• Title/Summary/Keyword: Quaternary amine

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Studies on the Distribution Coefficient of the Primary, Secondary, Tertiary Amine and Quaternary Ammonium-methylorange Salts

  • Kim, Bak-Kwang
    • YAKHAK HOEJI
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    • v.18 no.3
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    • pp.183-189
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    • 1974
  • Distribution coefficients between nitrobanzene solution and deionized water, show a straight line when the number of alkyl radicals against the logarithm of distribution coefficient of the salts was plotted. After extracting salts of the indicator and the cationic surfactants with organic solvents, and employing the colorimetric method was used. A calculation method of distribution coefficients of the salts in the organic solvent has been suggested and it could be used for the extraction equilibrium of the primary amine, $CH_{3}(CH_2)_{n}NH_3^+$ secondary amine, $CH_{3}(CH_2)_{n}NH_{2}(CH_3)^+$, tertiary amine $CH_{3}(CH_2)_{n}NH(CH_3)_2^+$ and quaternary ammonium, $CH_{3}(CH_2)_{n}N(CH_3)_3^+$MO$^-$salts, (n=3,5,7,11).

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Studies on the Chemical Analysis of the Tertiary Amine Salt and Quaternary Ammonium Salt by Tetrathiocyanatocobaltate[II] (3급 아민염 및 4급 암모늄염의 Tetrathiocyanatocobaltate[II]에 의한 분석화학적 연구)

  • 엄동옥;이윤중
    • YAKHAK HOEJI
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    • v.24 no.3_4
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    • pp.159-165
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    • 1980
  • Tetrathiocyanatocobaltate[II] forms complexes with tertiary amine salts or quarternary ammonium salts which were extractable from aqueous solution by organic solvent. In order to study composition of the complex, the colored crystalline complexes produced were evaluated with elemental analysis, infrared and mass spectra. And also a novel spectrophotometric method for the determination of tertiary amine salt or quarternary ammonium salt with tetrathiocyanatocobaltate[II] was established by organic solvent extraction within coefficient of variation of 1.06-1.35%.

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Determination of Trace Copper in Seawater by Solvent Extraction and Atomic Absorption Spectrometry (용매추출과 원자 흡수분리법에 의한 해수중의 미량 구리의 정량)

  • 박종안;정창웅
    • Journal of Environmental Health Sciences
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    • v.19 no.2
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    • pp.40-45
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    • 1993
  • A solvent extraction system of copper-thiocyanate complex into various types of alkylamines such as secondary, tertiary and quaternary ammonium salt for the determination of trace copper by atomic absorption spectrometry is presented. The maximum extraction of copper shows at 0.1 M-thiocyanate and single extraction with 10 ml of 1% amine-MIBK from 50 ml of aqueous solution is enough to be quantitative for micro amounts of copper. The effect of amine diluents and of diverse ions are also examined.

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Quaternized Polyamidoamine Dendrimers as Novel Gene Delivery System: Relationship between Degree of Quaternization and Their Influences

  • Lee, Jung-Hoon;Lim, Yong-Beom;Choi, Joon-Sig;Choi, Myung-Un;Yang, Chul-Hak;Park, Jong-Sang
    • Bulletin of the Korean Chemical Society
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    • v.24 no.11
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    • pp.1637-1640
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    • 2003
  • Quaternary ammonium groups were introduced to Starburst polyamidoamine (PAMAM) dendrimers for a gene carrier. These quaternary dendritic carriers exhibited reduced cytotoxicity on 293T cells compared to parent dendrimers examined and their transfection efficiency were similar with parent dendrimers. Quaternization could be a promising tool to improve properties of dendrimers as a gene delivery carrier.

Synthesis and In Vitro Antibacterial Activity of Quaternary Ammonium Cephalosporin Derivatives Bearing Oxazolidinone Moiety

  • Chung, In-Hwa;Kim, Choong-Sup;Seo , Jae-Hong;Chung, Bong-Young
    • Archives of Pharmacal Research
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    • v.22 no.6
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    • pp.579-584
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    • 1999
  • Several oxazolidinones having amine moiety were prepared to form a quaternay ammonium salt with cephalosporin nucleus, and antibacterial activity of the quaternary ammonium cephalosporin derivatives bearing oxazolidinone moiety were examined particularly with expectation of dual activity. However, the cephalosporin-oxazolidinone compounds revealed rather weaker antibacterial activity in vitro than their parent oxazolidinone and cephalosporin without showing any characteristic activity as expected.

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Simultaneous determination of low molecular weight amines and quaternary ammonium ions by IC/ESI-MS

  • Jung, Joo-Young;Park, Han-Seok;Kim, Kang-Jin
    • Analytical Science and Technology
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    • v.20 no.3
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    • pp.255-260
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    • 2007
  • A new method for the simultaneous determination of low molecular weight amines and quaternary ammonium ions based on the separation by IC with a suppressor and the detection by MS with ESI has been developed. The method has been applied to the analysis of a mixture containing tetramethylammonium ion, tetraethylammonium ion, tetrapropylammonium ion, triethanolamine, trimethylamine and triethylamine. The constituents were separated by isocratic elution using an IonPac CS17 column, a cation-exchange column, and detected by conductivity and mass spectrometry. The newly developed method for the six components demonstrated that the repeatability in terms of relative standard deviation for three measurements was in the range of 0.1-0.5 %. The detection limits were between 0.2 and $0.9{\mu}g/mL$ by the IC/ESI-MS.

Synthesis and Surface Activity of New Quaternary Ammonium Salts Prepared from 2-Chloromethyl-5-(2-Phenylthiazol-4-yl)-1,3,4-Oxadiazole (2-클로로메틸-5-(2-Phenylthiazol-4-yl)-1,3,4-옥사디아졸의 새로운 4급 암모늄염의 합성과 계면활성도)

  • Bae, Sun Kun;Yeon, Young Heum
    • Applied Chemistry for Engineering
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    • v.17 no.3
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    • pp.286-290
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    • 2006
  • New quaternary ammonium chlorides, [alkyldimethyl-[5-(2-phenylthiazol-4-yl]-1,3,4-oxadizol-2-ylmethyl]quaternary ammonium chlorides (ADOQACs): 6] were obtained with high yields by the reaction of compound 5 with N,N-dimethylalkyl amines in isopropyl alcohol. The structures and physical properties of the synthesized compounds were investigated and those surface-active properties were measured. The surface tension ($\gamma_{cmc}$) and the minimal inhibitory concentration (MIC) of compound 6 were found to be influenced by the number of alkyl chain carbon. Especially, compounds 6c and 6d exhibited high anti-bacterial activities and good surface-active properties.