• Title/Summary/Keyword: R&D Department

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$\Theta$-DERIVATIONS ON PRIME RINGS

  • Park, Kyoo-Hong;Jung, Yong-Soo
    • Journal of applied mathematics & informatics
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    • v.12 no.1_2
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    • pp.313-321
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    • 2003
  • In this Paper we show the following: Let R be a prime ring (with characteristic different two) and a $\in$ R. Let Θ, $\phi$ : R longrightarrow R be automorphisms and let d : R longrightarrow R be a nonzero Θ-derivation. (i) if[d($\chi$), a]Θo$\phi$ = 0 (or d([$\chi$, a]$\phi$ = 0) for all $\chi$ $\in$ R, then a+$\phi$(a) $\in$ Z, the conte. of R, (ii) if〈d($\chi$), a〉 = 0 for all $\chi$$\in$R, then d(a) =0. (iii) if [ad($\chi$), $\chi$$\phi$= 0 for all $\chi$$\in$R, then either a = 0 or R is commutative.

Current Status of Stem Cell Treatment for Type I Diabetes Mellitus

  • Kakkar, Anupama;Sorout, Ashima;Tiwari, Mahak;Shrivastava, Pallavi;Meena, Poonam;Kumar Saraswat, Sumit;Srivastava, Supriya;Datt, Rajan;Pandey, Siddharth
    • Tissue Engineering and Regenerative Medicine
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    • v.15 no.6
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    • pp.699-709
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    • 2018
  • BACKGROUND: Diabetes mellitus is a major health concern in current scenario which has been found to affect people of almost all ages. The disease has huge impact on global health; therefore, alternate methods apart from insulin injection are being explored to cure diabetes. Therefore, this review mainly focuses on the current status and therapeutic potential of stem cells mainly mesenchymal stem cells (MSCs) for Type 1 diabetes mellitus in preclinical animal models as well as humans. METHODS: Current treatment for Type 1 diabetes mellitus mainly includes use of insulin which has its own limitations and also the underlying mechanism of diseases is still not explored. Therefore, alternate methods to cure diabetes are being explored. Stem cells are being investigated as an alternative therapy for treatment of various diseases including diabetes. Few preclinical studies have also been conducted using undifferentiated MSCs as well as in vitro MSCs differentiated into ${\beta}$ islet cells. RESULTS: These stem cell transplant studies have highlighted the benefits of MSCs, which have shown promising results. Few human trials using stem cells have also affirmed the potential of these cells in alleviating the symptoms. CONCLUSION: Stem cell transplantation may prove to be a safe and effective treatment for patients with Type 1 diabetes mellitus.

Posner's First Theorem for *-ideals in Prime Rings with Involution

  • Ashraf, Mohammad;Siddeeque, Mohammad Aslam
    • Kyungpook Mathematical Journal
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    • v.56 no.2
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    • pp.343-347
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    • 2016
  • Posner's first theorem states that if R is a prime ring of characteristic different from two, $d_1$ and $d_2$ are derivations on R such that the iterate $d_1d_2$ is also a derivation of R, then at least one of $d_1$, $d_2$ is zero. In the present paper we extend this result to *-prime rings of characteristic different from two.

Investigation of post-translational modification of the secreted protein expressed in insect cell lines using baculovirus expression vector system(BEVS)

  • Yun, Eun-Young;Goo, Tae-Won;Kim, Sung-Wan;Park, Kwang-Ho;Hwang, Jae-Sam;Kang, Seok-Woo;Kwon, O-Yu
    • Proceedings of the Korean Society of Sericultural Science Conference
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    • 2003.04a
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    • pp.82-83
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    • 2003
  • In previous experiment, we reported when the heterologous protein is expressed by using baculovirus expression vector system (BEVS), although the amount of intracellular protein is abundant, the amount of extracellular Protein is poor. As the link in the chain of the research, we investigated the secretory pathway, important in case of the secretory protein, of the protein expressed in insect cells using BEVS. (omitted)

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Design of Probabilistic Model for Optimum Manpower Planning in R&D Department (연구개발 부문 적정인력 산정을 위한 확률적 모형설계에 관한 연구)

  • Kim, ChongMan;Ahn, JungJin;Kim, ByungSoo
    • Journal of Korean Society for Quality Management
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    • v.41 no.1
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    • pp.149-162
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    • 2013
  • Purpose: The purpose of this study was to design of a probabilistic model for optimum manpower planning in R&D department by Montecarlo simulation. Methods: We investigate the process and the requirement of manpower planning and scheduling in R&D department. The empirical distributions of necessary time and manpower for R&D projects are developed. From the empirical distributions, we can estimate a probability distribution of optimum manpower in R&D department. A simulation method of estimating the probability distribution of optimum manpower is considered. It is a useful tool for obtaining the sum, the variance and other statistics of the distributions. Results: The real industry cases are given and the properties of the model are investigated by Montecarlo Simulation. we apply the model to the research laboratory of the global company, and investigate and compensate the weak points of the model. Conclusion: The proposed model provides various and correct information such as average, variance, percentile, minimum, maximum and so on. A decision maker of a company can easily develop the future plan and the task of researchers may be allocated properly. we expect that the productivity can be improved by this study. The results of this study can be also applied to other areas including shipbuilding, construction, and consulting areas.

A Quality Management Model Contingent to R&D Characteristics (연구개발 특성을 고려한 품질경영 모형)

  • Yoon, JaeWook
    • Journal of Korean Institute of Industrial Engineers
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    • v.43 no.2
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    • pp.90-99
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    • 2017
  • As the importance of R&D has increased, there have been various efforts to apply the quality management principles and tools to R&D activities in order to manage them effectively. The R&D sector differs from other value chains, so it may be difficult to apply quality management without proper considerations of R&D characteristics. This study describes the characteristics of R&D as high uncertainty and risk, diversity of R&D types, project-based activities, importance of strategic goals and business models, and importance of intangible assets. Three well accepted R&D quality management models are reviewed and implications for quality management and R&D characteristics are summarized. Based on these findings, the management targets of R&D quality management are classified into management level (organization, project) and management focus (process, output), and the contexts of R&D quality management are classified into R&D type (research, development) and market/customer requirement clarity (fluid, specific), and appropriate R&D quality management activities in each situations have been suggested.

Economic Analysis Study on the R&D Effect of Performance Improvement of the Tri-generation Fuel Cell System (연료전지 삼중열병합 시스템의 성능개선 R&D 효과에 대한 경제성 분석 연구)

  • Ahn, Jong-Deuk;Lee, Kwan-Young;Seo, Seok-Ho
    • New & Renewable Energy
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    • v.18 no.2
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    • pp.26-39
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    • 2022
  • Considering the recent substantial increase in national research and development (R&D) budgets in the energy sector there has been increased Interest in the effectiveness of government R&D investments. We conducted a case study to calculate the allowable scale and effectiveness of R&D investment by calculating the direct performance improvement effect resulting from R&D investment as an economic value. Using conditions that existed prior to R&D investments as a reference, five cases in which performance improved due to R&D investments were compared and analyzed. The government's financial investment is increasing rapidly in line with the establishment of the national hydrogen roadmap. R&D is needed to enhance the current low technology readiness level of hydrogen fuel cells compared to solar and wind energy fields. Therefore, an R&D project to improve the performance of the fuel cell system was selected as this case study's subject. Using the results in this study, the allowable level of investment in the task unit of national R&D projects could be calculated. Moreover, it is advisable to provide a standard for rational decision making for new R&D investments since it is possible to determine investment priorities among a large number of candidates.