• 제목/요약/키워드: Quantitative Trait

검색결과 324건 처리시간 0.029초

일부 대학생의 체형 만족 정도와 식사 장애 위험 정도의 관계 연구 (Study on Association between Risk of Eating Disorder and Self-Esteem on Body Image)

  • 남희정;김영순
    • 한국식품영양학회지
    • /
    • 제18권2호
    • /
    • pp.115-126
    • /
    • 2005
  • This Quantitative study was investigated to examine the relationship between self-esteem on body image and disordered eating patterns in some university students. This study used a cross-sectional study design. Total 347 students participated in this study (88 male and 259 female) among three universities. The assessment of eating disorder was conducted by Eating Attitudes Test (EAT-26), a score of >or=20 identified individuals likely have an eating disorder, including anorexia nervosa and bulimia nervosa. Ideal body weight and current body weight were completed with self-evaluation. A distorted body image was independently related to the eating problem in the Logistic regression analysis. There were stronger relationships between their EAT-26 scores and their expected weight changes and weight control behaviors. Compared with the men, women showed highly wishful to loss for current body weight. In the relationship between score of EAT-26 and BMI distance by sex, levels of eating disorder showed linearly elevated toward increased BMI distance (Ideal BMI-Current BMI) (F-value=18.794, p<0.0001) in women, but there were not significant in men (F-value=2.028, p>0.05). In estimate on state-trait anxiety inventory according to quartile of BMI distance by sex, levels of state-trait anxiety were not significant difference by degree of body dissatisfaction in all sex. In addition, higher distorted body image was significantly increased numbers of weight control method and experience of side effects in female, but there were not showed significant relation between two variables in male.

일부 대학생의 식사 장애 위험 정도에 따른 체중 조절 방법 (Weight Control History according to Risk of Eating Disorder)

  • 남희정;김영순
    • 한국식품영양학회지
    • /
    • 제19권2호
    • /
    • pp.111-125
    • /
    • 2006
  • This quantitative study was conducted to examine the relationship between weight control behaviors and disordered eating patterns in some university students. This study used a cross-sectional study design. A total of 347 students from three universities participated in this study (88 male and 259 female) Eating disorders were assessed using the Eating Attitudes Test (EAT-26); a score of =20 identifies individuals who likely have an eating disorder, including anorexia nervosa and bulimia nervosa. A score for healthy dietary behaviors was obtained by self-assessment on a healthy diet scale (20-item questionnaire), and the severity of any state-trait anxiety was calculated by the state-trait anxiety inventory (40-item questionnaire). In the analyzed results, the percentage of participants with experience of weight control was 58% in male and 73% in female. The subjects with a high risk of an eating disorder (score of =20 of EAT-26) were 44.3% ($mean{\pm}S.D;\;18.9{\pm}13.4$) of the males, and 57.9% ($mean{\pm}S.D;\;23.2{\pm}11.6$) of the females. Higher Body Mass Index (BMI) was significantly related with an increased risk for an eating disorder in females, but not in males. In the group who had attempted weight control of all types, there was a severe risk of an eating disorder. Increased eating disorder risk was significantly related with weight control behaviors such as a higher number of attempts at weight control, having used medication, having experienced side effects, and having experienced disease for both sexes. Therefore, the results of this paper showed that detrimental behaviors of weight control are connected to an increased risk of eating disorders. Consequently, education regarding the correct, behaviors of weight control is necessary to prevent eating disorders in adolescents.

Genome-Wide Association Studies Associated with Backfat Thickness in Landrace and Yorkshire Pigs

  • Lee, Young-Sup;Shin, Donghyun
    • Genomics & Informatics
    • /
    • 제16권3호
    • /
    • pp.59-64
    • /
    • 2018
  • Although pork quality traits are important commercially, genome-wide association studies (GWASs) have not well considered Landrace and Yorkshire pigs worldwide. Landrace and Yorkshire pigs are important pork-providing breeds. Although quantitative trait loci of pigs are well-developed, significant genes in GWASs of pigs in Korea must be studied. Through a GWAS using the PLINK program, study of the significant genes in Korean pigs was performed. We conducted a GWAS and surveyed the gene ontology (GO) terms associated with the backfat thickness (BF) trait of these pigs. We included the breed information (Yorkshire and Landrace pigs) as a covariate. The significant genes after false discovery rate (<0.01) correction were AFG1L, SCAI, RIMS1, and SPDEF. The major GO terms for the top 5% of genes were related to neuronal genes, cell morphogenesis and actin cytoskeleton organization. The neuronal genes were previously reported as being associated with backfat thickness. However, the genes in our results were novel, and they included ZNF280D, BAIAP2, LRTM2, GABRA5, PCDH15, HERC1, DTNBP1, SLIT2, TRAPPC9, NGFR, APBB2, RBPJ, and ABL2. These novel genes might have roles in important cellular and physiological functions related to BF accumulation. The genes related to cell morphogenesis were NOX4, MKLN1, ZNF280D, BAIAP2, DNAAF1, LRTM2, PCDH15, NGFR, RBPJ, MYH9, APBB2, DTNBP1, TRIM62, and SLIT2. The genes that belonged to actin cytoskeleton organization were MKLN1, BAIAP2, PCDH15, BCAS3, MYH9, DTNBP1, ABL2, ADD2, and SLIT2.

QTL Analysis of Soybean Seed Weight Using RAPD and SSR Markers

  • Chung, Jong-Il;Ko, Mi-Suk;Kang, Jin-Ho
    • Plant Resources
    • /
    • 제3권3호
    • /
    • pp.184-193
    • /
    • 2000
  • Soybean [Glycine max (L.) Merr.] seed weight is a important trait in cultivar development. Objective of this study was to identify and confirm quantitative trait loci (QTLs) for seed weight variation in the F2 and F2:3 generations. QTLs for seed weight were identified in F2 and F2:3 generations using interval mapping (MapMaker/QTL) and single-factor analysis of variance (ANOVA). In the F2 plant generation (i.e., F3 seed), three markers, OPL9a, OPM7a, and OPAC12 were significantly (P<0.01) associated with seed weight QTLs. In the F2:3 plant row generation (i.e., F4 seed), five markers, OPA9a, OPG19, OPL9b, OPP11, and Sat_085 were significantly (P<0.01) associated with seed weight QTLs. Two markers, OPL9a and OPL9b were significantly (P<0.05) associated with seed weight QTLs in both generations. Two QTLs on USDA soybean linkage group C1 and R were identified in both F2 and F2:3 generations using interval mapping. The linkage group C1 QTL explained 16% of the variation in seed weight in both generations, and the linkage group R QTL explained 39% and 41% of the variation for F2 and F2:3 generation, respectively. The linkage group C2 QTL identified in F2:3 generation explained 14.9% of variation. Linkage groups C1, C2 and R had previously been identified as harbouring seed size QTLs. The consistency of QTLs across generations and populations indicates that marker-assisted selection is possible in a soybean breeding program.

  • PDF

New Sources of Resistance and Identification of DNA Marker Loci for Sheath Blight Disease Caused by Rhizoctonia solani Kuhn, in Rice

  • Pachai, Poonguzhali;Ashish, Chauhan;Abinash, Kar;Shivaji, Lavale;Spurthi N., Nayak;S.K., Prashanthi
    • The Plant Pathology Journal
    • /
    • 제38권6호
    • /
    • pp.572-582
    • /
    • 2022
  • Sheath blight disease caused by the necrotrophic, soilborne pathogen Rhizoctonia solani Kuhn, is the global threat to rice production. Lack of reliable stable resistance sources in rice germplasm pool for sheath blight has made resistance breeding a very difficult task. In the current study, 101 rice landraces were screened against R. solani under artificial epiphytotics and identified six moderately resistant landraces, Jigguvaratiga, Honasu, Jeer Sali, Jeeraga-2, BiliKagga, and Medini Sannabatta with relative lesion height (RLH) range of 21-30%. Landrace Jigguvaratiga with consistent and better level of resistance (21% RLH) than resistant check Tetep (RLH 28%) was used to develop mapping population. DNA markers associated with ShB resistance were identified in F2 mapping population developed from Jigguvaratiga × BPT5204 (susceptible variety) using bulk segregant analysis. Among 56 parental polymorphic markers, RM5556, RM6208, and RM7 were polymorphic between the bulks. Single marker analysis indicated the significant association of ShB with RM5556 and RM6208 with phenotypic variance (R2) of 28.29 and 20.06%, respectively. Co-segregation analysis confirmed the strong association of RM5556 and RM6208 located on chromosome 8 for ShB trait. This is the first report on association of RM6208 marker for ShB resistance. In silico analysis revealed that RM6208 loci resides the stearoyl ACP desaturases protein, which is involved in defense mechanism against plant pathogens. RM5556 loci resides a protein, with unknown function. The putative candidate genes or quantitative trait locus harbouring at the marker interval of RM5556 and RM6208 can be further used to develop ShB resistant varieties using molecular breeding approaches.

Genetic Insights into Domestication Loci Associated with Awn Development in Rice

  • Ngoc Ha Luong;Sangshetty G. Balkunde;Kyu-Chan Shim;Cheryl Adeva;Hyun-Sook Lee;Hyun-Jung Kim;Sang-Nag Ahn
    • 한국작물학회:학술대회논문집
    • /
    • 한국작물학회 2022년도 추계학술대회
    • /
    • pp.33-33
    • /
    • 2022
  • Rice (Oryza sativa L.) is a widely studied domesticated model plant. Seed awning is an unfavorable trait during rice harvesting and processing. Hence, awn was one of the target characters selected during domestication. However, the genetic mechanisms underlying awn development in rice are not well understood. In this study, we analyzed the genes for awn development using a mapping population derived from a cross between the Korean indica cultivar 'Milyang23' and NIL4/9 (derived from a cross between 'Hwaseong' and O. minuta). Two quantitative trait loci (QTLs), qAwn4 and qAwn9 were mapped on chromosome 4 and 9, respectively, increased awn length in an additive manner. Through comparative sequencing analyses parental lines, LABA1 was determined as the causal gene underlying qAwn4. qAwn9 was mapped to a 199-kb physical region between markers RM24663 and RM24679. Within this interval, 27 annotated genes were identified, and five genes, including a basic leucine zipper transcription factor 76 (OsbZIP76), were considered candidate genes for qAwn9 based on their functional annotations and sequence variations. Haplotype analysis using the candidate genes revealed tropical japonica specific sequence variants in the qAwn9 region, which partly explains the non-detection of qAwn9 in previous studies that used progenies from interspecific crosses. This provides further evidence that OsbZIP76 is possibly a causal gene for qAwn9. The O. minuta qAwn9 allele was identified as a major QTL associated with awn development in rice, providing an important molecular target for basic genetic research and domestication studies. Our results lay the foundation for further cloning of the awn gene underlying qAwn9.

  • PDF

치과내원환자의 성격특성에 따른 고객충성도 및 구전효과 연구 (A Study on Customer Loyalty and Word-of-Mouth Effect according to Character Trait of Patient in Dental Clinics)

  • 양해영
    • 한국산학기술학회논문지
    • /
    • 제12권12호
    • /
    • pp.5819-5826
    • /
    • 2011
  • 최근 치과 의료계는 장기화된 경기침체와 인력 공급 증가 및 의료기관의 양적 팽창, 의료소비자의 권리의식 향상과 의료소비 욕구의 다양화에 기인하여 의료산업의 경쟁이 심화되고 있다. 이로 인한 치과 의료기관 경영의 어려움은 치과 의료기관의 경쟁력 확보를 위한 노력을 요구하고 있다. 따라서 적은 비용으로 높은 마케팅 효과를 창출하는 구전 마케팅을 매스커뮤니케이션 마케팅의 새로운 대안으로 적극 활용해야할 필요가 있다. 이에 본 연구는 치과내원환자의 성격특성에 따른 고객충성도 및 구전효과 연구를 통해 치과 의료마케팅활동의 표적 집단을 정확히 파악하고 구전촉진요소를 제시함으로써 실무적 관점의 구전 마케팅 전략방안의 기초자료를 제시하고자 한다. 이를 위해 대구 소재 10개 치과의원을 대상으로 2011년 4월 11일부터 5월 6일 까지 4주 동안 설문을 통해 612부의 최종 분석 자료를 얻었다. 분석 결과는 다음과 같다. 대상자의 성격 특성에 따른 고객충성도 차이는 내 외 성향에서는 유의한 차이가 없었으며 마켓 메이븐 성향이 높게 나타난 대상자에게서 높은 고객충성도를 보였다(F=5.243, p=.006). 성격 특성에 따른 구전 효과 차이는 외향형의 대상자($x^2$=6.738, p=.006)와 마켓 메이븐 성향이 높은 대상자($x^2$=17.251, p=.000)에게서 더 많은 구전 경험 차이를 나타냈다. 본 연구 결과는 치과내원환자의 성격 특성에 따른 고객충성도 및 구전효과의 차별적 영향력을 밝히고 있으며 이를 통해 치과의료 마케팅 전략 수립에 있어 고려해야할 실무적 관점의 전략 수립 방안을 제시한 근거자료가 될 것이라 사료된다.

벼 RIL집단의 유전 분석과 농업형질 분석을 통한 도열병 저항성 QTL 탐색 및 유망계통 선발 (Genetic and Agronomic Analysis of a Recombinant Inbred Line Population to Map Quantitative Trait Loci for Blast Resistance and Select Promising Lines in Rice)

  • 하수경;정지웅;정종민;김진희;모영준
    • 한국작물학회지
    • /
    • 제65권3호
    • /
    • pp.172-181
    • /
    • 2020
  • 고시히카리는 도열병과 쓰러짐에 약하지만 밥맛 좋은 쌀로 유명하고, 육성된 지 60년이 넘은 지금까지도 일본에서 가장 많이 재배되는 품종이다. 고시히카리에 도열병에 강하면서 생육이 빠른 백일미를 교배한 RIL집단(KBRIL)에서 도열병 저항성에 대한 유전분석을 수행하여 저항성 유전자의 염색체 상 위치를 규명하고, 고시히카리의 우수한 미질을 보유하면서 도열병에도 강한 계통을 선발하기 위해 본 연구를 수행하였다. 주요 결과는 다음과 같다. 1. 고시히카리×백일미 RIL 394계통과 모·부본의 도열병 저항성(전주, 남원) 및 주요 농업형질을 조사하고, 유전 분석을 위해 사용된 142계통으로 총 130개 SNP 마커, 1,272.7cM의 유전자지도를 작성하였다. 도열병 저항성 QTL 분석 결과 전주에서는 1번 염색체의 qBL1.1이, 남원에서는 전주와 동일한 qBL1.1과 추가로 2번 염색체의 qBL2.1이 탐지되었다. 2. RIL 394계통의 qBL1.1과 qBL2.1 유전자형을 도출하고 각 QTL의 백일미 대립인자 집적에 의한 도열병 저항성 강화 효과를 관찰하였다. 전주에서는 qBL1.1의 경우에만 백일미 대립인자 집적에 의하여 도열병 저항성이 강화되었다. 반면 남원에서는 qBL1.1, qBL2.1 모두 백일미 대립인자가 집적될 때 도열병 저항성이 강화되었다. qBL1.1, qBL2.1은 출수기, 간장, 수장, 수수를 포함한 주요 농업형질에는 영향을 미치지 않았다. 3. 고시히카리×백일미 RIL 394계통 중에서 출수기와 간장을 기준으로 고시히카리와 유사하면서 도열병에 약/강한(KS/KR) 계통과 백일미와 유사하면서 도열병에 강한(BR) 계통을 각 15계통씩 선발하였다. KR 그룹은 완전 미율이 가장 우수하여 밥맛 검정, 수량성 등 추가조사를 통해 고시히카리의 우수한 밥맛을 지니면서 도열병 저항성을 보유한 고품질 밥쌀용 품종개발에 활용할 계획이다. 또한 BR그룹은 미질이 우수하면서 출수가 빠른 고품질 품종 개발에 유용할 것으로 기대된다.

고추 탄저병 저항성 관련 양적형질 유전자좌 분석 (Identification of Quantitative Trait Loci Associated with Anthracnose Resistance in Chili Pepper (Capsicum spp.))

  • 김수;김기택;김동휘;양은영;조명철;;채영;배도함;오대근;황주광
    • 원예과학기술지
    • /
    • 제28권6호
    • /
    • pp.1014-1024
    • /
    • 2010
  • 고추 탄저병은 국내외에서 고추 생산에 있어 많은 피해를 주는 병중의 하나로서, $Colletotrichum$ spp.에 의해 발생하며 현재 가장 많은 빈도를 나타내는 종은 $C.$ $acutatum$으로 보고되고 있다. 살균제에 대한 내성이 있는 것으로 보고되어 저항성 품종의 육성이 요구되어지고 있다. 본 연구의 목적은 $Capsicum$ $baccatum$ 종내 교잡을 통해 고추 탄저병 저항성 육종을 위한 MAS(marker assisted selection) 체계를 개발하는 기초연구로서 저항성과 관련한 QTL분석을 수행하였다. 저항성 검정결과 고추 탄저병저항성은 85%의 높은 광의의 유전력을 보였다. 양적형질 유전자좌 분석 결과 신뢰수준 이상의 LOD 수준을 보인 2개의 QTL($An8.1$, $An9.1$)이 탐색되었고, $R^2$가 2.04%와 14.36%이었다. 유전적인 효과는 $An8.1$은 상가적 효과가 0.46으로, $An9.1$은 상가적 효과가 -4.52로 나타났다. $An8.1$$An9.1$은 상처접종에 의해 나타나는 저항성 반응과 관련이 있는 것으로 생각되었다. 포장검정(08NR)과 관련한 QTL들은 신뢰수준이상의 LOD수준을 보이는 QTL은 탐색할 수 없었으나, $R^2$가 19.9%인 $An3.1$와 30.8%인 $An3.1$을 포함한 5개 QTL의 전체 $R^2$가 60.73%로 나타나 고추 탄저병저항성 유전과 관련한 인자가 다수 존재하는 것을 확인하였다. 따라서 이들 QTL은 더욱 정밀한 집단과 종간교잡 후대에서 적용성을 검정하여 고추 탄저병저항성 품종육성을 위한 MAS체계를 확립할 것이다.

Genome-wide association study of carcass weight in commercial Hanwoo cattle

  • Edea, Zewdu;Jeoung, Yeong Ho;Shin, Sung-Sub;Ku, Jaeul;Seo, Sungbo;Kim, Il-Hoi;Kim, Sang-Wook;Kim, Kwan-Suk
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제31권3호
    • /
    • pp.327-334
    • /
    • 2018
  • Objective: The objective of the present study was to validate genes and genomic regions associated with carcass weight using a low-density single nucleotide polymorphism (SNP) Chip in Hanwoo cattle breed. Methods: Commercial Hanwoo steers (n = 220) were genotyped with 20K GeneSeek genomic profiler BeadChip. After applying the quality control of criteria of a call rate ${\geq}90%$ and minor allele frequency (MAF) ${\geq}0.01$, a total of 15,235 autosomal SNPs were left for genome-wide association (GWA) analysis. The GWA tests were performed using single-locus mixed linear model. Age at slaughter was fitted as fixed effect and sire included as a covariate. The level of genome-wide significance was set at $3.28{\times}10^{-6}$ (0.05/15,235), corresponding to Bonferroni correction for 15,235 multiple independent tests. Results: By employing EMMAX approach which is based on a mixed linear model and accounts for population stratification and relatedness, we identified 17 and 16 loci significantly (p<0.001) associated with carcass weight for the additive and dominant models, respectively. The second most significant (p = 0.000049) SNP (ARS-BFGL-NGS-28234) on bovine chromosome 4 (BTA4) at 21 Mb had an allele substitution effect of 43.45 kg. Some of the identified regions on BTA2, 6, 14, 22, and 24 were previously reported to be associated with quantitative trait loci for carcass weight in several beef cattle breeds. Conclusion: This is the first genome-wide association study using SNP chips on commercial Hanwoo steers, and some of the loci newly identified in this study may help to better DNA markers that determine increased beef production in commercial Hanwoo cattle. Further studies using a larger sample size will allow confirmation of the candidates identified in this study.