• Title/Summary/Keyword: R-Mode

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Palaeoenvironmental Implication of the Quaternary Gravel Sequences on the Basis of Gravel Shape (역의 형태에 의한 제4기 역층준의 고환경적 고찰)

  • Ju Yong Kim;Duck Keun Choi
    • The Korean Journal of Quaternary Research
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    • v.4 no.1
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    • pp.41-57
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    • 1990
  • Gravel shapes of the terrace gravel sequences are compared with the present river gravels and beach gravels in the Pohang and its surrounding areas. Seventeen gravel textural parameters are divided into 5 groups based on R-mode factor analysis. Among them, three parameters (RDm, MPSm, SZstd) are selected for a test of discriminant possibility of palaeoenvironment of the terrace gravel deposits. Marine gravels are in the range of 0.49 to 0.75 in mean roundness, 0.46 to 0.78 in mean maximum projection sphericity and 0.39 to 1.85 in standard deviation of size, whereas river gravels are 0.28 to 0.51 in mean roundness, 0.66 to 0.72 in mean maximum projection sphericity and 1.04 to 1.81 in standard deviation of size. For practical access to the palaeoenvironment discrimination, a bivariant diagram between mean roundness and mean maximum projection sphericity is the most effective. The marine terrace gravels are plotted within the variation range of present beach gravels and show 0.49 to 0.71 in mean roundness and 0.59 to 0.66 in mean maximum projection sphericity. The gravels of river terrace vary within the range of gravels derived from present river bed and are characterized as 0.36 to 0.48 in mean roundness and 0.66 to 0.71 in mean maximum projection sphericity.

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Evaluation of Groundwater Quality Using Factor Aanlyses and Agrochemicals in an Agricultural Area (요인분석과 농약성분 특성에 의한 농업지역의 지하수 수질 평가)

  • Lee, Jeong-Hwan;Hamm, Se-Yeong;Kim, Kwang-Sung;Cheong, Jae-Yeol;Ryu, Sang-Min;Kim, Deuk-Ho;Kim, Hyun-Ji
    • Economic and Environmental Geology
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    • v.42 no.3
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    • pp.217-234
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    • 2009
  • This study characterized groundwater quality and the influence of agrochemicals in a part of Ilgwang-Myeon agricultural area in Gijang-Gun, Busan Metropolitan City, using factor analyses. From the 1st, 2nd, and 3rd analyses of groundwater samples, the mean concentrations of $Ca^{2+}$, $Na^+$, $Mg^{2+}$, $K^+$, $Zn^{2+}$, $Cu^{2+}$, $Fe^{2+}$, $Al^{3+}$, $NO_3\;^-$, $Cl^-$, $SO_4\;^{2-}$, $F^-$, and $SiO_2$ were higher in the 2nd analysis than the other analyses. Pesticide carbofuran and herbicide alachlor were detected at the wells more than a half of all the wells in the 2nd analysis but not in the 4th analysis. This fact may be explained by that a higher precipitation induced higher infiltration rate of contaminants into groundwater during the 2nd survey. According to R- and Q-mode factor analyses, and chemical composition, inorganic constituents excepting $SiO_2$, $HC0_3\;^-$-, and $F^-$ may be influenced by anthropogenic sources (manures, synthetic fertilizers, and domestic wastes), seawater as well as water-mineral interaction. A typical indicator of groundwater contamination, nitrate, exceeds around 4-5 times over the Korean standard for drinking water. Additionally, the influence of seawater diminishes from the seaside to inland.

cAMP induction by ouabain promotes endothelin-1 secretion via MAPK/ERK signaling in beating rabbit atria

  • Peng, Li-qun;Li, Ping;Zhang, Qiu-li;Hong, Lan;Liu, Li-ping;Cui, Xun;Cui, Bai-ri
    • The Korean Journal of Physiology and Pharmacology
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    • v.20 no.1
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    • pp.9-14
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    • 2016
  • Adenosine 3',5'-cyclic monophosphate (cAMP) participates in the regulation of numerous cellular functions, including the $Na^+-K^+$-ATPase (sodium pump). Ouabain, used in the treatment of several heart diseases, is known to increase cAMP levels but its effects on the atrium are not understood. The aim of the present study was to examine the effect of ouabain on the regulation of atrial cAMP production and its roles in atrial endothelin-1 (ET-1) secretion in isolated perfused beating rabbit atria. Our results showed that ouabain ($3.0{\mu}mol/L$) significantly increased atrial dynamics and cAMP levels during recovery period. The ouabain-increased atrial dynamics was blocked by KB-R7943 ($3.0{\mu}mol/L$), an inhibitor for reverse mode of $Na^+-Ca^{2+}$ exchangers (NCX), but did not by L-type $Ca^{2+}$ channel blocker nifedipine ($1.0{\mu}mol/L$) or protein kinase A (PKA) selective inhibitor H-89 ($3.0{\mu}mol/L$). Ouabain also enhanced atrial intracellular cAMP production in response to forskolin and theophyline ($100.0{\mu}mol/L$), an inhibitor of phosphodiesterase, potentiated the ouabain-induced increase in cAMP. Ouabain and 8-Bromo-cAMP ($0.5{\mu}mol/L$) markedly increased atrial ET-1 secretion, which was blocked by H-89 and by PD98059 ($30{\mu}mol/L$), an inhibitor of extracellular-signal-regulated kinase (ERK) without changing ouabain-induced atrial dynamics. Our results demonstrated that ouabain increases atrial cAMP levels and promotes atrial ET-1 secretion via the mitogen-activated protein kinase (MAPK)/ERK signaling pathway. These findings may explain the development of cardiac hypertrophy in response to digitalis-like compounds.

Structures and Variability of the T-S field and the Current across the Korea Strait (대한해협 횡단면 상의 수온-염분과 해류의 구조 및 변동)

  • RO, YOUNG JAE;PARK, MOON-JIN;LEE, SANG-RYONG;LEE, JAE CHUL
    • 한국해양학회지
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    • v.30 no.4
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    • pp.237-249
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    • 1995
  • To understand the cross-sectional structures of temperature, salinity and current across the Korea Strait, field measurements were carried out for the period of May 2 to 20, 1994. Using the R/V Tam Yang, detailed CTD profiles and ADCP records were obtained and used to examine the mean and variability field on two time scales (15 days and 25 hours). A sharp coastal front in the middle of the Korea Strait exists across which two different water masses, i.e., warm and saline water in the eastern side and cold and less saline water in the western side are neighboring. We observed highly variable field of T and S apparently caused by the westward movement of warm and saline water mass. Short-term fluctuations of T and S in the middle layer are remarkable and their importance was analysed as the first Eigen mode accounting for more than 50% of total variances. The currents in th Korea Strait are strongly influenced by tidal currents with spring and neap variation whose maximum speed ranges 80-90 and 60-70 cm/s respectively near the central portion of the channel. Strong southward tidal current could even mask the Tsushima Current completely. Results of harmonic analysis show that the magnitudes of semidiurnal, diurnal and mean components of currents are comparable to each other at spring and neap tide conditions. The volume transport across the western channel of the Korea Strait were estimated to be 2.1 Sv at neap tide condition and 3.4 Sv at spring tide condition.

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Applicability of ABC-ELISA and Protein A-ELISA in serological diagnosis of cysticercosis (유구낭미충증의 혈청학적 진단을 위한 ABC-ELISA와 Protein A-ELISA의 유용성)

  • Lee, Jong-Hyun;Kong, Yoon;Ryu, Jae-Young;Cho, Seung-Yull
    • Parasites, Hosts and Diseases
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    • v.31 no.1
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    • pp.49-56
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    • 1993
  • Specific antibody test in serum and cerebrosinal fluid (CSF) is still the main mode of serological diagnosis of cystiercosis. Of different techniques of artibody test, enzyme-linked immunosorbent assay (micro-ELISA) has widely been applied. This study was undertaken to observe whether diagnostic capability can be Improved by applying more sensitive techniques such as Protein A-ELISA and avidin biotin complex ELISA (ABC-ELISA). When evaluated using 115 sera of human cysticercosis, the antibody positive rates were not significantly improved in Protein A-ELISA (82.6%) and in ABC-ELISA (86.1%) than in micro-ELISA (81.7%). The specificities, evaluated in 165 sera from other diseases and normal controls, were significantly improved (88.5% by micro-ELISA, 93.3% by Protein A-ELISA and 93.8% by ABC-ELISA). Antibody levels (absorbance, abs.) in individual serum were correlated well (r : 0.83∼0.86) each other. An actual benefit of Protein A-ELISA and ABC-ELISA was that they needed smaller amount of test sample.

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Research of Hydraulic Breaker with Rock Properties Predictability Using the ICT (ICT 융합기술을 활용한 암반특성 예측기능을 가진 유압 브레이커 개발에 관한 연구)

  • Yoon, Bok Joong;Lee, Kil Soo;Lim, Hoon;Lee, Ho Yeon;Lee, Myung Gyu;Kwon, Hyuk Jin;Kim, Kab Tae;Joo, Jin Moo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.41 no.7
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    • pp.683-689
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    • 2017
  • We have carried out the development for hydraulic breaker which can be operated by optimal mode with ICT convergence technology. This developed system can predict the rock properties. Moreover, this system can maximize the energy efficient with intelligent control of hydraulic system. In order to provide the optimal impact force, this system can measure the descending depth of piston with the proximity sensor and discriminate the rock properties with the measuring data and control the piston stroke using solenoid valve eventually. In addition, we have developed the controller, display module and operating device for cascade (multi-level impact) system and applied the module which can communicate each system by wireless communications. In conclusion, the control system which can control the multi-level impact in accordance with strength of rocks has been developed and approved by several field tests.

Mode of Action of Streptomycin Resistance in the Citrus Canker Pathogen (Xanthomonas smithii subsp. citri) in Jeju Island

  • Hyun, Jae-Wook;Kim, Hyo-Jung;Yi, Pyoung-Ho;Hwang, Rok-Yeon;Park, Eun-Woo
    • The Plant Pathology Journal
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    • v.28 no.2
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    • pp.207-211
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    • 2012
  • It has been known that streptomycin resistance in bacteria can occur as a results of chromosomal mutation or through gene acquisition or both. Chromosomal mutations for resistances are point mutations in the rpsL gene, which alter ribosomal protein S12. Acquired resistance has occurred when an $Sm^R$ plasmid carrying transposon Tn5393 with tandem strA-strB gene is transferred by conjugation. A total of 686 isolates of Xanthomonas smithii subsp. citri causal agent of citrus canker disease were collected from 26 citrus orchards in Jeju Island in 2003 and 2004 seasons. Forty-nine of 111 isolates from streptomycin non-sprayed orchards in 2003 season were resistant to streptomycin. Of 107 isolates from orchards sprayed one time with streptomycin, 58 isolates were resistant, and 166 of 221 isolates from orchards sprayed two times with streptomycin were resistant. In 12 orchards sprayed three or more times with streptomycin, 219 of 247 isolates were resistant to streptomycin. Twenty-five isolates of X. smithii subsp. citri were surveyed to identify the mechanisms of streptomycin resistance in this study. Twenty-one of these 25 isolates were resistant to streptomycin, and it was proven by PCR assay that 18 of the 21 streptomycin resistant isolates have the strB gene. In sixteen of the 21 streptomycin resistant isolates, it was occurred a point mutation altered codon lysine (AAG)-41 of rpsL gene to arginine (AGG). The streptomycin-sensitive isolates easily acquired the resistance by mixed culture with resistant isolates. The strB gene was amplified from the isolates that acquired the resistance by mixed culture, and one isolate of them was also point-mutated in codon 41 of rpsL gene to be resistant. In this study, most of the streptomycin-resistant isolates of X. smithii sub sp. citri in Jeju island expressed the resistance by both chromosomal point mutation and gene acquisition, and the resistance was easily acquired through conjugation by culture mixed with streptomycin resistant and sensitive strains.

A Geochemical Study on Pyrophyllite Deposits and Andesitic Wall-Rocks in the Milyang Area, Kyeongnam Province (경남 밀양지역 납석광상과 안산암질 모암의 지구화학적 연구)

  • Oh, Dae-Gyun;Chon, Hyo-Taek;Min, Kyoung-Won
    • Economic and Environmental Geology
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    • v.25 no.1
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    • pp.27-39
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    • 1992
  • Several pyrophyllite deposits occur around the Milyang area where Cretaceous andesitic rocks and spatially related granitic rocks are widely distributed. Pyrophyllite ores consist mainly of pyrophyllite, and quartz with small amount of sericite, pyrite, dumortierite, and diaspore. The andesitic rocks and spatially related granitic rocks in this area suggest that they could be formed from the same series of a calc-alkaline magma series. The contents of $SiO_2$, $Al_2O_3$, LOI(loss on ignition) are enriched, and $K_2O$, $Na_2O$, CaO, MgO, $Fe_2O_3$ are depleted in altered andesitic rocks and ores. Enrichment of As, Cr, Sr, V, Sb and depletion of Ba, Cs, Ni, Rb, U, Y, Co, Sc, Zn are characteristic during mineralization. The pyrophyllite ores can be discriminated from the altered-and unaltered wall-rocks by an increasing of $(La/Lu)_{cn}$ from 4.18~22.13 to 8.98~55.05. In R-mode cluster analysis, Yb-Lu-Y, La-Ce-Hf-Th-U-Zr, $TiO_2-V-Al_2O_3$, Sm-Eu, $CaO-Na_2O-MnO$, Cu-Zn-Ag, $K_2O-Rb$ are closely correlated. In the discriminant analysis of multi-element data, $P_2O_5$, As, Cr and $Fe_2O_3$, Sr are helpful to identify the ores from the unaltered-and altered wall-rocks. In the factor analysis, the factors of alteration of andesitic rocks and ore mineralization were extracted. In the change of ions per unit volume, $SiO_2$, $Al^{3+}$ and LOI are enriched and $Na^+$, $K^+$, $Ca^{2+}$, $Mg^{2+}$, $Mn^{2+}$ and $Fe^{3+}$ are depleted during the alteration processes. The Milyang and the Sungjin pyrophyllite deposits could be mineralized by hydrothermal alteration in a geochemical condition of low activity ratio of alkaline ions to hydrogen ion with reference to spatially related granitic rocks.

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Assessment of correlation between markers of ambient monitoring and biological monitoring of dimethylformamide for workers in synthetic leather manufacturing factories in Korea (국내 합성피혁제조업 근로자에 대한 디메틸포름아미드의 공기중 농도와 생물학적 노출지표간의 상관성 평가)

  • Hwang, Yang In;Lee, Mi-Young;Chung, Yun Kyung;Kim, Eun A
    • Analytical Science and Technology
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    • v.26 no.5
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    • pp.315-325
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    • 2013
  • The possibility of acute hepatotoxicity caused by dimethylformamide (DMF) requires regular monitoring of the workers who are using DMF to prevent the occupational disease. The authors performed ambient and biological monitoring of workers involved in synthetic leather manufacturing processes using DMF to assess the correlation between the markers of ambient and biological monitoring of DMF. The authors monitored 142 workers occupationally exposed to DMF from 19 workshops in the synthetic leather and ink manufacturing industries located in northern region of Gyeonggi-do. The subjects answered questionnaire on work procedure and use of personal protective equipment to be classified by exposure type. DMF in air samples collected using personal air samplers, diffusive and active sampler, was analysed using gas chromatograph-flame ionization detector (GC-FID) with DB-FFAP column (length 30 m, i.d. 0.25 mm, film thickness 0.25 ${\mu}m$). Urinary N-methylformamide (NMF) was analysed using gas chromatograph-mass selective detector (GC-MSD) at selected ion monitoring (SIM) mode with DB-624 column (length 60 m, i.d. 0.25 mm, film thickness 1.40 ${\mu}m$). Geometric mean (GM) and geometric standard deviation (GSD) of the ambient DMF was $6.85{\pm}3.43$ ppm, and GM and GSD of urinary NMF was $42.3{\pm}2.7$ mg/L. The ratio of subjects with DMF level over 10 ppm was 44%, and those with urinary NMF over 15 mg/L was 87%. NMF in urine adjusted by DMF in air was $4.61{\pm}2.57$ mg/L/ppm and $9.50{\pm}2.41$ mg/L/ppm, respectively, with or without respirator. There was seasonal differences of NMF in urine adjusted by DMF in air, $7.63{\pm}2.74$ mg/L/ppm in summer and $4.53{\pm}2.29$ mg/L/ppm in winter. The urinary NMF concentration which corresponds to 10 ppm of ambient DMF was 52.7 mg/L (r=0.650, n=128). Considering the difference of the route of exposure which resulted from the compliance of wearing personal protective equipment, the estimated contribution of respiratory and dermal exposure route for DMF was 48.5% vs. 51.5%.

Dynamic Response and Control of Airship with Gust (외란이 작용하는 비행선의 동적 반응 및 제어)

  • Woo, G.A.;Park, I.H.;Oh, S.J.;Cho, K.R.
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.30 no.6
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    • pp.69-77
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    • 2002
  • To acquire the dynamic response and design the controller of the airship, the longitudinal motion of the airship with respect to the vertical gust, which is the nonlinear system, was studied. The effects of the apparent mass and moment of the airship delay the dynamic response and the settling time, which are slower than those of conventional airplanes. The current object of the airship is designed to cruise at 500~1000m altitude. At that height, the atmospheric conditions are generally unstable by wind gust. In this paper, it has been studied for the case of vertical gust, since the apparent mass effects are dominant in has been studied for the case of vertical gust, since the apparent mass effects are dominant in that plane. In addition to the study of the dynamic responses of the airship, the controller was designed using the PID-controller. When the gust was applied, airship responses were recovered of equilibrium states. However, it takes too ling time for recovery and the speed of airship is reduced. So, the aim in this paper was to fasten the recovery speed and to get back the cruising velocity. The control parameters were determined from the stability mode analysis, and the control inputs were the thrust and the elevator deflection angle.