally defined ratio methods of (BG-OCC)/OCC at 2 hrs, binding potential $R_v=k_3/k_4$ using graphic method or $R_A$= (ABBG-ABOCC)/ABOCC for 2 hrs, where ABBG represents accumulated binding activity in basal ganglia(${\int}^{120min}_0$ BG(t)dt) and ABOCC represents accumulated binding activity in occipital cortex(${\int}^{120min}_0$ OCC(t)dt). The purpose of this study was to examine the IPT pharmacokinetics and investigate the usefulness of simplified methods of (BG-OCC)/OCC, $R_A$, and $R_v$ which are often assumed that these values reflect the true values of $k_3/k_4$. The rate constants $K_1,\;k_2\;k_3$ and $k_4$ to be used for simulations were derived using [I-123]IPT SPECT and aterialized blood data with a standard three compartmental model. The sensitivities and time activity curves in BG and OCC were computed by changing $K_l$ and $k_3$(only BG) for every 5min over 2 hours. The values (BG-OCC)/OCC, $R_A$, and $R_v$ were then computed from the time activity curves and the linear regression analysis was used to measure the accuracies of these methods. The late constants $K_l,\;k_2\;k_3\;k_4$ at BG and OCC were $1.26{\pm}5.41%,\;0.044{\pm}19.58%,\;0.031{\pm}24.36%,\;0.008{\pm}22.78%$ and $1.36{\pm}4.76%,\;0.170{\pm}6.89%,\;0.007{\pm}23.89%,\;0.007{\pm}45.09%$, respectively. The Sensitivities for ((${\Delta}S/S$)/(${\Delta}k_3/k_3$)) and ((${\Delta}S/S$)/(${\Delta}K_l/K_l$)) at 30min and 120min were measured as (0.19, 0.50) and (0.61, 0,23), respectively. The correlation coefficients and slopes of ((BG-OCC)/OCC, $R_A$, and $R_v$) with $k_3/k_4$ were (0.98, 1.00, 0.99) and (1.76, 0.47, 1.25), respectively. These simulation results indicate that a late [I-123]IPT SPECT image may represent the distribution of the dopamine transporters. Good correlations were shown between (3G-OCC)/OCC, $R_A$ or $R_v$ and true $k_3/k_4$, although the slopes between them were not unity. Pharmacokinetic computer simulations may be a very useful technique in studying dopamine transporter systems.

• Parasites, Hosts and Diseases
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• v.30 no.4
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• pp.323-328
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• 1992

Analysis of siR isolates of Trichemenes veginalis was carried out with sodium dodecyl sulfate- polyacrylamide gel electrophoresis (SDS-PAGE) and enzyme-linked immunoelectrotransfer blot (EITB). Trichloroacetic acid-treated antigens of the 6 isolates revealed 25 protein profiles ranging 12~170 kDa of molecular weight in SDS-PAGE. In EITB, the specific immunogenic bands were visualized at 51 kDa and 96 kDa when HY-1 antigen was probed with difFerent mice sera immunized with 6 isolates of T. vaginalis. The banding patterns with different sera showed isolate-to-isolate variability. In EITB, homologous antigen (HY-1) did not show any enhanced response in reacting to homologous antiserum(HY-1) when 6 isolates of T. vaginalis were probed with a single serum (HY-1). It is assumed that the different banding patterns of six isolates show isolate-to-isolate variability and immunogenic common bands in 41, 47, 74 and 9:k kDa on EITB may connote the important significance on immune response in T. vaginalis infection.

• Journal of Microbiology and Biotechnology
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• v.30 no.7
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• pp.1072-1081
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• 2020

Screening suitable strains with high temperature adaptability is of great importance for reducing the cost of temperature control in microalgae cultivation, especially in summer. To obtain high temperature-tolerant diatoms, water samples were collected in summer from 7 different regions of China across the Northeast, North and East. A total of 731 water samples was collected and from them 131 diatom strains were isolated and identified based on the 18S rRNA sequences. Forty-nine strains out of the 131 diatoms could survive at 30℃, and 6 strains with relatively high biomass and lipid content at high temperature were selected and were found to be able to grow at 35℃. Cyclotella sp. HB162 had the highest dry biomass of 0.46 g/l and relatively high triacylglycerol (TAG) content of 237.4 mg/g dry biomass. The highest TAG content of 246.4 mg/g dry biomass was obtained in Fistulifera sp. HB236, while Nitzschia palea HB170 had high dry biomass (0.33 g/l) but relatively low TAG content (105.9 mg/g dry biomass). N. palea HB170 and Fistulifera sp. HB236 presented relatively stable growth rates and lipid yields under fluctuating temperatures ranging from 28 to 35℃, while Cyclotella HB162 maintained high lipid yield at temperatures below 25℃. The percentage of saturated fatty acids and monounsaturated fatty acids in all the 6 strains was 84-91% in total lipids and 90-94% in TAGs, which makes them the ideal feedstock for biodiesel.