• Title/Summary/Keyword: R-index

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Studies on the Correlation between SPF index and Primary Irritation Index of Octylmethoxycinnamte (Octylmethoxycinnamate의 SPF 지수와 피부자극지수와의 상관성 연구)

  • 서수경;김종원;최주영;서경원;박창원;김규봉;김광진;이선희
    • Environmental Mutagens and Carcinogens
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    • v.22 no.4
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    • pp.296-302
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    • 2002
  • In recent years, the safety of sunscreens have been challenged based on the reports of its adverse effects on users; dermatitis, allergic contact dermatitis, photoallergic contact dermatitis. In the toxicological aspect, the need to investigate the safety of sunscreens is steadily increasing. However, there were few studies on the correlation between sun protection factor (SPF) and the safety of sunscreens. The objective of this study was to assess whether there was a correlation between SPF and the skin irritation index of sunscreens. Octyl methoxycinnamate (OMC) was selected, which was the most frequently used (about 92% in korea and about 90% in the world) in sunscreens. In vitro SPF test was performed using the standard samples recommended by KFDA guideline. We examined primary and cumulative skin irritation and eye irritation of OMC standard sample as well as homosalate. As in vitro SPF was increased, skin irritation index was increased in primary skin irritation test ($r^2$=0.986) and cumulative skin irritation test ($r^2$=0.939). In addition, OMC was non-irritating and non-sensitizing. In this results, there was a good correlation between SPF index and skin irritation index.

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Occurrence of a Natural Interspecific Hybrid between Rhodeus pseudosericeus and R. notatus in Sangcheon Stream of the Han River, Korea (한강수계 상천천에서 한강납줄개 Rhodeus pseudosericeus와 떡납줄갱이 R. notatus의 종간 자연잡종 출현)

  • Kwak, Yeong-Ho;Kim, Keun-Yong;Kim, Keun-Sik;Song, Ha-Yun
    • Korean Journal of Ecology and Environment
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    • v.53 no.3
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    • pp.275-285
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    • 2020
  • Two specimens presumed to be hybrids of Rhodeus pseudosericeus and R. notatus were collected from the Sangcheon Stream of the Han River, Korea. The body color of natural hybrid individuals was yellowish brown, showing the intermediate characteristics of R. pseudosericeus and R. notatus, but overall, the characteristics of R. notatus were similar. Meristic and morphometric characters, the number of dorsal fin rays, anal fin rays and longitudinal row scales showed a hybrid index (HI) of 0, indicating the characters of R. notatus. The hybrid index of predorsal length (HI=74.6), preanal length (HI=75.3), and preventral length (HI=77.6) were similar to the characters of the R. pseudosericeus. Also four characters were appeared to have intermediate characters between R. pseudosericeus and R. notatus; number of gill rakers (HI=55.3), body depth (HI=67.9), snout length (HI=43.4), and inter orbital width (HI=44.8). The rest of 14 characters deviated between 0 and 100, showing unique characteristics of hybrid individuals. Recombination activating gene 1 (RAG1) analysis, hybrids were identified as natural hybrids due to the overlapping peaks of their parent species. Also, as a result of analysis using the cytochrome b gene (COB), one individual was derived from R. pseudosericeus, while the other was derived from R. notatus.

The Study on Development of R&D Technology Rating Methodology in the Defense Area (국방 R&D기술 등급평가 방법론 개발 연구)

  • Jung, You-Jin;Kim, Joon-Young;Joung, Tae-Yun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.2
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    • pp.158-167
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    • 2017
  • This paper presents the technology rating methodology that is applicable to defense R&D technology. First, a technology profitability index was developed using multiple regression analysis to forecast the revenue from technology transfer. Secondly, the technology evaluation index was derived using hierarchical analysis with expert opinion. Finally, the weighted average of the technology profitability index and technology evaluation index were calculated to derive the technology rating. This study is significant in that it is first attempt to evaluate defense R&D technology by rating. If the defense R&D technology rating methodology is applied in practice, it can contribute to efficient R&D budget allocation. In addition, it will help in the vitalization of technology transfer in the defense R&D sector.

Serum Insulin, Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Protein-3 Levels in Obese Adolescents (비만 청소년에서 Insulin, Insulin-like Growth Factor-I, Insulin-like Growth Factor Binding Protein-3에 대한 연구)

  • Kwon, Jung Hyun;Kim, Hyun Jin;Hong, Young Mi
    • Clinical and Experimental Pediatrics
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    • v.48 no.11
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    • pp.1172-1178
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    • 2005
  • Purpose : Childhood Obesity is increasing throughout the world, and it is known to incur many diseases especially in later life such as diabetes and cardiovascular disorders. The purpose of this study was to investigate the association between obesity and insulin, insulin-like growth factor-I (IGF-I), insulin-like growth factor binding protein-3(IGFBP-3) and know if these factors are useful in predicting cardiovascular diseases. Methods : The study group consisted of 64 moderate and severe obese adolescents and the controls were normal adolescents of the same age. body mass index(BMI) was calculated by height and weight; systolic and diastolic blood pressure was measured at resting state. After 10-hour fasting period, blood cholesterol, triglyceride, high density lipoprotein(HDL) cholesterol, low density lipoprotein(LDL) cholesterol, glucose, insulin, free fatty acid, IGF-I and IGFBP-3 were measured. Results : Insulin was significantly higher in the obese adolescent group than the control group(obese group $15.6{\pm}7.0{\mu}IU/mL$, P<0.01). IGF-I was also significantly higher in the obese adolescent group than the control group(obese group $498.1{\pm}122.2ng/mL$, P<0.05). In addition, IGFBP-3 was significantly higher in the obese adolescent group than the control group(obese group $3,777{\pm}4,721ng/mL$, P<0.05). Insulin showed significantly positive correlation with BMI(r=0.3944) and obesity index(r=0.34). IGFBP-3 were significantly correlated with obesity index(r=0.419), diastolic blood pressure (r=0.264) and BMI(r=0.247). Insulin resistance index significantly positive correlation with BMI(r=0.595), blood triglycerid level(r=0.515) and obesity index(r=0.469). Conclusion : Serum insulin, insulin resistance index, IGF-I and IGFBP-3 levels may be useful to predict cardiovascular diseases in adolescent obesity.

Species Diversity Analysis of the Mushroom in Mt. Chiak (치악산 발생 버섯의 종 다양성 비교 분석)

  • Lee, Byung Kook;Eom, Ki Cheol;Seok, Soon Ja
    • The Korean Journal of Mycology
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    • v.41 no.2
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    • pp.57-66
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    • 2013
  • The mushrooms collected at seven areas of Mt. Chiak in 2002 and 2003 were classified to analyse the distribution and species diversity. Frequency (number of mushroom : N), number of species (S), relative species density (RSD), similarity index (C), richness index (R1), variety index (V1), evenness index (E2), and dominance index(D1) were investigated. Total N and S was 143 and 84, respectively. The RSD was 0.179 ~ 0.226 of the 7 areas. The yearly C of the total area (0.213) was 8.2%. more higher than the average C of 7 areas (0.131). The order in the coefficient of variation (CV) of the indicator for 7 areas was N (10.5%) > D1 (9.2%) > V1 (8.9%) > S (8.5%) > R1 (7.4%) > E2 (2.2%). The average R1 of the 7 areas was 5.36 with the range from 4.85 to 6.01, and 16.72 for the total area. The average V1 of the 7 areas was 16.24 with the range from 14.44 to 18.66, and 68.82 for the total area. The average E2 of the 7 areas was 0.95 with the range from 0.926 to 0.982, and 0.819 for the total area. The average D1 of the 7 areas was 0.071 with the range from 0.055 to 0.073, and 0.081 for the total area. The correlation between N and 5 kinds of diversity indicator (S, R1, V1, E2, D) was not statistically significant, but the correlation between R1, E2 and D1 was statistically significant each other.

Tmr-Tree : An Efficient Spatial Index Technique in Main Memory Databases (Tmr-트리 : 주기억 데이터베이스에서 효율적인 공간 색인 기법)

  • Yun Suk-Woo;Kim Kyung-Chang
    • The KIPS Transactions:PartD
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    • v.12D no.4 s.100
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    • pp.543-552
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    • 2005
  • As random access memory chip gets cheaper, it becomes affordable to realize main memory-based database systems. The disk-based spatial indexing techniques, however, cannot direct apply to main memory databases, because the main purpose of disk-based techniques is to reduce the number of disk accesses. In main memory-based indexing techniques, the node access time is much faster than that in disk-based indexing techniques, because all index nodes reside in a main memory. Unlike disk-based index techniques, main memory-based spatial indexing techniques must reduce key comparing time as well as node access time. In this paper, we propose an efficient spatial index structure for main memory-based databases, called Tmr-tree. Tmr-tree integrates the characteristics of R-tree and T-tree. Therefore, Nodes of Tmr-tree consist of several entries for data objects, main memory pointers to left and right child, and three additional fields. First is a MBR of a self node, which tightly encloses all data MBRs (Minimum Bounding Rectangles) in a current node, and second and third are MBRs of left and right sub-tree, respectively. Because Tmr-tree needs not to visit all leaf nodes, in terms of search time, proposed Tmr-tree outperforms R-tree in our experiments. As node size is increased, search time is drastically decreased followed by a gradual increase. However, in terms of insertion time, the performance of Tmr-tree was slightly lower than R-tree.

Prediction of concrete strength from rock properties at the preliminary design stage

  • Karaman, Kadir;Bakhytzhan, Aknur
    • Geomechanics and Engineering
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    • v.23 no.2
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    • pp.115-125
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    • 2020
  • This study aims to explore practical and useful equations for rapid evaluation of uniaxial compressive strength of concrete (UCS-C) during the preliminary design stage of aggregate selection. For this purpose, aggregates which were produced from eight different intact rocks were used in the production of concretes. Laboratory experiments involved the tests for uniaxial compressive strength (UCS-R), point load index (PLI-R), P wave velocity (UPV-R), apparent porosity (n-R), unit weight (UW-R) and aggregate impact value (AIV-R) of the rock samples. UCS-C, point load index (PLI-C) and P wave velocity (UPV-C) of concrete samples were also determined. Relationships between UCS-R-rock parameters and UCS-C-concrete parameters were developed by regression analyses. In the simple regression analyses, PLI-C, UPV-C, UCS-R, PLI-R, and UPV-R were found to be statistically significant independent variables to estimate the UCS-C. However, higher coefficients of determination (R2=0.97-1.0) were obtained by multiple regression analyses. The results of simple regression analysis were also compared to the limited number of previous studies. The strength conversion factor (k) values were found to be 14.3 and 14.7 for concrete and rock samples, respectively. It is concluded that the UCS-C can roughly be estimated from derived equations only for the specified rock types.

Comparison of semiparametric methods to estimate VaR and ES (조건부 Value-at-Risk와 Expected Shortfall 추정을 위한 준모수적 방법들의 비교 연구)

  • Kim, Minjo;Lee, Sangyeol
    • The Korean Journal of Applied Statistics
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    • v.29 no.1
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    • pp.171-180
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    • 2016
  • Basel committee suggests using Value-at-Risk (VaR) and expected shortfall (ES) as a measurement for market risk. Various estimation methods of VaR and ES have been studied in the literature. This paper compares semi-parametric methods, such as conditional autoregressive value at risk (CAViaR) and conditional autoregressive expectile (CARE) methods, and a Gaussian quasi-maximum likelihood estimator (QMLE)-based method through back-testing methods. We use unconditional coverage (UC) and conditional coverage (CC) tests for VaR, and a bootstrap test for ES to check the adequacy. A real data analysis is conducted for S&P 500 index and Hyundai Motor Co. stock price index data sets.

Analytical Studies on The Useful Characters Affecting The Lodging Resistance of Wheat and Barley Varieties (맥류의 도복에 관여하는 유용형질의 분석에 관한 연구)

  • Chang-Hwan Cho
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.11
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    • pp.105-117
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    • 1972
  • This experiment has been made to study the relationship between several characters affecting the field lodging and to establish some useful standards for selection of lodging resistant varieties and to classify the degree of lodging resistance in wheat and barley varieties of different sources. The experiment was carried at the Crop Experiment Station, Suwon in 1968. The results obtained are summarized as followings. a. The lodging index modified with bending moment of culm at breaking seemed to be the most useful character in checking the lodging resistance. Highly significant positive correlation (Barley; r=0.40-0.67, Wheat; r=0.46-0.68) was obtained between the lodging index and actual field lodging. b. Between two essential components expressing bending stiffness of the culm, the bending moment at breaking and secondary moment of inertia, a highly significant positive correlation (Barley; r=0.59, wheat; r=0.46-0.53) was observed. c. The bending stiffness of culm got stronger as the dry weight per unit culm, which express the quantity of accumulated dry matters in culm, increased. The correlation coefficient between those two factors was 0.35 to 0.40 in barley and 0.33 to 0.76 in wheat respectively. d. In both wheat and barley, highly significant negative correlation between lodging index and the other factors such as dry weight per unit culm (Barley; r=-0. 51 to -0.70, Wheat; r=-0.65 to -0.83) and bending moment of culm at breaking (Barley; r=-0.29 to -0.69, Wheat: r=-0.54 to -0.89) were observed. Particulary, weight of culm at breaking, secondary moment of inertia and section modulus showed significant negative correlation with lodging index in wheat. e. Outside diameter of culm expressed more intimate relationship with physical characteristics of culm than inside diameter and also showed highly significant correlation with weight of culm at breaking (Barley; r=0.42-0.56, Wheat; r=0.39-0.44) and with bending moment of culm at breaking (Barley; r=0.40-0.41, Wheat; r=0.38-0.49) and with secondary moment of inertia (Barley; r=0.56-0.57, Wheat; r=0.28-0.98) and with section modulus (Wheat; r=0.22-0.96). Between the thickness of culm and physical characteristics of culm also showed the positive correlation. f. There was positive correlation between the culm length and actual field lodging in several groups of variety among the varieties tested. But the culm length seemed to undesirable as a selection measure for the selection of the lodging resistant variety considering the stiffness of culm. g. In classification of lodging resistance for the varieties tested, many Korean barley varieties expressed excellent lodging resistant than wheat, but most of the wheat and barley varieties from Japan considered quite resistant to lodging. h. In selection of lodging resistant varieties, lodging index lower than 1.67 in barley and 1. 76 in wheat considered highly resistant to actual field lodging.

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Analysis of Relation between Streamflow Variability and Baseflow Index (하천유량 변동성과 기저유출비의 관계분석)

  • Han, Jeong-Ho;Geum, Dong-Hyeok;Sin, Yong-Cheol;Im, Gyeong-Jae;Jeong, Yeong-Hun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2015.05a
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    • pp.146-146
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    • 2015
  • 하천관리는 직접유출과 기저유출로 구성된 하천유량의 특성을 이해하는 것으로부터 시작된다. 따라서 직접유출과 기저유출의 특성은 직접적으로 하천유량의 변동성으로 전달된다. 이러한 점을 고려했을 때 전략적인 하천관리를 위해서는 직접유출/기저유출과 하천유량의 관계를 분석하는 것이 필요하다. 이를 대해 본 연구의 목적은 하천유량의 변동성과 기저유출비(Baseflow Index, BFI)의 관계를 분석하고, 이러한 관계를 일관성 있게 나타낼 수 있는 하천유량 변동성 지표(Streamflow Variability Index, SVI)를 제시하는 것이다. 본 목적을 달성하기 위해 국내 총 91개 유량관측소를 대상으로 유황계수, R-B Index(Richards-Baker Flashiness Index), 변동계수(Coefficient of Variation), Q5:Q95 ratio 등의 SVI를 적용하였다. 이와 더불어, BFI를 산정하기 위하여 기저유출 분리 모형인 WHAT, PART, HYSEP, BFLOW를 사용하였다. 연구결과는 BFI값이 증가 할수록 SVI의 값은 감소하는 경향을 나타냈다. 다양한 SVI 가운데 BFI에 대한 R-B Index의 평균 결정계수가 0.66로 가장 큰 값을 나타냈으며, 특히 WHAT 모델의 Local Minimum Method(LMM)과의 결정계수가 0.82로 가장 밀접한 관계를 나타냈다. 변동계수 또한 평균 결정계수 값이 0.60으로 높은 값을 보였다. 그 외 유황계수와 Q5:Q95의 평균 결정계수는 각각 0.04와 0.07로 매우 낮은 값을 보였다. 결론적으로 다양한 SVI 가운데 R-B Index가 여러 기저유출 방법으로 산정된 BFI 값들에 대하여 가장 일관성 있는 결과를 보였다. 본 연구의 결과는 하천의 생태적 기능 유지와 치수안정성을 확보를 고려한 하천관리에 기여할 것이다.

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